ZA986475B - Thermodynamically stable modification of 1-(4-carbazoly loxy)3-[2-)2-methoxyphenoxy)ethylamino]-2-propanole, and pharmaceutical compositions containing it. - Google Patents

Thermodynamically stable modification of 1-(4-carbazoly loxy)3-[2-)2-methoxyphenoxy)ethylamino]-2-propanole, and pharmaceutical compositions containing it.

Info

Publication number
ZA986475B
ZA986475B ZA9806475A ZA986475A ZA986475B ZA 986475 B ZA986475 B ZA 986475B ZA 9806475 A ZA9806475 A ZA 9806475A ZA 986475 A ZA986475 A ZA 986475A ZA 986475 B ZA986475 B ZA 986475B
Authority
ZA
South Africa
Prior art keywords
carbazoly
propanole
loxy
methoxyphenoxy
ethylamino
Prior art date
Application number
ZA9806475A
Other languages
English (en)
Inventor
Erhard Reinholz
Peter Beyer
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of ZA986475B publication Critical patent/ZA986475B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
ZA9806475A 1997-07-22 1998-07-21 Thermodynamically stable modification of 1-(4-carbazoly loxy)3-[2-)2-methoxyphenoxy)ethylamino]-2-propanole, and pharmaceutical compositions containing it. ZA986475B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97112491A EP0893440A1 (en) 1997-07-22 1997-07-22 Thermodynamically stable modification of 1-(4-carbazolyloxy)-3-[2-(2-methoxyphenoxy)ethylamino]-2-propanole, process for its preparation and pharmaceutical compositions containing it

Publications (1)

Publication Number Publication Date
ZA986475B true ZA986475B (en) 2000-01-21

Family

ID=8227094

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9806475A ZA986475B (en) 1997-07-22 1998-07-21 Thermodynamically stable modification of 1-(4-carbazoly loxy)3-[2-)2-methoxyphenoxy)ethylamino]-2-propanole, and pharmaceutical compositions containing it.

Country Status (31)

Country Link
EP (2) EP0893440A1 (cs)
JP (1) JP2001510824A (cs)
KR (1) KR100336229B1 (cs)
CN (1) CN1125047C (cs)
AR (1) AR015133A1 (cs)
AT (1) ATE236123T1 (cs)
AU (1) AU740453B2 (cs)
BR (1) BR9810776A (cs)
CA (1) CA2296637C (cs)
CZ (1) CZ296947B6 (cs)
DE (1) DE69812964T2 (cs)
DK (1) DK1000027T3 (cs)
ES (1) ES2195366T3 (cs)
HR (1) HRP980406A2 (cs)
HU (1) HUP0003198A3 (cs)
IL (1) IL133677A (cs)
MA (1) MA26523A1 (cs)
MY (1) MY117734A (cs)
NO (1) NO313588B1 (cs)
NZ (1) NZ502136A (cs)
PE (1) PE96999A1 (cs)
PL (1) PL191602B1 (cs)
PT (1) PT1000027E (cs)
RU (1) RU2202542C2 (cs)
SI (1) SI1000027T1 (cs)
TR (1) TR200000148T2 (cs)
TW (1) TW505631B (cs)
UY (1) UY25108A1 (cs)
WO (1) WO1999005105A1 (cs)
YU (1) YU2200A (cs)
ZA (1) ZA986475B (cs)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003528914A (ja) * 2000-04-03 2003-09-30 エフ．ホフマン−ラ ロシュ アーゲー カルベジロールの濃縮溶液
KR20030017569A (ko) 2000-06-28 2003-03-03 테바 파마슈티컬 인더스트리즈 리미티드 카르베딜올
EP1655285A1 (en) * 2000-06-28 2006-05-10 Teva Pharmaceutical Industries Ltd. Method for preparation of a crystalline form of carvedilol (form II)
AU2002326391A1 (en) * 2001-07-13 2003-01-29 Smithkline Beecham Corporation Carvedilol polymorph
US20050019399A1 (en) 2001-09-21 2005-01-27 Gina Fischer Controlled release solid dispersions
JP2005507899A (ja) * 2001-09-28 2005-03-24 エフ．ホフマン−ラ　ロシュ　アーゲー カルベジロールの疑似多形形態
KR20040077872A (ko) 2002-01-15 2004-09-07 테바 파마슈티컬 인더스트리즈 리미티드 카베디롤의 결정질 고체 및 그 제조 방법
CA2483054A1 (en) * 2002-04-30 2003-11-13 Sb Pharmco Puerto Rico Inc. Carvedilol monocitrate monohydrate
CN101898995B (zh) * 2002-06-27 2013-05-01 史密斯克莱·比奇曼（科克）有限公司 卡维地洛磷酸盐和/或其溶剂合物相应的组合物和/或治疗方法
CA2492084A1 (en) * 2002-06-27 2004-01-08 Sb Pharmco Puerto Rico Inc. Carvedilol hydobromide
EP1562552A1 (en) * 2002-11-08 2005-08-17 Egalet A/S Controlled release carvedilol compositions
DE602004031096D1 (de) 2003-03-26 2011-03-03 Egalet As Morphin-system mit kontrollierter freisetzung
EP1615888A1 (en) 2003-04-21 2006-01-18 Matrix Laboratories Ltd Process for the preparation of carvedilol form-ii
SI21616A (sl) * 2003-09-02 2005-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove kristalne oblike karvedilola
WO2005051383A1 (en) * 2003-11-25 2005-06-09 Sb Pharmco Puerto Rico Inc. Carvedilol salts, corresponding compositions, methods of delivery and/or treatment
CA2589699A1 (en) * 2004-12-09 2006-06-15 Zach System S.P.A. Process for the preparation of carvedilol and its enantiomers
KR20070088507A (ko) * 2005-06-09 2007-08-29 테바 파마슈티컬 인더스트리즈 리미티드 카베딜올의 결정질 형태 및 이것의 제조 방법
EP1991527A2 (en) 2006-06-28 2008-11-19 Teva Pharmaceutical Industries Ltd Polymorphous forms of carvedilol phosphate
RU2366653C2 (ru) * 2006-07-03 2009-09-10 Ооо "Нанокриохимия" Способ получения рентгеноаморфной модификации карведилола
US20080249317A1 (en) * 2007-04-04 2008-10-09 Apotex Inc. Novel amorphous form of carvedilol phosphate and processes for the preparation thereof
NZ580972A (en) 2007-06-04 2012-02-24 Egalet Ltd Controlled release pharmaceutical compositions for prolonged effect
AU2010211220B2 (en) 2009-02-06 2013-08-01 Egalet Ltd. Immediate release composition resistant to abuse by intake of alcohol
CA2766179A1 (en) 2009-06-24 2010-12-29 Egalet Ltd. Controlled release formulations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2815926A1 (de) * 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2805404A1 (de) * 1978-02-09 1979-08-16 Merck Patent Gmbh 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung
DE3319027A1 (de) * 1983-05-26 1984-11-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten

Also Published As

Publication number Publication date
NZ502136A (en) 2002-05-31
CN1125047C (zh) 2003-10-22
PT1000027E (pt) 2003-07-31
UY25108A1 (es) 2000-12-29
IL133677A0 (en) 2001-04-30
AU740453B2 (en) 2001-11-01
EP1000027A1 (en) 2000-05-17
DE69812964T2 (de) 2004-03-04
NO20000301D0 (no) 2000-01-21
WO1999005105A1 (en) 1999-02-04
HK1029339A1 (en) 2001-03-30
PL191602B1 (pl) 2006-06-30
AU8631998A (en) 1999-02-16
BR9810776A (pt) 2000-09-19
KR100336229B1 (ko) 2002-05-09
TR200000148T2 (tr) 2000-07-21
CA2296637C (en) 2005-11-15
ES2195366T3 (es) 2003-12-01
CZ296947B6 (cs) 2006-08-16
PE96999A1 (es) 1999-10-12
ATE236123T1 (de) 2003-04-15
PL338432A1 (en) 2000-11-06
CN1264366A (zh) 2000-08-23
RU2202542C2 (ru) 2003-04-20
EP1000027B1 (en) 2003-04-02
TW505631B (en) 2002-10-11
MA26523A1 (fr) 2004-12-20
DE69812964D1 (de) 2003-05-08
SI1000027T1 (en) 2003-10-31
YU2200A (sh) 2002-03-18
CZ2000221A3 (cs) 2000-05-17
NO20000301L (no) 2000-01-21
HRP980406A2 (en) 1999-04-30
JP2001510824A (ja) 2001-08-07
CA2296637A1 (en) 1999-02-04
EP0893440A1 (en) 1999-01-27
KR20010022097A (ko) 2001-03-15
HUP0003198A3 (en) 2002-10-28
HUP0003198A2 (en) 2001-03-28
IL133677A (en) 2004-06-01
NO313588B1 (no) 2002-10-28
AR015133A1 (es) 2001-04-18
MY117734A (en) 2004-07-31
DK1000027T3 (da) 2003-07-21

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