ZA874482B - Method of chain combination - Google Patents

Method of chain combination

Info

Publication number
ZA874482B
ZA874482B ZA874482A ZA874482A ZA874482B ZA 874482 B ZA874482 B ZA 874482B ZA 874482 A ZA874482 A ZA 874482A ZA 874482 A ZA874482 A ZA 874482A ZA 874482 B ZA874482 B ZA 874482B
Authority
ZA
South Africa
Prior art keywords
chain combination
chain
combination
Prior art date
Application number
ZA874482A
Other languages
English (en)
Inventor
John Perry Burnier
Perry Burnier John
Paul Douglas Johnston
Douglas Johnston Paul
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of ZA874482B publication Critical patent/ZA874482B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/64Relaxins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/26Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ZA874482A 1986-06-23 1987-06-22 Method of chain combination ZA874482B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/877,819 US4835251A (en) 1986-06-23 1986-06-23 Method of chain combination

Publications (1)

Publication Number Publication Date
ZA874482B true ZA874482B (en) 1989-02-22

Family

ID=25370787

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA874482A ZA874482B (en) 1986-06-23 1987-06-22 Method of chain combination

Country Status (15)

Country Link
US (1) US4835251A (pt)
EP (1) EP0251615B1 (pt)
JP (1) JP2529693B2 (pt)
KR (1) KR960007604B1 (pt)
CN (1) CN1029784C (pt)
AU (1) AU617291B2 (pt)
CA (1) CA1336223C (pt)
DE (1) DE3783273T2 (pt)
DK (1) DK173649B1 (pt)
HU (1) HU205948B (pt)
IE (1) IE59683B1 (pt)
IL (1) IL82921A (pt)
PH (1) PH23407A (pt)
PT (1) PT85134B (pt)
ZA (1) ZA874482B (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5191063A (en) * 1989-05-02 1993-03-02 University Of Medicine And Dentistry Of New Jersey Production of biologically active polypeptides by treatment with an exogenous peptide sequence
CA2051375C (en) * 1989-05-04 2000-09-12 Dennis J. Henner Process and compositions for the isolation of human relaxin
US5478807A (en) * 1991-08-19 1995-12-26 Genentech, Inc. Use of relaxin in the treatment of bradycardia
US5166191A (en) * 1991-08-19 1992-11-24 Genentech, Inc. Use of relaxin in cardiovascular therapy
US5911997A (en) * 1995-06-07 1999-06-15 Connetics Corporation Relaxin-like factor and methods and uses thereof
US5612051A (en) * 1995-11-17 1997-03-18 Yue; Samuel K. Method of treating involuntary muscle dysfunction with relaxin hormone
US6709659B1 (en) * 1996-08-02 2004-03-23 Zymogenetics, Inc. Antibodies that bind testis-specific insulin homolog polypeptides
US5994148A (en) * 1997-06-23 1999-11-30 The Regents Of University Of California Method of predicting and enhancing success of IVF/ET pregnancy
US6251863B1 (en) 1998-09-08 2001-06-26 Samuel K. Yue Method of preventing and treating symptoms of aging and neurodegenerative dysfunctions with relaxin
US20050032683A1 (en) * 2000-10-04 2005-02-10 Amento Edward P. Methods of modulating apoptosis by administration of relaxin agonists or antagonists
US20050186526A1 (en) * 2002-11-01 2005-08-25 Bas Medical, Inc. Methods and systems for enabling and stabilizing tooth movement
AU2003903124A0 (en) * 2003-06-20 2003-07-10 Mark Del Borgo Analogues of heteromeric proteins
WO2005115435A2 (en) 2004-04-30 2005-12-08 Bas Medical, Inc. Methods and compositions for control of fetal growth via modulation of relaxin
US20060052304A1 (en) * 2004-09-02 2006-03-09 Bas Medical, Inc. Method for remodeling bone and related sutures
