ZA8742B - Derivatives of decahydroquinoline,their preparation process,the preparation intermediates,their use as medicaments and the compositions containing them - Google Patents
Derivatives of decahydroquinoline,their preparation process,the preparation intermediates,their use as medicaments and the compositions containing themInfo
- Publication number
- ZA8742B ZA8742B ZA8742A ZA8742A ZA8742B ZA 8742 B ZA8742 B ZA 8742B ZA 8742 A ZA8742 A ZA 8742A ZA 8742 A ZA8742 A ZA 8742A ZA 8742 B ZA8742 B ZA 8742B
- Authority
- ZA
- South Africa
- Prior art keywords
- group
- preparation
- decahydroquinoline
- medicaments
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/40—Nitrogen atoms attached in position 8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8600354A FR2592879B1 (fr) | 1986-01-13 | 1986-01-13 | Nouveaux derives de la decahydroquinoleine, leur procede de preparation, les intermediaires de preparation, leur application a titre de medicaments et les compositions les renfermant |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA8742B true ZA8742B (en) | 1988-03-30 |
Family
ID=9331031
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA8742A ZA8742B (en) | 1986-01-13 | 1987-01-05 | Derivatives of decahydroquinoline,their preparation process,the preparation intermediates,their use as medicaments and the compositions containing them |
Country Status (16)
Country | Link |
---|---|
US (2) | US4816465A (es) |
EP (1) | EP0233793B1 (es) |
JP (1) | JPH07116156B2 (es) |
AT (1) | ATE74352T1 (es) |
AU (1) | AU597326B2 (es) |
CA (1) | CA1282784C (es) |
DE (1) | DE3777852D1 (es) |
DK (1) | DK168068B1 (es) |
ES (1) | ES2037098T3 (es) |
FR (1) | FR2592879B1 (es) |
GR (1) | GR3004250T3 (es) |
HU (1) | HU196593B (es) |
IE (1) | IE59794B1 (es) |
PT (1) | PT84091B (es) |
SU (1) | SU1598874A3 (es) |
ZA (1) | ZA8742B (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3770726D1 (de) * | 1986-08-12 | 1991-07-18 | Roussel Uclaf | Decahydrochinolinderivate, verfahren zu ihrer herstellung und zwischenprodukte davon, ihre verwendung als arzneimittel und ihre pharmazeutischen zusammensetzungen. |
FR2617481B1 (fr) * | 1987-07-03 | 1989-11-10 | Roussel Uclaf | Nouveaux derives de la tetrahydropyridine, leur procede de preparation et les intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
GB8804014D0 (en) * | 1988-02-23 | 1988-03-23 | Humphreys & Glasgow Ltd | Synthesis gas production |
JPH01308229A (ja) * | 1988-02-23 | 1989-12-12 | Glaxo Group Ltd | 複素環誘導体 |
DK247789A (da) * | 1988-05-23 | 1989-11-24 | Glaxo Group Ltd | Piperazinderivater |
GB8824400D0 (en) * | 1988-10-18 | 1988-11-23 | Glaxo Group Ltd | Chemical compounds |
AU661159B2 (en) * | 1992-07-15 | 1995-07-13 | Sumitomo Chemical Company, Limited | N-acyldihydroquinoline derivatives, a method for producing the same and their use as herbicides |
US5474673A (en) * | 1994-07-05 | 1995-12-12 | Ludlow; David J. | Top mounted biological filtration system for an aquarium |
US5646151A (en) * | 1996-03-08 | 1997-07-08 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
US5688955A (en) * | 1996-03-08 | 1997-11-18 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
US6057323A (en) * | 1996-03-08 | 2000-05-02 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
