ZA991716B - Pharmaceutical composition of topiramate. - Google Patents

Pharmaceutical composition of topiramate.

Info

Publication number
ZA991716B
ZA991716B ZA9901716A ZA991716A ZA991716B ZA 991716 B ZA991716 B ZA 991716B ZA 9901716 A ZA9901716 A ZA 9901716A ZA 991716 A ZA991716 A ZA 991716A ZA 991716 B ZA991716 B ZA 991716B
Authority
ZA
South Africa
Prior art keywords
topiramate
pharmaceutical composition
pharmaceutical
composition
Prior art date
Application number
ZA9901716A
Other languages
English (en)
Inventor
Madhav S Thakur
Pramod M Kotwal
Irwin S Gibbs
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22134079&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA991716(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of ZA991716B publication Critical patent/ZA991716B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
ZA9901716A 1998-03-04 1999-03-03 Pharmaceutical composition of topiramate. ZA991716B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7677098P 1998-03-04 1998-03-04

Publications (1)

Publication Number Publication Date
ZA991716B true ZA991716B (en) 2000-10-11

Family

ID=22134079

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9901716A ZA991716B (en) 1998-03-04 1999-03-03 Pharmaceutical composition of topiramate.

Country Status (32)

Country Link
US (4) US6696091B2 (xx)
EP (1) EP1066027B1 (xx)
JP (1) JP2003530295A (xx)
KR (1) KR20010041592A (xx)
CN (1) CN100364501C (xx)
AR (3) AR017984A1 (xx)
AT (1) ATE246490T1 (xx)
AU (1) AU763643B2 (xx)
BG (1) BG64885B1 (xx)
BR (1) BR9908488A (xx)
CA (1) CA2322644C (xx)
DE (1) DE69910186T2 (xx)
DK (1) DK1066027T3 (xx)
EA (1) EA200000814A1 (xx)
EE (1) EE04175B1 (xx)
ES (1) ES2204109T3 (xx)
HK (1) HK1032009A1 (xx)
HR (1) HRP20000563B1 (xx)
HU (1) HUP0301192A3 (xx)
ID (1) ID26982A (xx)
IL (2) IL138032A0 (xx)
MY (1) MY125821A (xx)
NO (1) NO20004311L (xx)
NZ (1) NZ506532A (xx)
PL (1) PL194559B1 (xx)
PT (1) PT1066027E (xx)
SK (1) SK285440B6 (xx)
TR (1) TR200002541T2 (xx)
TW (1) TW590778B (xx)
UA (1) UA65607C2 (xx)
WO (1) WO1999044581A2 (xx)
ZA (1) ZA991716B (xx)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6099865A (en) * 1998-07-08 2000-08-08 Fmc Corporation Croscarmellose taste masking
EP1158950B1 (en) 1999-02-17 2006-01-25 Ortho-Mcneil Pharmaceutical, Inc. Anticonvulsant derivatives useful in treating essential tremor
NZ514811A (en) * 1999-04-08 2005-01-28 Ortho Mcneil Pharm Inc Anticonvulsant derivatives useful in reducing blood glucose levels
ES2542868T3 (es) * 1999-06-14 2015-08-12 Vivus, Inc. Terapia de combinación para el tratamiento de diabetes asociada con la obesidad
EP1157682A1 (en) * 2000-05-25 2001-11-28 Cilag AG Blister package for topiramate tablets
WO2002003984A2 (en) * 2000-07-07 2002-01-17 Ortho-Mcneil Pharmaceutical, Inc. Anticonvulsant derivatives useful for treating and preventing the development of type ii diabetes mellitus and syndrome x
BR0115055A (pt) * 2000-10-30 2003-12-30 Ortho Mcneil Pharm Inc Terapia de combinação compreendendo agentes anticonvulsantes e antidiabéticos
