DK626889A - Indanderivater, deres fremstilling samt laegemidler med indhold deraf - Google Patents
Indanderivater, deres fremstilling samt laegemidler med indhold deraf Download PDFInfo
- Publication number
- DK626889A DK626889A DK626889A DK626889A DK626889A DK 626889 A DK626889 A DK 626889A DK 626889 A DK626889 A DK 626889A DK 626889 A DK626889 A DK 626889A DK 626889 A DK626889 A DK 626889A
- Authority
- DK
- Denmark
- Prior art keywords
- methyl
- preparation
- image
- indander
- medicines
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- RWRDLPDLKQPQOW-UHFFFAOYSA-N tetrahydropyrrole Natural products C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 4
- -1 methyl-(2-phenylethyl)-amino Chemical group 0.000 abstract 3
- CGFORRLIKRTSLT-UHFFFAOYSA-N 2-(3,4-dichlorophenyl)-n-methylacetamide Chemical group CNC(=O)CC1=CC=C(Cl)C(Cl)=C1 CGFORRLIKRTSLT-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- AOZUATNZXGQECR-UHFFFAOYSA-N n-methyl-2-(3-nitrophenyl)acetamide Chemical group CNC(=O)CC1=CC=CC([N+]([O-])=O)=C1 AOZUATNZXGQECR-UHFFFAOYSA-N 0.000 abstract 2
- 125000000719 pyrrolidinyl group Chemical group 0.000 abstract 2
- XKWULHLBNUUMKR-UHFFFAOYSA-N 3,5-ditert-butyl-4-hydroxy-n-methylbenzamide Chemical group CNC(=O)C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 XKWULHLBNUUMKR-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR888816605A FR2640625B2 (fr) | 1986-08-21 | 1988-12-16 | Nouveaux composes optiquement actifs derives de l'indane, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK626889D0 DK626889D0 (da) | 1989-12-12 |
| DK626889A true DK626889A (da) | 1990-06-17 |
Family
ID=9373020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK626889A DK626889A (da) | 1988-12-16 | 1989-12-12 | Indanderivater, deres fremstilling samt laegemidler med indhold deraf |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5436244A (da) |
| EP (1) | EP0374054B1 (da) |
| JP (1) | JP2753591B2 (da) |
| AT (1) | ATE95517T1 (da) |
| AU (1) | AU630136B2 (da) |
| BG (1) | BG61121B1 (da) |
| CA (1) | CA2005626A1 (da) |
| DE (1) | DE68909757T2 (da) |
| DK (1) | DK626889A (da) |
| ES (1) | ES2059805T3 (da) |
| HU (2) | HU219446B (da) |
| IE (1) | IE65151B1 (da) |
| ZA (1) | ZA899616B (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5646151A (en) * | 1996-03-08 | 1997-07-08 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
| US5763445A (en) | 1996-03-08 | 1998-06-09 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
| DE19929076A1 (de) | 1999-06-25 | 2000-12-28 | Aventis Pharma Gmbh | Indanylsubstituierte Benzolcarbonamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| KR20180017013A (ko) | 2015-05-06 | 2018-02-20 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | K-Ras 조절제 |
| GB201601301D0 (en) * | 2016-01-25 | 2016-03-09 | Takeda Pharmaceutical | Novel compounds |
| CN110785414A (zh) | 2017-04-20 | 2020-02-11 | 加利福尼亚大学董事会 | K-Ras调节剂 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1109080A (en) * | 1978-05-30 | 1981-09-15 | Hideo Kato | Indanamine derivatives |
| US4359476A (en) * | 1981-04-09 | 1982-11-16 | The Upjohn Company | Adjacently substituted cycloalkane-amide analgesics |
| GB2096607B (en) * | 1981-04-09 | 1985-02-27 | Upjohn Co | Aminocycloalkyl amides |
| US4466977A (en) * | 1981-04-09 | 1984-08-21 | The Upjohn Company | N-[2-Amino(oxy- or thia- group-substituted-cycloaliphatic)]benzeneacetamides and -benzamide analgesics |
| US4460600A (en) * | 1981-04-09 | 1984-07-17 | The Upjohn Company | Adjacently substituted ketal derivatives of cycloalkane-amide analgesics |
| US4360531A (en) * | 1981-04-09 | 1982-11-23 | The Upjohn Company | Substituted cycloalkanes |
| EP0258096B1 (fr) * | 1986-08-21 | 1992-09-09 | Roussel-Uclaf | Dérivés de l'indane, leur procédé de préparation, leur application à titre de médicaments, les compositions pharmaceutiques les renfermant et les intermédiaires obtenus |
| US4876269A (en) * | 1986-09-10 | 1989-10-24 | E. I. Du Pont De Nemours And Company | Benoz-fused cycloalkane trans-1,2-diamine derivatives |
| FR2608598B1 (fr) * | 1986-12-23 | 1989-04-14 | Roussel Uclaf | Nouveaux derives de l'indane, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions les renfermant |
-
1989
- 1989-12-12 DK DK626889A patent/DK626889A/da not_active Application Discontinuation
- 1989-12-14 JP JP1322788A patent/JP2753591B2/ja not_active Expired - Fee Related
- 1989-12-15 CA CA002005626A patent/CA2005626A1/fr not_active Abandoned
- 1989-12-15 ZA ZA899616A patent/ZA899616B/xx unknown
- 1989-12-15 IE IE402789A patent/IE65151B1/en not_active IP Right Cessation
- 1989-12-15 AT AT89403506T patent/ATE95517T1/de not_active IP Right Cessation
- 1989-12-15 HU HU631/89A patent/HU219446B/hu not_active IP Right Cessation
- 1989-12-15 EP EP89403506A patent/EP0374054B1/fr not_active Expired - Lifetime
- 1989-12-15 DE DE89403506T patent/DE68909757T2/de not_active Expired - Fee Related
- 1989-12-15 ES ES89403506T patent/ES2059805T3/es not_active Expired - Lifetime
- 1989-12-15 AU AU46802/89A patent/AU630136B2/en not_active Ceased
-
1993
- 1993-07-22 US US08/096,034 patent/US5436244A/en not_active Expired - Fee Related
-
1994
- 1994-02-23 BG BG098525A patent/BG61121B1/bg unknown
-
1995
- 1995-06-30 HU HU95P/P00668P patent/HU211609A9/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE894027L (en) | 1990-06-16 |
| JPH02218653A (ja) | 1990-08-31 |
| BG61121B2 (bg) | 1996-11-29 |
| AU630136B2 (en) | 1992-10-22 |
| JP2753591B2 (ja) | 1998-05-20 |
| DE68909757T2 (de) | 1994-03-31 |
| EP0374054A1 (fr) | 1990-06-20 |
| DE68909757D1 (de) | 1993-11-11 |
| BG61121B1 (bg) | 1996-11-29 |
| HUT53094A (en) | 1990-09-28 |
| ATE95517T1 (de) | 1993-10-15 |
| AU4680289A (en) | 1990-06-21 |
| US5436244A (en) | 1995-07-25 |
| CA2005626A1 (fr) | 1990-06-16 |
| DK626889D0 (da) | 1989-12-12 |
| IE65151B1 (en) | 1995-10-04 |
| HU211609A9 (en) | 1995-12-28 |
| ES2059805T3 (es) | 1994-11-16 |
| HU219446B (hu) | 2001-04-28 |
| ZA899616B (en) | 1991-02-27 |
| EP0374054B1 (fr) | 1993-10-06 |
| HU896631D0 (en) | 1990-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |