ZA923176B - N-alkylenepiperidino compounds and their enantiomers,process for preparing them and pharmaceutical compositions containing them - Google Patents

N-alkylenepiperidino compounds and their enantiomers,process for preparing them and pharmaceutical compositions containing them

Info

Publication number
ZA923176B
ZA923176B ZA923176A ZA923176A ZA923176B ZA 923176 B ZA923176 B ZA 923176B ZA 923176 A ZA923176 A ZA 923176A ZA 923176 A ZA923176 A ZA 923176A ZA 923176 B ZA923176 B ZA 923176B
Authority
ZA
South Africa
Prior art keywords
group
alkyl
unsubstituted
carbon atoms
image
Prior art date
Application number
ZA923176A
Other languages
English (en)
Inventor
Xavier Emonds-Alt
Emonds-Alt Xavier
Serge Martinez
Martinez Serge
Vincenzo Proietto
Proietto Vincenzo
Didier Van Broeck
Van Broeck Didier
Original Assignee
Sanofi Elf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Elf filed Critical Sanofi Elf
Publication of ZA923176B publication Critical patent/ZA923176B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Control Of Transmission Device (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA923176A 1991-05-03 1992-04-30 N-alkylenepiperidino compounds and their enantiomers,process for preparing them and pharmaceutical compositions containing them ZA923176B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9105486A FR2676054B1 (fr) 1991-05-03 1991-05-03 Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.

Publications (1)

Publication Number Publication Date
ZA923176B true ZA923176B (en) 1993-04-28

Family

ID=9412519

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA923176A ZA923176B (en) 1991-05-03 1992-04-30 N-alkylenepiperidino compounds and their enantiomers,process for preparing them and pharmaceutical compositions containing them

Country Status (26)

Country Link
US (2) US5411971A (is)
EP (1) EP0515240B1 (is)
JP (1) JP3108719B2 (is)
KR (1) KR100244063B1 (is)
AT (1) ATE158574T1 (is)
AU (1) AU657321B2 (is)
BR (1) BR9201655A (is)
CA (1) CA2067924C (is)
CZ (1) CZ282919B6 (is)
DE (1) DE69222352T2 (is)
DK (1) DK0515240T3 (is)
ES (1) ES2109987T3 (is)
FI (1) FI103041B (is)
FR (1) FR2676054B1 (is)
GR (1) GR3025277T3 (is)
HU (1) HU213915B (is)
IE (1) IE921365A1 (is)
IL (1) IL101762A (is)
MX (1) MX9202026A (is)
MY (1) MY113018A (is)
NO (1) NO178572C (is)
NZ (1) NZ242584A (is)
RU (1) RU2089547C1 (is)
TW (1) TW201733B (is)
UA (1) UA26894C2 (is)
ZA (1) ZA923176B (is)

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US5512680A (en) 1993-02-26 1996-04-30 Sanofi Process for the preparation of an optically pure aminoalcohol
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GB9317104D0 (en) * 1993-08-17 1993-09-29 Zeneca Ltd Therapeutic heterocycles
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AU7947594A (en) * 1993-10-27 1995-05-22 Merck Sharp & Dohme Limited Substituted amides as tachykinin antagonists
GB9322643D0 (en) * 1993-11-03 1993-12-22 Zeneca Ltd Lactam derivatives
GB9325074D0 (en) * 1993-12-07 1994-02-02 Zeneca Ltd Bicyclic heterocycles
US5589489A (en) * 1993-12-15 1996-12-31 Zeneca Limited Cyclic amide derivatives for treating asthma
FR2719311B1 (fr) * 1994-03-18 1998-06-26 Sanofi Sa Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.
FR2717477B1 (fr) * 1994-03-18 1996-06-07 Sanofi Elf Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.
FR2717478B1 (fr) * 1994-03-18 1996-06-21 Sanofi Sa Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.
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GB9502644D0 (en) * 1995-02-10 1995-03-29 Zeneca Ltd Heterocyclic derivatives
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US5654316A (en) * 1995-06-06 1997-08-05 Schering Corporation Piperidine derivatives as neurokinin antagonists
GB9516709D0 (en) * 1995-08-15 1995-10-18 Zeneca Ltd Medicament
FR2738819B1 (fr) * 1995-09-14 1997-12-05 Sanofi Sa Nouveaux composes antagonistes selectifs du recepteur nk3 humain, procede pour leur obtention et compositions pharmaceutiques les contenant
GB9523526D0 (en) * 1995-11-17 1996-01-17 Zeneca Ltd Therapeutic compounds
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US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
NZ325581A (en) * 1995-12-20 2000-03-27 Hoechst Marion Roussel Inc Substituted 4-(1h-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
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US5998439A (en) 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
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FR2759585B1 (fr) * 1997-02-17 1999-06-11 Sanofi Sa Formulations pharmaceutiques presentees sous forme seche pour l'administration orale d'un compose ammonium quaternaire cyclique
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Also Published As

Publication number Publication date
JPH05140103A (ja) 1993-06-08
JP3108719B2 (ja) 2000-11-13
FR2676054B1 (fr) 1993-09-03
DK0515240T3 (da) 1998-05-11
EP0515240B1 (fr) 1997-09-24
KR100244063B1 (ko) 2000-03-02
CZ282919B6 (cs) 1997-11-12
IE921365A1 (en) 1992-11-04
BR9201655A (pt) 1992-12-15
NO921733L (no) 1992-11-04
EP0515240A1 (fr) 1992-11-25
US5606065A (en) 1997-02-25
NO921733D0 (no) 1992-04-30
ATE158574T1 (de) 1997-10-15
IL101762A (en) 1996-10-16
FI103041B1 (fi) 1999-04-15
HU9201459D0 (en) 1992-07-28
KR920021511A (ko) 1992-12-18
AU657321B2 (en) 1995-03-09
MX9202026A (es) 1992-11-01
AU1591892A (en) 1992-11-05
CA2067924C (en) 2004-03-30
TW201733B (is) 1993-03-11
NO178572B (no) 1996-01-15
NO178572C (no) 1996-04-24
DE69222352T2 (de) 1998-04-09
FI921950A (fi) 1992-11-04
IL101762A0 (en) 1992-12-30
FI921950A0 (fi) 1992-04-30
HU213915B (en) 1997-11-28
FR2676054A1 (fr) 1992-11-06
US5411971A (en) 1995-05-02
NZ242584A (en) 1995-04-27
GR3025277T3 (en) 1998-02-27
RU2089547C1 (ru) 1997-09-10
DE69222352D1 (de) 1997-10-30
FI103041B (fi) 1999-04-15
MY113018A (en) 2001-11-30
ES2109987T3 (es) 1998-02-01
CA2067924A1 (en) 1992-11-04
CS132892A3 (en) 1992-11-18
UA26894C2 (uk) 1999-12-29
HUT65273A (en) 1994-05-02

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