US5668255A
(en)
*
|
1984-06-07 |
1997-09-16 |
Seragen, Inc. |
Hybrid molecules having translocation region and cell-binding region
|
US6022950A
(en)
*
|
1984-06-07 |
2000-02-08 |
Seragen, Inc. |
Hybrid molecules having translocation region and cell-binding region
|
US5169939A
(en)
*
|
1985-05-21 |
1992-12-08 |
Massachusetts Institute Of Technology & Pres. & Fellows Of Harvard College |
Chimeric antibodies
|
US4892827A
(en)
*
|
1986-09-24 |
1990-01-09 |
The United States Of America As Represented By The Department Of Health And Human Services |
Recombinant pseudomonas exotoxins: construction of an active immunotoxin with low side effects
|
US6051405A
(en)
*
|
1986-09-24 |
2000-04-18 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Constructs encoding recombinant antibody-toxin fusion proteins
|
EP0422049A4
(en)
*
|
1988-05-09 |
1991-11-13 |
Us Health |
Vector for secretion of proteins directly into periplasm or culture medium
|
US5206353A
(en)
*
|
1988-07-23 |
1993-04-27 |
The United States Of America As Represented By The Department Of Health And Human Services |
CD-4/cytotoxic gene fusions
|
US5135736A
(en)
*
|
1988-08-15 |
1992-08-04 |
Neorx Corporation |
Covalently-linked complexes and methods for enhanced cytotoxicity and imaging
|
US5169933A
(en)
*
|
1988-08-15 |
1992-12-08 |
Neorx Corporation |
Covalently-linked complexes and methods for enhanced cytotoxicity and imaging
|
US5149782A
(en)
*
|
1988-08-19 |
1992-09-22 |
Tanox Biosystems, Inc. |
Molecular conjugates containing cell membrane-blending agents
|
ZA898139B
(en)
*
|
1988-11-17 |
1990-08-29 |
Hoffmann La Roche |
Recombinant interleukin-2 hybrid proteins
|
DK0383599T3
(da)
*
|
1989-02-17 |
1996-08-05 |
Merck & Co Inc |
Protein-anticancermiddel
|
US6406697B1
(en)
*
|
1989-02-23 |
2002-06-18 |
Genentech, Inc. |
Hybrid immunoglobulins
|
US5621078A
(en)
*
|
1989-03-22 |
1997-04-15 |
Merck & Co., Inc. |
Modified pseudomonas exotoxin PE40
|
IL93723A
(en)
*
|
1989-03-22 |
1997-02-18 |
Merck & Co Inc |
Cystein modified truncated pseudomonas exotoxin A
|
ES2091824T3
(es)
*
|
1989-04-21 |
1996-11-16 |
Us Health |
Proteina recombinante de fusion toxina anticuerpo.
|
US6207798B1
(en)
|
1989-08-03 |
2001-03-27 |
Merck & Co., Inc. |
Modified PE40 toxin fusion proteins
|
US5672683A
(en)
*
|
1989-09-07 |
1997-09-30 |
Alkermes, Inc. |
Transferrin neuropharmaceutical agent fusion protein
|
US5977307A
(en)
*
|
1989-09-07 |
1999-11-02 |
Alkermes, Inc. |
Transferrin receptor specific ligand-neuropharmaceutical agent fusion proteins
|
US6329508B1
(en)
|
1989-09-07 |
2001-12-11 |
Alkermes, Inc. |
Transferrin receptor reactive chimeric antibodies
|
US5527527A
(en)
*
|
1989-09-07 |
1996-06-18 |
Alkermes, Inc. |
Transferrin receptor specific antibody-neuropharmaceutical agent conjugates
|
WO1991009965A1
(en)
*
|
1989-12-21 |
1991-07-11 |
The United States Of America, Represented By The Secretary, United States Department Of Commerce |
An improved toxin for construction of immunotoxins
|
JP2610740B2
(ja)
*
|
1990-01-02 |
1997-05-14 |
アメリカ合衆国 |
標的特異的細胞障害性組み換えシュードモナスエキソトキシン
|
US5458878A
(en)
*
|
1990-01-02 |
1995-10-17 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
P. exotoxin fusio proteins have COOHG220101al alterations which increase cytotoxicity
|
US5110912A
(en)
*
|
1990-03-02 |
1992-05-05 |
Seragen, Inc. |
Purification of il-2-containing hybrid compounds
|
CA2082394C
(en)
*
|
1990-05-11 |
1999-07-20 |
Ira Pastan |
Pseudomonas exotoxins of low animal toxicity and high cytocidal activity
|
IL98528A0
(en)
*
|
1990-06-21 |
1992-07-15 |
Merck & Co Inc |
Pharmaceutical compositions containing hybrid for killing bladder cancer cells
|
US5241053A
(en)
*
|
1990-09-05 |
1993-08-31 |
Takeda Chemical Industries, Ltd. |
Fused proteins comprising glycoprotein gD of HSV-1 and LTB
|
US6099842A
(en)
*
|
1990-12-03 |
2000-08-08 |
The United States Of America As Represented By The Department Of Health And Human Services |
Recombinant immunotoxin composed of a single chain antibody reacting with the human transferrin receptor and diptheria toxin
|
US5571894A
(en)
*
|
1991-02-05 |
1996-11-05 |
Ciba-Geigy Corporation |
Recombinant antibodies specific for a growth factor receptor
|
ATE504650T1
(de)
*
|
1991-02-08 |
2011-04-15 |
Aventis Pharma Sa |
Nukleotidsequenzen, die für die veränderlichen bereiche der alpha-ketten menschlicher t-zell- rezeptoren kodieren sowie ihre verwendungen
|
FR2672616B1
(fr)
*
|
1991-02-08 |
1994-09-23 |
Roussel Uclaf |
Sequences nucleotidiques codant pour des regions variables de chaines alpha des recepteurs de lymphocytes t humains, segments peptidiques correspondants et les applications diagnostiques et therapeutiques.
|
JPH06502997A
(ja)
*
|
1991-02-12 |
1994-04-07 |
ルセル ユクラフ |
ヒトTリンパ球レセプターのβ鎖の可変領域をコードするヌクレオチド配列対応するペプチドセグメント並びに診断及び治療への利用
|
US5328984A
(en)
*
|
1991-03-04 |
1994-07-12 |
The United States As Represented By The Department Of Health & Human Services |
Recombinant chimeric proteins deliverable across cellular membranes into cytosol of target cells
|
US5223604A
(en)
*
|
1991-06-25 |
1993-06-29 |
S.P.I. Synthetic Peptides Incorporated |
Pseudomonas exoenzyme s peptide composition and method
|
US5939531A
(en)
*
|
1991-07-15 |
1999-08-17 |
Novartis Corp. |
Recombinant antibodies specific for a growth factor receptor
|
CA2081952A1
(en)
*
|
1991-11-08 |
1993-05-09 |
John J. Donnelly |
Recombinant dna sequences and plasmids for cellular immunity vaccines from bacterial toxin-antigen conjugates, and methods of their use
|
EP0646175B1
(en)
*
|
1992-06-18 |
2005-12-28 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
Recombinant pseudomonas exotoxin with increased activity
|
GB9326174D0
(en)
*
|
1993-12-22 |
1994-02-23 |
Biocine Sclavo |
Mucosal adjuvant
|
US6015555A
(en)
*
|
1995-05-19 |
2000-01-18 |
Alkermes, Inc. |
Transferrin receptor specific antibody-neuropharmaceutical or diagnostic agent conjugates
|
CA2234666A1
(en)
*
|
1995-10-13 |
1997-04-17 |
The Government Of The United States Of America, Represented By The Secre Tary, Department Of Health And Human Services |
Immunotoxin containing a disulfide-stabilized antibody fragment
|
RU2193413C2
(ru)
|
1996-03-01 |
2002-11-27 |
Новартис Аг |
Пептидные иммуногены для вакцинации и лечения аллергии
|
US6426075B1
(en)
|
1996-11-06 |
