ZA884920B - Novel 3,5-dihydroxycarboxylic acids and their derivatives,process for their preparation,their use as medicines,pharmaceutical products and intermediate products - Google Patents

Novel 3,5-dihydroxycarboxylic acids and their derivatives,process for their preparation,their use as medicines,pharmaceutical products and intermediate products

Info

Publication number
ZA884920B
ZA884920B ZA884920A ZA884920A ZA884920B ZA 884920 B ZA884920 B ZA 884920B ZA 884920 A ZA884920 A ZA 884920A ZA 884920 A ZA884920 A ZA 884920A ZA 884920 B ZA884920 B ZA 884920B
Authority
ZA
South Africa
Prior art keywords
alkyl
opt
substd
cpds
formula
Prior art date
Application number
ZA884920A
Other languages
English (en)
Inventor
Wess Guenther
Granzer Ernold
Bartmann Wilhelm
Beck Gerhard
Original Assignee
Hoechst Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Aktiengesellschaft filed Critical Hoechst Aktiengesellschaft
Publication of ZA884920B publication Critical patent/ZA884920B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C07C33/48—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts with unsaturation outside the aromatic rings
    • C07C33/486—Polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
ZA884920A 1987-07-10 1988-07-08 Novel 3,5-dihydroxycarboxylic acids and their derivatives,process for their preparation,their use as medicines,pharmaceutical products and intermediate products ZA884920B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873722807 DE3722807A1 (de) 1987-07-10 1987-07-10 Neue 3,5-dihydroxycarbonsaeuren und deren derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte

Publications (1)

Publication Number Publication Date
ZA884920B true ZA884920B (en) 1989-01-17

Family

ID=6331292

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA884920A ZA884920B (en) 1987-07-10 1988-07-08 Novel 3,5-dihydroxycarboxylic acids and their derivatives,process for their preparation,their use as medicines,pharmaceutical products and intermediate products

Country Status (17)

Country Link
EP (1) EP0306649B1 (no)
JP (1) JPS6445337A (no)
KR (1) KR890001941A (no)
AT (1) ATE73123T1 (no)
AU (1) AU606712B2 (no)
DE (2) DE3722807A1 (no)
DK (1) DK383988A (no)
ES (1) ES2031959T3 (no)
FI (1) FI90412C (no)
GR (1) GR3004588T3 (no)
HU (1) HU199768B (no)
IL (1) IL87035A0 (no)
NO (1) NO167795C (no)
NZ (1) NZ225343A (no)
PH (1) PH27496A (no)
PT (1) PT87928B (no)
ZA (1) ZA884920B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989003212A1 (en) * 1987-10-13 1989-04-20 Pfizer Inc. 3,5-dihydroxy-6,8-nonadienoic acids and derivatives as hypocholesterolemic agents
DE3826814A1 (de) * 1988-08-06 1990-02-08 Hoechst Ag Neue 6-fluor-3,5-dihydroxycarbonsaeuren und deren derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
DE3832570A1 (de) * 1988-09-24 1990-03-29 Hoechst Ag 7-substituierte derivate der 3,5-dihydroxyhept-6-insaeure, verfahren zur ihrer herstellung, ihre verwendung als arzneimittel, sowie zwischenprodukte
EP0430129A3 (en) * 1989-11-30 1992-02-26 Tanabe Seiyaku Co., Ltd. Novel phenylethylene derivatives, processes for preparing the same and intermediates therefor
EP0554455B1 (en) * 1991-06-19 1997-12-17 Shionogi Seiyaku Kabushiki Kaisha Optically active intermediate and production thereof
CN1780811A (zh) * 2003-03-05 2006-05-31 细胞基因公司 二苯基乙烯化合物及其用途
EP2072729B1 (en) * 2007-12-21 2013-06-26 IVECO S.p.A. Hinge for vehicle door, in particular of a van

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL102791C (no) * 1957-08-01
NL295084A (no) * 1962-07-11 1900-01-01
US3919304A (en) * 1968-10-25 1975-11-11 Ciba Geigy Corp {62 -Hydroxy-{62 -(cycloalkenylphenyl)alkanoic acids, esters and salts
BE793686A (fr) * 1972-01-07 1973-07-04 Beecham Group Ltd Composes di-aryliques biologiquement actifs
DE2212948A1 (de) * 1972-03-17 1973-09-20 Basf Ag Verfahren zur herstellung von in alpha-stellung verzweigten alpha,betaungesaettigten aldehyden
JPS5559140A (en) * 1978-10-30 1980-05-02 Sankyo Co Ltd 3,5-dihydroxypentanoic alkyl ester derivative, its preparation and remedy for hyperlipemia containing the same as the effective component
US4341910A (en) * 1979-01-25 1982-07-27 Texas Alkyls, Inc. Preparation of unsaturated alcohols
US4567289A (en) * 1979-08-17 1986-01-28 Merck & Co., Inc. Substituted pyranone inhibitors of cholesterol synthesis
US4459422A (en) * 1979-08-17 1984-07-10 Merck & Co., Inc. Substituted pyranone inhibitors of cholesterol synthesis
DE2934251A1 (de) * 1979-08-24 1981-03-26 Basf Ag, 67063 Ludwigshafen Verfahren zur herstellung von ungesaettigten alkoholen.
EP0040177B1 (de) * 1980-05-13 1983-07-20 Ciba-Geigy Ag Verfahren zur Herstellung von Alkenylbenzol- oder -naphthalincarbonsäurederivaten
FI77839C (fi) * 1982-05-27 1989-05-10 Farmos Oy Foerfarande foer framstaellning av nya terapeutiskt effektiva trifenylalkan- och alkenderivat.
JPS59163336A (ja) * 1983-03-09 1984-09-14 Nippon Petrochem Co Ltd アルデヒドの製造法
NL8502010A (nl) * 1984-07-24 1986-02-17 Sandoz Ag Nafthylanaloga van mevalonolacton en derivaten daarvan, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten.
DE3523181A1 (de) * 1985-06-28 1987-01-08 Basf Ag Verfahren zur herstellung von 2-methyl-2-alkenalen
US4611081A (en) * 1985-07-05 1986-09-09 Merck & Co., Inc. Process for the preparation of HMG-CoA reductase inhibitors intermediates
US4745229A (en) * 1986-02-28 1988-05-17 Kuraray Company Ltd. Process for preparing α, β-unsaturated aldehydes

Also Published As

Publication number Publication date
DE3722807A1 (de) 1989-01-19
ATE73123T1 (de) 1992-03-15
DE3868794D1 (de) 1992-04-09
FI90412C (fi) 1994-02-10
NO167795B (no) 1991-09-02
PT87928A (pt) 1989-06-30
FI90412B (fi) 1993-10-29
ES2031959T3 (es) 1993-01-01
IL87035A0 (en) 1988-12-30
FI883248A (fi) 1989-01-11
NO883071L (no) 1989-01-11
EP0306649A1 (de) 1989-03-15
DK383988D0 (da) 1988-07-08
PT87928B (pt) 1995-05-04
GR3004588T3 (no) 1993-04-28
HU199768B (en) 1990-03-28
KR890001941A (ko) 1989-04-06
FI883248A0 (fi) 1988-07-07
NZ225343A (en) 1991-02-26
PH27496A (en) 1993-07-23
JPS6445337A (en) 1989-02-17
NO883071D0 (no) 1988-07-08
AU606712B2 (en) 1991-02-14
AU1888188A (en) 1989-01-12
EP0306649B1 (de) 1992-03-04
HUT47237A (en) 1989-02-28
DK383988A (da) 1989-01-11
NO167795C (no) 1991-12-11

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