DK12087A - Decahydroquinolinderivater, deres fremstilling og anvendelse samt praeparater med indhold deraf - Google Patents
Decahydroquinolinderivater, deres fremstilling og anvendelse samt praeparater med indhold derafInfo
- Publication number
- DK12087A DK12087A DK012087A DK12087A DK12087A DK 12087 A DK12087 A DK 12087A DK 012087 A DK012087 A DK 012087A DK 12087 A DK12087 A DK 12087A DK 12087 A DK12087 A DK 12087A
- Authority
- DK
- Denmark
- Prior art keywords
- group
- alkyl
- carbon atoms
- substituted
- heterocycle
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/40—Nitrogen atoms attached in position 8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8600354A FR2592879B1 (fr) | 1986-01-13 | 1986-01-13 | Nouveaux derives de la decahydroquinoleine, leur procede de preparation, les intermediaires de preparation, leur application a titre de medicaments et les compositions les renfermant |
FR8600354 | 1986-01-13 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK12087D0 DK12087D0 (da) | 1987-01-12 |
DK12087A true DK12087A (da) | 1987-07-14 |
DK168068B1 DK168068B1 (da) | 1994-01-31 |
Family
ID=9331031
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK012087A DK168068B1 (da) | 1986-01-13 | 1987-01-12 | Decahydroquinolinderivater, en fremsgangsmaade til deres fremstilling samt laegemidler med indhold deraf |
Country Status (16)
Country | Link |
---|---|
US (2) | US4816465A (da) |
EP (1) | EP0233793B1 (da) |
JP (1) | JPH07116156B2 (da) |
AT (1) | ATE74352T1 (da) |
AU (1) | AU597326B2 (da) |
CA (1) | CA1282784C (da) |
DE (1) | DE3777852D1 (da) |
DK (1) | DK168068B1 (da) |
ES (1) | ES2037098T3 (da) |
FR (1) | FR2592879B1 (da) |
GR (1) | GR3004250T3 (da) |
HU (1) | HU196593B (da) |
IE (1) | IE59794B1 (da) |
PT (1) | PT84091B (da) |
SU (1) | SU1598874A3 (da) |
ZA (1) | ZA8742B (da) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3770726D1 (de) * | 1986-08-12 | 1991-07-18 | Roussel Uclaf | Decahydrochinolinderivate, verfahren zu ihrer herstellung und zwischenprodukte davon, ihre verwendung als arzneimittel und ihre pharmazeutischen zusammensetzungen. |
FR2617481B1 (fr) * | 1987-07-03 | 1989-11-10 | Roussel Uclaf | Nouveaux derives de la tetrahydropyridine, leur procede de preparation et les intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
GB8804014D0 (en) * | 1988-02-23 | 1988-03-23 | Humphreys & Glasgow Ltd | Synthesis gas production |
JPH01308229A (ja) * | 1988-02-23 | 1989-12-12 | Glaxo Group Ltd | 複素環誘導体 |
DK247789A (da) * | 1988-05-23 | 1989-11-24 | Glaxo Group Ltd | Piperazinderivater |
GB8824400D0 (en) * | 1988-10-18 | 1988-11-23 | Glaxo Group Ltd | Chemical compounds |
AU661159B2 (en) * | 1992-07-15 | 1995-07-13 | Sumitomo Chemical Company, Limited | N-acyldihydroquinoline derivatives, a method for producing the same and their use as herbicides |
US5474673A (en) * | 1994-07-05 | 1995-12-12 | Ludlow; David J. | Top mounted biological filtration system for an aquarium |
US5646151A (en) * | 1996-03-08 | 1997-07-08 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
US5688955A (en) * | 1996-03-08 | 1997-11-18 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
US6057323A (en) * | 1996-03-08 | 2000-05-02 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
US6750216B2 (en) | 1996-03-08 | 2004-06-15 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
US6239154B1 (en) | 1996-03-08 | 2001-05-29 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
USRE38133E1 (en) * | 1996-03-08 | 2003-06-03 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
US5763445A (en) | 1996-03-08 | 1998-06-09 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
US6303611B1 (en) | 1996-03-08 | 2001-10-16 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
WO2001068604A2 (en) * | 2000-03-14 | 2001-09-20 | Sepracor, Inc. | 3-substituted piperidines comprising urea functionality, and methods of use thereof |
JP4629576B2 (ja) * | 2002-08-14 | 2011-02-09 | アボット・ラボラトリーズ | 中枢神経系活性剤であるアザビシクロ化合物 |
US7135484B2 (en) | 2002-08-14 | 2006-11-14 | Abbott Laboratories | Azabicyclic compounds are central nervous system active agents |
WO2019113419A1 (en) * | 2017-12-08 | 2019-06-13 | The Rockefeller University | Pyrano[3,4-b]pyrazine kappa opioid receptor ligands for treating addiction, pruritus, pain, and inflammation |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3056792A (en) * | 1958-06-04 | 1962-10-02 | Geschickter Fund Med Res | Unsymmetrical 1, 3-diamino-2-propanols |
GB1463582A (en) * | 1974-03-05 | 1977-02-02 | Wyeth John & Brother Ltd | Pyridine derivatives |
US4173636A (en) * | 1975-12-16 | 1979-11-06 | Labaz | Decahydroquinolines, pharmaceutical compositions and methods of use |
GB1515540A (en) * | 1975-12-16 | 1978-06-28 | Labaz | 4-amino-trans-decahydroquinoline derivatives |
US4098904A (en) * | 1976-11-12 | 1978-07-04 | The Upjohn Company | Analgesic n-(2-aminocycloaliphatic)benzamides |
US4145435A (en) * | 1976-11-12 | 1979-03-20 | The Upjohn Company | 2-aminocycloaliphatic amide compounds |
US4359476A (en) * | 1981-04-09 | 1982-11-16 | The Upjohn Company | Adjacently substituted cycloalkane-amide analgesics |
DE3770726D1 (de) * | 1986-08-12 | 1991-07-18 | Roussel Uclaf | Decahydrochinolinderivate, verfahren zu ihrer herstellung und zwischenprodukte davon, ihre verwendung als arzneimittel und ihre pharmazeutischen zusammensetzungen. |
DE3633977A1 (de) * | 1986-10-06 | 1988-04-07 | Cassella Ag | Tetrahydrochinolinderivate, ein verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen |
FR2617164B1 (fr) * | 1987-06-25 | 1989-11-10 | Roussel Uclaf | Nouveaux derives de la decahydroquinoleine, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
JPH094481A (ja) * | 1996-07-18 | 1997-01-07 | Yanmar Agricult Equip Co Ltd | 走行作業機におけるエンジン出力制御装置 |
-
1986
- 1986-01-13 FR FR8600354A patent/FR2592879B1/fr not_active Expired
-
1987
- 1987-01-05 ZA ZA8742A patent/ZA8742B/xx unknown
- 1987-01-09 AT AT87400033T patent/ATE74352T1/de not_active IP Right Cessation
- 1987-01-09 ES ES198787400033T patent/ES2037098T3/es not_active Expired - Lifetime
- 1987-01-09 EP EP87400033A patent/EP0233793B1/fr not_active Expired - Lifetime
- 1987-01-09 DE DE8787400033T patent/DE3777852D1/de not_active Expired - Fee Related
- 1987-01-12 SU SU874028897A patent/SU1598874A3/ru active
- 1987-01-12 JP JP62003424A patent/JPH07116156B2/ja not_active Expired - Lifetime
- 1987-01-12 PT PT84091A patent/PT84091B/pt not_active IP Right Cessation
- 1987-01-12 DK DK012087A patent/DK168068B1/da not_active IP Right Cessation
- 1987-01-12 IE IE6887A patent/IE59794B1/en not_active IP Right Cessation
- 1987-01-12 AU AU67476/87A patent/AU597326B2/en not_active Ceased
- 1987-01-13 HU HU8799A patent/HU196593B/hu not_active IP Right Cessation
- 1987-01-13 CA CA000527242A patent/CA1282784C/fr not_active Expired - Fee Related
- 1987-01-13 US US07/002,778 patent/US4816465A/en not_active Expired - Fee Related
-
1988
- 1988-07-11 US US07/217,834 patent/US4968700A/en not_active Expired - Fee Related
-
1992
- 1992-04-02 GR GR910402210T patent/GR3004250T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA1282784C (fr) | 1991-04-09 |
SU1598874A3 (ru) | 1990-10-07 |
ES2037098T3 (es) | 1993-06-16 |
GR3004250T3 (da) | 1993-03-31 |
DK168068B1 (da) | 1994-01-31 |
ATE74352T1 (de) | 1992-04-15 |
IE870068L (en) | 1987-07-13 |
EP0233793A3 (en) | 1989-04-19 |
JPH07116156B2 (ja) | 1995-12-13 |
PT84091A (fr) | 1987-02-01 |
FR2592879B1 (fr) | 1988-04-29 |
FR2592879A1 (fr) | 1987-07-17 |
HUT43570A (en) | 1987-11-30 |
EP0233793A2 (fr) | 1987-08-26 |
HU196593B (en) | 1988-12-28 |
JPS62167767A (ja) | 1987-07-24 |
EP0233793B1 (fr) | 1992-04-01 |
PT84091B (pt) | 1989-07-31 |
ZA8742B (en) | 1988-03-30 |
DK12087D0 (da) | 1987-01-12 |
AU597326B2 (en) | 1990-05-31 |
DE3777852D1 (de) | 1992-05-07 |
US4968700A (en) | 1990-11-06 |
US4816465A (en) | 1989-03-28 |
AU6747687A (en) | 1987-07-16 |
IE59794B1 (en) | 1994-04-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PBP | Patent lapsed |