WO2007115414A1 (en) * 2006-04-11 2007-10-18 University Of Guelph Modified h2 relaxin for tumor suppression
GR1006759B (el) * 2008-12-22 2010-04-20 Χημικα Και Βιοφαρμακευτικα Εργαστηρια Πατρων Αε (Cbl-Patras) Εξελιγμενη χημικη μεθοδος συνθεσης της ανθρωπινης ρηλαξινης
GR1006941B (el) * 2009-06-01 2010-08-27 Χημικα Και Βιοφαρμακευτικα Εργαστηρια Πατρων Αε (Cbl-Patras), Πεπτιδικη συνθεση (peptide synthesis)
GR1007010B (el) 2009-10-08 2010-10-07 Χημικα Και Βιοφαρμακευτικα Εργαστηρια Πατρων Αε (Cbl-Patras), Ινσουλινοειδη πεπτιδια
MY162837A (en) 2010-08-17 2017-07-31 Ambrx Inc Modified relaxin polypeptides and their uses
US20160152679A1 (en) * 2012-05-24 2016-06-02 Angion Biomedica Corp. Relaxin-like compounds and uses thereof
US9381231B2 (en) 2012-10-09 2016-07-05 University Of Florida Research Foundation, Inc. Use of relaxin to restore maternal physiology in pregnancies conceived by assisted reproductive technologies
JP6289937B2 (ja) * 2014-02-27 2018-03-07 学校法人東海大学 リラキシンの製造方法
EP2946788A1 (en) 2014-05-23 2015-11-25 Immundiagnostik AG Method and composition for treating heart failure with preserved ejection fraction
JP2018532810A (ja) 2015-11-07 2018-11-08 マルチビア インコーポレイテッド がんの処置のための腫瘍抑制因子遺伝子治療および免疫チェックポイント治療を含む組成物
CN110381997A (zh) 2016-12-12 2019-10-25 茂体外尔公司 用于治疗和预防癌症和感染性疾病的包含病毒基因治疗和免疫检查点抑制剂的方法和组合物
CN112020510A (zh) 2018-03-19 2020-12-01 茂体外尔公司 包含用于治疗癌症的肿瘤抑制基因疗法和cd122/cd132激动剂的方法及组合物
KR20220031044A (ko) 2019-07-31 2022-03-11 일라이 릴리 앤드 캄파니 릴랙신 유사체 및 이를 사용하는 방법
WO2021113644A1 (en) 2019-12-05 2021-06-10 Multivir Inc. Combinations comprising a cd8+ t cell enhancer, an immune checkpoint inhibitor and radiotherapy for targeted and abscopal effects for the treatment of cancer
WO2021226439A2 (en) * 2020-05-08 2021-11-11 President And Fellows Of Harvard College Engineered relaxins and methods of use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL128599B1 (en) * 1980-03-27 1984-02-29 Lilly Co Eli Insulin obtaining method
US4421685A (en) * 1980-03-27 1983-12-20 Eli Lilly And Company Process for producing an insulin
US4656249A (en) * 1982-06-10 1987-04-07 Howard Florey Institute Of Experimental Physiology And Medicine Peptides with relaxin activity
ATE78042T1 (de) * 1982-08-12 1992-07-15 Florey Howard Inst Analoge des humanen relaxins.
AU562962B2 (en) * 1982-08-12 1987-06-25 Howard Florey Institute Of Experimental Physiology And Medicine Molecular cloning and characterisation of the gene sequence coding for human relaxin
NZ206534A (en) * 1982-12-13 1988-05-30 Florey Howard Inst Molecular cloning and characterisation of gene sequence coding for human relaxin
AU562713B2 (en) * 1982-12-13 1987-06-18 Howard Florey Institute Of Experimental Physiology And Medicine Cloning for human relaxin

Also Published As

Publication number Publication date
US4835251A (en) 1989-05-30
HUT44045A (en) 1988-01-28
IL82921A (en) 1992-01-15
DK313087D0 (da) 1987-06-19
CN87104447A (zh) 1988-02-10
IE871655L (en) 1987-12-23
AU617291B2 (en) 1991-11-28
HU205948B (en) 1992-07-28
DE3783273T2 (de) 1993-05-27
CN1029784C (zh) 1995-09-20
PT85134A (en) 1987-07-01
JPS6366198A (ja) 1988-03-24
DK313087A (da) 1987-12-24
EP0251615B1 (en) 1992-12-30
PT85134B (pt) 1990-03-30
DK173649B1 (da) 2001-05-21
PH23407A (en) 1989-07-26
EP0251615A2 (en) 1988-01-07
KR880000463A (ko) 1988-03-26
KR960007604B1 (ko) 1996-06-07
JP2529693B2 (ja) 1996-08-28
AU7462087A (en) 1987-12-24
EP0251615A3 (en) 1989-12-13
DE3783273D1 (de) 1993-02-11
CA1336223C (en) 1995-07-04
IE59683B1 (en) 1994-03-23

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