US7771749B2 (en) 2001-07-11 2010-08-10 Monsanto Technology Llc Lignin-based microparticles for the controlled release of agricultural actives
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
WO2004010970A1 (en) * 2002-07-29 2004-02-05 Alza Corporation Formulations and dosage forms for controlled delivery of topiramate
US20050232995A1 (en) 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
JP2006511543A (ja) * 2002-12-13 2006-04-06 シラグ・アクチエンゲゼルシヤフト 安定なトピラメート製剤
CA2513064C (en) * 2003-01-31 2009-11-10 Elan Pharma International, Ltd. Nanoparticulate topiramate formulations
ITMI20031096A1 (it) * 2003-05-30 2004-11-30 Eurand Spa Microcapsule per coacervazione contenenti farmaco incorporato nel polimero di rivestimento
US6949518B1 (en) 2003-06-25 2005-09-27 Pao-Hsien Chu Methods for treating macular degeneration with topiramate
US20070154550A1 (en) * 2003-08-28 2007-07-05 Potdar Arti Pharmaceutical composition comprising anticonvulsant with taste mask coating
WO2005020959A2 (en) * 2003-09-02 2005-03-10 Alza Corporation Novel drug compositions and dosage forms of topiramate
JP4808392B2 (ja) * 2003-09-04 2011-11-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 苦味を隠蔽する薬理組成物
US20050244490A1 (en) * 2003-12-09 2005-11-03 Michael Otto Dosing methods for beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine antiviral therapy
MXPA06007511A (es) * 2003-12-29 2009-06-10 Johnson & Johnson Revestimientos de granulos de farmaco que imparten resistencia a la embarradura durante la compresion mecanica.
EP1701706A2 (en) * 2003-12-29 2006-09-20 Alza Corporation Novel drug compositions and dosage forms
WO2005065648A2 (en) * 2003-12-29 2005-07-21 Alza Corporation, Inc., Novel drug compositions and dosage forms of topiramate
MY147767A (en) 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
AU2006249577A1 (en) 2005-05-20 2006-11-30 Janssen Pharmaceutica N.V. Process for preparation of sulfamide derivatives
US8247018B2 (en) * 2005-06-20 2012-08-21 Authentiform Technologies, Llc Methods for quality control
EP1907988B1 (en) * 2005-06-20 2013-11-06 AuthentiForm Technologies, L.L.C. Systems and methods for product authentication
US7874489B2 (en) * 2005-06-20 2011-01-25 Authentiform Technologies, Llc Product authentication
CA2521272A1 (en) * 2005-10-04 2007-04-04 Bernard Charles Sherman Capsules comprising topiramate
AR058389A1 (es) 2005-12-19 2008-01-30 Janssen Pharmaceutica Nv Uso de derivados heterociclicos benzo-fusionados de sulfamida para el tratamiento de la obesidad
US8716231B2 (en) 2005-12-19 2014-05-06 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
US8497298B2 (en) 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
US8937096B2 (en) 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
US8691867B2 (en) 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
AU2007253814A1 (en) 2006-05-19 2007-11-29 Janssen Pharmaceutica N.V. Co-therapy for the treatment of epilepsy
