ZA987445B - New optically pure analogues of camptothecin new optically pure synthetic intermediate and their preparation process - Google Patents

New optically pure analogues of camptothecin new optically pure synthetic intermediate and their preparation process

Info

Publication number
ZA987445B
ZA987445B ZA987445A ZA987445A ZA987445B ZA 987445 B ZA987445 B ZA 987445B ZA 987445 A ZA987445 A ZA 987445A ZA 987445 A ZA987445 A ZA 987445A ZA 987445 B ZA987445 B ZA 987445B
Authority
ZA
South Africa
Prior art keywords
optically pure
new optically
camptothecin
preparation process
analogues
Prior art date
Application number
ZA987445A
Other languages
English (en)
Inventor
Jean-Bernard Cazaux
Christine Le Breton
Dennis Bigg
Olivier Lavergne
Eric Manginot
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of ZA987445B publication Critical patent/ZA987445B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA987445A 1997-08-29 1998-08-18 New optically pure analogues of camptothecin new optically pure synthetic intermediate and their preparation process ZA987445B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9710785A FR2768431B1 (fr) 1997-08-29 1997-08-29 Nouveaux analogues optiquement purs de la camptothecine, nouvel intermediaire de synthese optiquement pur et son procede de preparation

Publications (1)

Publication Number Publication Date
ZA987445B true ZA987445B (en) 1999-02-17

Family

ID=9510590

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA987445A ZA987445B (en) 1997-08-29 1998-08-18 New optically pure analogues of camptothecin new optically pure synthetic intermediate and their preparation process

Country Status (25)

Country Link
EP (2) EP1007527B1 (cs)
JP (1) JP2001514261A (cs)
KR (1) KR100570254B1 (cs)
CN (3) CN1195758C (cs)
AR (1) AR016856A1 (cs)
AT (1) ATE253069T1 (cs)
AU (1) AU760863B2 (cs)
BR (1) BR9811405A (cs)
CA (1) CA2301739C (cs)
CZ (1) CZ297896B6 (cs)
DE (1) DE69819340T2 (cs)
DK (1) DK1007527T3 (cs)
ES (1) ES2209196T3 (cs)
FR (1) FR2768431B1 (cs)
HR (1) HRP20000110A2 (cs)
HU (1) HUP0003429A3 (cs)
IL (2) IL134437A0 (cs)
NO (1) NO324882B1 (cs)
NZ (1) NZ502862A (cs)
PL (1) PL195289B1 (cs)
PT (1) PT1007527E (cs)
RU (1) RU2233283C2 (cs)
TW (1) TW419479B (cs)
WO (1) WO1999011646A1 (cs)
ZA (1) ZA987445B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790261B1 (fr) 1999-02-26 2004-09-10 Sod Conseils Rech Applic Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation
US6207832B1 (en) 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
US6372906B1 (en) 2001-04-12 2002-04-16 University Of Pittsburgh Synthesis of silyl camptothecins and silyl homocamptothecins
US6723853B2 (en) 2001-08-27 2004-04-20 University Of Pittsburgh Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
CN100408582C (zh) * 2004-02-12 2008-08-06 中国人民解放军第二军医大学 高喜树碱类化合物及其制备方法和用途
WO2006033011A1 (en) * 2004-09-21 2006-03-30 Societe De Conseils De Recherches Et D'applications Scientifique (S.C.R.A.S.) Novel processes for the production of useful intermediates
CN100465175C (zh) * 2005-11-29 2009-03-04 中国人民解放军第二军医大学 7-位取代高喜树碱类化合物及作为药物的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3008226B2 (ja) * 1991-01-16 2000-02-14 第一製薬株式会社 六環性化合物
US5459269A (en) * 1992-06-18 1995-10-17 North Carolina State University 14-halo-camptothecins
FR2757514B1 (fr) * 1996-12-20 1999-02-12 Sod Conseils Rech Applic Nouveaux analogues de la camptothecine, des procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
EP1251125B1 (fr) * 1995-06-21 2005-12-07 Société de Conseils et de Recherches d'Applications Scientifiques (S.C.R.A.S.) Nouveaux analogues de la camptoth-cine, des proc-d-s de pr-paration, leur application comme m-dicaments et les compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
EP1007527B1 (fr) 2003-10-29
CZ297896B6 (cs) 2007-04-25
KR20010023394A (ko) 2001-03-26
TW419479B (en) 2001-01-21
EP1378512A1 (fr) 2004-01-07
HK1058665A1 (en) 2004-05-28
DE69819340T2 (de) 2004-08-19
WO1999011646A1 (fr) 1999-03-11
IL134437A (en) 2006-08-01
DE69819340D1 (de) 2003-12-04
KR100570254B1 (ko) 2006-04-12
ATE253069T1 (de) 2003-11-15
FR2768431B1 (fr) 2000-03-24
ES2209196T3 (es) 2004-06-16
NO324882B1 (no) 2007-12-27
NO20000995D0 (no) 2000-02-28
BR9811405A (pt) 2000-08-29
PT1007527E (pt) 2004-03-31
NO20000995L (no) 2000-02-28
AU8989698A (en) 1999-03-22
PL195289B1 (pl) 2007-08-31
AR016856A1 (es) 2001-08-01
CN1440973A (zh) 2003-09-10
HK1031732A1 (en) 2001-06-22
AU760863B2 (en) 2003-05-22
HUP0003429A1 (hu) 2001-07-30
JP2001514261A (ja) 2001-09-11
CZ2000711A3 (cs) 2000-08-16
CA2301739A1 (fr) 1999-03-11
IL134437A0 (en) 2001-04-30
HUP0003429A3 (en) 2002-11-28
CN1195758C (zh) 2005-04-06
FR2768431A1 (fr) 1999-03-19
NZ502862A (en) 2002-10-25
CN1440972A (zh) 2003-09-10
PL338835A1 (en) 2000-11-20
CA2301739C (fr) 2009-11-17
RU2233283C2 (ru) 2004-07-27
DK1007527T3 (da) 2004-03-08
CN1104434C (zh) 2003-04-02
HRP20000110A2 (en) 2001-02-28
EP1007527A1 (fr) 2000-06-14
CN1268948A (zh) 2000-10-04

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