ZA975312B - Ortho-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them. - Google Patents

Ortho-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them.

Info

Publication number
ZA975312B
ZA975312B ZA9705312A ZA975312A ZA975312B ZA 975312 B ZA975312 B ZA 975312B ZA 9705312 A ZA9705312 A ZA 9705312A ZA 975312 A ZA975312 A ZA 975312A ZA 975312 B ZA975312 B ZA 975312B
Authority
ZA
South Africa
Prior art keywords
medicament
ortho
diagnostic
preparation
substituted benzoylguanidines
Prior art date
Application number
ZA9705312A
Other languages
English (en)
Inventor
Andreas Weichert
Joachim Brendel
Heinz-Werner Kleemann
Hans Jochen Lang
Jan-Robert Schwark
Udo Albus
Wolfgang Scholz
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA975312B publication Critical patent/ZA975312B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
ZA9705312A 1996-06-18 1997-06-17 Ortho-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them. ZA975312B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19624178A DE19624178A1 (de) 1996-06-18 1996-06-18 Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (1)

Publication Number Publication Date
ZA975312B true ZA975312B (en) 1998-01-05

Family

ID=7797197

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9705312A ZA975312B (en) 1996-06-18 1997-06-17 Ortho-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them.

Country Status (31)

Country Link
US (1) US6001881A (no)
EP (1) EP0814077B1 (no)
JP (1) JP3977897B2 (no)
KR (1) KR100498799B1 (no)
CN (1) CN1064676C (no)
AR (1) AR012536A1 (no)
AT (1) ATE191469T1 (no)
AU (1) AU711734B2 (no)
BR (1) BR9703617A (no)
CA (1) CA2207886A1 (no)
CZ (1) CZ291848B6 (no)
DE (2) DE19624178A1 (no)
DK (1) DK0814077T3 (no)
ES (1) ES2146049T3 (no)
GR (1) GR3033299T3 (no)
HR (1) HRP970332B1 (no)
HU (1) HUP9701057A3 (no)
ID (1) ID17321A (no)
IL (1) IL121085A0 (no)
MX (1) MX9704486A (no)
MY (1) MY117304A (no)
NO (1) NO307928B1 (no)
NZ (1) NZ328100A (no)
PL (1) PL185756B1 (no)
PT (1) PT814077E (no)
RU (1) RU2193025C2 (no)
SI (1) SI0814077T1 (no)
SK (1) SK282351B6 (no)
TR (1) TR199700508A2 (no)
TW (1) TW374759B (no)
ZA (1) ZA975312B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19608161A1 (de) * 1996-03-04 1997-09-11 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19713427A1 (de) * 1997-04-01 1998-10-08 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE10001879A1 (de) * 2000-01-19 2001-07-19 Aventis Pharma Gmbh Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
US6641811B1 (en) * 2000-02-10 2003-11-04 Cornell Research Foundation, Inc. Use of angiotensin II inhibitors to prevent malignancies associated with immunosuppression
US7828840B2 (en) * 2007-11-15 2010-11-09 Med Institute, Inc. Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4318756A1 (de) * 1993-06-05 1994-12-08 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4430213A1 (de) * 1994-08-28 1996-02-29 Merck Patent Gmbh Arylbenzoylguanidine
DE4430916A1 (de) * 1994-08-31 1996-03-07 Merck Patent Gmbh Alkyl-benzoylguanidin-Derivate
DE4430861A1 (de) * 1994-08-31 1996-03-07 Merck Patent Gmbh Heterocyclyl-benzoylguanidine
DE19608162A1 (de) * 1996-03-04 1997-09-11 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
CA2207886A1 (en) 1997-12-18
ES2146049T3 (es) 2000-07-16
EP0814077A1 (de) 1997-12-29
KR980002020A (ko) 1998-03-30
PL320326A1 (en) 1997-12-22
MX9704486A (es) 1997-12-31
ATE191469T1 (de) 2000-04-15
EP0814077B1 (de) 2000-04-05
KR100498799B1 (ko) 2005-12-16
CN1064676C (zh) 2001-04-18
GR3033299T3 (en) 2000-09-29
NO307928B1 (no) 2000-06-19
MY117304A (en) 2004-06-30
JPH1067733A (ja) 1998-03-10
RU2193025C2 (ru) 2002-11-20
HUP9701057A2 (hu) 1998-12-28
CZ291848B6 (cs) 2003-06-18
PT814077E (pt) 2000-07-31
JP3977897B2 (ja) 2007-09-19
HUP9701057A3 (en) 2000-08-28
SI0814077T1 (en) 2000-08-31
SK76697A3 (en) 1998-01-14
NZ328100A (en) 1998-09-24
DE59701388D1 (de) 2000-05-11
TR199700508A2 (xx) 1998-01-21
HRP970332A2 (en) 1998-04-30
PL185756B1 (pl) 2003-07-31
SK282351B6 (sk) 2002-01-07
CN1169987A (zh) 1998-01-14
IL121085A0 (en) 1997-11-20
CZ188797A3 (cs) 1998-05-13
AU2494297A (en) 1998-01-08
TW374759B (en) 1999-11-21
HU9701057D0 (en) 1997-08-28
NO972793L (no) 1997-12-19
US6001881A (en) 1999-12-14
NO972793D0 (no) 1997-06-17
AR012536A1 (es) 2000-11-08
ID17321A (id) 1997-12-18
BR9703617A (pt) 1998-09-29
DE19624178A1 (de) 1998-01-08
AU711734B2 (en) 1999-10-21
DK0814077T3 (da) 2000-08-14
HRP970332B1 (en) 2001-02-28

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