ZA936127B - Crosslinked polymeric ammonium salts - Google Patents

Crosslinked polymeric ammonium salts

Info

Publication number
ZA936127B
ZA936127B ZA936127A ZA936127A ZA936127B ZA 936127 B ZA936127 B ZA 936127B ZA 936127 A ZA936127 A ZA 936127A ZA 936127 A ZA936127 A ZA 936127A ZA 936127 B ZA936127 B ZA 936127B
Authority
ZA
South Africa
Prior art keywords
pct
groups
atoms
ammonium
group
Prior art date
Application number
ZA936127A
Other languages
English (en)
Inventor
Garret Daniel Figuly
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of ZA936127B publication Critical patent/ZA936127B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0206—Polyalkylene(poly)amines
    • C08G73/0213—Preparatory process
    • C08G73/0226—Quaternisation of polyalkylene(poly)amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyethers (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Silicon Polymers (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Steroid Compounds (AREA)
ZA936127A 1992-08-20 1993-08-20 Crosslinked polymeric ammonium salts ZA936127B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93244992A 1992-08-20 1992-08-20

Publications (1)

Publication Number Publication Date
ZA936127B true ZA936127B (en) 1995-02-20

Family

ID=25462341

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA936127A ZA936127B (en) 1992-08-20 1993-08-20 Crosslinked polymeric ammonium salts

Country Status (23)

Country Link
US (2) US5633344A (hu)
EP (1) EP0656029B1 (hu)
JP (1) JPH08500386A (hu)
KR (1) KR950703016A (hu)
CN (1) CN1088223A (hu)
AT (1) ATE168707T1 (hu)
AU (1) AU672824B2 (hu)
CA (1) CA2142826A1 (hu)
CZ (1) CZ43995A3 (hu)
DE (1) DE69319914T2 (hu)
DK (1) DK0656029T3 (hu)
ES (1) ES2118254T3 (hu)
FI (1) FI950704A0 (hu)
GR (1) GR3027584T3 (hu)
HU (1) HUT72658A (hu)
IL (1) IL106733A (hu)
MX (1) MX9305077A (hu)
NZ (1) NZ255758A (hu)
PL (1) PL307527A1 (hu)
RU (1) RU95107405A (hu)
SK (1) SK31395A3 (hu)
WO (1) WO1994004596A1 (hu)
ZA (1) ZA936127B (hu)

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US6129910A (en) * 1993-06-02 2000-10-10 Geltex Pharmaceuticals, Inc. Water-insoluble noncrosslinked bile acid sequestrants
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5667775A (en) * 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5496545A (en) * 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
ZA95390B (en) * 1994-01-18 1996-07-18 Du Pont Crosslinked polymeric ammonium salts
TW474813B (en) 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
WO1996021454A1 (en) * 1995-01-12 1996-07-18 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US6203785B1 (en) 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US6423754B1 (en) 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
US6083497A (en) * 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
US6294163B1 (en) * 1998-10-02 2001-09-25 Geltex Pharmaceuticals, Inc. Polymers containing guanidinium groups as bile acid sequestrants
JP4854853B2 (ja) 1998-11-12 2012-01-18 ライフ テクノロジーズ コーポレーション トランスフェクション薬剤
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US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US6649187B2 (en) 2001-02-16 2003-11-18 Bristol-Myers Squibb Pharma Company Use of polyalkylamine polymers in controlled release devices
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JP2007526941A (ja) * 2004-02-23 2007-09-20 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー バイオマス由来材料を含有する架橋ポリマー
NO322564B1 (no) * 2004-03-22 2006-10-23 Ntnu Technology Transfer As Komposittmembran, fremgangsmate til fremstilling derav, samt anvendelse derav for separasjon av CO2 fra gassblandinger.
US8282960B2 (en) * 2004-03-30 2012-10-09 Relypsa, Inc. Ion binding compositions
US7854924B2 (en) * 2004-03-30 2010-12-21 Relypsa, Inc. Methods and compositions for treatment of ion imbalances
US8192758B2 (en) * 2004-03-30 2012-06-05 Relypsa, Inc. Ion binding compositions
US7429394B2 (en) * 2004-03-30 2008-09-30 Relypsa, Inc. Ion binding compositions
JP4974882B2 (ja) * 2004-03-30 2012-07-11 レリプサ， インコーポレイテッド イオン結合ポリマーとその利用
US7556799B2 (en) * 2004-03-30 2009-07-07 Relypsa, Inc. Ion binding polymers and uses thereof
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
CA2620406A1 (en) 2005-09-02 2007-03-08 Genzyme Corporation Method for removing phosphate and polymer used therefore
CA2622693C (en) 2005-09-15 2015-05-05 Genzyme Corporation Sachet formulation for amine polymers
BRPI0616604A2 (pt) 2005-09-30 2012-12-25 Ilypsa Inc mÉtodo para remover e composiÇço para seletivamente remover Íon de potÁssio do trato gastrintestinal de um mamÍfero, mÉtodo para seletivamente remover Íon de potÁssio de um meio-ambiente, composiÇço farmacÊutica, partÍcula de nécleo-envoltàrio, e, usos de uma partÍcula de nécleo-envoltàrio e de uma composiÇço farmacÊutica
BRPI0616603A2 (pt) * 2005-09-30 2012-12-25 Ilypsa Inc mÉtodo para preparar um compàsito de nécleo-envoltàrio, e para a manufatura de um medicamento, composiÇço farmacÊutica, e, uso da mesma
PT3431094T (pt) * 2008-08-22 2023-03-03 Vifor Int Ltd Polímeros reticulados de permuta catiónica, composições e uso no tratamento de hipercalemia
US20100104527A1 (en) * 2008-08-22 2010-04-29 Relypsa, Inc. Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties
US8337824B2 (en) 2008-08-22 2012-12-25 Relypsa, Inc. Linear polyol stabilized polyfluoroacrylate compositions
KR101822608B1 (ko) * 2010-02-24 2018-01-29 리립사, 인크. 담즙산 격리제로서 사용하기 위한 아민 폴리머
CN103958568B (zh) * 2011-11-25 2016-05-18 巴斯夫欧洲公司 通过均相催化醇胺化制备亲油性聚亚烷基多胺
WO2014058905A2 (en) 2012-10-08 2014-04-17 Relypsa, Inc. Potassium-binding agents for treating hypertension and hyperkalemia
CN103351444B (zh) * 2013-06-20 2015-04-15 山东诚创医药技术开发有限公司 包含n或氨基,铵或螺双环铵基团的交联聚合物凝胶的过滤洗涤方法
KR101631151B1 (ko) * 2014-05-22 2016-06-27 한국과학기술연구원 탄화수소계열 전해질 고분자 합성 방법 및 이에 사용되는 중합 용매
WO2016011203A1 (en) 2014-07-15 2016-01-21 Life Technologies Corporation Compositions with lipid aggregates and methods for efficient delivery of molecules to cells
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
CN107709477B (zh) 2015-04-30 2021-10-29 科慕埃弗西有限公司 包含可交联聚合物添加剂的耐久性建筑涂料
WO2022061279A1 (en) * 2020-09-21 2022-03-24 Stride Cross-linked polymeric ammonium salts and their use in absorbing organic contaminants
CN113583256B (zh) * 2021-07-05 2022-10-25 南京理工大学 一种阳离子水凝胶材料的制备方法

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BE467746A (hu) * 1945-09-15
US3383281A (en) * 1961-09-22 1968-05-14 Merck & Co Inc Method for binding bile acids in vivo
US3332841A (en) * 1961-10-04 1967-07-25 Lilly Co Eli Method of treating hyperacidity
US3803237A (en) * 1969-11-03 1974-04-09 Upjohn Co Reaction products of polyethylenepolyamines and chlorohydrins or epoxy containing compounds
US3692895A (en) * 1970-09-08 1972-09-19 Norman A Nelson Method of reducing hypercholesteremia in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance, such as epichlorohydria
US3980770A (en) * 1971-06-04 1976-09-14 Pharmacia Aktiebolag Polymerization products containing amino groups useful in serum cholesterol level control
US4027009A (en) * 1973-06-11 1977-05-31 Merck & Co., Inc. Compositions and methods for depressing blood serum cholesterol
US4205064A (en) * 1973-06-11 1980-05-27 Merck & Co., Inc. Bile acid sequestering composition containing poly[{alkyl-(3-ammoniopropyl)imino}-trimethylenedihalides]
US4147586A (en) * 1974-09-14 1979-04-03 Monsanto Company Cellulosic paper containing the reaction product of a dihaloalkane alkylene diamine adduct and epihalohydrin
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JPS5566513A (en) * 1978-11-14 1980-05-20 Ono Pharmaceut Co Ltd Drug for arteriosclerosis comprising high polymer compound as active constituent
US4374244A (en) * 1979-04-13 1983-02-15 Kewanee Industries, Inc. Linear quaternary ammonium polymers
JPS5879022A (ja) * 1981-11-04 1983-05-12 Bitamin Kenkyusho:Kk 第四級窒素原子を含有する新規な金属架橋高分子化合物、その製法及び該高分子化合物を有効成分とする高脂血症治療剤
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Also Published As

Publication number Publication date
US5667774A (en) 1997-09-16
CN1088223A (zh) 1994-06-22
IL106733A (en) 1998-06-15
ES2118254T3 (es) 1998-09-16
DE69319914T2 (de) 1999-01-21
SK31395A3 (en) 1995-08-09
HU9500475D0 (en) 1995-04-28
EP0656029A1 (en) 1995-06-07
WO1994004596A1 (en) 1994-03-03
AU5010993A (en) 1994-03-15
NZ255758A (en) 1997-10-24
IL106733A0 (en) 1993-12-08
CZ43995A3 (en) 1995-12-13
MX9305077A (es) 1994-06-30
KR950703016A (ko) 1995-08-23
PL307527A1 (en) 1995-05-29
AU672824B2 (en) 1996-10-17
RU95107405A (ru) 1997-02-10
FI950704A (fi) 1995-02-16
GR3027584T3 (en) 1998-11-30
CA2142826A1 (en) 1994-03-03
HUT72658A (en) 1996-05-28
ATE168707T1 (de) 1998-08-15
DK0656029T3 (da) 1999-02-15
EP0656029B1 (en) 1998-07-22
US5633344A (en) 1997-05-27
FI950704A0 (fi) 1995-02-16
JPH08500386A (ja) 1996-01-16
DE69319914D1 (de) 1998-08-27

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