ZA897554B - New 2-carbonyl substituted n,n'-di-(trimethoxybenzoyl)piperazines,process for preparing the same and therapeutical compounds containing them - Google Patents

New 2-carbonyl substituted n,n'-di-(trimethoxybenzoyl)piperazines,process for preparing the same and therapeutical compounds containing them

Info

Publication number
ZA897554B
ZA897554B ZA897554A ZA897554A ZA897554B ZA 897554 B ZA897554 B ZA 897554B ZA 897554 A ZA897554 A ZA 897554A ZA 897554 A ZA897554 A ZA 897554A ZA 897554 B ZA897554 B ZA 897554B
Authority
ZA
South Africa
Prior art keywords
trimethoxybenzoyl
piperazines
preparing
new
same
Prior art date
Application number
ZA897554A
Other languages
English (en)
Inventor
Eduardo Pirotsky
Pirotsky Eduardo
Georges Dive
Dive Georges
Jean-Jacques Godfroid
Godfroid Jean-Jacques
Francoise Heymans
Heymans Francoise
Pierre Braquet
Braquet Pierre
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of ZA897554B publication Critical patent/ZA897554B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA897554A 1988-10-11 1989-10-04 New 2-carbonyl substituted n,n'-di-(trimethoxybenzoyl)piperazines,process for preparing the same and therapeutical compounds containing them ZA897554B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888823775A GB8823775D0 (en) 1988-10-11 1988-10-11 New 2-carbonyl substituted n n'-di-(trimethoxybenzoyl)piperazines

Publications (1)

Publication Number Publication Date
ZA897554B true ZA897554B (en) 1990-07-25

Family

ID=10644988

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA897554A ZA897554B (en) 1988-10-11 1989-10-04 New 2-carbonyl substituted n,n'-di-(trimethoxybenzoyl)piperazines,process for preparing the same and therapeutical compounds containing them

Country Status (33)

Country Link
US (1) US4923870A (da)
JP (1) JPH0635452B2 (da)
KR (1) KR970004912B1 (da)
AR (1) AR245110A1 (da)
AT (1) AT395423B (da)
AU (1) AU618220B2 (da)
BE (1) BE1003519A3 (da)
CA (1) CA1320958C (da)
CH (1) CH679859A5 (da)
DE (1) DE3933881C2 (da)
DK (1) DK500389A (da)
DZ (1) DZ1365A1 (da)
ES (1) ES2018403A6 (da)
FI (1) FI96854C (da)
FR (2) FR2637500B1 (da)
GB (2) GB8823775D0 (da)
GR (1) GR1000343B (da)
HK (1) HK47592A (da)
IE (1) IE62011B1 (da)
IN (1) IN173325B (da)
IT (1) IT1237088B (da)
LU (1) LU87604A1 (da)
MA (1) MA21652A1 (da)
MY (1) MY106235A (da)
NL (1) NL8902520A (da)
NO (1) NO176180C (da)
NZ (1) NZ230927A (da)
OA (1) OA09139A (da)
PT (1) PT91941B (da)
SE (1) SE505239C2 (da)
SG (1) SG41292G (da)
TN (1) TNSN89110A1 (da)
ZA (1) ZA897554B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8823776D0 (en) * 1988-10-11 1988-11-16 Scras New 2-methoxycarbonyl sustituted n n'-di-(trimethoxybenzoyl)piperazines
GB8908587D0 (en) * 1989-04-15 1989-06-01 Scras Societe De Conseils De R New 2-substituted n,n'-ditrimethoxybenzoyl piperazines
WO1992020661A1 (en) * 1991-05-22 1992-11-26 Merck & Co., Inc. N, n-diacylpiperazines
US5344830A (en) * 1992-12-10 1994-09-06 Merck & Co., Inc. N,N-diacylpiperazine tachykinin antagonists
US5348955A (en) * 1993-06-22 1994-09-20 Merck & Co., Inc. N,N-diacylpiperazines
FR2780649B1 (fr) 1998-07-06 2001-03-09 Univ Paris Vii Denis Diderot Derives de la piperazine pour l'inhibition de la replication du virus de l'immunodeficience humaine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3186993A (en) * 1962-06-07 1965-06-01 Ethyl Corp alpha, alpha'-(1, 4-piperazinediyl) bis (3, 5-dialkyl-4-hydroxythiobenzaldehyde) compounds
GB1243991A (en) * 1968-06-10 1971-08-25 Ici Ltd Piperidine, morpholine and piperazine derivatives
FR2209560A1 (en) * 1972-12-07 1974-07-05 Degussa N-(Trialkoxyaroyl)-ethylenediamine derivs - useful as cardioactive medicaments, exhibit anti-ischaemic activity comparable to nitroglycerin
DE2423847A1 (de) * 1973-05-28 1975-01-02 Ciba Geigy Ag Neue sulfamoylbenzoesaeureamide
GB8427735D0 (en) * 1984-11-02 1984-12-12 Fujisawa Pharmaceutical Co Piperazine compound
FR2581993B1 (fr) * 1985-05-14 1988-03-18 Synthelabo Derives de (benzoyl-4 piperidino)-2 phenyl-1 alcanols, leur preparation et leur application en therapeutique
DE3636278A1 (de) * 1986-10-24 1988-05-05 Hoechst Ag Herbizide mittel auf der basis von cyclischen (alpha)-iminocarbon-saeureaniliden sowie neue (alpha)-iminocarbonsaeureanilide und verfahren zu ihrer herstellung
IL85700A0 (en) * 1987-03-24 1988-08-31 Takeda Chemical Industries Ltd 1,4-disubstituted piperazine compounds,their production and use
GB8823776D0 (en) * 1988-10-11 1988-11-16 Scras New 2-methoxycarbonyl sustituted n n'-di-(trimethoxybenzoyl)piperazines
US4997836A (en) * 1988-11-11 1991-03-05 Takeda Chemical Industries, Ltd. Trisubstituted piperazine compounds, their production and use

Also Published As

Publication number Publication date
SG41292G (en) 1992-06-12
TNSN89110A1 (fr) 1991-02-04
GB8823775D0 (en) 1988-11-16
FI894812A0 (fi) 1989-10-11
FR2637500A1 (fr) 1990-04-13
AT395423B (de) 1992-12-28
GR890100647A (en) 1990-11-29
NO176180B (no) 1994-11-07
JPH0635452B2 (ja) 1994-05-11
GB8922870D0 (en) 1989-11-29
CA1320958C (en) 1993-08-03
CH679859A5 (da) 1992-04-30
NO894038D0 (no) 1989-10-10
IT8921992A1 (it) 1991-04-11
SE8903312L (sv) 1990-04-12
DK500389D0 (da) 1989-10-10
NZ230927A (en) 1991-01-29
FI96854C (fi) 1996-09-10
FR2637500B1 (fr) 1992-06-05
GR1000343B (el) 1992-06-25
DK500389A (da) 1990-04-12
IT8921992A0 (it) 1989-10-11
GB2223753A (en) 1990-04-18
NO894038L (no) 1990-04-17
SE8903312D0 (sv) 1989-10-09
NL8902520A (nl) 1990-05-01
KR970004912B1 (ko) 1997-04-08
FI894812A (fi) 1990-04-12
PT91941A (pt) 1990-04-30
BE1003519A3 (fr) 1992-04-14
HK47592A (en) 1992-07-10
OA09139A (fr) 1991-10-31
MY106235A (en) 1995-04-29
LU87604A1 (fr) 1990-02-07
AU4268889A (en) 1990-04-26
AR245110A1 (es) 1993-12-30
DZ1365A1 (fr) 2004-09-13
IE62011B1 (en) 1994-12-14
GB2223753B (en) 1992-01-02
FR2637593A1 (fr) 1990-04-13
US4923870A (en) 1990-05-08
NO176180C (no) 1995-02-15
DE3933881A1 (de) 1990-04-12
IE893258L (en) 1990-04-11
IT1237088B (it) 1993-05-18
FI96854B (fi) 1996-05-31
SE505239C2 (sv) 1997-07-21
MA21652A1 (fr) 1990-07-01
ATA234689A (de) 1992-05-15
ES2018403A6 (es) 1991-04-01
IN173325B (da) 1994-04-02
PT91941B (pt) 1995-05-31
DE3933881C2 (de) 1994-06-30
KR900006309A (ko) 1990-05-07
AU618220B2 (en) 1991-12-12
JPH02223565A (ja) 1990-09-05
FR2637593B1 (fr) 1992-06-05

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