ZA879079B - Derivatives of bicyclic aminocarboxylic acids,a process and intermediates for their preparation,and their use - Google Patents

Derivatives of bicyclic aminocarboxylic acids,a process and intermediates for their preparation,and their use

Info

Publication number
ZA879079B
ZA879079B ZA879079A ZA879079A ZA879079B ZA 879079 B ZA879079 B ZA 879079B ZA 879079 A ZA879079 A ZA 879079A ZA 879079 A ZA879079 A ZA 879079A ZA 879079 B ZA879079 B ZA 879079B
Authority
ZA
South Africa
Prior art keywords
intermediates
derivatives
preparation
aminocarboxylic acids
bicyclic
Prior art date
Application number
ZA879079A
Other languages
English (en)
Inventor
Barton Derek
Potier Pierre
Herve Yolande
Thierry Josiane
Original Assignee
Hoechst Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Aktiengesellschaft filed Critical Hoechst Aktiengesellschaft
Publication of ZA879079B publication Critical patent/ZA879079B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
ZA879079A 1986-12-04 1987-12-03 Derivatives of bicyclic aminocarboxylic acids,a process and intermediates for their preparation,and their use ZA879079B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863641451 DE3641451A1 (de) 1986-12-04 1986-12-04 Derivate bicyclischer aminocarbonsaeuren, verfahren und zwischenprodukte zu deren herstellung sowie deren verwendung

Publications (1)

Publication Number Publication Date
ZA879079B true ZA879079B (en) 1988-06-01

Family

ID=6315467

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA879079A ZA879079B (en) 1986-12-04 1987-12-03 Derivatives of bicyclic aminocarboxylic acids,a process and intermediates for their preparation,and their use

Country Status (23)

Country Link
US (1) US4868307A (es)
EP (1) EP0270982B1 (es)
JP (2) JP2550369B2 (es)
KR (1) KR960000851B1 (es)
AR (1) AR243882A1 (es)
AT (1) ATE104295T1 (es)
AU (1) AU641498B2 (es)
CA (1) CA1317960C (es)
DE (2) DE3641451A1 (es)
DK (1) DK173877B1 (es)
EG (1) EG18416A (es)
ES (1) ES2053511T3 (es)
FI (1) FI90773C (es)
IE (1) IE63322B1 (es)
IL (1) IL84678A (es)
MA (1) MA21122A1 (es)
MX (1) MX172782B (es)
NO (1) NO170933C (es)
NZ (1) NZ222771A (es)
PH (1) PH26415A (es)
PT (1) PT86281B (es)
TN (1) TNSN87135A1 (es)
ZA (1) ZA879079B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3431541A1 (de) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
DE3639879A1 (de) * 1986-11-21 1988-06-01 Hoechst Ag Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
DE3731085A1 (de) * 1987-09-16 1989-04-06 Hoechst Ag Neue aminosaeureester, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
EP0331609A3 (de) * 1988-01-27 1992-07-01 Hoechst Aktiengesellschaft Angiotensin-Converting-Enzym-Hemmstoffe mit psychotroper Wirkung
HU904967D0 (en) * 1988-04-22 1991-01-28 Hoechst Ag Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
MXPA04005557A (es) * 2002-03-01 2005-05-17 Warner Lambert Co Metodo para tratar la osteoartritis.
EP1615885A1 (en) * 2003-04-15 2006-01-18 Warner-Lambert Company LLC B -fused bicyclic proline derivatives and their use for treating arthritic conditions
BRPI0409428A (pt) * 2003-04-15 2006-04-18 Warner Lambert Co derivados de prolina bicìclicos [c]-fundidos e a sua utilização para tratar estados artrìticos
EP1536017B1 (en) * 2003-10-30 2007-04-18 Sumitomo Chemical Company, Limited Process for producing optically active octahydro-1H-indole-2-carboxylic acid

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE52663B1 (en) * 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
ZA817261B (en) * 1980-10-23 1982-09-29 Schering Corp Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them
DE3174844D1 (en) * 1980-10-23 1986-07-24 Schering Corp Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
FR2510112A1 (fr) * 1981-07-24 1983-01-28 Roussel Uclaf Nouveaux derives du 2-oxo-pyrid-3-yl ou piperidin-3-yl indole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
CA1341296C (en) * 1981-12-29 2001-09-25 Hansjorg Urbach 2-azabicycloalkane-3-carboxylic acid derivatives, processes for their preparation, agents containing these compounds and their use
DE3246503A1 (de) * 1982-12-16 1984-06-20 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(5.3.0)-decan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung

Also Published As

Publication number Publication date
DK635887D0 (da) 1987-12-03
IL84678A0 (en) 1988-05-31
DK635887A (da) 1988-06-05
NZ222771A (en) 1991-01-29
EP0270982B1 (de) 1994-04-13
FI875319A (fi) 1988-06-05
PT86281B (pt) 1990-11-07
IE873288L (en) 1988-06-04
EG18416A (en) 1992-12-30
KR880007518A (ko) 1988-08-27
CA1317960C (en) 1993-05-18
DK173877B1 (da) 2002-01-21
NO170933C (no) 1992-12-30
NO875051L (no) 1988-06-06
AR243882A1 (es) 1993-09-30
AU609754B2 (en) 1991-05-09
ATE104295T1 (de) 1994-04-15
AU8209487A (en) 1988-06-09
MX172782B (es) 1994-01-13
JP2550369B2 (ja) 1996-11-06
JP2675992B2 (ja) 1997-11-12
EP0270982A3 (en) 1989-08-09
FI90773B (fi) 1993-12-15
PH26415A (en) 1992-07-15
JPS63145278A (ja) 1988-06-17
DE3641451A1 (de) 1988-06-16
AU7621091A (en) 1991-08-01
PT86281A (de) 1988-01-01
MA21122A1 (fr) 1988-07-01
NO170933B (no) 1992-09-21
TNSN87135A1 (fr) 1990-01-01
US4868307A (en) 1989-09-19
IL84678A (en) 1993-03-15
KR960000851B1 (ko) 1996-01-13
FI90773C (fi) 1994-03-25
MX9606A (es) 1993-07-01
EP0270982A2 (de) 1988-06-15
DE3789609D1 (de) 1994-05-19
FI875319A0 (fi) 1987-12-02
ES2053511T3 (es) 1994-08-01
NO875051D0 (no) 1987-12-03
JPH08283240A (ja) 1996-10-29
AU641498B2 (en) 1993-09-23
IE63322B1 (en) 1995-04-05

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