DE3483798D1 - Dihydrodibenzocycloheptylidenethylamin-derivate. - Google Patents

Dihydrodibenzocycloheptylidenethylamin-derivate.

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Publication number
DE3483798D1
DE3483798D1 DE8484108424T DE3483798T DE3483798D1 DE 3483798 D1 DE3483798 D1 DE 3483798D1 DE 8484108424 T DE8484108424 T DE 8484108424T DE 3483798 T DE3483798 T DE 3483798T DE 3483798 D1 DE3483798 D1 DE 3483798D1
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Prior art keywords
derivatives
pains
treatment
pathological conditions
dihydrodibenzocycloheptylidenethylamine
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DE8484108424T
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English (en)
Inventor
Xavier D Cirera
Romeo R Andreoli
Pedro P Lloveras
Leonida Bruseghini
Jose P Irrure
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Sociedad Espanola de Especialidades Farmaco Terapeuticas SA
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Sociedad Espanola de Especialidades Farmaco Terapeuticas SA
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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
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    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
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    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
DE8484108424T 1983-08-02 1984-07-17 Dihydrodibenzocycloheptylidenethylamin-derivate. Expired - Fee Related DE3483798D1 (de)

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ES524680A ES524680A0 (es) 1983-08-02 1983-08-02 Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina.

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EP (2) EP0132764B1 (de)
JP (1) JPH0625091B2 (de)
KR (1) KR900007198B1 (de)
AT (1) ATE59632T1 (de)
AU (1) AU580963B2 (de)
CA (1) CA1243018A (de)
DE (1) DE3483798D1 (de)
ES (1) ES524680A0 (de)
NZ (1) NZ208691A (de)
ZA (1) ZA845940B (de)

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ES524680A0 (es) * 1983-08-02 1984-12-16 Espanola Farma Therapeut Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina.
US4882351A (en) * 1987-10-14 1989-11-21 Roussel Uclaf Tricyclic compounds
IT1222986B (it) * 1987-10-23 1990-09-12 Texcontor Ets Derivati dell'efedrina esterificata aventi attivita' antiulcera prolungata nel tempo
US5508280A (en) * 1990-05-18 1996-04-16 Merrell Pharmaceuticals, Inc. 5H-Dibenzo (A,D) cycloheptenes as muscarinic receptor antagonists
DE69127549T2 (de) * 1990-05-18 1998-04-23 Merrell Pharma Inc 5h-dibenzo[a,d]cycloheptene als muscarinic-rezeptor-antagonist
JP2574733Y2 (ja) * 1991-09-04 1998-06-18 松下電器産業株式会社 車両用ハーネス案内装置
ES2194217T3 (es) * 1996-10-04 2003-11-16 Novo Nordisk As Spperazinas 1,4-disustituidas.
US6613905B1 (en) * 1998-01-21 2003-09-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US7541365B2 (en) 2001-11-21 2009-06-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
TWI291467B (en) 2002-11-13 2007-12-21 Millennium Pharm Inc CCR1 antagonists and methods of use therefor
WO2014108449A1 (en) 2013-01-08 2014-07-17 Atrogi Ab A screening method, a kit, a method of treatment and a compound for use in a method of treatment
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses

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EP0132764A2 (de) 1985-02-13
AU3131684A (en) 1985-02-07
KR900007198B1 (ko) 1990-10-05
EP0132764B1 (de) 1991-01-02
US4835179A (en) 1989-05-30
JPH0625091B2 (ja) 1994-04-06
US5112826A (en) 1992-05-12
EP0132764A3 (en) 1985-12-04
EP0357956A3 (de) 1990-08-29
ATE59632T1 (de) 1991-01-15
US4835156A (en) 1989-05-30
EP0357956A2 (de) 1990-03-14
CA1243018A (en) 1988-10-11
ES8502099A1 (es) 1984-12-16
AU580963B2 (en) 1989-02-09
ES524680A0 (es) 1984-12-16
NZ208691A (en) 1989-06-28
JPS60126265A (ja) 1985-07-05
ZA845940B (en) 1986-08-27
KR850002261A (ko) 1985-05-10

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