ZA894533B - Neurokinin a antogonists - Google Patents

Neurokinin a antogonists

Info

Publication number
ZA894533B
ZA894533B ZA894533A ZA894533A ZA894533B ZA 894533 B ZA894533 B ZA 894533B ZA 894533 A ZA894533 A ZA 894533A ZA 894533 A ZA894533 A ZA 894533A ZA 894533 B ZA894533 B ZA 894533B
Authority
ZA
South Africa
Prior art keywords
antogonists
neurokinin
Prior art date
Application number
ZA894533A
Other languages
English (en)
Inventor
Stephen Henderson Buck
Henderson Buck Stephen
John Leonard Krstenansky
Leonard Krstenansky John
Chester Fred Hassmann Iii
Fred Hassmann Chester Iii
James Ray Mccarthy
Ray Mccarthy James
Scott Lee Harbeson
Lee Harbeson Scott
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA894533B publication Critical patent/ZA894533B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02Linear peptides containing at least one abnormal peptide link
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0212Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/22Tachykinins, e.g. Eledoisins, Substance P; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ZA894533A 1988-06-20 1989-06-14 Neurokinin a antogonists ZA894533B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20892688A 1988-06-20 1988-06-20

Publications (1)

Publication Number Publication Date
ZA894533B true ZA894533B (en) 1990-03-28

Family

ID=22776618

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA894533A ZA894533B (en) 1988-06-20 1989-06-14 Neurokinin a antogonists

Country Status (19)

Country Link
EP (1) EP0347802B1 (de)
JP (1) JP2711720B2 (de)
KR (1) KR0136605B1 (de)
CN (1) CN1030703C (de)
AR (1) AR246085A1 (de)
AT (1) ATE107312T1 (de)
AU (1) AU619857B2 (de)
CA (1) CA1340824C (de)
DE (1) DE68916113T2 (de)
DK (1) DK174964B1 (de)
ES (1) ES2057024T3 (de)
FI (1) FI94351C (de)
HU (1) HU204850B (de)
IE (1) IE61362B1 (de)
IL (1) IL90637A (de)
NO (1) NO176105C (de)
NZ (1) NZ229552A (de)
PT (1) PT90902B (de)
ZA (1) ZA894533B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877277A (en) 1987-09-24 1999-03-02 Biomeasure, Inc. Octapeptide bombesin analogs
AU638264B2 (en) * 1989-08-10 1993-06-24 Aventis Inc. Cyclic neurokinin a antagonists
IE77033B1 (en) * 1989-08-16 1997-11-19 Univ Tulane Substance P antagonists
FR2666335B1 (fr) 1990-09-05 1992-12-11 Sanofi Sa Arylalkylamines, procede pour leur preparation et compositions pharmaceutiques les contenant.
JPH06507174A (ja) * 1991-04-22 1994-08-11 マリンクロッド・メディカル・インコーポレイテッド ニューロキニン1レセプターを有する組織を検出および局部化する方法
US5625060A (en) * 1991-05-03 1997-04-29 Elf Sanofi Polycyclic amine compounds and their enantiomers, their method of preparation and pharmaceutical compositions on which they are present
FR2676055B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
ES2106188T3 (es) * 1991-05-23 1997-11-01 Merrell Pharma Inc Analogos de bombesina.
GB9727123D0 (en) * 1997-12-22 1998-02-25 Int Centre Genetic Eng & Bio Synthesis of diamines
JP2000021345A (ja) 1998-07-06 2000-01-21 Hitachi Ltd 走査型電子顕微鏡

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1302926C (en) * 1986-03-04 1992-06-09 Hideo Sugawara Antibiotic f-0769, process for its production, and its use as a growthaccelerating and feed efficiency increasing agent and as an antitumour agent
IT1233696B (it) * 1989-05-29 1992-04-14 Menarini Farma Ind Peptidi di sintesi antagonisti della neurochinina a. loro sali e relativi procedimenti di fabbricazione
AU638264B2 (en) * 1989-08-10 1993-06-24 Aventis Inc. Cyclic neurokinin a antagonists

Also Published As

Publication number Publication date
IL90637A (en) 1993-07-08
ES2057024T3 (es) 1994-10-16
FI893002A (fi) 1989-12-21
NZ229552A (en) 1992-06-25
HU204850B (en) 1992-02-28
FI94351B (fi) 1995-05-15
IE61362B1 (en) 1994-11-02
FI893002A0 (fi) 1989-06-19
DK174964B1 (da) 2004-04-05
EP0347802A3 (de) 1991-07-17
DK301889A (da) 1989-12-21
AU619857B2 (en) 1992-02-06
HUT50196A (en) 1989-12-28
AR246085A1 (es) 1994-03-30
CN1039597A (zh) 1990-02-14
CN1030703C (zh) 1996-01-17
NO176105B (no) 1994-10-24
DE68916113D1 (de) 1994-07-21
JP2711720B2 (ja) 1998-02-10
KR910000791A (ko) 1991-01-30
PT90902A (pt) 1989-12-29
NO892542L (no) 1989-12-21
FI94351C (fi) 1995-08-25
EP0347802B1 (de) 1994-06-15
DK301889D0 (da) 1989-06-19
EP0347802A2 (de) 1989-12-27
KR0136605B1 (ko) 1998-04-25
CA1340824C (en) 1999-11-16
NO176105C (no) 1995-02-01
IL90637A0 (en) 1990-01-18
IE891987L (en) 1989-12-20
JPH0245497A (ja) 1990-02-15
PT90902B (pt) 1994-12-30
DE68916113T2 (de) 1994-09-22
NO892542D0 (no) 1989-06-19
AU3652389A (en) 1989-12-21
ATE107312T1 (de) 1994-07-15

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