TW234122B - - Google Patents

Info

Publication number
TW234122B
TW234122B TW082100755A TW82100755A TW234122B TW 234122 B TW234122 B TW 234122B TW 082100755 A TW082100755 A TW 082100755A TW 82100755 A TW82100755 A TW 82100755A TW 234122 B TW234122 B TW 234122B
Authority
TW
Taiwan
Prior art keywords
stands
iii
general formula
hydroxy function
function protective
Prior art date
Application number
TW082100755A
Other languages
English (en)
Original Assignee
Rhone Pouleng Rorer S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Pouleng Rorer S A filed Critical Rhone Pouleng Rorer S A
Application granted granted Critical
Publication of TW234122B publication Critical patent/TW234122B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
TW082100755A 1992-02-07 1993-02-04 TW234122B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9201379A FR2687150B1 (fr) 1992-02-07 1992-02-07 Procede de preparation de derives du taxane.

Publications (1)

Publication Number Publication Date
TW234122B true TW234122B (zh) 1994-11-11

Family

ID=9426424

Family Applications (1)

Application Number Title Priority Date Filing Date
TW082100755A TW234122B (zh) 1992-02-07 1993-02-04

Country Status (24)

Country Link
US (1) US6596880B1 (zh)
EP (1) EP0625147B1 (zh)
JP (1) JP3295879B2 (zh)
KR (1) KR100254167B1 (zh)
AT (1) ATE141920T1 (zh)
AU (1) AU686095B2 (zh)
CA (1) CA2126462C (zh)
CZ (1) CZ283377B6 (zh)
DE (1) DE69304309T2 (zh)
DK (1) DK0625147T3 (zh)
ES (1) ES2090970T3 (zh)
FI (1) FI106959B (zh)
FR (1) FR2687150B1 (zh)
GR (1) GR3020894T3 (zh)
HU (1) HU212577B (zh)
MX (1) MX9300622A (zh)
NO (1) NO305863B1 (zh)
NZ (1) NZ249162A (zh)
PL (1) PL175106B1 (zh)
RU (1) RU2103266C1 (zh)
SK (1) SK280012B6 (zh)
TW (1) TW234122B (zh)
WO (1) WO1993016059A1 (zh)
ZA (1) ZA93823B (zh)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
CA2100808A1 (en) * 1992-10-01 1994-04-02 Vittorio Farina Deoxy paclitaxels
AU695530B2 (en) * 1993-02-05 1998-08-13 Bryn Mawr College Synthesis of taxol, analogs and intermediates with variable a-ring side chains
US5684175A (en) * 1993-02-05 1997-11-04 Napro Biotherapeutics, Inc. C-2' hydroxyl-benzyl protected, N-carbamate protected (2R, 3S)- 3-phenylisoserine and production process therefor
US5948919A (en) * 1993-02-05 1999-09-07 Napro Biotherapeutics, Inc. Paclitaxel synthesis from precursor compounds and methods of producing the same
EP0700910A1 (en) * 1994-09-06 1996-03-13 Shionogi & Co., Ltd. Process for isolation of taxol from Taxus sumatrana
US5580899A (en) 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives
US5675025A (en) * 1995-06-07 1997-10-07 Napro Biotherapeutics, Inc. Paclitaxel synthesis from precursor compounds and methods of producing the same
US6051600A (en) * 1995-09-12 2000-04-18 Mayhew; Eric Liposomal hydrolysis-promoting hydrophobic taxane derivatives
US6107332A (en) 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US5688977A (en) * 1996-02-29 1997-11-18 Napro Biotherapeutics, Inc. Method for docetaxel synthesis
US5750737A (en) * 1996-09-25 1998-05-12 Sisti; Nicholas J. Method for paclitaxel synthesis
PT1178979E (pt) * 1999-05-17 2004-04-30 Bristol Myers Squibb Co Novas condicoes de reaccao para a clivagem de eteres de sililo na preparacao de paclitaxel (taxol(r)) e analogos de paclitaxel
JP2003522169A (ja) 2000-02-02 2003-07-22 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド 抗腫瘍剤としてのｃ７ヘテロ置換アセテートタキサン
HUP0200756A3 (en) 2000-02-02 2005-02-28 Univ Florida State Res Found C7 carbonate substituted taxanes as antitumor agents and pharmaceutical compositions containing them
US6452025B1 (en) 2001-04-25 2002-09-17 Napro Biotherapeutics, Inc. Three-step conversion of protected taxane ester to paclitaxel
US20050261367A1 (en) * 2004-03-29 2005-11-24 Howard Murad Methods for treating dermatological and other health-related conditions in a patient
CN100586940C (zh) * 2007-01-26 2010-02-03 上海百灵医药科技有限公司 紫杉醇和多烯紫杉醇的半合成方法
KR101014438B1 (ko) * 2008-09-26 2011-02-14 동아제약주식회사 탁산 유도체의 제조방법
PL388144A1 (pl) 2009-05-29 2010-12-06 Przedsiębiorstwo Produkcyjno-Wdrożeniowe Ifotam Spółka Z Ograniczoną Odpowiedzialnością Solwaty (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylopropionianu 4-acetoksy-2α-benzoiloksy -5β,20-epoksy-1,7β,10β-trihydroksy-9-okso-taks-11-en-13α-ylu, sposób ich otrzymywania i zastosowanie
US8829210B2 (en) * 2011-04-01 2014-09-09 Shilpa Medicare Limited Process for preparing docetaxel and its hydrate
KR101809858B1 (ko) 2012-04-04 2017-12-15 할로자임, 아이엔씨 항-히알루로난 제제 및 종양-표적 탁산을 이용한 병용 치료
EP2861256B1 (en) 2012-06-15 2019-10-23 The Brigham and Women's Hospital, Inc. Compositions for treating cancer and methods for making the same
CN106470681A (zh) 2014-04-03 2017-03-01 茵维特丝肿瘤学私营有限责任公司 超分子组合治疗药物
WO2019222435A1 (en) 2018-05-16 2019-11-21 Halozyme, Inc. Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR336841A (fr) 1903-10-29 1904-03-18 James William Mander Perfectionnements apportés aux instruments employés pour le dessin
FR336840A (fr) 1903-10-29 1904-03-18 Emmanuel Saura Machine à piston diviseur
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii

Also Published As

Publication number Publication date
US6596880B1 (en) 2003-07-22
WO1993016059A1 (fr) 1993-08-19
FR2687150A1 (fr) 1993-08-13
ES2090970T3 (es) 1996-10-16
FI943643A (fi) 1994-08-05
HU212577B (en) 1996-08-29
GR3020894T3 (en) 1996-11-30
DE69304309T2 (de) 1997-01-23
CA2126462C (fr) 2002-07-09
KR100254167B1 (ko) 2000-05-01
KR950700267A (ko) 1995-01-16
EP0625147B1 (fr) 1996-08-28
NZ249162A (en) 1996-10-28
CZ187094A3 (en) 1994-12-15
FI943643A0 (fi) 1994-08-05
DK0625147T3 (da) 1996-11-11
MX9300622A (es) 1993-08-01
ATE141920T1 (de) 1996-09-15
NO942895D0 (zh) 1994-08-04
SK280012B6 (sk) 1999-07-12
PL175106B1 (pl) 1998-11-30
RU94040356A (ru) 1997-05-27
EP0625147A1 (fr) 1994-11-23
CZ283377B6 (cs) 1998-04-15
JP3295879B2 (ja) 2002-06-24
RU2103266C1 (ru) 1998-01-27
AU686095B2 (en) 1998-02-05
ZA93823B (en) 1993-09-16
HU9402289D0 (en) 1994-10-28
AU3504893A (en) 1993-09-03
FR2687150B1 (fr) 1995-04-28
NO305863B1 (no) 1999-08-09
NO942895L (no) 1994-08-04
DE69304309D1 (de) 1996-10-02
SK93094A3 (en) 1995-04-12
CA2126462A1 (fr) 1993-08-19
HUT68773A (en) 1995-07-28
JPH07503472A (ja) 1995-04-13
FI106959B (fi) 2001-05-15

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Legal Events

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