ATE504650T1 - Nukleotidsequenzen, die für die veränderlichen bereiche der alpha-ketten menschlicher t-zell- rezeptoren kodieren sowie ihre verwendungen - Google Patents

Nukleotidsequenzen, die für die veränderlichen bereiche der alpha-ketten menschlicher t-zell- rezeptoren kodieren sowie ihre verwendungen

Info

Publication number
ATE504650T1
ATE504650T1 AT06009929T AT06009929T ATE504650T1 AT E504650 T1 ATE504650 T1 AT E504650T1 AT 06009929 T AT06009929 T AT 06009929T AT 06009929 T AT06009929 T AT 06009929T AT E504650 T1 ATE504650 T1 AT E504650T1
Authority
AT
Austria
Prior art keywords
sequences
human
nucleotide sequences
sequences encoding
cell receptors
Prior art date
Application number
AT06009929T
Other languages
English (en)
Inventor
Thierry Hercend
Frederic Triebel
Sergio Roman-Ronan
Laurent Ferradini
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9101487A external-priority patent/FR2672616B1/fr
Priority claimed from FR9104527A external-priority patent/FR2675156B1/fr
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of ATE504650T1 publication Critical patent/ATE504650T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
AT06009929T 1991-02-08 1992-02-07 Nukleotidsequenzen, die für die veränderlichen bereiche der alpha-ketten menschlicher t-zell- rezeptoren kodieren sowie ihre verwendungen ATE504650T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9101487A FR2672616B1 (fr) 1991-02-08 1991-02-08 Sequences nucleotidiques codant pour des regions variables de chaines alpha des recepteurs de lymphocytes t humains, segments peptidiques correspondants et les applications diagnostiques et therapeutiques.
FR9104527A FR2675156B1 (fr) 1991-04-12 1991-04-12 Sequences nucleotidiques codant pour des regions variables de chaines alpha des recepteurs des lymphocytes t humains, segments peptidiques correspondants et les applications diagnostiques et therapeutiques.

Publications (1)

Publication Number Publication Date
ATE504650T1 true ATE504650T1 (de) 2011-04-15

Family

ID=26228502

Family Applications (2)

Application Number Title Priority Date Filing Date
AT92905817T ATE338134T1 (de) 1991-02-08 1992-02-07 Nukleotidsequenzen, die für die veränderlichen bereiche der alpha-ketten menschlicher t-zell- rezeptoren kodieren sowie ihre verwendungen
AT06009929T ATE504650T1 (de) 1991-02-08 1992-02-07 Nukleotidsequenzen, die für die veränderlichen bereiche der alpha-ketten menschlicher t-zell- rezeptoren kodieren sowie ihre verwendungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT92905817T ATE338134T1 (de) 1991-02-08 1992-02-07 Nukleotidsequenzen, die für die veränderlichen bereiche der alpha-ketten menschlicher t-zell- rezeptoren kodieren sowie ihre verwendungen

Country Status (12)

Country Link
US (3) US5817511A (de)
EP (2) EP1721978B1 (de)
JP (1) JPH05509234A (de)
KR (1) KR100242278B1 (de)
AT (2) ATE338134T1 (de)
AU (1) AU660660B2 (de)
CA (1) CA2079879C (de)
DE (2) DE69233652T2 (de)
DK (1) DK0529033T3 (de)
ES (1) ES2271940T3 (de)
IE (1) IE920413A1 (de)
WO (1) WO1992013949A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2072356A1 (en) * 1989-12-29 1991-06-30 James L. Urban Diagnosis and treatment of diseases
US7294712B2 (en) * 1990-06-04 2007-11-13 Aventis Pharma S.A. Nucleotide sequences coding for variable regions of β chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses
ATE338134T1 (de) * 1991-02-08 2006-09-15 Aventis Pharma Sa Nukleotidsequenzen, die für die veränderlichen bereiche der alpha-ketten menschlicher t-zell- rezeptoren kodieren sowie ihre verwendungen
AU660306B2 (en) * 1991-02-12 1995-06-22 Roussel-Uclaf Nucleotidic sequences coding for variable regions of beta chains of human T lymphocyte receptors, corresponding peptidic segments and diagnostic and therapeutic applications
DE4225569C2 (de) * 1992-08-03 1996-04-25 Max Planck Gesellschaft Verwendung einer Sonde zur Tumordiagnostik oder Tumortherapie
JP3875730B2 (ja) * 1993-02-22 2007-01-31 サノフィ・アベンティス株式会社 自己免疫疾患の予防治療剤
CA2188182A1 (en) * 1994-04-18 1995-10-26 Steven M. Friedman Conserved t-cell receptor sequences
EP1095948A1 (de) * 1999-10-28 2001-05-02 Universitätsklinikum Freiburg Idiotype Impstoffe
KR100363271B1 (ko) * 2000-06-12 2002-12-05 주식회사 동진쎄미켐 포토레지스트 리무버 조성물
US20060275747A1 (en) * 2001-12-07 2006-12-07 Hardy Stephen F Endogenous retrovirus up-regulated in prostate cancer
EP2302039A1 (de) 2002-06-13 2011-03-30 Novartis Vaccines and Diagnostics, Inc. Virusähnliche Partikel mit HML-2 gag Polypeptid
WO2004005465A2 (en) * 2002-07-03 2004-01-15 Institute For Scientific Research, Inc. Compositions and methods for the detection of human t cell receptor variable family gene expression
FR2863274B1 (fr) 2003-12-05 2012-11-16 Commissariat Energie Atomique Procede d'evaluation quantitative d'un rearrangement ou d'une recombinaison genetique ciblee d'un individu et ses applications.
EP2044949A1 (de) 2007-10-05 2009-04-08 Immutep Verwendung von rekombinantem LAG-3 oder Derivaten daraus zur Auslösung einer Monozyten-Immunreaktion
US8497071B2 (en) * 2009-06-29 2013-07-30 California Institute Of Technology Isolation of unknown rearranged T-cell receptors from single cells
GB201322626D0 (en) 2013-12-19 2014-02-05 Immutep S A Combined preparations for the treatment of cancer
JOP20200094A1 (ar) 2014-01-24 2017-06-16 Dana Farber Cancer Inst Inc جزيئات جسم مضاد لـ pd-1 واستخداماتها
CN106103484B (zh) 2014-03-14 2021-08-20 诺华股份有限公司 针对lag-3的抗体分子及其用途
US10202640B2 (en) * 2014-05-07 2019-02-12 The Board Of Trustees Of The Leland Stanford Junior University Single cell analysis of T cells using high-throughput multiplex amplification and deep sequencing
GB201500374D0 (en) 2015-01-09 2015-02-25 Immutep S A Combined preparations for the treatment of cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874845A (en) * 1984-06-13 1989-10-17 Massachusetts Institute Of Technology T lymphocyte receptor subunit
EP0200350A3 (de) * 1985-04-15 1987-05-13 The Ontario Cancer Institute Nukleinsäure mit Code für ein T-Zellen-Antigenrezeptor-Polypeptid
KR960001741B1 (ko) * 1985-12-03 1996-02-05 티 셀 사이언시즈, 인코포레이티드 세포-없는 t 세포항원 수용체 단백질의 감지방법
US4892827A (en) * 1986-09-24 1990-01-09 The United States Of America As Represented By The Department Of Health And Human Services Recombinant pseudomonas exotoxins: construction of an active immunotoxin with low side effects
US5223426A (en) * 1988-12-15 1993-06-29 T Cell Sciences, Inc. Monoclonal antibodies reactive with defined regions of the t-cell antigen receptor
US5216132A (en) * 1990-01-12 1993-06-01 Protein Design Labs, Inc. Soluble t-cell antigen receptor chimeric antigens
ATE338134T1 (de) * 1991-02-08 2006-09-15 Aventis Pharma Sa Nukleotidsequenzen, die für die veränderlichen bereiche der alpha-ketten menschlicher t-zell- rezeptoren kodieren sowie ihre verwendungen

Also Published As

Publication number Publication date
IE920413A1 (en) 1992-08-12
CA2079879C (fr) 2007-11-06
ATE338134T1 (de) 2006-09-15
CA2079879A1 (fr) 1992-08-09
US5817511A (en) 1998-10-06
JPH05509234A (ja) 1993-12-22
US5798231A (en) 1998-08-25
AU660660B2 (en) 1995-07-06
WO1992013949A1 (fr) 1992-08-20
AU1360392A (en) 1992-09-07
KR100242278B1 (ko) 2000-02-01
DE69233804D1 (de) 2011-05-19
DE69233652D1 (de) 2006-10-12
DE69233652T2 (de) 2007-09-27
DK0529033T3 (da) 2007-01-08
US6114516A (en) 2000-09-05
EP1721978A1 (de) 2006-11-15
EP0529033B1 (de) 2006-08-30
ES2271940T3 (es) 2007-04-16
EP0529033A1 (de) 1993-03-03
EP1721978B1 (de) 2011-04-06

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