DK12087D0 - Decahydroquinolinderivater, deres fremstilling og anvendelse samt praeparater med indhold deraf - Google Patents

Decahydroquinolinderivater, deres fremstilling og anvendelse samt praeparater med indhold deraf

Info

Publication number
DK12087D0
DK12087D0 DK012087A DK12087A DK12087D0 DK 12087 D0 DK12087 D0 DK 12087D0 DK 012087 A DK012087 A DK 012087A DK 12087 A DK12087 A DK 12087A DK 12087 D0 DK12087 D0 DK 12087D0
Authority
DK
Denmark
Prior art keywords
group
alkyl
carbon atoms
substituted
heterocycle
Prior art date
Application number
DK012087A
Other languages
English (en)
Other versions
DK168068B1 (da
DK12087A (da
Inventor
Francois Clemence
Francoise Delevallee
Michel Fortin
Martret Odile Le
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of DK12087D0 publication Critical patent/DK12087D0/da
Publication of DK12087A publication Critical patent/DK12087A/da
Application granted granted Critical
Publication of DK168068B1 publication Critical patent/DK168068B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/40—Nitrogen atoms attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)
DK012087A 1986-01-13 1987-01-12 Decahydroquinolinderivater, en fremsgangsmaade til deres fremstilling samt laegemidler med indhold deraf DK168068B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8600354A FR2592879B1 (fr) 1986-01-13 1986-01-13 Nouveaux derives de la decahydroquinoleine, leur procede de preparation, les intermediaires de preparation, leur application a titre de medicaments et les compositions les renfermant
FR8600354 1986-01-13

Publications (3)

Publication Number Publication Date
DK12087D0 true DK12087D0 (da) 1987-01-12
DK12087A DK12087A (da) 1987-07-14
DK168068B1 DK168068B1 (da) 1994-01-31

Family

ID=9331031

Family Applications (1)

Application Number Title Priority Date Filing Date
DK012087A DK168068B1 (da) 1986-01-13 1987-01-12 Decahydroquinolinderivater, en fremsgangsmaade til deres fremstilling samt laegemidler med indhold deraf

Country Status (16)

Country Link
US (2) US4816465A (da)
EP (1) EP0233793B1 (da)
JP (1) JPH07116156B2 (da)
AT (1) ATE74352T1 (da)
AU (1) AU597326B2 (da)
CA (1) CA1282784C (da)
DE (1) DE3777852D1 (da)
DK (1) DK168068B1 (da)
ES (1) ES2037098T3 (da)
FR (1) FR2592879B1 (da)
GR (1) GR3004250T3 (da)
HU (1) HU196593B (da)
IE (1) IE59794B1 (da)
PT (1) PT84091B (da)
SU (1) SU1598874A3 (da)
ZA (1) ZA8742B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3770726D1 (de) * 1986-08-12 1991-07-18 Roussel Uclaf Decahydrochinolinderivate, verfahren zu ihrer herstellung und zwischenprodukte davon, ihre verwendung als arzneimittel und ihre pharmazeutischen zusammensetzungen.
FR2617481B1 (fr) * 1987-07-03 1989-11-10 Roussel Uclaf Nouveaux derives de la tetrahydropyridine, leur procede de preparation et les intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
JPH01308229A (ja) * 1988-02-23 1989-12-12 Glaxo Group Ltd 複素環誘導体
GB8804014D0 (en) * 1988-02-23 1988-03-23 Humphreys & Glasgow Ltd Synthesis gas production
FI892468A (fi) * 1988-05-23 1989-11-24 Glaxo Group Ltd Piperazinderivat.
GB8824400D0 (en) * 1988-10-18 1988-11-23 Glaxo Group Ltd Chemical compounds
TW234124B (da) * 1992-07-15 1994-11-11 Sumitomo Chemical Co
US5474673A (en) * 1994-07-05 1995-12-12 Ludlow; David J. Top mounted biological filtration system for an aquarium
US6057323A (en) * 1996-03-08 2000-05-02 Adolor Corporation Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith
US6750216B2 (en) 1996-03-08 2004-06-15 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
US6303611B1 (en) 1996-03-08 2001-10-16 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
US6239154B1 (en) 1996-03-08 2001-05-29 Adolor Corporation Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith
US5688955A (en) * 1996-03-08 1997-11-18 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
USRE38133E1 (en) * 1996-03-08 2003-06-03 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
US5646151A (en) * 1996-03-08 1997-07-08 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
US5763445A (en) 1996-03-08 1998-06-09 Adolor Corporation Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith
WO2001068604A2 (en) * 2000-03-14 2001-09-20 Sepracor, Inc. 3-substituted piperidines comprising urea functionality, and methods of use thereof
US7135484B2 (en) 2002-08-14 2006-11-14 Abbott Laboratories Azabicyclic compounds are central nervous system active agents
CA2495589A1 (en) * 2002-08-14 2004-02-26 Abbott Laboratories Azabicyclic compounds are central nervous system active agents
JP2021505671A (ja) * 2017-12-08 2021-02-18 ザ ロックフェラー ユニバーシティＴｈｅ Ｒｏｃｋｅｆｅｌｌｅｒ Ｕｎｉｖｅｒｓｉｔｙ 中毒症、掻痒症、疼痛および炎症治療用ピラノ［３，４−ｂ］ピラジンカッパオピオイド受容体リガンド

