IL134437A0 - Optically pure camptothecin analogues, optically pure synthesis intermediate and method for preparing same - Google Patents

Optically pure camptothecin analogues, optically pure synthesis intermediate and method for preparing same

Info

Publication number
IL134437A0
IL134437A0 IL13443798A IL13443798A IL134437A0 IL 134437 A0 IL134437 A0 IL 134437A0 IL 13443798 A IL13443798 A IL 13443798A IL 13443798 A IL13443798 A IL 13443798A IL 134437 A0 IL134437 A0 IL 134437A0
Authority
IL
Israel
Prior art keywords
optically pure
preparing same
synthesis intermediate
camptothecin analogues
analogues
Prior art date
Application number
IL13443798A
Other languages
English (en)
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of IL134437A0 publication Critical patent/IL134437A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL13443798A 1997-08-29 1998-08-07 Optically pure camptothecin analogues, optically pure synthesis intermediate and method for preparing same IL134437A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9710785A FR2768431B1 (fr) 1997-08-29 1997-08-29 Nouveaux analogues optiquement purs de la camptothecine, nouvel intermediaire de synthese optiquement pur et son procede de preparation
PCT/FR1998/001768 WO1999011646A1 (fr) 1997-08-29 1998-08-07 Analogues optiquement purs de la camptothecine, intermediaire de synthese optiquement pur et son procede de preparation

Publications (1)

Publication Number Publication Date
IL134437A0 true IL134437A0 (en) 2001-04-30

Family

ID=9510590

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13443798A IL134437A0 (en) 1997-08-29 1998-08-07 Optically pure camptothecin analogues, optically pure synthesis intermediate and method for preparing same
IL134437A IL134437A (en) 1997-08-29 2000-02-08 History of Homocompetition Pure optically

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL134437A IL134437A (en) 1997-08-29 2000-02-08 History of Homocompetition Pure optically

Country Status (25)

Country Link
EP (2) EP1007527B1 (cs)
JP (1) JP2001514261A (cs)
KR (1) KR100570254B1 (cs)
CN (3) CN1104434C (cs)
AR (1) AR016856A1 (cs)
AT (1) ATE253069T1 (cs)
AU (1) AU760863B2 (cs)
BR (1) BR9811405A (cs)
CA (1) CA2301739C (cs)
CZ (1) CZ297896B6 (cs)
DE (1) DE69819340T2 (cs)
DK (1) DK1007527T3 (cs)
ES (1) ES2209196T3 (cs)
FR (1) FR2768431B1 (cs)
HR (1) HRP20000110A2 (cs)
HU (1) HUP0003429A3 (cs)
IL (2) IL134437A0 (cs)
NO (1) NO324882B1 (cs)
NZ (1) NZ502862A (cs)
PL (1) PL195289B1 (cs)
PT (1) PT1007527E (cs)
RU (1) RU2233283C2 (cs)
TW (1) TW419479B (cs)
WO (1) WO1999011646A1 (cs)
ZA (1) ZA987445B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790261B1 (fr) * 1999-02-26 2004-09-10 Sod Conseils Rech Applic Nouveaux analogues optiquement purs de la camptothecine et leurs procedes de preparation
US6207832B1 (en) 1999-04-09 2001-03-27 University Of Pittsburgh Camptothecin analogs and methods of preparation thereof
US6372906B1 (en) 2001-04-12 2002-04-16 University Of Pittsburgh Synthesis of silyl camptothecins and silyl homocamptothecins
US6723853B2 (en) 2001-08-27 2004-04-20 University Of Pittsburgh Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins
CN100408582C (zh) * 2004-02-12 2008-08-06 中国人民解放军第二军医大学 高喜树碱类化合物及其制备方法和用途
EP1794127A1 (en) * 2004-09-21 2007-06-13 Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) Novel processes for the production of useful intermediates
CN100465175C (zh) * 2005-11-29 2009-03-04 中国人民解放军第二军医大学 7-位取代高喜树碱类化合物及作为药物的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3008226B2 (ja) * 1991-01-16 2000-02-14 第一製薬株式会社 六環性化合物
US5459269A (en) * 1992-06-18 1995-10-17 North Carolina State University 14-halo-camptothecins
FR2757514B1 (fr) * 1996-12-20 1999-02-12 Sod Conseils Rech Applic Nouveaux analogues de la camptothecine, des procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
ATE224900T1 (de) * 1995-06-21 2002-10-15 Sod Conseils Rech Applic Camptothecinanaloge, verfahren zur ihrer herstellung, ihre verwendungals arzneimittel und diese enthaltende pharmazeutische zusammenfassungen

Also Published As

Publication number Publication date
AU8989698A (en) 1999-03-22
IL134437A (en) 2006-08-01
PL195289B1 (pl) 2007-08-31
CN1440972A (zh) 2003-09-10
PL338835A1 (en) 2000-11-20
TW419479B (en) 2001-01-21
HK1058665A1 (en) 2004-05-28
ZA987445B (en) 1999-02-17
BR9811405A (pt) 2000-08-29
HUP0003429A3 (en) 2002-11-28
JP2001514261A (ja) 2001-09-11
ATE253069T1 (de) 2003-11-15
CA2301739A1 (fr) 1999-03-11
EP1007527B1 (fr) 2003-10-29
AU760863B2 (en) 2003-05-22
CN1104434C (zh) 2003-04-02
EP1378512A1 (fr) 2004-01-07
NO20000995D0 (no) 2000-02-28
DK1007527T3 (da) 2004-03-08
CN1440973A (zh) 2003-09-10
ES2209196T3 (es) 2004-06-16
HRP20000110A2 (en) 2001-02-28
NO20000995L (no) 2000-02-28
DE69819340D1 (de) 2003-12-04
CN1195758C (zh) 2005-04-06
FR2768431B1 (fr) 2000-03-24
HUP0003429A1 (hu) 2001-07-30
NZ502862A (en) 2002-10-25
DE69819340T2 (de) 2004-08-19
KR100570254B1 (ko) 2006-04-12
PT1007527E (pt) 2004-03-31
FR2768431A1 (fr) 1999-03-19
NO324882B1 (no) 2007-12-27
RU2233283C2 (ru) 2004-07-27
CA2301739C (fr) 2009-11-17
CZ2000711A3 (cs) 2000-08-16
KR20010023394A (ko) 2001-03-26
EP1007527A1 (fr) 2000-06-14
CN1268948A (zh) 2000-10-04
WO1999011646A1 (fr) 1999-03-11
CZ297896B6 (cs) 2007-04-25
AR016856A1 (es) 2001-08-01
HK1031732A1 (en) 2001-06-22

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