ES2062445T3 - Derivados de imino-2 heterociclilalquil-3 benzotiazolina, su preparacion y los medicamentos que les contienen. - Google Patents

Derivados de imino-2 heterociclilalquil-3 benzotiazolina, su preparacion y los medicamentos que les contienen.

Info

Publication number
ES2062445T3
ES2062445T3 ES90401976T ES90401976T ES2062445T3 ES 2062445 T3 ES2062445 T3 ES 2062445T3 ES 90401976 T ES90401976 T ES 90401976T ES 90401976 T ES90401976 T ES 90401976T ES 2062445 T3 ES2062445 T3 ES 2062445T3
Authority
ES
Spain
Prior art keywords
preparation
heterociclilalquil
benzotiazolina
imino
medicines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90401976T
Other languages
English (en)
Inventor
Patrick Jimonet
Blevec Joseph Le
Conception Nemecek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8909483A external-priority patent/FR2649704B1/fr
Priority claimed from FR9005889A external-priority patent/FR2661910B1/fr
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Application granted granted Critical
Publication of ES2062445T3 publication Critical patent/ES2062445T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)

Abstract

COMPUESTOS DE FORMULA: (FIG. A), EN LA QUE R1 ES UN RADICAL PIPERAZINIL-1 SUSTITUIDO, TETRAHIDRO-1,2,3,6 PIRIDINIL-1 SUSTITUIDO O PIPERIDINO SUSTITUIDO; R2 ES UN RADICAL POLIFLUOROALCOXI; Y N ES IGUAL A 2 O 3, LAS SALES DE ESTOS COMPUESTOS CON UN ACIDO, LOS PROCEDIMIENTOS PARA SU OBTENCION Y LOS MEDICAMENTOS QUE LOS CONTIENEN.
ES90401976T 1989-07-13 1990-07-09 Derivados de imino-2 heterociclilalquil-3 benzotiazolina, su preparacion y los medicamentos que les contienen. Expired - Lifetime ES2062445T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8909483A FR2649704B1 (fr) 1989-07-13 1989-07-13 Derives d'imino-2 ethyl-3 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
FR9005889A FR2661910B1 (fr) 1990-05-11 1990-05-11 Derives d'imino-2 heterocyclylalkyl-3 benzothiazoline, leur preparation et les medicaments les contenant.

Publications (1)

Publication Number Publication Date
ES2062445T3 true ES2062445T3 (es) 1994-12-16

Family

ID=26227474

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90401976T Expired - Lifetime ES2062445T3 (es) 1989-07-13 1990-07-09 Derivados de imino-2 heterociclilalquil-3 benzotiazolina, su preparacion y los medicamentos que les contienen.

Country Status (20)

Country Link
EP (1) EP0409692B1 (es)
JP (1) JPH0386871A (es)
AT (1) ATE102612T1 (es)
AU (1) AU624972B2 (es)
CA (1) CA2021031A1 (es)
CZ (1) CZ281164B6 (es)
DE (1) DE69007196T2 (es)
DK (1) DK0409692T3 (es)
ES (1) ES2062445T3 (es)
FI (1) FI93109C (es)
HU (1) HU210827B (es)
IE (1) IE63318B1 (es)
IL (1) IL95053A (es)
NO (1) NO175590C (es)
NZ (1) NZ234487A (es)
PL (2) PL164326B1 (es)
PT (1) PT94701B (es)
RU (1) RU1836368C (es)
SK (1) SK278908B6 (es)
YU (1) YU47723B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2674853B1 (fr) * 1991-04-03 1995-01-20 Synthelabo Derives de piperidinylguanidine, leur preparation et leur application en therapeutique.
FR2678619B1 (fr) * 1991-07-04 1993-09-17 Rhone Poulenc Rorer Sa Derives de 1,2,4-thiadiazolo[3,4-b]benzothiazole, leur preparation et les medicaments les contenant.
AU3957093A (en) * 1992-04-15 1993-11-18 Rhone-Poulenc Rorer S.A. 3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxide-3-carboxyl ic acid derivatives, preparation thereof and drugs containing same
FR2696457B1 (fr) * 1992-10-02 1994-11-25 Rhone Poulenc Rorer Sa Dérivés de 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxyde, leur préparation et les médicaments les contenant.
US5889010A (en) * 1995-05-18 1999-03-30 Pfizer Inc. Benzimidazole derivatives having dopaminergic activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2631163B2 (de) * 1976-07-10 1978-06-29 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 2-Iminobenzothiazolen
FR2492258A1 (fr) * 1980-10-17 1982-04-23 Pharmindustrie Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole
US4980356A (en) * 1988-12-15 1990-12-25 Rhone-Poulenc Sante 2-imino-6-polyfluoroalkoxybenzothiazole derivatives, and pharamaceutical compositions containing them and their treatment of medical conditions associated with the effects of glutamate
FR2649701B2 (fr) * 1988-12-15 1991-11-22 Rhone Poulenc Sante Derives d'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant

Also Published As

Publication number Publication date
SK342590A3 (en) 1998-04-08
AU624972B2 (en) 1992-06-25
NO903113L (no) 1991-01-14
CZ281164B6 (cs) 1996-07-17
PT94701A (pt) 1991-03-20
PL164152B1 (pl) 1994-06-30
NO903113D0 (no) 1990-07-12
RU1836368C (ru) 1993-08-23
PT94701B (pt) 1997-03-31
FI93109B (fi) 1994-11-15
EP0409692A3 (en) 1991-03-27
IL95053A (en) 1994-05-30
CA2021031A1 (fr) 1991-01-14
EP0409692A2 (fr) 1991-01-23
JPH0386871A (ja) 1991-04-11
IL95053A0 (en) 1991-06-10
PL164326B1 (pl) 1994-07-29
HU904189D0 (en) 1990-12-28
IE63318B1 (en) 1995-04-05
DE69007196T2 (de) 1994-06-30
DE69007196D1 (de) 1994-04-14
DK0409692T3 (da) 1994-04-05
FI93109C (fi) 1995-02-27
FI903531A0 (fi) 1990-07-12
IE902551A1 (en) 1991-02-27
AU5884790A (en) 1991-01-17
NO175590C (no) 1994-11-02
YU133990A (sh) 1992-07-20
CZ342590A3 (en) 1996-01-17
EP0409692B1 (fr) 1994-03-09
ATE102612T1 (de) 1994-03-15
NO175590B (no) 1994-07-25
NZ234487A (en) 1992-04-28
YU47723B (sh) 1996-01-08
SK278908B6 (sk) 1998-04-08
HUT58732A (en) 1992-03-30
HU210827B (en) 1995-08-28

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