ZA971184B - Endothelin antagonists. - Google Patents

Endothelin antagonists.

Info

Publication number
ZA971184B
ZA971184B ZA9701184A ZA971184A ZA971184B ZA 971184 B ZA971184 B ZA 971184B ZA 9701184 A ZA9701184 A ZA 9701184A ZA 971184 A ZA971184 A ZA 971184A ZA 971184 B ZA971184 B ZA 971184B
Authority
ZA
South Africa
Prior art keywords
endothelin antagonists
endothelin
antagonists
Prior art date
Application number
ZA9701184A
Other languages
English (en)
Inventor
Andrew S Tasker
Thomas W Vongeldern
Hwan-Soo Jae
Bryan K Sorensen
Martin Winn
Steven A Boyd
Kenneth J Henry
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of ZA971184B publication Critical patent/ZA971184B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9701184A 1996-02-13 1997-02-12 Endothelin antagonists. ZA971184B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60072496A 1996-02-13 1996-02-13
US79450597A 1997-02-04 1997-02-04

Publications (1)

Publication Number Publication Date
ZA971184B true ZA971184B (en) 1997-08-27

Family

ID=27083691

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9701184A ZA971184B (en) 1996-02-13 1997-02-12 Endothelin antagonists.

Country Status (18)

Country Link
EP (1) EP0888340B1 (fr)
JP (1) JP2000504727A (fr)
CN (1) CN1079397C (fr)
AR (1) AR005801A1 (fr)
AT (1) ATE220673T1 (fr)
AU (1) AU714597B2 (fr)
BR (1) BR9707394A (fr)
CA (1) CA2245684A1 (fr)
CZ (1) CZ253698A3 (fr)
DE (1) DE69714024T2 (fr)
DK (1) DK0888340T3 (fr)
ES (1) ES2182029T3 (fr)
HU (1) HUP9902316A3 (fr)
IL (1) IL125453A0 (fr)
NZ (2) NZ331124A (fr)
PT (1) PT888340E (fr)
WO (1) WO1997030046A1 (fr)
ZA (1) ZA971184B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7208517B1 (en) 1994-08-19 2007-04-24 Abbott Labortories Endothelin antagonists
US6162927A (en) 1994-08-19 2000-12-19 Abbott Laboratories Endothelin antagonists
US6124341A (en) * 1996-02-13 2000-09-26 Abbott Laboratories Endothelin antagonists
AU7826398A (en) * 1997-06-17 1999-01-04 Abbott Laboratories Pyrrolidine carboxylic acid derivatives as endothelin antagonists
CN1301264A (zh) * 1997-08-04 2001-06-27 艾博特公司 内皮素拮抗剂
JP3983663B2 (ja) * 2000-07-19 2007-09-26 エフ．ホフマン−ラ ロシュ アーゲー メタロプロテアーゼインヒビターとしてのピロリジン誘導体
WO2002017912A1 (fr) * 2000-08-31 2002-03-07 Abbott Laboratories Antagonistes de l'endotheline
RU2259825C9 (ru) * 2001-06-18 2006-04-10 БиоДием Лимитед Вещества, проявляющие антимикробную, антигрибковую, антипротозойную активности

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2125980C1 (ru) * 1991-11-05 1999-02-10 Смитклайн Бичам Корпорейшн Антагонисты эндотелиновых рецепторов, фармкомпозиция, способ их получения, способ подавления эндотелиновых рецепторов
AU4679793A (en) * 1992-07-17 1994-02-14 Smithkline Beecham Corporation Endothelin receptor antagonists
EP1186603A3 (fr) * 1994-08-19 2003-07-09 Abbott Laboratories Procédés de préparation d'antagonistes de l'endotheline

Also Published As

Publication number Publication date
ES2182029T3 (es) 2003-03-01
DE69714024D1 (de) 2002-08-22
BR9707394A (pt) 1999-04-06
CZ253698A3 (cs) 1999-03-17
AU714597B2 (en) 2000-01-06
HUP9902316A2 (hu) 1999-11-29
CN1079397C (zh) 2002-02-20
ATE220673T1 (de) 2002-08-15
AU2267897A (en) 1997-09-02
AR005801A1 (es) 1999-07-14
DK0888340T3 (da) 2002-11-04
NZ331124A (en) 2000-05-26
NZ503383A (en) 2002-02-01
JP2000504727A (ja) 2000-04-18
CN1215401A (zh) 1999-04-28
IL125453A0 (en) 1999-03-12
EP0888340A1 (fr) 1999-01-07
EP0888340B1 (fr) 2002-07-17
CA2245684A1 (fr) 1997-08-21
PT888340E (pt) 2002-12-31
HUP9902316A3 (en) 2001-12-28
DE69714024T2 (de) 2003-03-20
WO1997030046A1 (fr) 1997-08-21

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