US9744137B2 (en) * 2006-08-31 2017-08-29 Supernus Pharmaceuticals, Inc. Topiramate compositions and methods of enhancing its bioavailability
EP2061458B1 (en) * 2006-09-15 2014-12-10 Regents of the University of Minnesota Topiramate compositions and methods for their use
US20090239942A1 (en) * 2006-09-15 2009-09-24 Cloyd James C Topiramate Compositions and Methods of Making and Using the Same
AU2007319141B2 (en) 2006-11-17 2013-01-10 Supernus Pharmaceuticals Inc. Sustained-release formulations of topiramate
CN102114002B (zh) * 2006-12-04 2016-05-11 苏佩努斯制药公司 托吡酯的增强的立即释放制剂
MX2009006114A (es) * 2007-03-02 2009-11-10 Meda Pharmaceuticals Inc Composiciones que comprenden carisoprodol y metodos de uso de las mismas.
EP2143424A4 (en) * 2007-03-26 2013-07-31 Teikoku Seiyaku Kk ORAL PHARMACEUTICAL PREPARATION FOR SPECIFIC DELIVERY TO THE COLON
JP5424571B2 (ja) * 2007-04-12 2014-02-26 協和発酵キリン株式会社 トピラマート含有固形製剤
US20090076128A1 (en) * 2007-09-15 2009-03-19 Protia Llc Deuterium-enriched topiramate
EA018567B1 (ru) 2008-06-23 2013-08-30 Янссен Фармацевтика Нв Кристаллическая форма (2s)-(-)-n-(6-хлор-2,3-дигидробензо[1,4]диоксин-2-илметил)сульфамида
US8815939B2 (en) 2008-07-22 2014-08-26 Janssen Pharmaceutica Nv Substituted sulfamide derivatives
JP6133009B2 (ja) * 2010-08-11 2017-05-24 協和発酵キリン株式会社 トピラマート顆粒
JP4803686B2 (ja) * 2010-08-31 2011-10-26 協和発酵キリン株式会社 苦味を呈する薬物を含有する顆粒および口腔内崩壊錠
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
CN102579367B (zh) * 2012-03-23 2014-03-12 中国人民解放军军事医学科学院毒物药物研究所 托吡酯缓释药物组合物、其制备方法及用途
CN103316026B (zh) 2012-03-23 2016-05-11 中国人民解放军军事医学科学院毒物药物研究所 含芬特明和托吡酯的联合产品及其制备方法
US9457008B2 (en) 2012-03-23 2016-10-04 Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China Joint product comprising synephrine and topiramate
WO2014070958A1 (en) 2012-10-30 2014-05-08 Certirx Corporation Product, image, or document authentication, verification, and item identification
EP2968210A4 (en) * 2013-03-12 2016-12-28 Bio-Pharm Solutions Co Ltd PHENYL ACARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING PEDIATRIC EPILEPSY AND EPILEPSY-MEDIATED SYNDROME
US8652527B1 (en) * 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
MX365914B (es) 2013-03-15 2019-06-20 Aprecia Pharmaceuticals LLC Forma de dosificación de topiramato dispersable rápidamente.
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules
WO2014167439A1 (en) * 2013-03-26 2014-10-16 Wockhardt Limited Modified release pharmaceutical compositions of topiramate or salts thereof
US20160128943A1 (en) * 2013-06-04 2016-05-12 KVK-Tech, Inc. Controlled release caffeine dosage forms
CN104922075A (zh) * 2015-05-31 2015-09-23 黑龙江佰彤儿童药物研究有限公司 一种治疗儿童癫痫的固体制剂及其制备方法
EP3241549A1 (en) * 2016-05-02 2017-11-08 Sun Pharmaceutical Industries Limited Sprinkle composition of cinacalcet
EP3452023A1 (en) 2016-05-05 2019-03-13 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
EP3883546A1 (en) 2018-11-21 2021-09-29 Rosemont Pharmaceuticals Ltd Oral topiramate suspension formulations with extended shelf stability and enhanced bioavailability