2002-07-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Protease-activatable pseudomonas exotoxin A-like proproteins
|
US6818222B1
(en)
|
1997-03-21 |
2004-11-16 |
Chiron Corporation |
Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
|
US20030198772A1
(en)
*
|
1997-06-26 |
2003-10-23 |
Weder Donald E. |
Polymeric materials having a texture or appearance simulating the texture or appearance of paper
|
US20020004113A1
(en)
*
|
1997-06-26 |
2002-01-10 |
Weder Donald E. |
Decorative cover for flower pot or floral grouping formed of polymeric materials having a texture or appearance simulating the texture or appearance of paper
|
US7314632B1
(en)
*
|
1997-07-11 |
2008-01-01 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Pseudomonas exotoxin A-like chimeric immunogens
|
US20030054012A1
(en)
*
|
2000-05-12 |
2003-03-20 |
Fitzgerald David J. |
Pseudomonas exotoxin a-like chimeric immunogens for eliciting a secretory iga-mediated immune response
|
DK1000163T3
(da)
*
|
1997-07-11 |
2006-02-06 |
Us Gov Health & Human Serv |
Pseudomonas-exotoksin A-lignende kimære immunogener
|
US6077676A
(en)
*
|
1997-12-18 |
2000-06-20 |
Spectral Diagnostics, Inc. |
Single-chain polypeptides comprising troponin I and troponin C
|
US6794128B2
(en)
|
1998-04-24 |
2004-09-21 |
The Regents Of The University Of California |
Methods of selecting internalizing antibodies
|
AU2004201055B2
(en)
*
|
1998-04-24 |
2007-08-23 |
The Regents Of The University Of California |
Internalizing ErbB2 antibodies
|
US7244826B1
(en)
*
|
1998-04-24 |
2007-07-17 |
The Regents Of The University Of California |
Internalizing ERB2 antibodies
|
US20020142000A1
(en)
*
|
1999-01-15 |
2002-10-03 |
Digan Mary Ellen |
Anti-CD3 immunotoxins and therapeutic uses therefor
|
US20030143233A1
(en)
*
|
1999-06-07 |
2003-07-31 |
Neorx Corporation |
Streptavidin expressed gene fusions and methods of use thereof
|
US20030103948A1
(en)
*
|
1999-06-07 |
2003-06-05 |
Neorx Corporation |
Streptavidin expressed gene fusions and methods of use thereof
|
US7144991B2
(en)
|
1999-06-07 |
2006-12-05 |
Aletheon Pharmaceuticals, Inc. |
Streptavidin expressed gene fusions and methods of use thereof
|
US6838553B1
(en)
*
|
1999-10-05 |
2005-01-04 |
Academia Sinica |
Peptide repeat immunogens
|
US7078486B2
(en)
*
|
1999-12-10 |
2006-07-18 |
Spectral Diagnostics, Inc. |
Single-chain polypeptides comprising troponin I and troponin C
|
EP1278830A4
(en)
*
|
2000-04-25 |
2004-05-12 |
Univ Oklahoma |
IDENTIFICATION AND APPLICATIONS OF A HYALURONAN RECEPTOR
|
US20050287638A1
(en)
*
|
2000-04-25 |
2005-12-29 |
Weigel Paul H |
Hyaluronan receptor for endocytosis, variants thereof, and methods of making and using same
|
DE60137969D1
(de)
*
|
2000-12-21 |
2009-04-23 |
Us Gov Health & Human Serv |
Ein chimäres protein das nichttoxische pseudomonas exotoxin a und typ iv pilin sequenzen enthält
|
WO2002086093A2
(en)
*
|
2001-04-25 |
2002-10-31 |
Weigel Paul H |
Methods of using a hyaluronan receptor
|
ES2342929T3
(es)
|
2001-09-26 |
2010-07-19 |
The Government of the United States of America as represented by the Secretary of Health and Human |
Anticuerpos anti-cd22 con afinidad aumentada por las celulas leucemicas que expresan cd22.
|
EP1448237A1
(en)
*
|
2001-11-09 |
2004-08-25 |
Neopharm, Inc. |
Selective treatment of il-13 expressing tumors
|
WO2004087758A2
(en)
*
|
2003-03-26 |
2004-10-14 |
Neopharm, Inc. |
Il 13 receptor alpha 2 antibody and methods of use
|
EP2829283B1
(en)
|
2003-04-30 |
2017-06-07 |
Universität Zürich |
Methods for treating cancer using an immunotoxin
|
JP4813364B2
(ja)
|
2003-11-25 |
2011-11-09 |
アメリカ合衆国 |
突然変異型抗cd22抗体および免疫複合体
|
US7999077B2
(en)
*
|
2004-09-30 |
2011-08-16 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
IRTA2 antibodies and methods of use
|
EP1804832A4
(en)
*
|
2004-10-04 |
2008-12-24 |
Trinity Biosystems Inc |
METHOD AND COMPOSITIONS FOR THE NADLESS DELIVERY OF MACROMOLECULES
|
US7611714B2
(en)
|
2004-10-04 |
2009-11-03 |
Trinity Biosystems, Inc. |
Methods and compositions for immunizing against Pseudomonas infection
|
CA2591992A1
(en)
|
2004-12-22 |
2006-06-29 |
The Salk Institute For Biological Studies |
Compositions and methods for producing recombinant proteins
|
WO2006125076A2
(en)
|
2005-05-18 |
2006-11-23 |
Trinity Biosystems, Inc. |
Methods and compositions for immunizing against chlamydia infection
|
CA2941466C
(en)
*
|
2005-07-29 |
2019-12-03 |
The Government Of The United States Of America, As Represented By The Secretary Of Health And Human Services |
Mutated pseudomonas exotoxins with reduced antigenicity
|
WO2007067597A2
(en)
*
|
2005-12-05 |
2007-06-14 |
Trinity Biosystems, Inc. |
Methods and compositions for needleless delivery of binding partners
|
CA2631952A1
(en)
*
|
2005-12-05 |
2007-06-14 |
Trinity Biosystems, Inc. |
Methods and compositions for needleless delivery of antibodies
|
EP2010205A2
(en)
|
2006-03-16 |
2009-01-07 |
Trinity Biosystems, Inc. |
Methods for increasing the size of animals using needleless delivery constructs
|
EP1878744A1
(en)
*
|
2006-07-13 |
2008-01-16 |
Max-Delbrück-Centrum für Molekulare Medizin (MDC) |
Epitope-tag for surface-expressed T-cell receptor proteins, uses thereof and method of selecting host cells expressing them
|
US20090092660A1
(en)
*
|
2006-08-09 |
2009-04-09 |
Trinity Biosystems, Inc. |
Methods and compositions for needleless delivery of particles
|
EP2178559B1
(en)
*
|
2007-07-20 |
2015-06-24 |
The General Hospital Corporation |
Recombinant vibrio cholerae exotoxins
|
WO2009032954A1
(en)
|
2007-09-04 |
2009-03-12 |
The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
Deletions in domain ii of pseudomonas exotoxin a that reduce non-specific toxicity
|
AU2008302111B2
(en)
*
|
2007-09-21 |
2014-04-24 |
The Regents Of The University Of California |
Targeted interferon demonstrates potent apoptotic and anti-tumor activities
|
WO2010045495A2
(en)
|
2008-10-16 |
2010-04-22 |
University Of Pittsburgh-Of The Commonwealth System Of Higher Education |
Fully human antibodies to high molecular weight-melanoma associated antigen and uses thereof
|
WO2011031441A1
(en)
|
2009-08-28 |
2011-03-17 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Therapy with a chimeric molecule and a pro-apoptotic agent
|
CN102655882B
(zh)
|
2009-09-11 |
2014-11-19 |
美国政府健康及人类服务部 |
具有降低的免疫原性的改进的假单胞菌外毒素a
|
WO2011100455A1
(en)
|
2010-02-12 |
2011-08-18 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Inhibition of antibody responses to foreign proteins
|
JP5839411B2
(ja)
|
2010-03-30 |
2016-01-06 |
フェニックス インク. |
組み換え型毒素タンパク質の高レベルの発現
|
EP3135692B8
(en)
|
2010-06-16 |
2019-03-20 |
University of Pittsburgh - Of the Commonwealth System of Higher Education |
Antibodies to endoplasmin and their use
|
PL3434346T3
(pl)
|
2010-07-30 |
2021-04-06 |
Medimmune, Llc |
Oczyszczone aktywne polipeptydy lub immunokoniugaty
|
US11246915B2
(en)
|
2010-09-15 |
2022-02-15 |
Applied Molecular Transport Inc. |
Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo
|
TW201305200A
(zh)
*
|
2010-11-30 |
2013-02-01 |
Genentech Inc |
低親和力血腦障壁受體抗體及其用途
|
EP2699603B1
(en)
|
2011-04-19 |
2016-03-02 |
The United States of America As Represented by the Secretary Department of Health and Human Services |
Human monoclonal antibodies specific for glypican-3 and use thereof
|
AU2012268013B2
(en)
|
2011-06-09 |
2016-11-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Pseudomonas exotoxin A with less immunogenic T cell and/or B cell epitopes
|
US8932586B2
(en)
|
2011-09-06 |
2015-01-13 |
Intrexon Corporation |
Modified forms of Pseudomonas exotoxin A
|
WO2013039916A1
(en)
|
2011-09-12 |
2013-03-21 |
The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services |
Compositions for and methods of treatment and enhanced detection of non-pituitary tumors
|
WO2013040141A1
(en)
|
2011-09-16 |
2013-03-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Pseudomonas exotoxin a with less immunogenic b cell epitopes
|
EP2764025B1
(en)
|
2011-10-04 |
2017-11-29 |
IGEM Therapeutics Limited |
Ige-antibodies against hmw-maa
|
US9169304B2
(en)
|
2012-05-01 |
2015-10-27 |
Pfenex Inc. |
Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
|
SG11201407972RA
(en)
|
2012-06-01 |
2015-01-29 |
Us Health |
High-affinity monoclonal antibodies to glypican-3 and use thereof
|
WO2014031476A1
(en)
|
2012-08-21 |
2014-02-27 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Mesothelin domain-specific monoclonal antibodies and use thereof
|
US9416190B2
(en)
|
2012-09-27 |
2016-08-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Mesothelin antibodies and methods for eliciting potent antitumor activity
|
WO2014089354A1
(en)
|
2012-12-07 |
2014-06-12 |
The Regents Of The University Of California |
Cd138-targeted interferon demonstrates potent apoptotic and anti-tumor activities
|
US9764006B2
(en)
|
2012-12-10 |
2017-09-19 |
The General Hospital Corporation |
Bivalent IL-2 fusion toxins
|
WO2014100443A2
(en)
|
2012-12-20 |
2014-06-26 |
Medimmune, Llc |
Methods of producing immunoconjugates
|
US9790282B2
(en)
|
2013-03-25 |
2017-10-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-CD276 polypeptides, proteins, and chimeric antigen receptors
|
WO2014194100A1
(en)
|
2013-05-29 |
2014-12-04 |
The Regents Of The University Of California |
Anti-cspg4 fusions with interferon for the treatment of malignancy
|
CA2926215A1
(en)
|
2013-10-06 |
2015-04-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Modified pseudomonas exotoxin a
|
ES2764833T3
(es)
|
2013-10-11 |
2020-06-04 |
The United States Of America Represented By The Sec Dep Of Health And Human Services |
Anticuerpos contra TEM8 y su uso
|
US20160280798A1
(en)
|
2013-11-06 |
2016-09-29 |
The United States Of America, As Represented By The Secretary Department Of Health & Human Service |
Alk antibodies, conjugates, and chimeric antigen receptors, and their use
|
US10246505B2
(en)
|
2013-11-25 |
2019-04-02 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptors to control HIV infection
|
WO2015120058A2
(en)
|
2014-02-05 |
2015-08-13 |
Molecular Templates, Inc. |
Methods of screening, selecting, and identifying cytotoxic recombinant polypeptides based on an interim diminution of ribotoxicity
|
AU2015255834B2
(en)
|
2014-05-07 |
2020-05-21 |
Applied Molecular Transport Llc |
Cholix toxin-derived fusion molecules for oral delivery of biologically active cargo
|
CN106999578B
(zh)
|
2014-07-31 |
2022-03-04 |
美国政府(由卫生和人类服务部的部长所代表) |
针对epha4的人类单克隆抗体和其用途
|
JP6613304B2
(ja)
|
2014-09-17 |
2019-12-04 |
ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
抗cd276抗体(b7h3)
|
WO2016146833A1
(en)
|
2015-03-19 |
2016-09-22 |
F. Hoffmann-La Roche Ag |
Biomarkers for nad(+)-diphthamide adp ribosyltransferase resistance
|
CA2981509A1
(en)
|
2015-03-30 |
2016-10-06 |
The Board Of Regents Of The Nevada System Of Higher Educ. On Behalf Of The University Of Nevada, La |
Compositions comprising talens and methods of treating hiv
|
CN108139375A
(zh)
|
2015-06-26 |
2018-06-08 |
贝斯以色列女执事医疗中心股份有限公司 |
靶向髓样衍生的抑制细胞中的四跨膜蛋白33(tspan33)的癌症疗法
|
CN108367062B
(zh)
|
2015-10-13 |
2022-05-06 |
赛诺菲巴斯德有限公司 |
抗金黄色葡萄球菌的免疫原性组合物
|
EP3184547A1
(en)
|
2015-10-29 |
2017-06-28 |
F. Hoffmann-La Roche AG |
Anti-tpbg antibodies and methods of use
|
EP3374396A1
(en)
|
2015-11-13 |
2018-09-19 |
The United States of America, as represented by the secretary, Department of Health and Human Services |
Anti-bcma polypeptides and proteins
|
WO2017196847A1
(en)
|
2016-05-10 |
2017-11-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Variable new antigen receptor (vnar) antibodies and antibody conjugates targeting tumor and viral antigens
|
WO2017214182A1
(en)
|
2016-06-07 |
2017-12-14 |
The United States Of America. As Represented By The Secretary, Department Of Health & Human Services |
Fully human antibody targeting pdi for cancer immunotherapy
|
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(en)
|
2016-08-02 |
2018-02-08 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
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|
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(en)
|
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2018-06-28 |
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Human monoclonal antibodies specific for flt3 and uses thereof
|
US11390683B2
(en)
|
2017-05-18 |
2022-07-19 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-mesothelin polypeptides and proteins
|
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(en)
|
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2018-11-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
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|
WO2019006280A1
(en)
|
2017-06-30 |
2019-01-03 |
Lentigen Technology, Inc. |
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|
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(en)
|
2017-06-30 |
2019-01-03 |
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|
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(en)
|
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|
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(en)
|
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2023-10-24 |
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|
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(en)
|
2017-10-06 |
2021-12-14 |
University Of Utah Research Foundation |
Immune tolerant elastin-like peptide tetramer guided nanoparticles and methods of use
|
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(zh)
|
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2020-12-18 |
应用分子运输公司 |
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|
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(en)
|
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2021-01-28 |
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|
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(en)
|
2018-08-08 |
2020-02-13 |
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|
KR102353086B1
(ko)
*
|
2018-09-07 |
2022-01-20 |
아주대학교산학협력단 |
신규 면역독소 제조방법
|
ES2911075T3
(es)
|
2018-11-07 |
2022-05-17 |
Applied Molecular Transport Inc |
Constructos de administración para transcitosis y métodos relacionados
|
SG11202104734YA
(en)
|
2018-11-07 |
2021-06-29 |
Applied Molecular Transport Inc |
Cholix-derived carriers for oral delivery of heterologous payload
|
US20220064324A1
(en)
|
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2022-03-03 |
The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
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|
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(zh)
|
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2021-12-10 |
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|
US20220127368A1
(en)
|
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|
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(en)
|
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|
BR112022002962A2
(pt)
|
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2022-07-05 |
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Composições, formulações e produção e purificação de interleucina
|
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(zh)
|
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美国政府(由卫生和人类服务部的部长所代表) |
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|
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|
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|
WO2021173674A1
(en)
|
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2021-09-02 |
A2 Biotherapeutics, Inc. |
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|
US20230391852A1
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|
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The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
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|
US20240075158A1
(en)
|
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|
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(en)
|
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|
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(zh)
|
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|
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|
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|
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|
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|
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|
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|
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|
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|