ZA942255B - HIV protease inhibitors useful for the treatment of AIDS. - Google Patents

HIV protease inhibitors useful for the treatment of AIDS.

Info

Publication number
ZA942255B
ZA942255B ZA942255A ZA942255A ZA942255B ZA 942255 B ZA942255 B ZA 942255B ZA 942255 A ZA942255 A ZA 942255A ZA 942255 A ZA942255 A ZA 942255A ZA 942255 B ZA942255 B ZA 942255B
Authority
ZA
South Africa
Prior art keywords
treatment
aids
protease inhibitors
compounds
hiv protease
Prior art date
Application number
ZA942255A
Other languages
English (en)
Inventor
Joseph P Vacca
James P Guare
Bruce D Dorsey
M Katharine Holloway
Randall W Hungate
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA942255B publication Critical patent/ZA942255B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA942255A 1993-03-31 1994-03-30 HIV protease inhibitors useful for the treatment of AIDS. ZA942255B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4072993A 1993-03-31 1993-03-31

Publications (1)

Publication Number Publication Date
ZA942255B true ZA942255B (en) 1994-11-01

Family

ID=21912617

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA942255A ZA942255B (en) 1993-03-31 1994-03-30 HIV protease inhibitors useful for the treatment of AIDS.

Country Status (35)

Country Link
EP (1) EP0617968B1 (ko)
JP (1) JPH08508496A (ko)
KR (1) KR100311551B1 (ko)
CN (1) CN1090186C (ko)
AT (1) ATE230610T1 (ko)
AU (1) AU685772B2 (ko)
BG (1) BG62083B1 (ko)
BR (1) BR9406503A (ko)
CA (1) CA2120192A1 (ko)
CY (1) CY2326B1 (ko)
CZ (1) CZ286412B6 (ko)
DE (1) DE69431972T2 (ko)
DK (1) DK0617968T3 (ko)
DZ (1) DZ1766A1 (ko)
ES (1) ES2188604T3 (ko)
FI (1) FI954580A0 (ko)
HK (1) HK1009248A1 (ko)
HR (1) HRP940209B1 (ko)
HU (1) HUT74006A (ko)
IL (1) IL109166A (ko)
LV (1) LV13141B (ko)
NO (1) NO953876L (ko)
NZ (1) NZ265164A (ko)
PL (1) PL310895A1 (ko)
PT (1) PT617968E (ko)
RO (1) RO118000B1 (ko)
RU (1) RU2139052C1 (ko)
SA (1) SA94140745B1 (ko)
SG (1) SG64366A1 (ko)
SI (1) SI9420017B (ko)
SK (1) SK279471B6 (ko)
TW (1) TW307684B (ko)
WO (1) WO1994022480A1 (ko)
YU (1) YU49275B (ko)
ZA (1) ZA942255B (ko)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ278201A (en) * 1993-12-15 1998-01-26 Merck & Co Inc Bicyclic heterocyclically substituted piperazine derivatives as hiv protease inhibitors
UA49803C2 (uk) * 1994-06-03 2002-10-15 Дж.Д. Сьорль Енд Ко Спосіб лікування ретровірусних інфекцій
US5476874A (en) * 1994-06-22 1995-12-19 Merck & Co., Inc. New HIV protease inhibitors
WO1996012492A1 (en) * 1994-10-25 1996-05-02 Merck & Co., Inc. Microbial synthesis of hiv protease inhibitors
US6689761B1 (en) 1995-02-01 2004-02-10 Merck & Co., Inc. Combination therapy for HIV infection
US6262093B1 (en) 1995-04-12 2001-07-17 The Proctor & Gamble Company Methods of treating cancer with benzimidazoles
US6479526B1 (en) 1995-04-12 2002-11-12 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of viruses and cancers
US6265427B1 (en) 1995-06-07 2001-07-24 The Proctor & Gamble Company Pharmaceutical composition for the method of treating leukemia
US5900429A (en) 1997-01-28 1999-05-04 The Procter & Gamble Company Method for inhibiting the growth of cancers
US6506783B1 (en) 1997-05-16 2003-01-14 The Procter & Gamble Company Cancer treatments and pharmaceutical compositions therefor
PE11499A1 (es) * 1997-05-16 1999-03-01 Procter & Gamble Tratamiento del hiv y cancer
HU9701081D0 (en) * 1997-06-23 1997-08-28 Gene Research Lab Inc N Pharmaceutical composition of antitumoral activity
US6245789B1 (en) 1998-05-19 2001-06-12 The Procter & Gamble Company HIV and viral treatment
WO2000002862A1 (en) 1998-07-08 2000-01-20 G.D. Searle & Co. Retroviral protease inhibitors
AU6508899A (en) * 1998-10-13 2000-05-01 Du Pont Pharmaceuticals Company Selective eradication of virally-infected cells by combined use of a cytotoxic agent and an antiviral agent
US6423734B1 (en) 1999-08-13 2002-07-23 The Procter & Gamble Company Method of preventing cancer
US6608096B1 (en) 2000-09-26 2003-08-19 University Of Arizona Foundation Compounds and methods for use thereof in the treatment of cancer or viral infections
US6462062B1 (en) 2000-09-26 2002-10-08 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6380232B1 (en) 2000-09-26 2002-04-30 The Procter & Gamble Company Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof
US6407105B1 (en) 2000-09-26 2002-06-18 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
AU2005275181A1 (en) 2004-07-14 2006-02-23 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7772271B2 (en) 2004-07-14 2010-08-10 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7868037B2 (en) 2004-07-14 2011-01-11 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7645881B2 (en) 2004-07-22 2010-01-12 Ptc Therapeutics, Inc. Methods for treating hepatitis C
RU2520967C1 (ru) * 2013-02-08 2014-06-27 Федеральное государственное бюджетное учреждение науки Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) СИММЕТРИЧНЫЕ ДИИМИНЫ НА ОСНОВЕ КАМФОРЫ - ИНГИБИТОРЫ РЕПРОДУКЦИИ ВИРУСА ГРИППА (ШТАММ A/California/07/09 (H1N1)pdm09)
CN109528747A (zh) * 2018-12-13 2019-03-29 中国人民解放军总医院 扎西他滨在制备抗菌消炎药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06508146A (ja) * 1991-06-04 1994-09-14 スミスクライン・ビーチャム・コーポレイション 炭素環および複素環式hivプロテアーゼ抑制剤

