IL125453A0 - 4-(Benzo-1,3-dioxylyl)-pyrrolidine-3-carboxylic acid derivatives as endothelin antagonists - Google Patents

4-(Benzo-1,3-dioxylyl)-pyrrolidine-3-carboxylic acid derivatives as endothelin antagonists

Info

Publication number
IL125453A0
IL125453A0 IL12545397A IL12545397A IL125453A0 IL 125453 A0 IL125453 A0 IL 125453A0 IL 12545397 A IL12545397 A IL 12545397A IL 12545397 A IL12545397 A IL 12545397A IL 125453 A0 IL125453 A0 IL 125453A0
Authority
IL
Israel
Prior art keywords
dioxylyl
pyrrolidine
benzo
carboxylic acid
acid derivatives
Prior art date
Application number
IL12545397A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of IL125453A0 publication Critical patent/IL125453A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL12545397A 1996-02-13 1997-02-10 4-(Benzo-1,3-dioxylyl)-pyrrolidine-3-carboxylic acid derivatives as endothelin antagonists IL125453A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60072496A 1996-02-13 1996-02-13
US79450597A 1997-02-04 1997-02-04
PCT/US1997/002128 WO1997030046A1 (fr) 1996-02-13 1997-02-10 Derives d'acide 4-(benzo-1,3-dioxolyl)-pyrrolidine-3-carboxylique utilises comme antagonistes de l'endotheline

Publications (1)

Publication Number Publication Date
IL125453A0 true IL125453A0 (en) 1999-03-12

Family

ID=27083691

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12545397A IL125453A0 (en) 1996-02-13 1997-02-10 4-(Benzo-1,3-dioxylyl)-pyrrolidine-3-carboxylic acid derivatives as endothelin antagonists

Country Status (18)

Country Link
EP (1) EP0888340B1 (fr)
JP (1) JP2000504727A (fr)
CN (1) CN1079397C (fr)
AR (1) AR005801A1 (fr)
AT (1) ATE220673T1 (fr)
AU (1) AU714597B2 (fr)
BR (1) BR9707394A (fr)
CA (1) CA2245684A1 (fr)
CZ (1) CZ253698A3 (fr)
DE (1) DE69714024T2 (fr)
DK (1) DK0888340T3 (fr)
ES (1) ES2182029T3 (fr)
HU (1) HUP9902316A3 (fr)
IL (1) IL125453A0 (fr)
NZ (2) NZ331124A (fr)
PT (1) PT888340E (fr)
WO (1) WO1997030046A1 (fr)
ZA (1) ZA971184B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7208517B1 (en) 1994-08-19 2007-04-24 Abbott Labortories Endothelin antagonists
US6162927A (en) 1994-08-19 2000-12-19 Abbott Laboratories Endothelin antagonists
US6124341A (en) * 1996-02-13 2000-09-26 Abbott Laboratories Endothelin antagonists
WO1998057933A1 (fr) * 1997-06-17 1998-12-23 Abbott Laboratories Derives d'acide carboxylique de pyrrolidine comme antagonistes d'endotheline
CA2297894A1 (fr) * 1997-08-04 1999-02-11 Abbott Laboratories Antagonistes d'endotheline
AU7847901A (en) 2000-07-19 2002-02-05 Hoffmann La Roche Pyrrolidine derivatives as metalloprotease inhibitors
WO2002017912A1 (fr) * 2000-08-31 2002-03-07 Abbott Laboratories Antagonistes de l'endotheline
RU2259825C9 (ru) 2001-06-18 2006-04-10 БиоДием Лимитед Вещества, проявляющие антимикробную, антигрибковую, антипротозойную активности

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2667294B2 (ja) * 1991-11-05 1997-10-27 スミスクライン・ビーチャム・コーポレイション エンドセリン受容体拮抗剤
DE69327720T2 (de) * 1992-07-17 2000-07-27 Smithkline Beecham Corp., Philadelphia Endothelin rezeptor antagonisten
ES2179881T3 (es) * 1994-08-19 2003-02-01 Abbott Lab Antagonistas de endotelina.

Also Published As

Publication number Publication date
BR9707394A (pt) 1999-04-06
AU2267897A (en) 1997-09-02
EP0888340A1 (fr) 1999-01-07
CZ253698A3 (cs) 1999-03-17
CN1079397C (zh) 2002-02-20
NZ331124A (en) 2000-05-26
ES2182029T3 (es) 2003-03-01
JP2000504727A (ja) 2000-04-18
WO1997030046A1 (fr) 1997-08-21
AR005801A1 (es) 1999-07-14
ZA971184B (en) 1997-08-27
DE69714024D1 (de) 2002-08-22
ATE220673T1 (de) 2002-08-15
NZ503383A (en) 2002-02-01
HUP9902316A3 (en) 2001-12-28
CN1215401A (zh) 1999-04-28
DK0888340T3 (da) 2002-11-04
PT888340E (pt) 2002-12-31
DE69714024T2 (de) 2003-03-20
HUP9902316A2 (hu) 1999-11-29
AU714597B2 (en) 2000-01-06
CA2245684A1 (fr) 1997-08-21
EP0888340B1 (fr) 2002-07-17

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