ZA93823B - Process for the preparation of taxane derivatives. - Google Patents

Process for the preparation of taxane derivatives.

Info

Publication number
ZA93823B
ZA93823B ZA93823A ZA93823A ZA93823B ZA 93823 B ZA93823 B ZA 93823B ZA 93823 A ZA93823 A ZA 93823A ZA 93823 A ZA93823 A ZA 93823A ZA 93823 B ZA93823 B ZA 93823B
Authority
ZA
South Africa
Prior art keywords
stands
iii
general formula
hydroxy function
taxane derivatives
Prior art date
Application number
ZA93823A
Other languages
English (en)
Inventor
Elie Fouque
Jean-Manuel Mas
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of ZA93823B publication Critical patent/ZA93823B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA93823A 1992-02-07 1993-02-05 Process for the preparation of taxane derivatives. ZA93823B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9201379A FR2687150B1 (fr) 1992-02-07 1992-02-07 Procede de preparation de derives du taxane.

Publications (1)

Publication Number Publication Date
ZA93823B true ZA93823B (en) 1993-09-16

Family

ID=9426424

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA93823A ZA93823B (en) 1992-02-07 1993-02-05 Process for the preparation of taxane derivatives.

Country Status (24)

Country Link
US (1) US6596880B1 (cs)
EP (1) EP0625147B1 (cs)
JP (1) JP3295879B2 (cs)
KR (1) KR100254167B1 (cs)
AT (1) ATE141920T1 (cs)
AU (1) AU686095B2 (cs)
CA (1) CA2126462C (cs)
CZ (1) CZ283377B6 (cs)
DE (1) DE69304309T2 (cs)
DK (1) DK0625147T3 (cs)
ES (1) ES2090970T3 (cs)
FI (1) FI106959B (cs)
FR (1) FR2687150B1 (cs)
GR (1) GR3020894T3 (cs)
HU (1) HU212577B (cs)
MX (1) MX9300622A (cs)
NO (1) NO305863B1 (cs)
NZ (1) NZ249162A (cs)
PL (1) PL175106B1 (cs)
RU (1) RU2103266C1 (cs)
SK (1) SK280012B6 (cs)
TW (1) TW234122B (cs)
WO (1) WO1993016059A1 (cs)
ZA (1) ZA93823B (cs)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
CA2100808A1 (en) * 1992-10-01 1994-04-02 Vittorio Farina Deoxy paclitaxels
US5948919A (en) * 1993-02-05 1999-09-07 Napro Biotherapeutics, Inc. Paclitaxel synthesis from precursor compounds and methods of producing the same
AU695530B2 (en) * 1993-02-05 1998-08-13 Bryn Mawr College Synthesis of taxol, analogs and intermediates with variable a-ring side chains
US5684175A (en) * 1993-02-05 1997-11-04 Napro Biotherapeutics, Inc. C-2' hydroxyl-benzyl protected, N-carbamate protected (2R, 3S)- 3-phenylisoserine and production process therefor
EP0700910A1 (en) * 1994-09-06 1996-03-13 Shionogi & Co., Ltd. Process for isolation of taxol from Taxus sumatrana
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives
US5675025A (en) * 1995-06-07 1997-10-07 Napro Biotherapeutics, Inc. Paclitaxel synthesis from precursor compounds and methods of producing the same
US6107332A (en) 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6051600A (en) * 1995-09-12 2000-04-18 Mayhew; Eric Liposomal hydrolysis-promoting hydrophobic taxane derivatives
FR2740451B1 (fr) * 1995-10-27 1998-01-16 Seripharm Nouveaux intermediaires pour l'hemisynthese de taxanes, leurs procedes de preparation et leur utilisation dans la synthese generale des taxanes
US5688977A (en) * 1996-02-29 1997-11-18 Napro Biotherapeutics, Inc. Method for docetaxel synthesis
US5750737A (en) * 1996-09-25 1998-05-12 Sisti; Nicholas J. Method for paclitaxel synthesis
MXPA01011046A (es) * 1999-05-17 2002-07-22 Squibb Bristol Myers Co Novedosas condiciones de reaccion para la escicion de teres de sililo en la preparacion de paclitaxel (taxol, marca registrada) y analogos de paclitaxel.
BR0104351A (pt) 2000-02-02 2002-01-02 Univ Florida State Res Found Taxanos substituìdos com carbonato c7 como agentes antitumor
CA2368534A1 (en) 2000-02-02 2001-08-09 Florida State University Research Foundation, Inc. C7 heterosubstituted acetate taxanes as antitumor agents
IT1319168B1 (it) * 2000-03-17 2003-09-26 Indena Spa Derivati di condensazione ad attivita' antitumorale, loro metodo dipreparazione e formulazioni che li contengono.
US6452025B1 (en) 2001-04-25 2002-09-17 Napro Biotherapeutics, Inc. Three-step conversion of protected taxane ester to paclitaxel
WO2005095959A2 (en) * 2004-03-29 2005-10-13 Howard Murad Methods for treating dermatological conditions in a patient
CN100586940C (zh) * 2007-01-26 2010-02-03 上海百灵医药科技有限公司 紫杉醇和多烯紫杉醇的半合成方法
KR101014438B1 (ko) * 2008-09-26 2011-02-14 동아제약주식회사 탁산 유도체의 제조방법
PL388144A1 (pl) 2009-05-29 2010-12-06 Przedsiębiorstwo Produkcyjno-Wdrożeniowe Ifotam Spółka Z Ograniczoną Odpowiedzialnością Solwaty (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylopropionianu 4-acetoksy-2α-benzoiloksy -5β,20-epoksy-1,7β,10β-trihydroksy-9-okso-taks-11-en-13α-ylu, sposób ich otrzymywania i zastosowanie
EP2697211A4 (en) * 2011-04-01 2014-08-13 Shilpa Medicare Ltd PROCESS FOR THE PREPARATION OF DOCETAXEL AND ITS HYDRATE
KR101809858B1 (ko) 2012-04-04 2017-12-15 할로자임, 아이엔씨 항-히알루로난 제제 및 종양-표적 탁산을 이용한 병용 치료
EP2861256B1 (en) 2012-06-15 2019-10-23 The Brigham and Women's Hospital, Inc. Compositions for treating cancer and methods for making the same
MX2016012893A (es) 2014-04-03 2017-05-12 Invictus Oncology Pvt Ltd Sustancias terapéuticas combinadas supramoleculares.
WO2019222435A1 (en) 2018-05-16 2019-11-21 Halozyme, Inc. Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR336841A (fr) 1903-10-29 1904-03-18 James William Mander Perfectionnements apportés aux instruments employés pour le dessin
FR336840A (fr) 1903-10-29 1904-03-18 Emmanuel Saura Machine à piston diviseur
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
FR2629819B1 (fr) 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii

Also Published As

Publication number Publication date
ATE141920T1 (de) 1996-09-15
RU94040356A (ru) 1997-05-27
NO942895D0 (cs) 1994-08-04
DK0625147T3 (da) 1996-11-11
NO942895L (no) 1994-08-04
RU2103266C1 (ru) 1998-01-27
GR3020894T3 (en) 1996-11-30
HU212577B (en) 1996-08-29
JPH07503472A (ja) 1995-04-13
CA2126462C (fr) 2002-07-09
JP3295879B2 (ja) 2002-06-24
MX9300622A (es) 1993-08-01
NO305863B1 (no) 1999-08-09
US6596880B1 (en) 2003-07-22
SK280012B6 (sk) 1999-07-12
HU9402289D0 (en) 1994-10-28
KR950700267A (ko) 1995-01-16
AU3504893A (en) 1993-09-03
FR2687150A1 (fr) 1993-08-13
FI943643A0 (fi) 1994-08-05
FR2687150B1 (fr) 1995-04-28
NZ249162A (en) 1996-10-28
EP0625147B1 (fr) 1996-08-28
ES2090970T3 (es) 1996-10-16
CZ187094A3 (en) 1994-12-15
WO1993016059A1 (fr) 1993-08-19
AU686095B2 (en) 1998-02-05
EP0625147A1 (fr) 1994-11-23
CZ283377B6 (cs) 1998-04-15
FI943643A7 (fi) 1994-08-05
HUT68773A (en) 1995-07-28
FI106959B (fi) 2001-05-15
PL175106B1 (pl) 1998-11-30
DE69304309D1 (de) 1996-10-02
KR100254167B1 (ko) 2000-05-01
DE69304309T2 (de) 1997-01-23
CA2126462A1 (fr) 1993-08-19
SK93094A3 (en) 1995-04-12
TW234122B (cs) 1994-11-11

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