ZA967474B - Production of tryptophan by the bacterium escherichia coli. - Google Patents

Production of tryptophan by the bacterium escherichia coli.

Info

Publication number
ZA967474B
ZA967474B ZA9607474A ZA967474A ZA967474B ZA 967474 B ZA967474 B ZA 967474B ZA 9607474 A ZA9607474 A ZA 9607474A ZA 967474 A ZA967474 A ZA 967474A ZA 967474 B ZA967474 B ZA 967474B
Authority
ZA
South Africa
Prior art keywords
tryptophan
mtr
strains
fermentation
absence
Prior art date
Application number
ZA9607474A
Other languages
English (en)
Inventor
Helen Camakaris
Peter Cowan
James Pittard
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of ZA967474B publication Critical patent/ZA967474B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA9607474A 1995-09-05 1996-09-04 Production of tryptophan by the bacterium escherichia coli. ZA967474B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9518076A GB2304718B (en) 1995-09-05 1995-09-05 The production of tryptophan by the bacterium escherichia coli

Publications (1)

Publication Number Publication Date
ZA967474B true ZA967474B (en) 1998-02-27

Family

ID=10780212

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9607474A ZA967474B (en) 1995-09-05 1996-09-04 Production of tryptophan by the bacterium escherichia coli.

Country Status (13)

Country Link
US (1) US5756345A (xx)
EP (1) EP0789073B1 (xx)
JP (1) JPH09121846A (xx)
KR (1) KR100452572B1 (xx)
AT (1) ATE204324T1 (xx)
AU (1) AU712821B2 (xx)
BR (1) BR9603654A (xx)
CA (1) CA2184760A1 (xx)
DE (1) DE69614498T2 (xx)
GB (1) GB2304718B (xx)
MX (1) MX9603641A (xx)
SK (1) SK282954B6 (xx)
ZA (1) ZA967474B (xx)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6118047A (en) 1993-08-25 2000-09-12 Dekalb Genetic Corporation Anthranilate synthase gene and method of use thereof for conferring tryptophan overproduction
IL140918A0 (en) 1998-07-27 2002-02-10 Genentech Inc Improved transformation efficiency in phage display through modification of a coat protein
US20030096379A1 (en) * 2001-03-28 2003-05-22 Kilgore James L. Method for producing tryptamine derivatives
MXPA04004874A (es) 2001-11-23 2004-09-03 Ajinomoto Kk Procedimiento para producir l-aminoacido utilizando escherichia.
PL208998B1 (pl) * 2002-04-23 2011-07-29 Cargill Sposób wytwarzania monatyny
ATE486936T1 (de) * 2003-03-05 2010-11-15 Chemo Sero Therapeut Res Inst Verfahren zur herstellung eines heterologen proteins in e. coli
JP2007501004A (ja) 2003-08-01 2007-01-25 カーギル，インコーポレイティド モナチン卓上甘味料組成物およびその製造方法
KR101158592B1 (ko) * 2003-10-21 2012-06-22 카아길, 인코포레이팃드 모나틴 및 모나틴 전구체의 생산
KR101142885B1 (ko) * 2003-12-15 2012-05-10 씨제이제일제당 (주) 트립토판 생합성 관련 변이유전자를 함유한 대장균 변이주및 이를 이용한 트립토판 제조방법
DE102005018835A1 (de) 2005-04-22 2006-11-02 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung verbesserter Stämme der Familie Enterobacteriaceae
DE102005019040A1 (de) 2005-04-23 2006-10-26 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung verbesserter Stämme der Familie Enterobacteriaceae
JP2009118740A (ja) 2006-03-03 2009-06-04 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
EP2004803A2 (en) 2006-03-23 2008-12-24 Ajinomoto Co., Inc. A method for producing an l-amino acid using bacterium of theenterobacteriaceae family with attenuated expression of a gene coding for small rna
JP2009165355A (ja) 2006-04-28 2009-07-30 Ajinomoto Co Inc Ｌ−アミノ酸を生産する微生物及びｌ−アミノ酸の製造法
JP2010017082A (ja) 2006-10-10 2010-01-28 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
RU2006143864A (ru) 2006-12-12 2008-06-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНОВ cynT, cynS, cynX, ИЛИ cynR, ИЛИ ИХ КОМБИНАЦИИ
KR100850853B1 (ko) * 2006-12-13 2008-08-06 씨제이제일제당 (주) ｎｒｆＥ 유전자가 불활성화된 Ｌ-트립토판 생산 미생물 및이를 이용한 Ｌ-트립토판 제조방법
KR100792095B1 (ko) * 2006-12-29 2008-01-04 씨제이 주식회사 Ｌ-페닐알라닌 생산능을 갖는 대장균 변이주로부터유전자조작된 ｌ-트립토판 생산능을 갖는 재조합 대장균균주 및 이를 이용한 트립토판 제조방법
WO2008090770A1 (ja) 2007-01-22 2008-07-31 Ajinomoto Co., Inc. Ｌ－アミノ酸を生産する微生物及びｌ－アミノ酸の製造法
JP2010110216A (ja) 2007-02-20 2010-05-20 Ajinomoto Co Inc Ｌ−アミノ酸または核酸の製造方法
JP2010110217A (ja) 2007-02-22 2010-05-20 Ajinomoto Co Inc Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法
DE102007051024A1 (de) 2007-03-05 2008-09-11 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
EP1975241A1 (de) 2007-03-29 2008-10-01 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
CN101939412B (zh) 2007-09-04 2016-01-20 味之素株式会社 生产氨基酸的微生物以及氨基酸的生产方法
DE102007044134A1 (de) 2007-09-15 2009-03-19 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
RU2396336C2 (ru) 2007-09-27 2010-08-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia
DE102007052270A1 (de) 2007-11-02 2009-05-07 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
EP2060636A1 (de) 2007-11-14 2009-05-20 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
JP2011067095A (ja) 2008-01-10 2011-04-07 Ajinomoto Co Inc 発酵法による目的物質の製造法
WO2009093703A1 (ja) 2008-01-23 2009-07-30 Ajinomoto Co., Inc. Ｌ-アミノ酸の製造法
RU2008105793A (ru) 2008-02-19 2009-08-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Способ конструирования оперонов, содержащих трансляционно сопряженные гены, бактерия, содержащая такой оперон, способ продукции полезного метаболита и способ мониторинга экспрессии гена
EP2098597A1 (de) 2008-03-04 2009-09-09 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
DE102008002309A1 (de) 2008-06-09 2009-12-10 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
DE102008040352A1 (de) 2008-07-11 2010-01-14 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Tryptophan unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
DE102008044768A1 (de) 2008-08-28 2010-03-04 Evonik Degussa Gmbh Verfahren zur Herstellung von organisch-chemischen Verbindungen unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
EP2336347B1 (en) 2008-09-08 2017-03-15 Ajinomoto Co., Inc. An l-amino acid-producing microorganism and a method for producing an l-amino acid
EP2382320B1 (en) 2009-01-23 2018-04-18 Ajinomoto Co., Inc. Process for producing l-amino acids employing bacteria of the enterobacteriacea family in a culture medium with controlled glycerol concentration
EP2267145A1 (de) 2009-06-24 2010-12-29 Evonik Degussa GmbH Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
DE102009030342A1 (de) 2009-06-25 2010-12-30 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von organisch chemischen Verbindungen
JPWO2011013707A1 (ja) 2009-07-29 2013-01-10 味の素株式会社 Ｌ−アミノ酸の製造法
JP2012223092A (ja) 2009-08-28 2012-11-15 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2013013329A (ja) 2009-11-06 2013-01-24 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
RU2460793C2 (ru) 2010-01-15 2012-09-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) Способ получения l-аминокислот с использованием бактерий семейства enterobacteriaceae
NZ601950A (en) 2010-01-26 2015-02-27 Meiji Seika Pharma Co Ltd Method for producing pyripyropene
JP2013074795A (ja) 2010-02-08 2013-04-25 Ajinomoto Co Inc 変異型ｒｐｓＡ遺伝子及びＬ−アミノ酸の製造法
RU2471868C2 (ru) 2010-02-18 2013-01-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) Мутантная аденилатциклаза, днк, кодирующая ее, бактерия семейства enterobacteriaceae, содержащая указанную днк, и способ получения l-аминокислот
RU2501858C2 (ru) 2010-07-21 2013-12-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae
RU2482188C2 (ru) 2010-07-21 2013-05-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ L-АРГИНИНА С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ РОДА Escherichia, В КОТОРОЙ ИНАКТИВИРОВАН ОПЕРОН astCADBE
JP2014036576A (ja) 2010-12-10 2014-02-27 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
DE102011006716A1 (de) 2011-04-04 2012-10-04 Evonik Degussa Gmbh Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung
DE102011118019A1 (de) 2011-06-28 2013-01-03 Evonik Degussa Gmbh Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens
RU2011134436A (ru) 2011-08-18 2013-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Способ получения l-аминокислоты с использованием бактерии семейства enterobacteriaceae, обладающей повышенной экспрессией генов каскада образования флагелл и клеточной подвижности
RU2593957C2 (ru) * 2012-01-10 2016-08-10 СиДжей ЧЕИЛДЗЕДАНГ КОРПОРЕЙШН МИКРООРГАНИЗМ ИЗ РОДА Escherichia, ОБЛАДАЮЩИЙ УСИЛЕННОЙ СПОСОБНОСТЬЮ К ПРОДУКЦИИ L-ТРИПТОФАНА, И СПОСОБ ПОЛУЧЕНИЯ L-ТРИПТОФАНА С ЕГО ИСПОЛЬЗОВАНИЕМ
EP2628792A1 (de) 2012-02-17 2013-08-21 Evonik Industries AG Zelle mit verringerter ppGppase-Aktivität
CN104302765B (zh) 2012-04-27 2018-09-11 赢创工业化学有限公司 反馈抗性α-异丙基苹果酸合酶
DE102012024435A1 (de) 2012-12-14 2014-07-10 Forschungszentrum Jülich GmbH Verfahren zur Identifizierung einer Zelle mit gegenüber ihrem Wildtyp erhöhten intrazellulären Konzentration eines bestimmten Metaboliten, wobei die Veränderung der Zelle durch Rekombi-neering erreicht wird, sowie ein Verfahren zur Herstellung einer gegenüber ihrem Wildtyp genetisch veränderten Produktionszelle mit optimierter Produktion eines bestimmten Metaboliten, ein Verfahren zur Herstellung dieses Metaboliten, sowie dafür geeignete Nukleinsäuren
EP2762571A1 (de) 2013-01-30 2014-08-06 Evonik Industries AG Mikroorganismus und Verfahren zur fermentativen Herstellung von Aminosäuren
RU2013118637A (ru) 2013-04-23 2014-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, В КОТОРОЙ РАЗРЕГУЛИРОВАН ГЕН yjjK
DK2811028T3 (en) 2013-06-03 2017-05-01 Evonik Degussa Gmbh Process for Preparation of L-Valine Using Recombinant Coryn Bacteria Containing the Propionate Inducible IlvBN Operon
RU2013140115A (ru) 2013-08-30 2015-03-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ НАРУШЕНА ЭКСПРЕССИЯ КЛАСТЕРА ГЕНОВ znuACB
JP2016192903A (ja) 2013-09-17 2016-11-17 味の素株式会社 海藻由来バイオマスからのｌ−アミノ酸の製造方法
ES2761596T3 (es) 2013-10-02 2020-05-20 Ajinomoto Kk Aparato de control de amoniaco y método de control de amoniaco
RU2013144250A (ru) 2013-10-02 2015-04-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА, КОДИРУЮЩЕГО ФОСФАТНЫЙ ТРАНСПОРТЕР
WO2015060314A1 (ja) 2013-10-21 2015-04-30 味の素株式会社 Ｌ－アミノ酸の製造法
RU2014105547A (ru) 2014-02-14 2015-08-20 Адзиномото Ко., Инк. СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, ИМЕЮЩЕЙ СВЕРХЭКСПРЕССИРУЕМЫЙ ГЕН yajL
EP3143153A4 (en) 2014-05-16 2018-01-03 The University Of Georgia Research Foundation, Inc. Microbial approach for the production of 5-hydroxytryptophan
US9663768B2 (en) 2014-09-02 2017-05-30 University Of Georgia Research Foundation, Inc. Precursor-directed biosynthesis of 5-hydroxytryptophan
RU2015120052A (ru) 2015-05-28 2016-12-20 Аджиномото Ко., Инк. Способ получения L-аминокислоты с использованием бактерии семейства Enterobacteriaceae, в которой ослаблена экспрессия гена gshA
US9988624B2 (en) 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
US11208649B2 (en) 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
WO2017100376A2 (en) 2015-12-07 2017-06-15 Zymergen, Inc. Promoters from corynebacterium glutamicum
WO2017146195A1 (en) 2016-02-25 2017-08-31 Ajinomoto Co., Inc. A method for producing l-amino acids using a bacterium of the family enterobacteriaceae overexpressing a gene encoding an iron exporter
KR102345899B1 (ko) 2016-06-30 2021-12-31 지머젠 인코포레이티드 박테리아 헤모글로빈 라이브러리를 생성하는 방법 및 이의 용도
WO2018005793A1 (en) 2016-06-30 2018-01-04 Zymergen Inc. Methods for generating a glucose permease library and uses thereof
CN111601897A (zh) 2016-12-30 2020-08-28 奎多公司 用于确定细菌对抗生素或益菌剂的易感性的噬菌体介导的免疫分析和方法
JP7066977B2 (ja) 2017-04-03 2022-05-16 味の素株式会社 Ｌ－アミノ酸の製造法
EP3385275B1 (de) 2017-04-07 2019-10-23 Evonik Degussa GmbH Verfahren zur herstellung von aromatischen l-aminosäuren unter verwendung von verbesserten stämmen der familie enterobacteriaceae
JP2020524492A (ja) 2017-06-07 2020-08-20 ザイマージェン インコーポレイテッド Ｃｏｒｙｎｅｂａｃｔｅｒｉｕｍ ｇｌｕｔａｍｉｃｕｍ由来のプロモーターおよび補助遺伝子発現の制御におけるその使用
CA3076516A1 (en) 2017-10-02 2019-04-11 Quidel Corporation Phage-based detection method for antimicrobial susceptibility testing and identification of bacterial species
US11053526B2 (en) 2018-08-09 2021-07-06 Evonik Operations Gmbh Process for preparing L amino acids using improved strains of the enterobacteriaceae family
EP3608409A1 (en) 2018-08-09 2020-02-12 Evonik Operations GmbH Process for preparing l amino acids using improved strains of the enterobacteriaceae family
EP3861109A1 (en) 2018-10-05 2021-08-11 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
EP3677594A1 (en) 2019-01-07 2020-07-08 Evonik Operations GmbH Method for producing l-tryptophan using improved strains of the enterobacteriaceae family
WO2020171227A1 (en) 2019-02-22 2020-08-27 Ajinomoto Co., Inc. METHOD FOR PRODUCING L-AMINO ACIDS USING A BACTERIUM BELONGING TO THE FAMILY Enterobacteriaceae HAVING OVEREXPRESSED ydiJ GENE
BR112021017870A2 (pt) 2019-04-05 2021-12-07 Ajinomoto Kk Método para produzir um l-aminoácido
JP2022550084A (ja) 2019-09-25 2022-11-30 味の素株式会社 細菌の発酵によるｌ－アミノ酸の製造方法
EP4182450A1 (en) 2020-07-15 2023-05-24 Evonik Operations GmbH Polynucleotide encoding an amino acid sequence, encoding an oxidoreductase
EP4384537A1 (en) 2021-08-09 2024-06-19 Evonik Operations GmbH Method for producing a recombinant bacterial collagen-like protein (clp)
WO2023016895A1 (en) 2021-08-09 2023-02-16 Evonik Operations Gmbh Polynucleotide encoding a bacterial collagen-like protein
EP4384538A1 (en) 2021-08-09 2024-06-19 Evonik Operations GmbH Method for producing a recombinant bacterial collagen-like protein (clp)
CN117999103A (zh) 2021-09-20 2024-05-07 赢创运营有限公司 非粘附性胶原蛋白样水凝胶
CN114480173B (zh) * 2021-12-27 2024-02-09 江苏澳创生物科技有限公司 一株大肠埃希氏菌及其在发酵生产l-色氨酸中的应用
WO2023161038A1 (en) 2022-02-25 2023-08-31 Evonik Operations Gmbh Sponges based on collagen-like proteins
WO2023165952A1 (en) 2022-03-01 2023-09-07 Evonik Operations Gmbh Biotechnological production of collagen proteins and bacterial collagen-like proteins by recombinant microorganisms