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3056792A (en) * 1958-06-04 1962-10-02 Geschickter Fund Med Res Unsymmetrical 1, 3-diamino-2-propanols
GB1463582A (en) * 1974-03-05 1977-02-02 Wyeth John & Brother Ltd Pyridine derivatives
US4173636A (en) * 1975-12-16 1979-11-06 Labaz Decahydroquinolines, pharmaceutical compositions and methods of use
GB1515540A (en) * 1975-12-16 1978-06-28 Labaz 4-amino-trans-decahydroquinoline derivatives
US4145435A (en) * 1976-11-12 1979-03-20 The Upjohn Company 2-aminocycloaliphatic amide compounds
US4098904A (en) * 1976-11-12 1978-07-04 The Upjohn Company Analgesic n-(2-aminocycloaliphatic)benzamides
US4359476A (en) * 1981-04-09 1982-11-16 The Upjohn Company Adjacently substituted cycloalkane-amide analgesics
DE3770726D1 (de) * 1986-08-12 1991-07-18 Roussel Uclaf Decahydrochinolinderivate, verfahren zu ihrer herstellung und zwischenprodukte davon, ihre verwendung als arzneimittel und ihre pharmazeutischen zusammensetzungen.
DE3633977A1 (de) * 1986-10-06 1988-04-07 Cassella Ag Tetrahydrochinolinderivate, ein verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen
FR2617164B1 (fr) * 1987-06-25 1989-11-10 Roussel Uclaf Nouveaux derives de la decahydroquinoleine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
JPH094481A (ja) * 1996-07-18 1997-01-07 Yanmar Agricult Equip Co Ltd 走行作業機におけるエンジン出力制御装置

Also Published As

Publication number Publication date
JPS62167767A (ja) 1987-07-24
GR3004250T3 (da) 1993-03-31
DK168068B1 (da) 1994-01-31
DK12087A (da) 1987-07-14
IE59794B1 (en) 1994-04-06
FR2592879A1 (fr) 1987-07-17
IE870068L (en) 1987-07-13
ES2037098T3 (es) 1993-06-16
EP0233793A2 (fr) 1987-08-26
DE3777852D1 (de) 1992-05-07
HU196593B (en) 1988-12-28
CA1282784C (fr) 1991-04-09
US4816465A (en) 1989-03-28
EP0233793A3 (en) 1989-04-19
PT84091A (fr) 1987-02-01
ZA8742B (en) 1988-03-30
US4968700A (en) 1990-11-06
HUT43570A (en) 1987-11-30
AU597326B2 (en) 1990-05-31
SU1598874A3 (ru) 1990-10-07
AU6747687A (en) 1987-07-16
JPH07116156B2 (ja) 1995-12-13
PT84091B (pt) 1989-07-31
EP0233793B1 (fr) 1992-04-01
FR2592879B1 (fr) 1988-04-29
ATE74352T1 (de) 1992-04-15

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed