AU7621091A - Intermediates for derivatives of bicyclic aminocarboxylic acids, a process for their preparation, and their use - Google Patents

Intermediates for derivatives of bicyclic aminocarboxylic acids, a process for their preparation, and their use

Info

Publication number
AU7621091A
AU7621091A AU76210/91A AU7621091A AU7621091A AU 7621091 A AU7621091 A AU 7621091A AU 76210/91 A AU76210/91 A AU 76210/91A AU 7621091 A AU7621091 A AU 7621091A AU 7621091 A AU7621091 A AU 7621091A
Authority
AU
Australia
Prior art keywords
intermediates
derivatives
preparation
aminocarboxylic acids
bicyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU76210/91A
Other versions
AU641498B2 (en
Inventor
Derek Barton
Yolande Herve
Pierre Potier
Josiane Thierry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Sanofi Aventis Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland GmbH filed Critical Sanofi Aventis Deutschland GmbH
Publication of AU7621091A publication Critical patent/AU7621091A/en
Application granted granted Critical
Publication of AU641498B2 publication Critical patent/AU641498B2/en
Assigned to AVENTIS PHARMA DEUTSCHLAND GMBH reassignment AVENTIS PHARMA DEUTSCHLAND GMBH Alteration of Name(s) in Register under S187 Assignors: HOECHST AKTIENGESELLSCHAFT
Assigned to SANOFI-AVENTIS DEUTSCHLAND GMBH reassignment SANOFI-AVENTIS DEUTSCHLAND GMBH Request to Amend Deed and Register Assignors: AVENTIS PHARMA DEUTSCHLAND GMBH
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
AU76210/91A 1986-12-04 1991-04-29 Intermediates for derivatives of bicyclic aminocarboxylic acids, a process for their preparation, and their use Expired AU641498B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3641451 1986-12-04
DE19863641451 DE3641451A1 (en) 1986-12-04 1986-12-04 DERIVATIVES OF BICYCLIC AMINOCARBONIC ACIDS, METHODS AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU82094/87A Division AU609754C (en) 1986-12-04 1987-12-04 Derivatives of bicyclic aminocarboxylic acids, a process and intermediates for their preparation, and their use

Publications (2)

Publication Number Publication Date
AU7621091A true AU7621091A (en) 1991-08-01
AU641498B2 AU641498B2 (en) 1993-09-23

Family

ID=6315467

Family Applications (1)

Application Number Title Priority Date Filing Date
AU76210/91A Expired AU641498B2 (en) 1986-12-04 1991-04-29 Intermediates for derivatives of bicyclic aminocarboxylic acids, a process for their preparation, and their use

Country Status (23)

Country Link
US (1) US4868307A (en)
EP (1) EP0270982B1 (en)
JP (2) JP2550369B2 (en)
KR (1) KR960000851B1 (en)
AR (1) AR243882A1 (en)
AT (1) ATE104295T1 (en)
AU (1) AU641498B2 (en)
CA (1) CA1317960C (en)
DE (2) DE3641451A1 (en)
DK (1) DK173877B1 (en)
EG (1) EG18416A (en)
ES (1) ES2053511T3 (en)
FI (1) FI90773C (en)
IE (1) IE63322B1 (en)
IL (1) IL84678A (en)
MA (1) MA21122A1 (en)
MX (1) MX172782B (en)
NO (1) NO170933C (en)
NZ (1) NZ222771A (en)
PH (1) PH26415A (en)
PT (1) PT86281B (en)
TN (1) TNSN87135A1 (en)
ZA (1) ZA879079B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3333455A1 (en) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt METHOD FOR PRODUCING N-ALKYLATED DIPEPTIDES AND THEIR ESTERS
DE3413710A1 (en) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt METHOD FOR TREATING HEART INSUFFICIENCY
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3431541A1 (en) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt CIS, ENDO-2-AZABICYCLOALKAN-3-CARBONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND INTERMEDIATE PRODUCTS IN THEIR PRODUCTION
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
DE3639879A1 (en) * 1986-11-21 1988-06-01 Hoechst Ag METHOD FOR PRODUCING MONO, BI AND TRICYCLIC AMINO ACIDS, INTERMEDIATE PRODUCTS OF THIS METHOD, AND A METHOD FOR PRODUCING THE SAME
DE3731085A1 (en) * 1987-09-16 1989-04-06 Hoechst Ag NEW AMINO ACID ESTERS, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THEM AND THE USE THEREOF
EP0331609A3 (en) * 1988-01-27 1992-07-01 Hoechst Aktiengesellschaft Angiotensin converting enzyme inhibitors having psychotropic effects
HU904967D0 (en) * 1988-04-22 1991-01-28 Hoechst Ag Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
CA2477391A1 (en) * 2002-03-01 2003-09-12 Denis Schrier Method of treating osteoarthritis
EP1615885A1 (en) * 2003-04-15 2006-01-18 Warner-Lambert Company LLC B -fused bicyclic proline derivatives and their use for treating arthritic conditions
BRPI0409428A (en) * 2003-04-15 2006-04-18 Warner Lambert Co [c] fused bicyclic proline derivatives and their use to treat arthritic conditions
DE602004005947T2 (en) * 2003-10-30 2008-01-17 Sumitomo Chemical Co., Ltd. Process for the preparation of an optically active octahydro-1H-indole-2-carboxylic acid

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
IE52663B1 (en) * 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids
LU88621I2 (en) * 1980-10-23 1995-09-01 Schering Corp Sandopril
ZA817261B (en) * 1980-10-23 1982-09-29 Schering Corp Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them
FR2510112A1 (en) * 1981-07-24 1983-01-28 Roussel Uclaf NOVEL DERIVATIVES OF 2-OXO-PYRID-3-YL OR PIPERIDIN-3-YL INDOLE, THEIR SALTS, PREPARATION METHOD, MEDICAMENT APPLICATION AND COMPOSITIONS COMPRISING THE SAME
DE3226768A1 (en) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt DERIVATIVES OF CIS, ENDO-2-AZABICYCLO- (3.3.0) -OCTAN-3-CARBONIC ACID, METHOD FOR THE PRODUCTION THEREOF, THE MEANS CONTAINING THEM AND THE USE THEREOF
CA1341296C (en) * 1981-12-29 2001-09-25 Hansjorg Urbach 2-azabicycloalkane-3-carboxylic acid derivatives, processes for their preparation, agents containing these compounds and their use
DE3246503A1 (en) * 1982-12-16 1984-06-20 Hoechst Ag, 6230 Frankfurt DERIVATIVES OF CIS, ENDO-2-AZABICYCLO- (5.3.0) -DECAN-3-CARBONIC ACID, METHOD FOR THE PRODUCTION THEREOF, THESE AGENTS AND THE USE THEREOF

Also Published As

Publication number Publication date
NO170933B (en) 1992-09-21
JP2550369B2 (en) 1996-11-06
JP2675992B2 (en) 1997-11-12
FI90773C (en) 1994-03-25
DK173877B1 (en) 2002-01-21
KR880007518A (en) 1988-08-27
DK635887A (en) 1988-06-05
AU609754B2 (en) 1991-05-09
IL84678A0 (en) 1988-05-31
PT86281B (en) 1990-11-07
NO875051D0 (en) 1987-12-03
AR243882A1 (en) 1993-09-30
IE63322B1 (en) 1995-04-05
NZ222771A (en) 1991-01-29
EP0270982A2 (en) 1988-06-15
PT86281A (en) 1988-01-01
EG18416A (en) 1992-12-30
NO875051L (en) 1988-06-06
MA21122A1 (en) 1988-07-01
ZA879079B (en) 1988-06-01
IL84678A (en) 1993-03-15
DE3641451A1 (en) 1988-06-16
US4868307A (en) 1989-09-19
TNSN87135A1 (en) 1990-01-01
AU641498B2 (en) 1993-09-23
JPS63145278A (en) 1988-06-17
PH26415A (en) 1992-07-15
ATE104295T1 (en) 1994-04-15
CA1317960C (en) 1993-05-18
DE3789609D1 (en) 1994-05-19
NO170933C (en) 1992-12-30
DK635887D0 (en) 1987-12-03
FI875319A0 (en) 1987-12-02
IE873288L (en) 1988-06-04
FI875319A (en) 1988-06-05
FI90773B (en) 1993-12-15
AU8209487A (en) 1988-06-09
EP0270982B1 (en) 1994-04-13
ES2053511T3 (en) 1994-08-01
KR960000851B1 (en) 1996-01-13
EP0270982A3 (en) 1989-08-09
MX9606A (en) 1993-07-01
JPH08283240A (en) 1996-10-29
MX172782B (en) 1994-01-13

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Legal Events

Date Code Title Description
PC Assignment registered

Owner name: AVENTIS PHARMA DEUTSCHLAND GMBH

Free format text: FORMER OWNER WAS: HOECHST AKTIENGESELLSCHAFT