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4371614A (en) * 1980-08-22 1983-02-01 Ajinomoto Co., Inc. E.Coli bacteria carrying recombinant plasmids and their use in the fermentative production of L-tryptophan
US4743546A (en) * 1985-02-13 1988-05-10 Biotechnica International, Inc. Controlled gene excision
JPS61247393A (ja) * 1985-04-26 1986-11-04 Res Assoc Util Of Light Oil Ｌ−トリプトフアンの製造方法
JPS62208284A (ja) * 1986-03-10 1987-09-12 Sanraku Inc 新規なプラスミド
AU1753092A (en) * 1991-04-05 1992-11-02 Upjohn Company, The Trpr mutations effective in the expression of small proteins and peptides
TW258753B (en) * 1992-06-30 1995-10-01 Dev Center Biotechnology Direct fermentation of L-tryptophan by a recombinant microbe
DE4232468A1 (de) * 1992-09-28 1994-03-31 Consortium Elektrochem Ind Mikroorganismen für die Produktion von Tryptophan und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
DE69614498D1 (de) 2001-09-20
EP0789073B1 (en) 2001-08-16
CA2184760A1 (en) 1997-03-06
EP0789073A2 (en) 1997-08-13
MX9603641A (es) 1997-03-29
JPH09121846A (ja) 1997-05-13
DE69614498T2 (de) 2002-05-23
KR100452572B1 (ko) 2005-02-07
SK111096A3 (en) 1997-05-07
BR9603654A (pt) 1998-05-19
US5756345A (en) 1998-05-26
GB2304718B (en) 2000-01-19
AU6445296A (en) 1997-03-13
GB2304718A (en) 1997-03-26
EP0789073A3 (en) 1998-09-23
ATE204324T1 (de) 2001-09-15
GB9518076D0 (en) 1995-11-08
KR970015739A (ko) 1997-04-28
SK282954B6 (sk) 2003-01-09
AU712821B2 (en) 1999-11-18

