ZA985656B - 2-Substituted 4,5-diaryl imidazoles - Google Patents

2-Substituted 4,5-diaryl imidazoles

Info

Publication number
ZA985656B
ZA985656B ZA985656A ZA985656A ZA985656B ZA 985656 B ZA985656 B ZA 985656B ZA 985656 A ZA985656 A ZA 985656A ZA 985656 A ZA985656 A ZA 985656A ZA 985656 B ZA985656 B ZA 985656B
Authority
ZA
South Africa
Prior art keywords
substituted
diaryl
imidazoles
diaryl imidazoles
Prior art date
Application number
ZA985656A
Other languages
English (en)
Inventor
Laszlo Revesz
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ZA985656B publication Critical patent/ZA985656B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
ZA985656A 1997-06-30 1998-06-29 2-Substituted 4,5-diaryl imidazoles ZA985656B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9713726.9A GB9713726D0 (en) 1997-06-30 1997-06-30 Organic compounds

Publications (1)

Publication Number Publication Date
ZA985656B true ZA985656B (en) 1998-12-30

Family

ID=10815101

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA985656A ZA985656B (en) 1997-06-30 1998-06-29 2-Substituted 4,5-diaryl imidazoles

Country Status (28)

Country Link
US (1) US6300347B1 (es)
EP (2) EP0993456B1 (es)
JP (1) JP3704362B2 (es)
KR (1) KR20010013215A (es)
CN (1) CN1261885A (es)
AR (1) AR014886A1 (es)
AT (1) ATE275557T1 (es)
AU (1) AU744411B2 (es)
BR (1) BR9810955A (es)
CA (1) CA2291758A1 (es)
CO (1) CO4940462A1 (es)
DE (1) DE69826127T2 (es)
ES (1) ES2226164T3 (es)
GB (1) GB9713726D0 (es)
HU (1) HUP0003351A3 (es)
ID (1) ID23385A (es)
IL (1) IL133034A0 (es)
NO (1) NO996429L (es)
NZ (1) NZ501275A (es)
PE (1) PE99999A1 (es)
PL (1) PL337057A1 (es)
PT (1) PT993456E (es)
RU (1) RU2214408C2 (es)
SK (1) SK186599A3 (es)
TR (1) TR199903278T2 (es)
TW (1) TW429258B (es)
WO (1) WO1999001449A1 (es)
ZA (1) ZA985656B (es)

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DE60041763D1 (de) * 1999-04-23 2009-04-23 Vertex Pharma Inhibitoren von c-jun n-terminal kinasen (jnk)
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US7344716B2 (en) * 2003-05-13 2008-03-18 Depuy Spine, Inc. Transdiscal administration of specific inhibitors of pro-inflammatory cytokines
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Also Published As

Publication number Publication date
US6300347B1 (en) 2001-10-09
ID23385A (id) 2000-04-20
PE99999A1 (es) 1999-11-01
GB9713726D0 (en) 1997-09-03
AU8801598A (en) 1999-01-25
EP1396491A2 (en) 2004-03-10
EP1396491A3 (en) 2004-06-30
KR20010013215A (ko) 2001-02-26
NO996429D0 (no) 1999-12-23
CO4940462A1 (es) 2000-07-24
DE69826127D1 (de) 2004-10-14
CN1261885A (zh) 2000-08-02
RU2214408C2 (ru) 2003-10-20
NO996429L (no) 1999-12-23
PL337057A1 (en) 2000-07-31
TR199903278T2 (en) 2000-07-21
EP0993456B1 (en) 2004-09-08
ES2226164T3 (es) 2005-03-16
AR014886A1 (es) 2001-04-11
ATE275557T1 (de) 2004-09-15
TW429258B (en) 2001-04-11
CA2291758A1 (en) 1999-01-14
PT993456E (pt) 2005-01-31
IL133034A0 (en) 2001-03-19
SK186599A3 (en) 2000-06-12
BR9810955A (pt) 2000-09-26
JP3704362B2 (ja) 2005-10-12
HUP0003351A3 (en) 2002-01-28
DE69826127T2 (de) 2005-09-29
EP0993456A1 (en) 2000-04-19
JP2001506280A (ja) 2001-05-15
WO1999001449A1 (en) 1999-01-14
AU744411B2 (en) 2002-02-21
NZ501275A (en) 2002-04-26
HUP0003351A2 (hu) 2001-06-28

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