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1509866A (en) 1975-06-10 1978-05-04 Johnson & Johnson Enteric coated digestive enzyme compositions
DD146547A5 (de) 1978-07-15 1981-02-18 Boehringer Sohn Ingelheim Arzneimittel-retardform mit unloeslichen poroesen diffusionshuellen
US4205060A (en) 1978-12-20 1980-05-27 Pennwalt Corporation Microcapsules containing medicament-polymer salt having a water-insoluble polymer sheath, their production and their use
DE3012136C2 (de) 1980-03-28 1984-02-16 Bauer, Kurt Heinz, Prof. Dr., 7800 Freiburg Verfahren zur Herstellung eines Granulats
JPS5758631A (en) * 1980-09-24 1982-04-08 Toyo Jozo Co Ltd Coating composition
EP0088635B1 (en) * 1982-03-10 1986-12-30 Toray Industries, Inc. Laminated film and magnetic recording medium made therewith
US4994260A (en) 1982-05-28 1991-02-19 Astra Lakemedel Aktiebolag Pharmaceutical mixture
US4505616A (en) * 1983-05-26 1985-03-19 Litton Systems, Inc. Self-locking chock system for a jack-up rig unit
US4513006A (en) * 1983-09-26 1985-04-23 Mcneil Lab., Inc. Anticonvulsant sulfamate derivatives
US4568559A (en) 1984-02-06 1986-02-04 Biotek, Inc. Composite core coated microparticles and process of preparing same
GB8403360D0 (en) 1984-02-08 1984-03-14 Erba Farmitalia Pharmaceutical compositions
GB8403359D0 (en) 1984-02-08 1984-03-14 Erba Farmitalia Pharmaceutical compositions
GB8403361D0 (en) 1984-02-08 1984-03-14 Erba Farmitalia Pharmaceutical composition
DE3405378A1 (de) 1984-02-15 1985-08-22 Röhm GmbH, 6100 Darmstadt Arzneimittelueberzug
GB8414220D0 (en) * 1984-06-04 1984-07-11 Sterwin Ag Medicaments in unit dose form
DE3440288A1 (de) 1984-11-05 1986-05-07 Gergely, Gerhard, Dr.-Ing., Wien Pharmazeutische zubereitung mit einem gehalt an mindestens einer schleimhautreizenden substanz oder dergleichen, insbesondere profen, sowie verfahren zu ihrer herstellung
IT1183574B (it) 1985-05-08 1987-10-22 Eurand Spa Metodo per ottenere una sospensione estemporanea omogenea di microcapsule
US5286489A (en) 1985-08-26 1994-02-15 The Procter & Gamble Company Taste masking compositions
US4800087A (en) 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
JPS63188621A (ja) 1987-01-30 1988-08-04 Taisho Pharmaceut Co Ltd 矯味経口製剤
GB8702411D0 (en) 1987-02-03 1987-03-11 Zyma Sa Swellable pellets
US4874613A (en) * 1987-03-06 1989-10-17 Baker Cummins Pharmaceuticals, Inc. Taste concealing pharmaceutical dosage unit
DK130287D0 (da) 1987-03-13 1987-03-13 Benzon As Alfred Oralt praeparat
FR2613619B1 (fr) 1987-04-07 1993-10-15 Recherche Informatique Pharmacie Medicaments, produits dietetiques ou produits d'hygiene sous forme de compositions pulverulentes obtenues par adsorption de principes actifs sur un sucre a dissolution rapide
US4994496A (en) 1987-09-09 1991-02-19 Repasky Elizabeth A Use of milk globules as carriers for drugs
NZ226822A (en) * 1987-11-16 1990-03-27 Mcneil Consumer Prod Chewable medicament tablet containing means for taste masking
US4851226A (en) 1987-11-16 1989-07-25 Mcneil Consumer Products Company Chewable medicament tablet containing means for taste masking
US4851266A (en) * 1988-05-31 1989-07-25 Akira Momose Surface treatment of powderfree surgical gloves
IT1226549B (it) * 1988-07-12 1991-01-24 Resa Farma Composizioni farmaceutiche ad attivita' analgesica ed antiinfiammatoria per uso orale, dotate di ottima palatabilita' ed esenti da effetti irritanti sulle mucose.
US4916161A (en) 1988-10-25 1990-04-10 Bristol-Myers Squibb Taste-masking pharmaceutical agents
US5013716A (en) 1988-10-28 1991-05-07 Warner-Lambert Company Unpleasant taste masking compositions and methods for preparing same
IT1227899B (it) 1988-12-23 1991-05-14 Poli Ind Chimica Spa Rivestimento totale o parziale di principi attivi farmaceutici e relative composizioni
US5275823A (en) 1989-04-27 1994-01-04 Smith Kline & French Laboratories Ltd. Pharmaceutical compositions