US6750216B2 (en) | 1996-03-08 | 2004-06-15 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
US6239154B1 (en) | 1996-03-08 | 2001-05-29 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
USRE38133E1 (en) * | 1996-03-08 | 2003-06-03 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
US5763445A (en) | 1996-03-08 | 1998-06-09 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
US6303611B1 (en) | 1996-03-08 | 2001-10-16 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
WO2001068604A2 (en) * | 2000-03-14 | 2001-09-20 | Sepracor, Inc. | 3-substituted piperidines comprising urea functionality, and methods of use thereof |
JP4629576B2 (ja) * | 2002-08-14 | 2011-02-09 | アボット・ラボラトリーズ | 中枢神経系活性剤であるアザビシクロ化合物 |
US7135484B2 (en) | 2002-08-14 | 2006-11-14 | Abbott Laboratories | Azabicyclic compounds are central nervous system active agents |
WO2019113419A1 (en) * | 2017-12-08 | 2019-06-13 | The Rockefeller University | Pyrano[3,4-b]pyrazine kappa opioid receptor ligands for treating addiction, pruritus, pain, and inflammation |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3056792A (en) * | 1958-06-04 | 1962-10-02 | Geschickter Fund Med Res | Unsymmetrical 1, 3-diamino-2-propanols |
GB1463582A (en) * | 1974-03-05 | 1977-02-02 | Wyeth John & Brother Ltd | Pyridine derivatives |
US4173636A (en) * | 1975-12-16 | 1979-11-06 | Labaz | Decahydroquinolines, pharmaceutical compositions and methods of use |
GB1515540A (en) * | 1975-12-16 | 1978-06-28 | Labaz | 4-amino-trans-decahydroquinoline derivatives |
US4098904A (en) * | 1976-11-12 | 1978-07-04 | The Upjohn Company | Analgesic n-(2-aminocycloaliphatic)benzamides |
US4145435A (en) * | 1976-11-12 | 1979-03-20 | The Upjohn Company | 2-aminocycloaliphatic amide compounds |
US4359476A (en) * | 1981-04-09 | 1982-11-16 | The Upjohn Company | Adjacently substituted cycloalkane-amide analgesics |
DE3770726D1 (de) * | 1986-08-12 | 1991-07-18 | Roussel Uclaf | Decahydrochinolinderivate, verfahren zu ihrer herstellung und zwischenprodukte davon, ihre verwendung als arzneimittel und ihre pharmazeutischen zusammensetzungen. |
DE3633977A1 (de) * | 1986-10-06 | 1988-04-07 | Cassella Ag | Tetrahydrochinolinderivate, ein verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen |
FR2617164B1 (fr) * | 1987-06-25 | 1989-11-10 | Roussel Uclaf | Nouveaux derives de la decahydroquinoleine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
JPH094481A (ja) * | 1996-07-18 | 1997-01-07 | Yanmar Agricult Equip Co Ltd | 走行作業機におけるエンジン出力制御装置 |
-
1986
- 1986-01-13 FR FR8600354A patent/FR2592879B1/fr not_active Expired
-
1987
- 1987-01-05 ZA ZA8742A patent/ZA8742B/xx unknown
- 1987-01-09 AT AT87400033T patent/ATE74352T1/de not_active IP Right Cessation
- 1987-01-09 ES ES198787400033T patent/ES2037098T3/es not_active Expired - Lifetime
- 1987-01-09 EP EP87400033A patent/EP0233793B1/fr not_active Expired - Lifetime
- 1987-01-09 DE DE8787400033T patent/DE3777852D1/de not_active Expired - Fee Related
- 1987-01-12 SU SU874028897A patent/SU1598874A3/ru active
- 1987-01-12 JP JP62003424A patent/JPH07116156B2/ja not_active Expired - Lifetime
- 1987-01-12 PT PT84091A patent/PT84091B/pt not_active IP Right Cessation
- 1987-01-12 DK DK012087A patent/DK168068B1/da not_active IP Right Cessation
- 1987-01-12 IE IE6887A patent/IE59794B1/en not_active IP Right Cessation
- 1987-01-12 AU AU67476/87A patent/AU597326B2/en not_active Ceased
- 1987-01-13 HU HU8799A patent/HU196593B/hu not_active IP Right Cessation
- 1987-01-13 CA CA000527242A patent/CA1282784C/fr not_active Expired - Fee Related
- 1987-01-13 US US07/002,778 patent/US4816465A/en not_active Expired - Fee Related
-
1988
- 1988-07-11 US US07/217,834 patent/US4968700A/en not_active Expired - Fee Related
-
1992
- 1992-04-02 GR GR910402210T patent/GR3004250T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA1282784C (fr) | 1991-04-09 |
SU1598874A3 (ru) | 1990-10-07 |
ES2037098T3 (es) | 1993-06-16 |
GR3004250T3 (es) | 1993-03-31 |
DK168068B1 (da) | 1994-01-31 |
ATE74352T1 (de) | 1992-04-15 |
IE870068L (en) | 1987-07-13 |
EP0233793A3 (en) | 1989-04-19 |
JPH07116156B2 (ja) | 1995-12-13 |
PT84091A (fr) | 1987-02-01 |
FR2592879B1 (fr) | 1988-04-29 |
FR2592879A1 (fr) | 1987-07-17 |
HUT43570A (en) | 1987-11-30 |
EP0233793A2 (fr) | 1987-08-26 |
HU196593B (en) | 1988-12-28 |
JPS62167767A (ja) | 1987-07-24 |
EP0233793B1 (fr) | 1992-04-01 |
PT84091B (pt) | 1989-07-31 |
DK12087A (da) | 1987-07-14 |
DK12087D0 (da) | 1987-01-12 |
AU597326B2 (en) | 1990-05-31 |
DE3777852D1 (de) | 1992-05-07 |
US4968700A (en) | 1990-11-06 |
US4816465A (en) | 1989-03-28 |
AU6747687A (en) | 1987-07-16 |
IE59794B1 (en) | 1994-04-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA8742B (en) | Derivatives of decahydroquinoline,their preparation process,the preparation intermediates,their use as medicaments and the compositions containing them | |
DE3271269D1 (en) | Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same | |
ES8506677A1 (es) | Un procedimiento para la preparacion de nuevos derivados de 8-cloro71,5-benzotiazepina. | |
PT87277A (pt) | Process for the preparation of new bicyclic compounds and pharmaceutical compositions comprising same | |
DE3267429D1 (en) | 1-phenyl-2-aminocarbonylindole compounds, process and intermediates for their preparation and medicines containing them | |
PT87578A (pt) | Process for the preparation of new alkanesulfonanilide derivatives and of pharmaceutical composition comprising the same | |
AU8295887A (en) | New indane derivatives, the process for preparing them and the new intermediates thereby obtained, their application as medicinal products and the compositions containing them | |
ES457988A1 (es) | Un procedimiento de preparacion de un derivado de fenilpipe-razina. | |
SE8903312D0 (sv) | New 2-carbonyl substituted n,n'-di-(trimethoxybenzol)piperazines, process for preparing the same and therapeutical compounds containing them | |
DE3264556D1 (en) | Sulfimines, their salts and their preparation, and pharmaceutical compositions containing them | |
SE8400629D0 (sv) | Novel basic oxime ethers and a process for preparing same | |
ATE29133T1 (de) | Troponon-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung. | |
ES8405372A1 (es) | Un procedimiento para preparar un enantiomero puro de un fenilazacicloalcano sustituido. | |
GB1093977A (en) | 4-quinazolinone derivatives | |
ES8105713A1 (es) | Un procedimiento para la preparacion de los enatiomeros levogiro y dextrogiro de la 1-ciclopropil-metil-4-(3-metoxi-5h- dibenzo (a,d) ciclohepten-5-iliden) piperidina | |
ES8403471A1 (es) | Un procedimiento para preparar nuevos compuestos de cromanona. |