DE69233652D1 - Nukleotidsequenzen, die für die veränderlichen bereiche der alpha-ketten menschlicher t-zell-rezeptoren kodieren sowie ihre verwendungen - Google Patents
Nukleotidsequenzen, die für die veränderlichen bereiche der alpha-ketten menschlicher t-zell-rezeptoren kodieren sowie ihre verwendungenInfo
- Publication number
- DE69233652D1 DE69233652D1 DE69233652T DE69233652T DE69233652D1 DE 69233652 D1 DE69233652 D1 DE 69233652D1 DE 69233652 T DE69233652 T DE 69233652T DE 69233652 T DE69233652 T DE 69233652T DE 69233652 D1 DE69233652 D1 DE 69233652D1
- Authority
- DE
- Germany
- Prior art keywords
- sequences
- human
- nucleotide sequences
- cell receptors
- alpha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9101487A FR2672616B1 (fr) | 1991-02-08 | 1991-02-08 | Sequences nucleotidiques codant pour des regions variables de chaines alpha des recepteurs de lymphocytes t humains, segments peptidiques correspondants et les applications diagnostiques et therapeutiques. |
FR9101487 | 1991-02-08 | ||
FR9104527 | 1991-04-12 | ||
FR9104527A FR2675156B1 (fr) | 1991-04-12 | 1991-04-12 | Sequences nucleotidiques codant pour des regions variables de chaines alpha des recepteurs des lymphocytes t humains, segments peptidiques correspondants et les applications diagnostiques et therapeutiques. |
PCT/FR1992/000111 WO1992013949A1 (fr) | 1991-02-08 | 1992-02-07 | Sequences nucleotidiques codant pour des regions variables de chaines alpha des recepteurs des lymphocytes humains ainsi que leurs applications |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69233652D1 true DE69233652D1 (de) | 2006-10-12 |
DE69233652T2 DE69233652T2 (de) | 2007-09-27 |
Family
ID=26228502
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69233804T Expired - Lifetime DE69233804D1 (de) | 1991-02-08 | 1992-02-07 | Nukleotidsequenzen, die für die veränderlichen Bereiche der Alpha-Ketten menschlicher T-Zell-Rezeptoren kodieren sowie ihre Verwendungen |
DE69233652T Expired - Lifetime DE69233652T2 (de) | 1991-02-08 | 1992-02-07 | Nukleotidsequenzen, die für die veränderlichen bereiche der alpha-ketten menschlicher t-zell-rezeptoren kodieren sowie ihre verwendungen |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69233804T Expired - Lifetime DE69233804D1 (de) | 1991-02-08 | 1992-02-07 | Nukleotidsequenzen, die für die veränderlichen Bereiche der Alpha-Ketten menschlicher T-Zell-Rezeptoren kodieren sowie ihre Verwendungen |
Country Status (12)
Country | Link |
---|---|
US (3) | US5817511A (de) |
EP (2) | EP1721978B1 (de) |
JP (1) | JPH05509234A (de) |
KR (1) | KR100242278B1 (de) |
AT (2) | ATE504650T1 (de) |
AU (1) | AU660660B2 (de) |
CA (1) | CA2079879C (de) |
DE (2) | DE69233804D1 (de) |
DK (1) | DK0529033T3 (de) |
ES (1) | ES2271940T3 (de) |
IE (1) | IE920413A1 (de) |
WO (1) | WO1992013949A1 (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2072356A1 (en) * | 1989-12-29 | 1991-06-30 | James L. Urban | Diagnosis and treatment of diseases |
US7294712B2 (en) * | 1990-06-04 | 2007-11-13 | Aventis Pharma S.A. | Nucleotide sequences coding for variable regions of β chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses |
JPH05509234A (ja) * | 1991-02-08 | 1993-12-22 | ルセル ユクラフ | ヒトTリンパ球レセプターのα鎖の可変領域をコードするヌクレオチド配列対応するペプチドセグメント並びに診断及び治療への利用 |
IE920447A1 (en) * | 1991-02-12 | 1992-08-12 | Roussel Uclaf | NUCLEOTIDE SEQUENCES CODING FOR ß-CHAIN VARIABLE REGIONS OF¹HUMAN T-LYMPHOCYTE RECEPTORS, CORRESPONDING PEPTIDE SEGMENTS¹AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS |
DE4225569C2 (de) * | 1992-08-03 | 1996-04-25 | Max Planck Gesellschaft | Verwendung einer Sonde zur Tumordiagnostik oder Tumortherapie |
JP3875730B2 (ja) * | 1993-02-22 | 2007-01-31 | サノフィ・アベンティス株式会社 | 自己免疫疾患の予防治療剤 |
CA2188182A1 (en) * | 1994-04-18 | 1995-10-26 | Steven M. Friedman | Conserved t-cell receptor sequences |
EP1095948A1 (de) * | 1999-10-28 | 2001-05-02 | Universitätsklinikum Freiburg | Idiotype Impstoffe |
KR100363271B1 (ko) * | 2000-06-12 | 2002-12-05 | 주식회사 동진쎄미켐 | 포토레지스트 리무버 조성물 |
US20060275747A1 (en) * | 2001-12-07 | 2006-12-07 | Hardy Stephen F | Endogenous retrovirus up-regulated in prostate cancer |
JP2005535308A (ja) | 2002-06-13 | 2005-11-24 | カイロン コーポレイション | Hml−2ポリペプチド発現用ベクター |
EP1517995A4 (de) * | 2002-07-03 | 2007-07-11 | Inst Scient Res Inc | Zusammensetzungen und verfahren zum nachweis der expression von genen der variablen menschlichen t-zellrezeptor-familie |
FR2863274B1 (fr) | 2003-12-05 | 2012-11-16 | Commissariat Energie Atomique | Procede d'evaluation quantitative d'un rearrangement ou d'une recombinaison genetique ciblee d'un individu et ses applications. |
EP2044949A1 (de) | 2007-10-05 | 2009-04-08 | Immutep | Verwendung von rekombinantem LAG-3 oder Derivaten daraus zur Auslösung einer Monozyten-Immunreaktion |
US8497071B2 (en) * | 2009-06-29 | 2013-07-30 | California Institute Of Technology | Isolation of unknown rearranged T-cell receptors from single cells |
GB201322626D0 (en) | 2013-12-19 | 2014-02-05 | Immutep S A | Combined preparations for the treatment of cancer |
JOP20200094A1 (ar) | 2014-01-24 | 2017-06-16 | Dana Farber Cancer Inst Inc | جزيئات جسم مضاد لـ pd-1 واستخداماتها |
CU24481B1 (es) | 2014-03-14 | 2020-03-04 | Immutep Sas | Moléculas de anticuerpo que se unen a lag-3 |
US10202640B2 (en) * | 2014-05-07 | 2019-02-12 | The Board Of Trustees Of The Leland Stanford Junior University | Single cell analysis of T cells using high-throughput multiplex amplification and deep sequencing |
GB201500374D0 (en) | 2015-01-09 | 2015-02-25 | Immutep S A | Combined preparations for the treatment of cancer |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4874845A (en) * | 1984-06-13 | 1989-10-17 | Massachusetts Institute Of Technology | T lymphocyte receptor subunit |
EP0200350A3 (de) * | 1985-04-15 | 1987-05-13 | The Ontario Cancer Institute | Nukleinsäure mit Code für ein T-Zellen-Antigenrezeptor-Polypeptid |
EP0616811A1 (de) * | 1985-12-03 | 1994-09-28 | T Cell Sciences, Inc. | Zellfreier T-Zell-Antigenrezeptor und dessen klinische Verwendungen |
US4892827A (en) * | 1986-09-24 | 1990-01-09 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant pseudomonas exotoxins: construction of an active immunotoxin with low side effects |
US5223426A (en) * | 1988-12-15 | 1993-06-29 | T Cell Sciences, Inc. | Monoclonal antibodies reactive with defined regions of the t-cell antigen receptor |
US5216132A (en) * | 1990-01-12 | 1993-06-01 | Protein Design Labs, Inc. | Soluble t-cell antigen receptor chimeric antigens |
JPH05509234A (ja) * | 1991-02-08 | 1993-12-22 | ルセル ユクラフ | ヒトTリンパ球レセプターのα鎖の可変領域をコードするヌクレオチド配列対応するペプチドセグメント並びに診断及び治療への利用 |
-
1992
- 1992-02-07 JP JP4505541A patent/JPH05509234A/ja active Pending
- 1992-02-07 AU AU13603/92A patent/AU660660B2/en not_active Expired
- 1992-02-07 KR KR1019920702482A patent/KR100242278B1/ko not_active IP Right Cessation
- 1992-02-07 CA CA002079879A patent/CA2079879C/fr not_active Expired - Lifetime
- 1992-02-07 IE IE041392A patent/IE920413A1/en unknown
- 1992-02-07 DE DE69233804T patent/DE69233804D1/de not_active Expired - Lifetime
- 1992-02-07 DE DE69233652T patent/DE69233652T2/de not_active Expired - Lifetime
- 1992-02-07 DK DK92905817T patent/DK0529033T3/da active
- 1992-02-07 ES ES92905817T patent/ES2271940T3/es not_active Expired - Lifetime
- 1992-02-07 WO PCT/FR1992/000111 patent/WO1992013949A1/fr active IP Right Grant
- 1992-02-07 AT AT06009929T patent/ATE504650T1/de not_active IP Right Cessation
- 1992-02-07 AT AT92905817T patent/ATE338134T1/de active
- 1992-02-07 EP EP06009929A patent/EP1721978B1/de not_active Expired - Lifetime
- 1992-02-07 EP EP92905817A patent/EP0529033B1/de not_active Expired - Lifetime
-
1995
- 1995-04-19 US US08/348,572 patent/US5817511A/en not_active Expired - Lifetime
-
1996
- 1996-03-22 US US08/620,467 patent/US5798231A/en not_active Expired - Lifetime
-
1998
- 1998-03-12 US US09/041,090 patent/US6114516A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU660660B2 (en) | 1995-07-06 |
DK0529033T3 (da) | 2007-01-08 |
US6114516A (en) | 2000-09-05 |
AU1360392A (en) | 1992-09-07 |
DE69233652T2 (de) | 2007-09-27 |
ATE504650T1 (de) | 2011-04-15 |
WO1992013949A1 (fr) | 1992-08-20 |
IE920413A1 (en) | 1992-08-12 |
US5817511A (en) | 1998-10-06 |
EP0529033B1 (de) | 2006-08-30 |
US5798231A (en) | 1998-08-25 |
CA2079879A1 (fr) | 1992-08-09 |
EP0529033A1 (de) | 1993-03-03 |
ES2271940T3 (es) | 2007-04-16 |
ATE338134T1 (de) | 2006-09-15 |
DE69233804D1 (de) | 2011-05-19 |
KR100242278B1 (ko) | 2000-02-01 |
CA2079879C (fr) | 2007-11-06 |
EP1721978B1 (de) | 2011-04-06 |
JPH05509234A (ja) | 1993-12-22 |
EP1721978A1 (de) | 2006-11-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69233652D1 (de) | Nukleotidsequenzen, die für die veränderlichen bereiche der alpha-ketten menschlicher t-zell-rezeptoren kodieren sowie ihre verwendungen | |
BR9007197A (pt) | Cadeia pesada,cadeia leve e molecula de anticorpo,sequencia de dna,vetor de clonagem,celula hospedeira,processos para produzir uma sequencia de anticorpo e um produto de anticorpo,composicao terapeutica e processo de terapia ou diagnose | |
DE69428214T2 (de) | Transformierender wachstumsfaktor alpha h1 | |
DE69024291D1 (de) | Rezeptoren für Tumornekrosisfaktor-alpha und -beta | |
DE69617440D1 (de) | Isolierte nukleinsäuremoleküle, peptide die mit hla-a2 moleküle (mhc) komplexe bilden, sowie deren verwendungen | |
CY1105687T1 (el) | Οικογενεια ανοσορυθμιστων που οριζονται ως υποδοχεις λευκοκυτταρων παρομοιοι με ανοσοσφαιρινες (lir) | |
ATE355074T1 (de) | Hybrid aus interferon-alpha und immunglobulin fc- fragment verbunden durch ein nicht immunogenes peptid | |
KR970705405A (ko) | 사람 케모킨 폴리펩타이드(Human Chemokine Polypeptides) | |
DK0669979T3 (da) | C-C CKR-1, kemokinreceptor | |
HUT63652A (en) | Process for producing cd44 surface protein variants, dna sequences encoding them and antibodies against them, as well as their application in diagnosis and therapy | |
ATE173023T1 (de) | Dna-sequenzen kodierend für das polypeptid gelonin | |
Suran et al. | N-terminal sequences of heavy and light chains of leopard shark immunoglobulins: evolutionary implications. | |
ATE252638T1 (de) | Das humane jtvi-gen überlappt mit dem pms2-gen | |
KR970070198A (ko) | 항-파스 재조합 항체 및 이에 대한 디엔아이 | |
AR010337A1 (es) | Acido nucleico aislado, molecula de acido nucleico, sonda, vector de expresion recombinante, celula, metodo para producir un polipeptido de h.pylori, metodo para detectar la presencia de un acido nucleico helicobacter, polipeptido de h.pylori aislado, proteina de fusion, formulacion para vacuna | |
JPWO2021202678A5 (de) | ||
Fellah et al. | Structure and diversity of the T-cell receptor α chain in the Mexican axolotl | |
KR860006484A (ko) | 단백질 또는 당단백질의 제조방법 | |
DE69332583T2 (de) | Maspin- ein neues serpin mit tumor unterdrückender aktivität | |
IT8821701A0 (it) | Dna plasmidico ricombinante ppr il2 19 codificante la sintesi dell'interleuchina 2 umana, metodo per la sua ingenierizzazione e ceppo del batterio escherichia coli vniigenetika vl 903 (ppr il2 19) producente interleuchina 2 umana che lo contiene |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |