ZA978560B - Pictet-Spengler reaction for the synthesis of tetrahydroisoquinolines and related heterocyclic compounds. - Google Patents

Pictet-Spengler reaction for the synthesis of tetrahydroisoquinolines and related heterocyclic compounds.

Info

Publication number
ZA978560B
ZA978560B ZA9708560A ZA978560A ZA978560B ZA 978560 B ZA978560 B ZA 978560B ZA 9708560 A ZA9708560 A ZA 9708560A ZA 978560 A ZA978560 A ZA 978560A ZA 978560 B ZA978560 B ZA 978560B
Authority
ZA
South Africa
Prior art keywords
tetrahydroisoquinolines
pictet
synthesis
heterocyclic compounds
related heterocyclic
Prior art date
Application number
ZA9708560A
Other languages
English (en)
Inventor
Timothy James-Norman Watson
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of ZA978560B publication Critical patent/ZA978560B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • C07D217/20Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA9708560A 1996-09-27 1997-09-23 Pictet-Spengler reaction for the synthesis of tetrahydroisoquinolines and related heterocyclic compounds. ZA978560B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72258896A 1996-09-27 1996-09-27

Publications (1)

Publication Number Publication Date
ZA978560B true ZA978560B (en) 1998-03-27

Family

ID=24902494

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9708560A ZA978560B (en) 1996-09-27 1997-09-23 Pictet-Spengler reaction for the synthesis of tetrahydroisoquinolines and related heterocyclic compounds.

Country Status (22)

Country Link
EP (1) EP0929527B1 (he)
JP (1) JP2001510449A (he)
KR (1) KR100445953B1 (he)
CN (1) CN1101811C (he)
AR (1) AR009364A1 (he)
AT (1) ATE280761T1 (he)
AU (1) AU711358B2 (he)
BR (1) BR9712143B1 (he)
CA (1) CA2266357C (he)
DE (1) DE69731392T2 (he)
DK (1) DK0929527T3 (he)
ES (1) ES2230618T3 (he)
HK (1) HK1022311A1 (he)
HU (1) HUP9904161A3 (he)
IL (1) IL129188A (he)
NO (1) NO312761B1 (he)
NZ (1) NZ334491A (he)
PT (1) PT929527E (he)
SI (1) SI0929527T1 (he)
TW (1) TW434224B (he)
WO (1) WO1998013351A1 (he)
ZA (1) ZA978560B (he)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100503571C (zh) * 2006-07-12 2009-06-24 中国药科大学 四氢异喹啉类衍生物、其制备方法及其医药用途
EP2420237A1 (en) 2010-08-11 2012-02-22 Ville Takio Fluorinated derivatives of endogenous isoquinolines for use in the treatment of diseases mediated through endogenous isoquinoline pathways
CN103694170B (zh) * 2013-04-01 2016-04-06 常州夏青化工有限公司 6,7-二氟-1-甲基-1,2,3,4-四氢异喹啉盐酸盐的合成方法
CN110590795B (zh) * 2019-10-10 2021-01-22 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 一类多并杂环螺羟吲哚类化合物的合成方法
FI130627B (en) 2021-03-31 2023-12-18 Equinorm Ltd NEW HETEROCYCLIC COMPOUNDS AND THEIR USE
CN113214252B (zh) * 2021-05-28 2022-02-11 常州大学 6-苯基-7-(吡啶-2-基)-7H-吲哚并[2,3-c]喹啉化合物的合成方法

Also Published As

Publication number Publication date
NO991495D0 (no) 1999-03-26
CA2266357C (en) 2003-07-29
BR9712143A (pt) 1999-08-31
AR009364A1 (es) 2000-04-12
BR9712143B1 (pt) 2009-05-05
EP0929527B1 (en) 2004-10-27
EP0929527A1 (en) 1999-07-21
CN1231660A (zh) 1999-10-13
HUP9904161A2 (hu) 2000-05-28
NZ334491A (en) 2000-04-28
JP2001510449A (ja) 2001-07-31
DE69731392D1 (de) 2004-12-02
CA2266357A1 (en) 1998-04-02
AU3906397A (en) 1998-04-17
ES2230618T3 (es) 2005-05-01
IL129188A (he) 2004-03-28
DK0929527T3 (da) 2005-02-14
HK1022311A1 (en) 2000-08-04
NO991495L (no) 1999-03-26
WO1998013351A1 (en) 1998-04-02
KR100445953B1 (ko) 2004-08-25
CN1101811C (zh) 2003-02-19
ATE280761T1 (de) 2004-11-15
DE69731392T2 (de) 2006-02-09
IL129188A0 (en) 2000-02-17
KR20000048638A (ko) 2000-07-25
TW434224B (en) 2001-05-16
NO312761B1 (no) 2002-07-01
SI0929527T1 (en) 2005-02-28
AU711358B2 (en) 1999-10-14
PT929527E (pt) 2005-01-31
HUP9904161A3 (en) 2001-01-29

Similar Documents

Publication Publication Date Title
GB9602294D0 (en) Heterocyclic compounds
AU2871195A (en) Methods for the synthesis of diketopiperazines
GB9617305D0 (en) Heterocyclic compounds
IL126272A0 (en) Synthesis of indolylmaleimides
ZA988455B (en) Method for the synthesis of quinoline derivatives
IL128376A0 (en) Synthesis of bisindolylmalimides
ZA978560B (en) Pictet-Spengler reaction for the synthesis of tetrahydroisoquinolines and related heterocyclic compounds.
IL129868A0 (en) Process for the synthesis of benzothiopenes
HU9603524D0 (en) 1-amino-3-(bicyclic heterocyclic)-6-fluorine-alkyl-uracil derivatives
HU9700273D0 (en) Tetrahydroisoquinoline derivatives
ZA979066B (en) Process for the synthesis of β-ketonitriles.
EP0900204A4 (en) HETEROCYCLIC CONNECTIONS
HUP0103105A3 (en) Process for the synthesis of exochelins
EG21037A (en) Process for the synthesis of benzathiophenes
EP0923519A4 (en) PRODUCTION OF HALOALKYNOLS
EP0912183A4 (en) HETEROCYCLIC COMPOSITIONS
EP0900219A4 (en) HETEROCYCLIC COMPOUNDS
EP0900217A4 (en) HETEROCYCLIC COMPOUNDS
GB9613026D0 (en) Heterocyclic compounds
GB9617306D0 (en) Heterocyclic compounds
GB9625495D0 (en) Heterocyclic compounds
ZA976147B (en) Heterocyclic compounds
ZA976146B (en) Heterocyclic compounds
ZA976145B (en) Heterocyclic compounds
GB9626856D0 (en) Heterocyclic compounds