DE69007196D1 - 2-Imino-3 heterocyclylamino-benzothiazoline, ihre Herstellung und sie enthaltende Arzneimittel. - Google Patents

2-Imino-3 heterocyclylamino-benzothiazoline, ihre Herstellung und sie enthaltende Arzneimittel.

Info

Publication number
DE69007196D1
DE69007196D1 DE90401976T DE69007196T DE69007196D1 DE 69007196 D1 DE69007196 D1 DE 69007196D1 DE 90401976 T DE90401976 T DE 90401976T DE 69007196 T DE69007196 T DE 69007196T DE 69007196 D1 DE69007196 D1 DE 69007196D1
Authority
DE
Germany
Prior art keywords
preparation
benzothiazolines
heterocyclylamino
imino
medicaments containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90401976T
Other languages
English (en)
Other versions
DE69007196T2 (de
Inventor
Patrick Jimonet
Blevec Joseph Le
Conception Nemecek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8909483A external-priority patent/FR2649704B1/fr
Priority claimed from FR9005889A external-priority patent/FR2661910B1/fr
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Publication of DE69007196D1 publication Critical patent/DE69007196D1/de
Application granted granted Critical
Publication of DE69007196T2 publication Critical patent/DE69007196T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE69007196T 1989-07-13 1990-07-09 2-Imino-3 heterocyclylamino-benzothiazoline, ihre Herstellung und sie enthaltende Arzneimittel. Expired - Fee Related DE69007196T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8909483A FR2649704B1 (fr) 1989-07-13 1989-07-13 Derives d'imino-2 ethyl-3 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
FR9005889A FR2661910B1 (fr) 1990-05-11 1990-05-11 Derives d'imino-2 heterocyclylalkyl-3 benzothiazoline, leur preparation et les medicaments les contenant.

Publications (2)

Publication Number Publication Date
DE69007196D1 true DE69007196D1 (de) 1994-04-14
DE69007196T2 DE69007196T2 (de) 1994-06-30

Family

ID=26227474

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69007196T Expired - Fee Related DE69007196T2 (de) 1989-07-13 1990-07-09 2-Imino-3 heterocyclylamino-benzothiazoline, ihre Herstellung und sie enthaltende Arzneimittel.

Country Status (20)

Country Link
EP (1) EP0409692B1 (de)
JP (1) JPH0386871A (de)
AT (1) ATE102612T1 (de)
AU (1) AU624972B2 (de)
CA (1) CA2021031A1 (de)
CZ (1) CZ281164B6 (de)
DE (1) DE69007196T2 (de)
DK (1) DK0409692T3 (de)
ES (1) ES2062445T3 (de)
FI (1) FI93109C (de)
HU (1) HU210827B (de)
IE (1) IE63318B1 (de)
IL (1) IL95053A (de)
NO (1) NO175590C (de)
NZ (1) NZ234487A (de)
PL (2) PL164152B1 (de)
PT (1) PT94701B (de)
RU (1) RU1836368C (de)
SK (1) SK278908B6 (de)
YU (1) YU47723B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2674853B1 (fr) * 1991-04-03 1995-01-20 Synthelabo Derives de piperidinylguanidine, leur preparation et leur application en therapeutique.
FR2678619B1 (fr) * 1991-07-04 1993-09-17 Rhone Poulenc Rorer Sa Derives de 1,2,4-thiadiazolo[3,4-b]benzothiazole, leur preparation et les medicaments les contenant.
FR2696457B1 (fr) * 1992-10-02 1994-11-25 Rhone Poulenc Rorer Sa Dérivés de 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxyde, leur préparation et les médicaments les contenant.
AU3957093A (en) * 1992-04-15 1993-11-18 Rhone-Poulenc Rorer S.A. 3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxide-3-carboxyl ic acid derivatives, preparation thereof and drugs containing same
US5889010A (en) * 1995-05-18 1999-03-30 Pfizer Inc. Benzimidazole derivatives having dopaminergic activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2631163B2 (de) * 1976-07-10 1978-06-29 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 2-Iminobenzothiazolen
FR2492258A1 (fr) * 1980-10-17 1982-04-23 Pharmindustrie Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole
FR2649701B2 (fr) * 1988-12-15 1991-11-22 Rhone Poulenc Sante Derives d'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
US4980356A (en) * 1988-12-15 1990-12-25 Rhone-Poulenc Sante 2-imino-6-polyfluoroalkoxybenzothiazole derivatives, and pharamaceutical compositions containing them and their treatment of medical conditions associated with the effects of glutamate

Also Published As

Publication number Publication date
EP0409692A3 (en) 1991-03-27
AU5884790A (en) 1991-01-17
CZ281164B6 (cs) 1996-07-17
YU133990A (sh) 1992-07-20
NO903113D0 (no) 1990-07-12
IL95053A (en) 1994-05-30
JPH0386871A (ja) 1991-04-11
PL164152B1 (pl) 1994-06-30
DK0409692T3 (da) 1994-04-05
FI93109B (fi) 1994-11-15
NZ234487A (en) 1992-04-28
IL95053A0 (en) 1991-06-10
SK342590A3 (en) 1998-04-08
SK278908B6 (sk) 1998-04-08
EP0409692A2 (de) 1991-01-23
ES2062445T3 (es) 1994-12-16
ATE102612T1 (de) 1994-03-15
IE902551A1 (en) 1991-02-27
EP0409692B1 (de) 1994-03-09
FI93109C (fi) 1995-02-27
RU1836368C (ru) 1993-08-23
PT94701B (pt) 1997-03-31
PT94701A (pt) 1991-03-20
PL164326B1 (pl) 1994-07-29
HU210827B (en) 1995-08-28
DE69007196T2 (de) 1994-06-30
HUT58732A (en) 1992-03-30
CA2021031A1 (fr) 1991-01-14
NO175590C (no) 1994-11-02
NO903113L (no) 1991-01-14
AU624972B2 (en) 1992-06-25
NO175590B (no) 1994-07-25
CZ342590A3 (en) 1996-01-17
IE63318B1 (en) 1995-04-05
YU47723B (sh) 1996-01-08
HU904189D0 (en) 1990-12-28
FI903531A0 (fi) 1990-07-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee