ES454732A1 - Procedimiento de preparacion de nuevos modelos sustituidos. - Google Patents
Procedimiento de preparacion de nuevos modelos sustituidos.Info
- Publication number
- ES454732A1 ES454732A1 ES454732A ES454732A ES454732A1 ES 454732 A1 ES454732 A1 ES 454732A1 ES 454732 A ES454732 A ES 454732A ES 454732 A ES454732 A ES 454732A ES 454732 A1 ES454732 A1 ES 454732A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- alkyl
- group
- alkoxy
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
Procedimiento de preparación de nuevos indoles sustituidos de fórmula I: **(Fórmula)** en la que R1 representa un átomo de hidrógeno, un átomo de halógeno, un radical trifluorometilo, un radical alcohilo que contiene de 1 a 8 átomos de carbono o un radical alcoxi que contiene de 1 a 8 átomos de carbono; R2 en la posición 2, 3 ó 4, representan un átomo de halógeno, un radical trifluorometilo, un radical alcohilo que contiene de 1 a 8 átomos de carbono, un radical alcoxi que contiene de 1 a 8 átomos de carbono o un radical alcohiltio que contiene de 1 a 8 átomos de carbono; A representa bien un radical alcohilo lineal de fórmula (CH2)n, representando n un número entero que puede variar de 2 a 5, o bien un radical alcohilo ramificado que contiene de 3 a 5 átomos de carbono.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7601560A FR2338702A1 (fr) | 1976-01-21 | 1976-01-21 | Nouveaux indoles substitues, leur procede de preparation et leur application comme medicament |
FR7629652A FR2366016A2 (fr) | 1976-10-01 | 1976-10-01 | Nouveaux indoles substitues, leur procede de preparation et leur application comme medicament |
Publications (1)
Publication Number | Publication Date |
---|---|
ES454732A1 true ES454732A1 (es) | 1978-03-16 |
Family
ID=26219260
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES454732A Expired ES454732A1 (es) | 1976-01-21 | 1976-12-31 | Procedimiento de preparacion de nuevos modelos sustituidos. |
Country Status (19)
Country | Link |
---|---|
US (1) | US4105777A (es) |
JP (1) | JPS5291858A (es) |
AR (1) | AR216755A1 (es) |
AT (1) | AT357517B (es) |
AU (2) | AU512091B1 (es) |
CA (1) | CA1091233A (es) |
CH (1) | CH599154A5 (es) |
DE (1) | DE2701095A1 (es) |
DK (1) | DK20977A (es) |
ES (1) | ES454732A1 (es) |
GB (1) | GB1523703A (es) |
GR (1) | GR61775B (es) |
HU (1) | HU175413B (es) |
IE (1) | IE44337B1 (es) |
IL (1) | IL51217A (es) |
LU (1) | LU76612A1 (es) |
NL (1) | NL7700667A (es) |
PT (1) | PT66094B (es) |
SE (1) | SE421917B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4885295A (en) * | 1984-08-06 | 1989-12-05 | Sterling Drug Inc. | Method of use of 3-arylcarbonyl- and 3-cycloalkyl-carbonyl-1-aminoalkyl-1H-indoles |
WO2007022501A2 (en) * | 2005-08-18 | 2007-02-22 | Microbia, Inc. | Useful indole compounds |
EP1998766A2 (en) * | 2005-12-16 | 2008-12-10 | Ironwood Pharmaceuticals, Inc. | Useful indole compounds |
JP5406716B2 (ja) | 2006-08-07 | 2014-02-05 | アイアンウッド ファーマシューティカルズ インコーポレイテッド | インドール化合物 |
US8937265B2 (en) * | 2007-02-27 | 2015-01-20 | Illinois Tool Works, Inc. | Welding-type system having a wire feeder system having integrated power source controls and a welding-type power source that is free power parameter selection interfaces |
AR084433A1 (es) | 2010-12-22 | 2013-05-15 | Ironwood Pharmaceuticals Inc | Inhibidores de la faah y composiciones farmaceuticas que los contienen |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB888535A (en) * | 1959-01-05 | 1962-01-31 | Lepetit Spa | Indole compounds |
US3047584A (en) * | 1960-04-27 | 1962-07-31 | Elkin Samuel | Indole-carboxylic acid-dialkylamino alkyl esters |
US3557142A (en) * | 1968-02-20 | 1971-01-19 | Sterling Drug Inc | 4,5,6,7-tetrahydro-indole-lower-alkanoic acids and esters |
-
1976
- 1976-12-13 SE SE7613991A patent/SE421917B/xx unknown
- 1976-12-31 ES ES454732A patent/ES454732A1/es not_active Expired
-
1977
- 1977-01-05 AR AR266109A patent/AR216755A1/es active
- 1977-01-06 IL IL51217A patent/IL51217A/xx unknown
- 1977-01-07 HU HU77RO908A patent/HU175413B/hu unknown
- 1977-01-12 US US05/758,633 patent/US4105777A/en not_active Expired - Lifetime
- 1977-01-12 DE DE19772701095 patent/DE2701095A1/de not_active Withdrawn
- 1977-01-18 AT AT26077A patent/AT357517B/de not_active IP Right Cessation
- 1977-01-20 PT PT66094A patent/PT66094B/pt unknown
- 1977-01-20 GR GR52611A patent/GR61775B/el unknown
- 1977-01-20 AU AU21489/77A patent/AU512091B1/en not_active Expired
- 1977-01-20 LU LU76612A patent/LU76612A1/xx unknown
- 1977-01-20 IE IE117/77A patent/IE44337B1/en unknown
- 1977-01-20 GB GB2379/77A patent/GB1523703A/en not_active Expired
- 1977-01-20 AU AU21489/77D patent/AU2148977A/en not_active Expired
- 1977-01-20 CA CA270,138A patent/CA1091233A/fr not_active Expired
- 1977-01-20 DK DK20977A patent/DK20977A/da not_active Application Discontinuation
- 1977-01-21 NL NL7700667A patent/NL7700667A/xx not_active Application Discontinuation
- 1977-01-21 JP JP504777A patent/JPS5291858A/ja active Pending
- 1977-01-21 CH CH78677A patent/CH599154A5/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AR216755A1 (es) | 1980-01-31 |
CH599154A5 (es) | 1978-05-12 |
IL51217A (en) | 1980-07-31 |
LU76612A1 (es) | 1977-07-27 |
PT66094A (fr) | 1977-02-01 |
GR61775B (en) | 1979-01-16 |
AU512091B1 (en) | 1980-09-25 |
ATA26077A (de) | 1979-12-15 |
JPS5291858A (en) | 1977-08-02 |
NL7700667A (nl) | 1977-07-25 |
SE7613991L (sv) | 1977-07-22 |
AT357517B (de) | 1980-07-10 |
IE44337L (en) | 1977-07-21 |
IE44337B1 (en) | 1981-10-21 |
PT66094B (fr) | 1978-12-12 |
HU175413B (hu) | 1980-07-28 |
IL51217A0 (en) | 1977-03-31 |
DE2701095A1 (de) | 1977-07-28 |
SE421917B (sv) | 1982-02-08 |
GB1523703A (en) | 1978-09-06 |
CA1091233A (fr) | 1980-12-09 |
AU2148977A (en) | 1978-07-27 |
US4105777A (en) | 1978-08-08 |
DK20977A (da) | 1977-07-22 |
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