Also Published As

Publication number Publication date
AU685772B2 (en) 1998-01-29
KR100311551B1 (ko) 2001-12-28
CY2326B1 (en) 2003-11-14
CN1120316A (zh) 1996-04-10
NO953876L (no) 1995-11-30
CN1090186C (zh) 2002-09-04
PT617968E (pt) 2003-03-31
BR9406503A (pt) 1996-01-02
CZ252895A3 (en) 1996-07-17
RU2139052C1 (ru) 1999-10-10
NO953876D0 (no) 1995-09-29
HRP940209A2 (en) 1998-02-28
RO118000B1 (ro) 2002-12-30
ES2188604T3 (es) 2003-07-01
PL310895A1 (en) 1996-01-08
DZ1766A1 (fr) 2002-02-17
HUT74006A (en) 1996-10-28
CZ286412B6 (en) 2000-04-12
AU5921394A (en) 1994-10-06
HRP940209B1 (en) 2004-04-30
IL109166A (en) 1999-08-17
HK1009248A1 (en) 1999-05-28
SK279471B6 (sk) 1998-11-04
CA2120192A1 (en) 1994-10-01
NZ265164A (en) 1997-09-22
BG62083B1 (bg) 1999-02-26
SI9420017B (sl) 2003-12-31
SG64366A1 (en) 1999-04-27
IL109166A0 (en) 1994-06-24
SA94140745B1 (ar) 2006-07-11
FI954580A (fi) 1995-09-27
SK122595A3 (en) 1997-03-05
YU49275B (sh) 2005-03-15
SI9420017A (en) 1996-10-31
WO1994022480A1 (en) 1994-10-13
YU15994A (sh) 1999-06-15
DK0617968T3 (da) 2003-02-24
DE69431972D1 (de) 2003-02-13
LV13141B (en) 2004-08-20
JPH08508496A (ja) 1996-09-10
TW307684B (ko) 1997-06-11
KR960701661A (ko) 1996-03-28
BG100016A (en) 1996-04-30
EP0617968A1 (en) 1994-10-05
FI954580A0 (fi) 1995-09-27
HU9502860D0 (en) 1995-11-28
DE69431972T2 (de) 2003-08-28
EP0617968B1 (en) 2003-01-08
ATE230610T1 (de) 2003-01-15

Similar Documents

Publication Publication Date Title
HRP940209B1 (en) Hiv protease inhibitors useful for the treatment of aids
AU2725392A (en) Hiv protease inhibitors
IN172553B (ko)
EP0766674A4 (en) NOVEL HIV PROTEASE INHIBITORS
PL314984A1 (en) Hiv protease inhibitors
IL114808A0 (en) Combination therapy for hiv