DE69431972T2 - HIV Protease Hemmer in pharmazeutischen Zusammensetzungen zur Behandlung von AIDS - Google Patents

HIV Protease Hemmer in pharmazeutischen Zusammensetzungen zur Behandlung von AIDS

Info

Publication number
DE69431972T2
DE69431972T2 DE69431972T DE69431972T DE69431972T2 DE 69431972 T2 DE69431972 T2 DE 69431972T2 DE 69431972 T DE69431972 T DE 69431972T DE 69431972 T DE69431972 T DE 69431972T DE 69431972 T2 DE69431972 T2 DE 69431972T2
Authority
DE
Germany
Prior art keywords
treatment
aids
protease inhibitors
hiv protease
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69431972T
Other languages
English (en)
Other versions
DE69431972D1 (de
Inventor
Joseph P Vacca
M Katharine Holloway
James P Guare
Randall W Hungate
Bruce D Dorsey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE69431972D1 publication Critical patent/DE69431972D1/de
Application granted granted Critical
Publication of DE69431972T2 publication Critical patent/DE69431972T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69431972T 1993-03-31 1994-03-29 HIV Protease Hemmer in pharmazeutischen Zusammensetzungen zur Behandlung von AIDS Expired - Fee Related DE69431972T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4072993A 1993-03-31 1993-03-31

Publications (2)

Publication Number Publication Date
DE69431972D1 DE69431972D1 (de) 2003-02-13
DE69431972T2 true DE69431972T2 (de) 2003-08-28

Family

ID=21912617

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69431972T Expired - Fee Related DE69431972T2 (de) 1993-03-31 1994-03-29 HIV Protease Hemmer in pharmazeutischen Zusammensetzungen zur Behandlung von AIDS

Country Status (35)

Country Link
EP (1) EP0617968B1 (de)
JP (1) JPH08508496A (de)
KR (1) KR100311551B1 (de)
CN (1) CN1090186C (de)
AT (1) ATE230610T1 (de)
AU (1) AU685772B2 (de)
BG (1) BG62083B1 (de)
BR (1) BR9406503A (de)
CA (1) CA2120192A1 (de)
CY (1) CY2326B1 (de)
CZ (1) CZ286412B6 (de)
DE (1) DE69431972T2 (de)
DK (1) DK0617968T3 (de)
DZ (1) DZ1766A1 (de)
ES (1) ES2188604T3 (de)
FI (1) FI954580A0 (de)
HK (1) HK1009248A1 (de)
HR (1) HRP940209B1 (de)
HU (1) HUT74006A (de)
IL (1) IL109166A (de)
LV (1) LV13141B (de)
NO (1) NO953876L (de)
NZ (1) NZ265164A (de)
PL (1) PL310895A1 (de)
PT (1) PT617968E (de)
RO (1) RO118000B1 (de)
RU (1) RU2139052C1 (de)
SA (1) SA94140745B1 (de)
SG (1) SG64366A1 (de)
SI (1) SI9420017B (de)
SK (1) SK279471B6 (de)
TW (1) TW307684B (de)
WO (1) WO1994022480A1 (de)
YU (1) YU49275B (de)
ZA (1) ZA942255B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ288312B6 (en) * 1993-12-15 2001-05-16 Merck & Co Inc HIV-protease inhibitors and pharmaceutical preparations in which they are comprised
UA49803C2 (uk) * 1994-06-03 2002-10-15 Дж.Д. Сьорль Енд Ко Спосіб лікування ретровірусних інфекцій
US5476874A (en) * 1994-06-22 1995-12-19 Merck & Co., Inc. New HIV protease inhibitors
JPH10507917A (ja) * 1994-10-25 1998-08-04 メルク エンド カンパニー インコーポレーテッド Ｈｉｖプロテアーゼ阻害剤の微生物合成
US6689761B1 (en) 1995-02-01 2004-02-10 Merck & Co., Inc. Combination therapy for HIV infection
US6479526B1 (en) 1995-04-12 2002-11-12 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of viruses and cancers
US6262093B1 (en) 1995-04-12 2001-07-17 The Proctor & Gamble Company Methods of treating cancer with benzimidazoles
US6265427B1 (en) 1995-06-07 2001-07-24 The Proctor & Gamble Company Pharmaceutical composition for the method of treating leukemia
US5900429A (en) 1997-01-28 1999-05-04 The Procter & Gamble Company Method for inhibiting the growth of cancers
PE11499A1 (es) * 1997-05-16 1999-03-01 Procter & Gamble Tratamiento del hiv y cancer
US6506783B1 (en) 1997-05-16 2003-01-14 The Procter & Gamble Company Cancer treatments and pharmaceutical compositions therefor
HU9701081D0 (en) * 1997-06-23 1997-08-28 Gene Research Lab Inc N Pharmaceutical composition of antitumoral activity
US6245789B1 (en) 1998-05-19 2001-06-12 The Procter & Gamble Company HIV and viral treatment
WO2000002862A1 (en) 1998-07-08 2000-01-20 G.D. Searle & Co. Retroviral protease inhibitors
AU6508899A (en) 1998-10-13 2000-05-01 Du Pont Pharmaceuticals Company Selective eradication of virally-infected cells by combined use of a cytotoxic agent and an antiviral agent
US6423734B1 (en) 1999-08-13 2002-07-23 The Procter & Gamble Company Method of preventing cancer
US6462062B1 (en) 2000-09-26 2002-10-08 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6608096B1 (en) 2000-09-26 2003-08-19 University Of Arizona Foundation Compounds and methods for use thereof in the treatment of cancer or viral infections
US6407105B1 (en) 2000-09-26 2002-06-18 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6380232B1 (en) 2000-09-26 2002-04-30 The Procter & Gamble Company Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7772271B2 (en) 2004-07-14 2010-08-10 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US8013006B2 (en) 2004-07-14 2011-09-06 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7868037B2 (en) 2004-07-14 2011-01-11 Ptc Therapeutics, Inc. Methods for treating hepatitis C
MX2007000762A (es) 2004-07-22 2007-04-02 Ptc Therapeutics Inc Tienopiridinas para tratamientode hepatitis c.
RU2520967C1 (ru) * 2013-02-08 2014-06-27 Федеральное государственное бюджетное учреждение науки Новосибирский институт органической химии им. Н.Н. Ворожцова Сибирского отделения Российской академии наук (НИОХ СО РАН) СИММЕТРИЧНЫЕ ДИИМИНЫ НА ОСНОВЕ КАМФОРЫ - ИНГИБИТОРЫ РЕПРОДУКЦИИ ВИРУСА ГРИППА (ШТАММ A/California/07/09 (H1N1)pdm09)
CN109528747A (zh) * 2018-12-13 2019-03-29 中国人民解放军总医院 扎西他滨在制备抗菌消炎药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06508146A (ja) * 1991-06-04 1994-09-14 スミスクライン・ビーチャム・コーポレイション 炭素環および複素環式ｈｉｖプロテアーゼ抑制剤

