DK677487D0 - Indanderivater, deres fremstilling og laegemiddel med indhold deraf - Google Patents

Indanderivater, deres fremstilling og laegemiddel med indhold deraf

Info

Publication number
DK677487D0
DK677487D0 DK677487A DK677487A DK677487D0 DK 677487 D0 DK677487 D0 DK 677487D0 DK 677487 A DK677487 A DK 677487A DK 677487 A DK677487 A DK 677487A DK 677487 D0 DK677487 D0 DK 677487D0
Authority
DK
Denmark
Prior art keywords
carbon atoms
alkyl
group
hydrogen
alkoxy
Prior art date
Application number
DK677487A
Other languages
English (en)
Other versions
DK168992B1 (da
DK677487A (da
Inventor
Francois Clemence
Francoise Delevallee
Michel Fortin
Odile Le Martret
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of DK677487D0 publication Critical patent/DK677487D0/da
Publication of DK677487A publication Critical patent/DK677487A/da
Application granted granted Critical
Publication of DK168992B1 publication Critical patent/DK168992B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Indole Compounds (AREA)
DK677487A 1986-12-23 1987-12-22 Indanderivater, en fremgangsmåde til deres fremstilling og lægemidler med indhold deraf DK168992B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8618026 1986-12-23
FR8618026A FR2608598B1 (fr) 1986-12-23 1986-12-23 Nouveaux derives de l'indane, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions les renfermant

Publications (3)

Publication Number Publication Date
DK677487D0 true DK677487D0 (da) 1987-12-22
DK677487A DK677487A (da) 1988-06-24
DK168992B1 DK168992B1 (da) 1994-07-25

Family

ID=9342194

Family Applications (1)

Application Number Title Priority Date Filing Date
DK677487A DK168992B1 (da) 1986-12-23 1987-12-22 Indanderivater, en fremgangsmåde til deres fremstilling og lægemidler med indhold deraf

Country Status (14)

Country Link
US (1) US4888355A (da)
EP (1) EP0272982B1 (da)
JP (1) JP2512314B2 (da)
AT (1) ATE62663T1 (da)
AU (1) AU615171B2 (da)
CA (1) CA1299578C (da)
DE (1) DE3769451D1 (da)
DK (1) DK168992B1 (da)
ES (1) ES2028902T3 (da)
FR (1) FR2608598B1 (da)
GR (1) GR3002186T3 (da)
HU (1) HU199816B (da)
IE (1) IE60703B1 (da)
ZA (1) ZA879664B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3781627T2 (de) * 1986-08-21 1993-05-06 Roussel Uclaf Indanderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, diese enthaltende pharmazeutische zusammensetzungen und erhaltene zwischenprodukte.
DK626889A (da) * 1988-12-16 1990-06-17 Roussel Uclaf Indanderivater, deres fremstilling samt laegemidler med indhold deraf
US5416118A (en) * 1992-04-09 1995-05-16 Schering Corporation Bicyclic amides as inhibitors of acyl-coenzyme A: cholesterol acyl transferase
US5599985A (en) * 1993-09-14 1997-02-04 Sepracor, Inc. Optically pure 1-amido-2-indanols
WO1995030644A1 (en) * 1994-05-10 1995-11-16 The Wellcome Foundation Limited Amide derivatives and their therapeutic use
US5859043A (en) * 1996-06-11 1999-01-12 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Method for maintaining kidney function during surgery or severe trauma under general anesthesia
US6468971B1 (en) 1997-03-05 2002-10-22 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Maintaining kidney function during surgery or trauma
CN1731993A (zh) * 2002-11-01 2006-02-08 维洛药品公司 苯并呋喃化合物、组合物以及治疗和预防丙型肝炎病毒感染及相关疾病的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923813A (en) * 1969-12-19 1975-12-02 Christiaens Sa A Derivatives of 2-aminoindanes
US4098904A (en) * 1976-11-12 1978-07-04 The Upjohn Company Analgesic n-(2-aminocycloaliphatic)benzamides
US4466977A (en) * 1981-04-09 1984-08-21 The Upjohn Company N-[2-Amino(oxy- or thia- group-substituted-cycloaliphatic)]benzeneacetamides and -benzamide analgesics
US4359476A (en) * 1981-04-09 1982-11-16 The Upjohn Company Adjacently substituted cycloalkane-amide analgesics
US4438130A (en) * 1981-11-12 1984-03-20 The Upjohn Company Analgesic 1-oxa-, aza- and thia-spirocyclic compounds
US4560767A (en) * 1983-06-17 1985-12-24 The Upjohn Company N-(2-amino-cycloalkenyl)benzeneacetamide and -benzamide analgesics and tritiated kappa agonists therefrom
US4656182A (en) * 1983-12-06 1987-04-07 Warner-Lambert Company Substituted trans-1,2-diaminocyclohexyl amide compounds
DE3781627T2 (de) * 1986-08-21 1993-05-06 Roussel Uclaf Indanderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, diese enthaltende pharmazeutische zusammensetzungen und erhaltene zwischenprodukte.
US4876269A (en) * 1986-09-10 1989-10-24 E. I. Du Pont De Nemours And Company Benoz-fused cycloalkane trans-1,2-diamine derivatives