Similar Documents

Publication Publication Date Title
GB2304718B (en) The production of tryptophan by the bacterium escherichia coli
US4757009A (en) Recombinant DNA having a phosphoenol pyruvate carboxylase gene inserted therein, bacteria carrying said recombinant DNA and a process for producing amino acids using said bacteria
RU2111247C1 (ru) Способ получения штамма микроорганизма, способ продуцирования триптофана
EP0082485A2 (en) Novel vector plasmids
HU196843B (en) Process for producing l-lysine
JPH06102028B2 (ja) アミノ酸の製造法
AU784733B2 (en) Process for producing a target fermentation product
US7582460B2 (en) 3-phosphoglycerate dehydrogenase variants whose inhibition by L-serine is reduced, and genes encoding them
Pauli et al. Fatty acid degradation in Escherichia coli: requirement of cyclic adenosine monophosphate and cyclic adenosine monophosphate receptor protein for enzyme synthesis
JPH0728749B2 (ja) Ｌ−アルギニンの製造法
US4968609A (en) Coryneform bacteria carrying recombinant DNA and a process for producing aromatic amino acids using said bacteria
GB2130216A (en) Enzymatic synthesis of L-serine
Bloom et al. Positive control in the D-serine deaminase system of Escherichia coli K-12
US5017481A (en) Coryneform bacteria carrying recombinant DNA and process for producing an aromatic amino acid by using the same
CA1228038A (en) Process for producing tyrosine
JPH0755155B2 (ja) アミノ酸の製造法
US6277609B1 (en) Method to produce biotin
EP0180192A1 (en) Novel plasmids
EP0293207A2 (en) Eschericia coli carrying recombinant plasmid for the production of tryptophan
WO2023085875A1 (ko) 클래스 I 타입의 BirA를 포함하는 미생물 및 이를 이용한 바이오틴 생산방법
Guardiola et al. Dual autogenous regulatory role of threonine deaminase in Escherichia coli K-12
Chung et al. Transformation and Mutation of Bacillus licheniformis 9945a Producing ${\gamma}-Poly (glutamic\; acid) $
JPH055479B2 (xx)
Brighton et al. BACTERIUM ESCHERICHIA COLI
JPH0468909B2 (xx)