ZA98977B - Lactose-free non-hygroscopic anhydrous pharmaceutical compositions of descarboethoxyloratadine - Google Patents

Lactose-free non-hygroscopic anhydrous pharmaceutical compositions of descarboethoxyloratadine

Info

Publication number
ZA98977B
ZA98977B ZA98977A ZA98977A ZA98977B ZA 98977 B ZA98977 B ZA 98977B ZA 98977 A ZA98977 A ZA 98977A ZA 98977 A ZA98977 A ZA 98977A ZA 98977 B ZA98977 B ZA 98977B
Authority
ZA
South Africa
Prior art keywords
descarboethoxyloratadine
lactose
pharmaceutical compositions
anhydrous pharmaceutical
free non
Prior art date
Application number
ZA98977A
Other languages
English (en)
Inventor
Paul D Rubin
Martin P Redmon
Stephen A Wald
Hal T Butler
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27365195&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA98977(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sepracor Inc filed Critical Sepracor Inc
Publication of ZA98977B publication Critical patent/ZA98977B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
    • A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
ZA98977A 1997-02-07 1998-02-06 Lactose-free non-hygroscopic anhydrous pharmaceutical compositions of descarboethoxyloratadine ZA98977B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3732597P 1997-02-07 1997-02-07
US4518497P 1997-04-30 1997-04-30
US5305097P 1997-07-21 1997-07-21

Publications (1)

Publication Number Publication Date
ZA98977B true ZA98977B (en) 1998-07-30

Family

ID=27365195

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA98977A ZA98977B (en) 1997-02-07 1998-02-06 Lactose-free non-hygroscopic anhydrous pharmaceutical compositions of descarboethoxyloratadine

Country Status (29)

Country Link
US (2) US20020123504A1 (ko)
EP (2) EP0969836B1 (ko)
JP (1) JP2001511184A (ko)
KR (5) KR100624259B1 (ko)
CN (1) CN1132579C (ko)
AR (3) AR011114A1 (ko)
AT (1) ATE345133T1 (ko)
AU (1) AU6271998A (ko)
BR (1) BR9806157A (ko)
CA (1) CA2267136C (ko)
CO (1) CO4940445A1 (ko)
CZ (1) CZ119499A3 (ko)
DE (1) DE69836424T2 (ko)
DK (1) DK0969836T3 (ko)
ES (1) ES2271986T3 (ko)
HK (1) HK1024187A1 (ko)
HU (1) HUP0001527A3 (ko)
MY (1) MY136999A (ko)
NO (2) NO325611B1 (ko)
NZ (1) NZ335041A (ko)
PE (1) PE71699A1 (ko)
PL (1) PL192075B1 (ko)
PT (1) PT969836E (ko)
RU (1) RU2209627C2 (ko)
SK (1) SK286035B6 (ko)
TW (1) TW522014B (ko)
UA (1) UA70290C2 (ko)
WO (1) WO1998034614A1 (ko)
ZA (1) ZA98977B (ko)

Families Citing this family (33)

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DE69916042T2 (de) * 1998-07-10 2004-11-11 Schering Corp. Orale zusammensetzungen mit 8-chloro-6,11-dihydro-11-(4-piperidyliden)-5h-benzo[5,6]cyclohepta[1,2-b]pyridin
US6100274A (en) * 1999-07-07 2000-08-08 Schering Corporation 8-chloro-6,11-dihydro-11- ](4-piperidylidine)-5H-benzo[5,6]cyclohepta[1,2-bpyridine oral compositions
AU7589700A (en) * 1999-09-22 2001-04-24 Schering Corporation Treating allergic and inflammatory conditions
US6114346A (en) * 1999-10-22 2000-09-05 Schering Corporation Treating sleep disorders using desloratadine
MY125516A (en) 1999-11-16 2006-08-30 Smithkline Beecham Plc Novel composition based on thiazolidinedione and metformin and use
AU2277101A (en) 1999-12-20 2001-07-03 Schering Corporation Stable extended release oral dosage composition
KR101199654B1 (ko) * 1999-12-20 2012-11-08 머크 샤프 앤드 돔 코포레이션 안정한 서방출형의 경구 투여용 조성물
SK287105B6 (sk) 1999-12-20 2009-12-07 Schering Corporation Dvojvrstvový orálny dávkový prostriedok s predĺženým uvoľňovaním
US7405223B2 (en) 2000-02-03 2008-07-29 Schering Corporation Treating allergic and inflammatory conditions
US20060135547A1 (en) * 2003-03-12 2006-06-22 Toth Zoltan G Stable pharmaceutical compositions of desloratadine and processes for preparation of polymorphic forms of desloratadine
ES2232331T1 (es) * 2003-03-12 2005-06-01 Biogal Gyogyszergyar Rt. Procedimientos para la preparacion de formas polimorficas de desloratadina.
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
EP1696881A2 (en) * 2003-12-23 2006-09-06 Sun Pharmaceutical Industries Limited Stable oral composition
TWI415635B (zh) 2004-05-28 2013-11-21 必治妥施貴寶公司 加衣錠片調製物及製備彼之方法
AU2005263958B2 (en) * 2004-07-16 2011-04-14 Cipla Limited Anti-histaminic composition
WO2006020534A2 (en) * 2004-08-09 2006-02-23 Dr. Reddy's Laboratories Ltd. Stabilized desloratadine composition
US20070004671A1 (en) * 2005-05-20 2007-01-04 Agarwal Sudeep K Stable desloratadine compositions
EP1728513A3 (en) * 2005-05-20 2007-10-31 Dr. Reddy's Laboratories, Inc. Stable desloratadine compositions
US20070014855A1 (en) * 2005-07-12 2007-01-18 Rahul Gawande S Stable desloratadine compositions
US20080118555A1 (en) * 2005-10-20 2008-05-22 Glenmark Pharmaceuticals Limited Stable pharmaceutical composition containing desloratadine
CA2541045A1 (en) * 2006-03-24 2007-09-24 Pharmascience Inc. A descarbonylethoxyloratadine containing pharmaceutical composition
EP1862462A1 (en) * 2006-04-10 2007-12-05 Ranbaxy Laboratories Limited Process for the preparation of desloratadine
WO2007140987A1 (en) * 2006-06-07 2007-12-13 Sandoz Ag Stable and bioavailable formulations and a novel form of desloratadine
ECSP077628A (es) 2007-05-03 2008-12-30 Smithkline Beechman Corp Nueva composición farmacéutica
TR200806298A2 (tr) 2008-08-22 2010-03-22 Bi̇lgi̇ç Mahmut Farmasötik formülasyon
EA024980B1 (ru) 2009-02-17 2016-11-30 КРКА, д.д., НОВО МЕСТО Лекарственные формы, содержащие основание прасугреля или его фармацевтически приемлемые соли присоединения кислоты, и способы их приготовления
ATE525064T1 (de) 2009-07-01 2011-10-15 Tiefenbacher Alfred E Gmbh & Co Kg Pharmazeutische zusammensetzung mit desloratadin
WO2011141483A2 (en) 2010-05-10 2011-11-17 Laboratorios Lesvi, S.L. Stable pharmaceutical formulations containing an antihistaminic
TR201009396A2 (tr) 2010-11-11 2012-05-21 Bi̇lgi̇ç Mahmut Desloratadin granüller
CN102813640B (zh) * 2012-09-06 2016-12-21 无锡万全医药技术有限公司 一种含地氯雷他定的软胶囊及其制备方法
US20170135969A1 (en) 2015-11-12 2017-05-18 Jds Therapeutics, Llc Topical arginine-silicate-inositol for wound healing
EP3506895A4 (en) 2016-09-01 2020-04-15 JDS Therapeutics, LLC MAGNESIUM BIOTINATE COMPOSITIONS AND METHODS OF USE
CN113230235B (zh) * 2021-04-15 2022-11-11 海南普利制药股份有限公司 含地氯雷他定的复方缓释胶囊及其制备方法

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HU194864B (en) * 1984-02-15 1988-03-28 Schering Corp Process for production of 8-chlor-6,11-dihydro-11-(4-piperidilidene)-5h-benzo (5,6)-cyclo-hepta (1,2-b) pyridine and its salts
US4990535A (en) * 1989-05-03 1991-02-05 Schering Corporation Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine
JPH06504772A (ja) * 1990-12-18 1994-06-02 ザ　ウエルカム　ファウンデーション　リミテッド 抗癌剤の薬効を増強し抗多剤耐性を有する薬剤
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US5314697A (en) * 1992-10-23 1994-05-24 Schering Corporation Stable extended release oral dosage composition comprising loratadine and pseudoephedrine
DE4442999A1 (de) * 1994-12-02 1996-06-05 Hexal Pharma Gmbh Pharmazeutische Zusammensetzung mit einem aktiven Loratidin-Metaboliten
US5595997A (en) * 1994-12-30 1997-01-21 Sepracor Inc. Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
US5939426A (en) * 1997-02-28 1999-08-17 Sepracor Inc. Methods for treating urinary incontinence using descarboethoxyloratadine
US6162829A (en) * 1997-10-17 2000-12-19 Atlantic Pharmaceuticals, Inc. (3R,4R)-Δ8 -tetrahydrocannabinol-11-oic acids useful as antiinflammatory agents and analgesics
US5997905A (en) * 1998-09-04 1999-12-07 Mcneil-Ppc Preparation of pharmaceutically active particles

Also Published As

Publication number Publication date
ATE345133T1 (de) 2006-12-15
CZ119499A3 (cs) 1999-08-11
KR100624259B1 (ko) 2006-09-13
PL192075B1 (pl) 2006-08-31
MY136999A (en) 2008-12-31
EP1614421A3 (en) 2006-02-15
NO325611B1 (no) 2008-06-23
SK286035B6 (sk) 2008-01-07
US20020123504A1 (en) 2002-09-05
PL334232A1 (en) 2000-02-14
KR20060076330A (ko) 2006-07-04
CN1132579C (zh) 2003-12-31
NO992157D0 (no) 1999-05-04
CO4940445A1 (es) 2000-07-24
AR064896A2 (es) 2009-05-06
PE71699A1 (es) 1999-08-03
PT969836E (pt) 2007-01-31
HUP0001527A2 (hu) 2001-04-28
AU6271998A (en) 1998-08-26
KR20080003012A (ko) 2008-01-04
AR011114A1 (es) 2000-08-02
EP1614421A2 (en) 2006-01-11
DE69836424D1 (de) 2006-12-28
KR20000068914A (ko) 2000-11-25
CN1246794A (zh) 2000-03-08
US20060079489A1 (en) 2006-04-13
AR064895A2 (es) 2009-05-06
EP0969836B1 (en) 2006-11-15
EP0969836A1 (en) 2000-01-12
RU2209627C2 (ru) 2003-08-10
TW522014B (en) 2003-03-01
UA70290C2 (uk) 2004-10-15
BR9806157A (pt) 2001-01-09
DE69836424T2 (de) 2007-09-27
DK0969836T3 (da) 2007-03-19
CA2267136C (en) 2000-11-28
NO20075846L (no) 1999-05-04
WO1998034614A1 (en) 1998-08-13
ES2271986T3 (es) 2007-04-16
HK1024187A1 (en) 2000-10-05
NZ335041A (en) 2000-09-29
HUP0001527A3 (en) 2002-01-28
SK47299A3 (en) 2000-03-13
NO992157L (no) 1999-05-04
KR20070086880A (ko) 2007-08-27
JP2001511184A (ja) 2001-08-07
KR20060132053A (ko) 2006-12-20

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