Also Published As

Publication number Publication date
JP2512314B2 (ja) 1996-07-03
AU8295887A (en) 1988-06-23
DE3769451D1 (de) 1991-05-23
HUT45965A (en) 1988-09-28
EP0272982A2 (fr) 1988-06-29
FR2608598A1 (fr) 1988-06-24
ES2028902T3 (es) 1992-07-16
JPS63264445A (ja) 1988-11-01
AU615171B2 (en) 1991-09-26
IE60703B1 (en) 1994-08-10
US4888355A (en) 1989-12-19
FR2608598B1 (fr) 1989-04-14
ZA879664B (en) 1989-02-22
DK168992B1 (da) 1994-07-25
HU199816B (en) 1990-03-28
ATE62663T1 (de) 1991-05-15
CA1299578C (fr) 1992-04-28
EP0272982A3 (en) 1989-11-08
GR3002186T3 (en) 1992-12-30
EP0272982B1 (fr) 1991-04-17
DK677487A (da) 1988-06-24
IE873495L (en) 1988-06-23

Similar Documents

Publication Publication Date Title
EP0487502A3 (en) Pharmaceutically active aryl-substituted amine derivatives
DK12087A (da) Decahydroquinolinderivater, deres fremstilling og anvendelse samt praeparater med indhold deraf
BG97221A (bg) Ортозаместени бифениламидини и бифенилизанидини и съдържащите ги антидиабетични или хипогликемични средства
DK677487A (da) Indanderivater, deres fremstilling og laegemiddel med indhold deraf
DK327286A (da) Indolcarboxamidderivater og salte deraf, deres fremstilling og anvendelse som laegemidler samt mellemprodukter til deres fremstilling
NO890440D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive isokinolinderivater.
DK391182A (da) Heterocycliske forbindelser, deres fremstilling og anvendelse
IL59489A0 (en) Phenyl piperazine derivatives,their preparation and pharmaceutical compositions containing them
DK160486C (da) N-(4-amino-2,2-diphenyl-butyl)- eller n-(3-amino-2,2-diphenyl-propyl) urinstofforbindelser, fremgangsmaade til fremstilling af disse, samt en farmaceutisk komposition
DK540684A (da) Benzoquinoliziner
ATE88467T1 (de) Pharmakologisch aktive alkylol-derivate.
ES2003086A6 (es) Procedimiento de obtencion de tienoquinolicinsulfonamidas
ES8105309A1 (es) Un procedimiento para la preparacion de nuevos derivados de cromano.
ES8200887A1 (es) Procedimiento para la preparacion de nuevas 2-(perhi- dro-1,4-diazino)-pirimido(5,4-d)pirimidinas
ATE37368T1 (de) Benzothiazolon-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
DE3668456D1 (de) 8-thiotetrahydrochinoleinderivate und deren salze.
ES454732A1 (es) Procedimiento de preparacion de nuevos modelos sustituidos.
SE8400629L (sv) Basiska oximetrar
DK0395527T3 (da) Imidazobenzodiazepiner og deres salte, fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og præparater med indhold deraf
ATE76398T1 (de) 4-amino-1-trifluoromethyl-tetralin-derivate, deren herstellung und deren therapeutische verwendung.
ES500108A0 (es) Procedimiento para preparar nuevas benzotiopirano (2,3-c)pi-ridinas
ES532179A0 (es) Procedimiento para preparar nuevas semicarbazidas

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

Country of ref document: DK