Also Published As

Publication number Publication date
JPH08508496A (ja) 1996-09-10
RU2139052C1 (ru) 1999-10-10
CZ286412B6 (en) 2000-04-12
HU9502860D0 (en) 1995-11-28
SI9420017B (sl) 2003-12-31
KR960701661A (ko) 1996-03-28
FI954580A (fi) 1995-09-27
LV13141B (en) 2004-08-20
DZ1766A1 (fr) 2002-02-17
IL109166A0 (en) 1994-06-24
CN1090186C (zh) 2002-09-04
HRP940209B1 (en) 2004-04-30
RO118000B1 (ro) 2002-12-30
SI9420017A (en) 1996-10-31
BG100016A (en) 1996-04-30
DE69431972D1 (de) 2003-02-13
CN1120316A (zh) 1996-04-10
TW307684B (de) 1997-06-11
NO953876L (no) 1995-11-30
AU5921394A (en) 1994-10-06
HUT74006A (en) 1996-10-28
ATE230610T1 (de) 2003-01-15
NO953876D0 (no) 1995-09-29
PT617968E (pt) 2003-03-31
YU49275B (sh) 2005-03-15
CZ252895A3 (en) 1996-07-17
EP0617968A1 (de) 1994-10-05
AU685772B2 (en) 1998-01-29
SA94140745B1 (ar) 2006-07-11
HRP940209A2 (en) 1998-02-28
EP0617968B1 (de) 2003-01-08
ZA942255B (en) 1994-11-01
SK122595A3 (en) 1997-03-05
DK0617968T3 (da) 2003-02-24
KR100311551B1 (ko) 2001-12-28
BR9406503A (pt) 1996-01-02
IL109166A (en) 1999-08-17
SK279471B6 (sk) 1998-11-04
SG64366A1 (en) 1999-04-27
ES2188604T3 (es) 2003-07-01
NZ265164A (en) 1997-09-22
PL310895A1 (en) 1996-01-08
BG62083B1 (bg) 1999-02-26
FI954580A0 (fi) 1995-09-27
CA2120192A1 (en) 1994-10-01
WO1994022480A1 (en) 1994-10-13
CY2326B1 (en) 2003-11-14
HK1009248A1 (en) 1999-05-28
YU15994A (sh) 1999-06-15

Similar Documents

Publication Publication Date Title
DE69431972D1 (de) HIV Protease Hemmer in pharmazeutischen Zusammensetzungen zur Behandlung von AIDS
DE69228106T2 (de) HIV-Protease-Inhibitoren
FI905983A (fi) Aminosyraderivat.
DE69531944D1 (de) Neue hiv-protease-inhibitoren
DE69430385D1 (de) Hiv-proteaseinhibitoren

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee