PL348667A1 - Pyrrolidine carboxylic acid derivatives as endothelin antagonists - Google Patents
Pyrrolidine carboxylic acid derivatives as endothelin antagonistsInfo
- Publication number
- PL348667A1 PL348667A1 PL98348667A PL34866798A PL348667A1 PL 348667 A1 PL348667 A1 PL 348667A1 PL 98348667 A PL98348667 A PL 98348667A PL 34866798 A PL34866798 A PL 34866798A PL 348667 A1 PL348667 A1 PL 348667A1
- Authority
- PL
- Poland
- Prior art keywords
- carboxylic acid
- acid derivatives
- endothelin antagonists
- pyrrolidine carboxylic
- pyrrolidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87718797A | 1997-06-17 | 1997-06-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL348667A1 true PL348667A1 (en) | 2002-06-03 |
Family
ID=25369437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL98348667A PL348667A1 (en) | 1997-06-17 | 1998-06-08 | Pyrrolidine carboxylic acid derivatives as endothelin antagonists |
Country Status (8)
| Country | Link |
|---|---|
| AR (1) | AR016071A1 (en) |
| AU (1) | AU7826398A (en) |
| BG (1) | BG103986A (en) |
| HU (1) | HUP0002681A3 (en) |
| NO (1) | NO996244L (en) |
| PL (1) | PL348667A1 (en) |
| WO (1) | WO1998057933A1 (en) |
| ZA (1) | ZA985209B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7291626B1 (en) | 1998-04-09 | 2007-11-06 | John Hopkins University School Of Medicine | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto |
| EP1728797A3 (en) | 1999-10-13 | 2011-03-02 | Johns Hopkins University School of Medicine | Regulators of the hedgehog pathway, compositions and uses related thereto |
| EP1227805B2 (en) * | 1999-10-14 | 2011-02-23 | Curis, Inc. | Mediators of hedgehog signaling pathways, compositions and uses related thereto |
| US6552016B1 (en) | 1999-10-14 | 2003-04-22 | Curis, Inc. | Mediators of hedgehog signaling pathways, compositions and uses related thereto |
| AR044510A1 (en) * | 2003-04-14 | 2005-09-14 | Merck & Co Inc | PROCEDURE AND INTERMEDIATES TO PREPARE CARBOXILIC ACIDS OF PIRROLIDINE |
| CN114507143A (en) * | 2022-02-26 | 2022-05-17 | 江苏壹药新材料有限公司 | Synthesis method of 2-ethyl-1-fluoro-4-nitrobenzene |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69527072T2 (en) * | 1994-08-19 | 2003-02-13 | Abbott Laboratories, Abbott Park | ENDOTHELIN ANTAGONISTE |
| AU714597B2 (en) * | 1996-02-13 | 2000-01-06 | Abbott Laboratories | 4-(benzo-1,3-dioxolyl)-pyrrolidine-3-carboxylic acid derivatives as endothelin antagonists |
-
1998
- 1998-06-08 HU HU0002681A patent/HUP0002681A3/en unknown
- 1998-06-08 AU AU78263/98A patent/AU7826398A/en not_active Abandoned
- 1998-06-08 PL PL98348667A patent/PL348667A1/en unknown
- 1998-06-08 WO PCT/US1998/011821 patent/WO1998057933A1/en not_active Application Discontinuation
- 1998-06-15 ZA ZA985209A patent/ZA985209B/en unknown
- 1998-06-16 AR ARP980102851A patent/AR016071A1/en unknown
-
1999
- 1999-12-10 BG BG103986A patent/BG103986A/en unknown
- 1999-12-16 NO NO996244A patent/NO996244L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AR016071A1 (en) | 2001-06-20 |
| WO1998057933A1 (en) | 1998-12-23 |
| AU7826398A (en) | 1999-01-04 |
| BG103986A (en) | 2000-08-31 |
| NO996244L (en) | 2000-01-12 |
| HUP0002681A2 (en) | 2001-08-28 |
| NO996244D0 (en) | 1999-12-16 |
| ZA985209B (en) | 1999-01-06 |
| HUP0002681A3 (en) | 2001-09-28 |
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