ZA985209B - Endothelin antagonists - Google Patents

Endothelin antagonists

Info

Publication number
ZA985209B
ZA985209B ZA985209A ZA985209A ZA985209B ZA 985209 B ZA985209 B ZA 985209B ZA 985209 A ZA985209 A ZA 985209A ZA 985209 A ZA985209 A ZA 985209A ZA 985209 B ZA985209 B ZA 985209B
Authority
ZA
South Africa
Prior art keywords
endothelin antagonists
endothelin
antagonists
Prior art date
Application number
ZA985209A
Inventor
Andrew S Tasker
Martin Winn
Steven A Boyd
Hwan-Soo Jae
Thomas W Vongeldern
Bryan K Sorensen
Kenneth J Henry
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of ZA985209B publication Critical patent/ZA985209B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA985209A 1997-06-17 1998-06-15 Endothelin antagonists ZA985209B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87718797A 1997-06-17 1997-06-17

Publications (1)

Publication Number Publication Date
ZA985209B true ZA985209B (en) 1999-01-06

Family

ID=25369437

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA985209A ZA985209B (en) 1997-06-17 1998-06-15 Endothelin antagonists

Country Status (8)

Country Link
AR (1) AR016071A1 (en)
AU (1) AU7826398A (en)
BG (1) BG103986A (en)
HU (1) HUP0002681A3 (en)
NO (1) NO996244L (en)
PL (1) PL348667A1 (en)
WO (1) WO1998057933A1 (en)
ZA (1) ZA985209B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7291626B1 (en) 1998-04-09 2007-11-06 John Hopkins University School Of Medicine Inhibitors of hedgehog signaling pathways, compositions and uses related thereto
JP5420128B2 (en) 1999-10-13 2014-02-19 ジョンズ ホプキンス ユニバーシティ スクール オブ メディシン Hedgehog pathway modulators and related compositions and methods of use
ATE324876T1 (en) * 1999-10-14 2006-06-15 Curis Inc AGENTS OF ßHEDGEHOGß TRANSMITTING RAILWAYS, ASSOCIATED INTERLINGS AND USE
US6552016B1 (en) 1999-10-14 2003-04-22 Curis, Inc. Mediators of hedgehog signaling pathways, compositions and uses related thereto
AR044510A1 (en) * 2003-04-14 2005-09-14 Merck & Co Inc PROCEDURE AND INTERMEDIATES TO PREPARE CARBOXILIC ACIDS OF PIRROLIDINE
CN114507143A (en) * 2022-02-26 2022-05-17 江苏壹药新材料有限公司 Synthesis method of 2-ethyl-1-fluoro-4-nitrobenzene

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1186603A3 (en) * 1994-08-19 2003-07-09 Abbott Laboratories Processes for preparing endothelin antagonists
HUP9902316A3 (en) * 1996-02-13 2001-12-28 Abbott Lab 4-(benzo-1,3-dioxolyl)-pyrrolidine-3-carboxylic acid derivatives as endothelin antagonists and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
AU7826398A (en) 1999-01-04
HUP0002681A2 (en) 2001-08-28
NO996244D0 (en) 1999-12-16
WO1998057933A1 (en) 1998-12-23
HUP0002681A3 (en) 2001-09-28
AR016071A1 (en) 2001-06-20
NO996244L (en) 2000-01-12
BG103986A (en) 2000-08-31
PL348667A1 (en) 2002-06-03

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