FI883248A - Menetelmä terapeuttisesti käyttökelpoisten 3,5-dihydroksikarboksyylihappojohdannaisten valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten 3,5-dihydroksikarboksyylihappojohdannaisten valmistamiseksi Download PDF

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Publication number
FI883248A
FI883248A FI883248A FI883248A FI883248A FI 883248 A FI883248 A FI 883248A FI 883248 A FI883248 A FI 883248A FI 883248 A FI883248 A FI 883248A FI 883248 A FI883248 A FI 883248A
Authority
FI
Finland
Prior art keywords
alkyl
opt
substd
cpds
formula
Prior art date
Application number
FI883248A
Other languages
English (en)
Swedish (sv)
Other versions
FI883248A0 (fi
FI90412C (fi
FI90412B (fi
Inventor
Guenther Wess
Wilhelm Bartmann
Gerhard Beck
Ernold Granzer
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI883248A0 publication Critical patent/FI883248A0/fi
Publication of FI883248A publication Critical patent/FI883248A/fi
Application granted granted Critical
Publication of FI90412B publication Critical patent/FI90412B/fi
Publication of FI90412C publication Critical patent/FI90412C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40Halogenated unsaturated alcohols
    • C07C33/46Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C07C33/48Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts with unsaturation outside the aromatic rings
    • C07C33/486Polycyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
FI883248A 1987-07-10 1988-07-07 Menetelmä terapeuttisesti käyttökelpoisten 3,5-dihydroksikarboksyylihappojohdannaisten valmistamiseksi FI90412C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3722807 1987-07-10
DE19873722807 DE3722807A1 (de) 1987-07-10 1987-07-10 Neue 3,5-dihydroxycarbonsaeuren und deren derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte

Publications (4)

Publication Number Publication Date
FI883248A0 FI883248A0 (fi) 1988-07-07
FI883248A true FI883248A (fi) 1989-01-11
FI90412B FI90412B (fi) 1993-10-29
FI90412C FI90412C (fi) 1994-02-10

Family

ID=6331292

Family Applications (1)

Application Number Title Priority Date Filing Date
FI883248A FI90412C (fi) 1987-07-10 1988-07-07 Menetelmä terapeuttisesti käyttökelpoisten 3,5-dihydroksikarboksyylihappojohdannaisten valmistamiseksi

Country Status (17)

Country Link
EP (1) EP0306649B1 (fi)
JP (1) JPS6445337A (fi)
KR (1) KR890001941A (fi)
AT (1) ATE73123T1 (fi)
AU (1) AU606712B2 (fi)
DE (2) DE3722807A1 (fi)
DK (1) DK383988A (fi)
ES (1) ES2031959T3 (fi)
FI (1) FI90412C (fi)
GR (1) GR3004588T3 (fi)
HU (1) HU199768B (fi)
IL (1) IL87035A0 (fi)
NO (1) NO167795C (fi)
NZ (1) NZ225343A (fi)
PH (1) PH27496A (fi)
PT (1) PT87928B (fi)
ZA (1) ZA884920B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989003212A1 (en) * 1987-10-13 1989-04-20 Pfizer Inc. 3,5-dihydroxy-6,8-nonadienoic acids and derivatives as hypocholesterolemic agents
DE3826814A1 (de) * 1988-08-06 1990-02-08 Hoechst Ag Neue 6-fluor-3,5-dihydroxycarbonsaeuren und deren derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
DE3832570A1 (de) * 1988-09-24 1990-03-29 Hoechst Ag 7-substituierte derivate der 3,5-dihydroxyhept-6-insaeure, verfahren zur ihrer herstellung, ihre verwendung als arzneimittel, sowie zwischenprodukte
EP0430129A3 (en) * 1989-11-30 1992-02-26 Tanabe Seiyaku Co., Ltd. Novel phenylethylene derivatives, processes for preparing the same and intermediates therefor
ATE161262T1 (de) * 1991-06-19 1998-01-15 Shionogi & Co Optisch aktives zwischenprodukt und dessen herstellung
EP1603864A4 (en) * 2003-03-05 2007-04-11 Celgene Corp DIPHENYLETHYLENE COMPOUNDS AND THEIR USE
EP2072729B1 (en) * 2007-12-21 2013-06-26 IVECO S.p.A. Hinge for vehicle door, in particular of a van

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL230107A (fi) * 1957-08-01
NL295084A (fi) * 1962-07-11 1900-01-01
US3919304A (en) * 1968-10-25 1975-11-11 Ciba Geigy Corp {62 -Hydroxy-{62 -(cycloalkenylphenyl)alkanoic acids, esters and salts
BE793686A (fr) * 1972-01-07 1973-07-04 Beecham Group Ltd Composes di-aryliques biologiquement actifs
DE2212948A1 (de) * 1972-03-17 1973-09-20 Basf Ag Verfahren zur herstellung von in alpha-stellung verzweigten alpha,betaungesaettigten aldehyden
JPS5559140A (en) * 1978-10-30 1980-05-02 Sankyo Co Ltd 3,5-dihydroxypentanoic alkyl ester derivative, its preparation and remedy for hyperlipemia containing the same as the effective component
US4341910A (en) * 1979-01-25 1982-07-27 Texas Alkyls, Inc. Preparation of unsaturated alcohols
US4567289A (en) * 1979-08-17 1986-01-28 Merck & Co., Inc. Substituted pyranone inhibitors of cholesterol synthesis
US4459422A (en) * 1979-08-17 1984-07-10 Merck & Co., Inc. Substituted pyranone inhibitors of cholesterol synthesis
DE2934251A1 (de) * 1979-08-24 1981-03-26 Basf Ag, 67063 Ludwigshafen Verfahren zur herstellung von ungesaettigten alkoholen.
EP0040177B1 (de) * 1980-05-13 1983-07-20 Ciba-Geigy Ag Verfahren zur Herstellung von Alkenylbenzol- oder -naphthalincarbonsäurederivaten
FI77839C (fi) * 1982-05-27 1989-05-10 Farmos Oy Foerfarande foer framstaellning av nya terapeutiskt effektiva trifenylalkan- och alkenderivat.
JPS59163336A (ja) * 1983-03-09 1984-09-14 Nippon Petrochem Co Ltd アルデヒドの製造法
HUT39142A (en) * 1984-07-24 1986-08-28 Sandoz Ag Process for producing naphtyl-analogues of mevalolactone and derivatives and pharmaceutical compositions containing them
DE3523181A1 (de) * 1985-06-28 1987-01-08 Basf Ag Verfahren zur herstellung von 2-methyl-2-alkenalen
US4611081A (en) * 1985-07-05 1986-09-09 Merck & Co., Inc. Process for the preparation of HMG-CoA reductase inhibitors intermediates
US4745229A (en) * 1986-02-28 1988-05-17 Kuraray Company Ltd. Process for preparing α, β-unsaturated aldehydes

Also Published As

Publication number Publication date
EP0306649B1 (de) 1992-03-04
HUT47237A (en) 1989-02-28
NO167795C (no) 1991-12-11
NO883071D0 (no) 1988-07-08
HU199768B (en) 1990-03-28
PT87928A (pt) 1989-06-30
FI883248A0 (fi) 1988-07-07
KR890001941A (ko) 1989-04-06
DE3722807A1 (de) 1989-01-19
GR3004588T3 (fi) 1993-04-28
ATE73123T1 (de) 1992-03-15
NZ225343A (en) 1991-02-26
ZA884920B (en) 1989-01-17
NO167795B (no) 1991-09-02
DK383988A (da) 1989-01-11
AU1888188A (en) 1989-01-12
PH27496A (en) 1993-07-23
DK383988D0 (da) 1988-07-08
ES2031959T3 (es) 1993-01-01
AU606712B2 (en) 1991-02-14
EP0306649A1 (de) 1989-03-15
PT87928B (pt) 1995-05-04
IL87035A0 (en) 1988-12-30
JPS6445337A (en) 1989-02-17
FI90412C (fi) 1994-02-10
NO883071L (no) 1989-01-11
DE3868794D1 (de) 1992-04-09
FI90412B (fi) 1993-10-29

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BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: HOECHST AKTIENGESELLSCHAFT