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5084278A (en) 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions
US5417985A (en) 1989-07-20 1995-05-23 Farmalyoc Solid and porous single dosage form comprising particles in the form of beads and its preparation
US5082669A (en) 1989-07-20 1992-01-21 Dainippon Pharmaceutical Co., Ltd. Rapid-releasing oral particle pharmaceutical preparation with unpleasant taste masked
JP3317444B2 (ja) * 1989-07-20 2002-08-26 大日本製薬株式会社 不快な味が遮蔽された速放性製剤
NZ234587A (en) 1989-08-04 1991-11-26 Mcneil Ppc Inc A chewable pharmaceutical tablet of compressed coated granules
DE3929166A1 (de) * 1989-09-02 1991-03-07 Basf Ag Verfahren zur herstellung magnetischer aufzeichnungstraeger
US4958252A (en) * 1990-01-16 1990-09-18 Westinghouse Electric Corp. Circuit breaker with rating plug having memory
US5206030A (en) 1990-02-26 1993-04-27 Fmc Corporation Film-forming composition and use for coating pharmaceuticals, foods and the like
IT1241417B (it) 1990-03-06 1994-01-14 Vectorpharma Int Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione
FR2660317B1 (fr) 1990-03-27 1994-01-14 Seppic Produit filmogene destine a l'enrobage des formes solides; son procede de fabrication et produits revetus de ce produit.
IT1246383B (it) 1990-04-17 1994-11-18 Eurand Int Metodo per il mascheramento del sapore di farmaci
US5460825A (en) 1990-05-23 1995-10-24 Mcneil-Ppc, Inc. Taste mask coatings for preparing chewable pharmaceutical tablets
US5075114A (en) * 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
US5260072A (en) * 1990-08-30 1993-11-09 Mcneil-Ppc, Inc. Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
CA2052679C (en) * 1990-08-30 1997-12-02 Edward J. Roche Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
CA2068402C (en) 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
IL103172A (en) * 1991-09-19 1997-01-10 Mcneilab Inc Preparation of chlorosulfate and sulfamate derivatives of 2, 3:4, 5-bis-o-(1-methylethylidene)-beta-d-fructopyranose and (1-methylcyclohexyl) methanol
DE4201179A1 (de) 1992-01-17 1993-07-22 Alfatec Pharma Gmbh Wirkstoff(e) enthaltendes granulat oder pellet mit einem geruest aus hydrophilen makromolekuelen und verfahren zu seiner herstellung
WO1993024109A1 (en) 1992-06-04 1993-12-09 Smithkline Beecham Corporation Palatable pharmaceutical compositions
PH30929A (en) 1992-09-03 1997-12-23 Janssen Pharmaceutica Nv Beads having a core coated with an antifungal and a polymer.
HU221308B1 (en) 1992-10-26 2002-09-28 Sanol Arznei Schwarz Gmbh Process for producing microcapsules
GB9224855D0 (en) * 1992-11-27 1993-01-13 Smithkline Beecham Plc Pharmaceutical compositions
US5354566A (en) 1993-06-02 1994-10-11 Kraft General Foods, Inc. Preparation of yeast-leavened dough crusts
CA2164344C (en) 1993-08-30 2004-06-29 Stanley Lech Tablet coating based on a melt-spun mixture of a saccharide and a polymer
US5425742A (en) * 1994-03-28 1995-06-20 Patrick S. Quigley Use of hollow hypobaric chambers on body parts for increasing blood flow, reducing pressure and decreasing pain
SE9402422D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New beads for controlled release and a pharmaceutical preparation containing the same
JPH0826977A (ja) * 1994-07-19 1996-01-30 Tanabe Seiyaku Co Ltd 溶出制御型経口製剤
US5705183A (en) 1994-11-16 1998-01-06 Phillips Company Cotton candy coated medication and a method for making and administering the same
US5560913A (en) 1995-01-27 1996-10-01 The Procter & Gamble Company Pharmaceutical compositions
US5607697A (en) * 1995-06-07 1997-03-04 Cima Labs, Incorporated Taste masking microparticles for oral dosage forms
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US5760007A (en) * 1997-07-16 1998-06-02 Ortho Pharmaceutical Corporation Anticonvulsant derivatives useful in treating neuropathic pain

Also Published As

Publication number Publication date
DK1066027T3 (da) 2003-11-10
PT1066027E (pt) 2003-12-31
PL343894A1 (en) 2001-09-10
US6696091B2 (en) 2004-02-24
DE69910186D1 (de) 2003-09-11
CN100364501C (zh) 2008-01-30
BG64885B1 (bg) 2006-08-31
JP2003530295A (ja) 2003-10-14
PL194559B1 (pl) 2007-06-29
HUP0301192A3 (en) 2004-03-01
CN1419444A (zh) 2003-05-21
EE200000503A (et) 2002-02-15
KR20010041592A (ko) 2001-05-25
ES2204109T3 (es) 2004-04-16
SK285440B6 (sk) 2007-01-04
WO1999044581A2 (en) 1999-09-10
CA2322644A1 (en) 1999-09-10
AR017984A1 (es) 2001-10-24
NO20004311L (no) 2000-10-25
AU763643B2 (en) 2003-07-31
HRP20000563A2 (en) 2001-04-30
EE04175B1 (et) 2003-12-15
AR048456A2 (es) 2006-04-26
US20040156901A1 (en) 2004-08-12
TW590778B (en) 2004-06-11
AU2798999A (en) 1999-09-20
MY125821A (en) 2006-08-30
CA2322644C (en) 2005-07-26
EA200000814A1 (ru) 2001-02-26
SK13062000A3 (sk) 2001-04-09
UA65607C2 (uk) 2004-04-15
NO20004311D0 (no) 2000-08-30
HRP20000563B1 (en) 2009-07-31
ID26982A (id) 2001-02-22
US7125560B2 (en) 2006-10-24
IL138032A (en) 2007-09-20
US20020064563A1 (en) 2002-05-30
IL138032A0 (en) 2001-10-31
HK1032009A1 (en) 2001-07-06
US20060286163A1 (en) 2006-12-21
HUP0301192A2 (hu) 2003-08-28
ATE246490T1 (de) 2003-08-15
DE69910186T2 (de) 2004-07-29
EP1066027B1 (en) 2003-08-06
EP1066027A1 (en) 2001-01-10
BG104727A (en) 2001-05-31
NZ506532A (en) 2003-08-29
WO1999044581A3 (en) 2003-07-17
BR9908488A (pt) 2000-12-05
TR200002541T2 (tr) 2001-03-21
US20080260813A1 (en) 2008-10-23
AR048457A2 (es) 2006-04-26

Similar Documents

Publication Publication Date Title
ZA991716B (en) Pharmaceutical composition of topiramate.
HUP9901606A2 (en) Pharmaceutical compositions comprising sildenaphil
CZ20011518A3 (cs) Farmaceutický prostředek
HUP0103507A3 (en) Pharmaceutical compositions comprising 2-quinolones
GB9827996D0 (en) Pharmaceutical Compositions
HUP0102483A3 (en) Pharmaceutical compositions containing androst-5-ene-3betha,17betha-diol
HK1027957A1 (en) Pharmaceutical composition.
HK1038884A1 (en) Medicinal compositions.
PT1466615E (pt) Composição farmacêutica
PL343769A1 (en) Pharmaceutical composition
GB9809213D0 (en) Pharmaceutical compositions
GB9818591D0 (en) Pharmaceutical composition
ZA989680B (en) Pharmaceutical composition.
HK1022853A1 (en) Pharmaceutical compositions.
ZA987392B (en) Pharmaceutical composition.
HK1040191A1 (zh) 具有改良味道的藥物組合物
ZA991232B (en) New compound and pharmaceutical compositions thereof.
HK1044117B (zh) 藥物組合物
ZA99890B (en) Pharmaceutical compositions.
GB9806487D0 (en) Pharmaceutical compositions
HU9800078D0 (en) Pharmaceutical composition
SI1066027T1 (en) Pharmaceutical composition of topiramate
ZA997202B (en) Pharmaceutical composition.
HU9801772D0 (en) Pharmaceutical composition
GB9818233D0 (en) Pharmaceutical composition