ZA895661B - Human nerve growth factor - Google Patents
Human nerve growth factorInfo
- Publication number
- ZA895661B ZA895661B ZA895661A ZA895661A ZA895661B ZA 895661 B ZA895661 B ZA 895661B ZA 895661 A ZA895661 A ZA 895661A ZA 895661 A ZA895661 A ZA 895661A ZA 895661 B ZA895661 B ZA 895661B
- Authority
- ZA
- South Africa
- Prior art keywords
- growth factor
- nerve growth
- human nerve
- hngf
- biologically active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/48—Nerve growth factor [NGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27487888A | 1988-11-22 | 1988-11-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA895661B true ZA895661B (en) | 1991-04-24 |
Family
ID=23049976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA895661A ZA895661B (en) | 1988-11-22 | 1989-07-25 | Human nerve growth factor |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5272063A (de) |
| EP (2) | EP0859056A3 (de) |
| JP (3) | JP2515399B2 (de) |
| KR (1) | KR100225052B1 (de) |
| AT (1) | ATE167701T1 (de) |
| AU (1) | AU629840B2 (de) |
| CA (1) | CA1341131C (de) |
| DE (1) | DE68928718T2 (de) |
| DK (1) | DK175764B1 (de) |
| ES (1) | ES2118057T3 (de) |
| IE (2) | IE980253A1 (de) |
| NZ (1) | NZ230096A (de) |
| ZA (1) | ZA895661B (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5130298A (en) * | 1989-05-16 | 1992-07-14 | Ethicon, Inc. | Stabilized compositions containing epidermal growth factor |
| US5180820A (en) * | 1989-08-30 | 1993-01-19 | Barde Yves Alain | Brain-derived neurotrophic factor |
| IT1238348B (it) * | 1989-11-16 | 1993-07-13 | Processo per la preparazione di costrutti genetici per l'espressione del fattore di crescita nervoso in cellule eucariote. | |
| IT1239271B (it) * | 1990-02-27 | 1993-10-01 | Fidia Spa | Processo per l'espressione del fattore di crescita nervoso umano in cellule di artropoda frugiperda via infezione con baculovirus ricombinante |
| US5389529A (en) * | 1991-06-12 | 1995-02-14 | Regeneron Pharmaceuticals, Inc. | Modified lamβ signal sequence and processes for producing recombinant neurotrophins |
| US5317097A (en) * | 1991-10-07 | 1994-05-31 | The Research Foundation Of State University Of New York | Mutations in the gene encoding the α chain on platelet glycoprotein IB |
| US5298239A (en) * | 1991-10-07 | 1994-03-29 | The Research Foundation Of State University Of New York | Mutations rendering platelet glycoprotein IB α less reactive |
| DE4139000A1 (de) * | 1991-11-27 | 1993-06-03 | Boehringer Mannheim Gmbh | Verfahren zur gentechnologischen herstellung von biologisch aktivem ss-ngf |
| ATE206056T1 (de) * | 1992-06-08 | 2001-10-15 | Takeda Chemical Industries Ltd | Therapeutisches agens für neutropenie |
| CA2104418A1 (en) * | 1992-08-24 | 1994-02-25 | Miguel A. Maestro | Method of preparing hydrindane compounds and hydrindane-related compounds |
| US5859311A (en) * | 1995-11-27 | 1999-01-12 | University Of Kentucky Research Foundation | Transgenic mice which overexpress neurotrophin-3 (NT-3) and methods of use |
| NZ335207A (en) * | 1996-11-15 | 2000-09-29 | Genentech Inc | Process to isolate recombinant human neurotrophin using hydrophobic chromatography resin |
| US6245564B1 (en) | 1997-01-23 | 2001-06-12 | Cornell Research Foundation, Inc. | Method for separating cells |
| US8263402B1 (en) | 1998-10-19 | 2012-09-11 | Cornell Research Foundation, Inc. | Method for isolating and purifying oligodendrocytes and oligodendrocyte progenitor cells |
| US20030211088A1 (en) * | 2001-03-12 | 2003-11-13 | Field Loren J. | Multipotent cell and cardiomyocyte cell populations, and routes to and uses of same |
| AU2002327433A1 (en) * | 2001-08-10 | 2003-02-24 | Cornell Research Foundation, Inc. | Telomerase immortalized human neutral stem cells and phenotypically-restricted progenitor cells |
| AU2003210959A1 (en) * | 2002-02-12 | 2003-09-04 | Cornell Research Foundation, Inc. | Identification and high-yield isolation of human pancreatic islet progenitor and stem cells |
| JP5918697B2 (ja) | 2010-10-15 | 2016-05-18 | Ｊｃｒファーマ株式会社 | 糖鎖の非還元末端がマンノース残基である糖蛋白質の製造方法 |
| CN108456681B (zh) * | 2018-03-26 | 2019-10-11 | 江苏中新医药有限公司 | 高效表达重组人神经生长因子的基因组合 |
| CN109628487A (zh) * | 2018-12-21 | 2019-04-16 | 华南农业大学 | 一种利用转基因猪唾液腺制备人神经生长因子的方法 |
| CN111500641A (zh) * | 2020-05-13 | 2020-08-07 | 华南农业大学 | 转人神经生长因子基因猪的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK161152C (da) * | 1983-03-03 | 1991-11-11 | Genentech Inc | Polypeptid med egenskaber som human beta-nervevaekstfaktor og fremgangsmaade til fremstilling deraf, dna-isolat omfattende en sekvens som koder for polypeptidet, replicerbar udtrykkelsesvektor for dna-sekvensen, rekombinant vaertscelle transformeret med vektoren, farmaceutisk praeparat indeholdende polypeptidet og fremg. der omfatter anvendelsen af polypeptidet til fremst. af et farmaceutisk praeparat |
| US4745051A (en) * | 1983-05-27 | 1988-05-17 | The Texas A&M University System | Method for producing a recombinant baculovirus expression vector |
| DE3485810T2 (de) * | 1983-05-27 | 1992-12-10 | Texas A & M University Syst | Verfahren zur herstellung eines rekombinanten baculovirus-expressionsvektors. |
| JPS61205485A (ja) * | 1985-03-09 | 1986-09-11 | Eiko Otsuka | ヒト神経成長因子遺伝子セグメント |
| JPS63167797A (ja) * | 1985-12-18 | 1988-07-11 | マイクロジエネシス，インコ−ポレイテイド | 選択された昆虫宿主細胞中で選択されたポリペプチドを製造する方法 |
| ES2008204A6 (es) * | 1986-09-09 | 1989-07-16 | Genetics Inst | Metodos para producir cuerpos de inclusion polihedrica de composicion mezclada (pib),para coinfectar insectos huespedes y para producir proteinas heterologas en insectos. |
| US5024947A (en) * | 1987-07-24 | 1991-06-18 | Cetus Corporation | Serum free media for the growth on insect cells and expression of products thereby |
| US5082774A (en) * | 1988-08-30 | 1992-01-21 | The General Hospital Corporation | Recombinant human nerve growth factor |
-
1989
- 1989-07-20 US US07/383,118 patent/US5272063A/en not_active Expired - Lifetime
- 1989-07-25 EP EP98102111A patent/EP0859056A3/de not_active Ceased
- 1989-07-25 DE DE68928718T patent/DE68928718T2/de not_active Expired - Fee Related
- 1989-07-25 DK DK198903667A patent/DK175764B1/da not_active IP Right Cessation
- 1989-07-25 AT AT89113709T patent/ATE167701T1/de not_active IP Right Cessation
- 1989-07-25 ZA ZA895661A patent/ZA895661B/xx unknown
- 1989-07-25 EP EP89113709A patent/EP0370171B1/de not_active Expired - Lifetime
- 1989-07-25 ES ES89113709T patent/ES2118057T3/es not_active Expired - Lifetime
- 1989-07-26 IE IE19980253A patent/IE980253A1/en not_active IP Right Cessation
- 1989-07-26 NZ NZ230096A patent/NZ230096A/en unknown
- 1989-07-26 IE IE242589A patent/IE81110B1/en not_active IP Right Cessation
- 1989-07-27 AU AU39009/89A patent/AU629840B2/en not_active Ceased
- 1989-07-28 CA CA000607007A patent/CA1341131C/en not_active Expired - Fee Related
- 1989-07-28 KR KR1019890010831A patent/KR100225052B1/ko not_active IP Right Cessation
- 1989-07-28 JP JP1196431A patent/JP2515399B2/ja not_active Expired - Fee Related
-
1994
- 1994-07-25 JP JP6172189A patent/JP2732556B2/ja not_active Expired - Fee Related
-
1997
- 1997-02-20 JP JP9036733A patent/JPH09235299A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPH09235299A (ja) | 1997-09-09 |
| DK366789A (da) | 1990-05-23 |
| DK366789D0 (da) | 1989-07-25 |
| JPH07247300A (ja) | 1995-09-26 |
| ATE167701T1 (de) | 1998-07-15 |
| AU3900989A (en) | 1990-05-31 |
| DE68928718D1 (de) | 1998-07-30 |
| JP2732556B2 (ja) | 1998-03-30 |
| EP0370171B1 (de) | 1998-06-24 |
| NZ230096A (en) | 1992-08-26 |
| CA1341131C (en) | 2000-10-31 |
| IE980253A1 (en) | 2000-02-23 |
| AU629840B2 (en) | 1992-10-15 |
| IE892425L (en) | 1990-05-22 |
| JP2515399B2 (ja) | 1996-07-10 |
| EP0370171A2 (de) | 1990-05-30 |
| JPH02291270A (ja) | 1990-12-03 |
| US5272063A (en) | 1993-12-21 |
| DK175764B1 (da) | 2005-02-14 |
| EP0859056A2 (de) | 1998-08-19 |
| KR100225052B1 (ko) | 1999-10-15 |
| EP0859056A3 (de) | 1999-03-24 |
| KR900008039A (ko) | 1990-06-02 |
| DE68928718T2 (de) | 1998-10-29 |
| ES2118057T3 (es) | 1998-09-16 |
| EP0370171A3 (de) | 1990-08-29 |
| IE81110B1 (en) | 2000-03-08 |
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