ES8405372A1 - Un procedimiento para preparar un enantiomero puro de un fenilazacicloalcano sustituido. - Google Patents

Un procedimiento para preparar un enantiomero puro de un fenilazacicloalcano sustituido.

Info

Publication number
ES8405372A1
ES8405372A1 ES521080A ES521080A ES8405372A1 ES 8405372 A1 ES8405372 A1 ES 8405372A1 ES 521080 A ES521080 A ES 521080A ES 521080 A ES521080 A ES 521080A ES 8405372 A1 ES8405372 A1 ES 8405372A1
Authority
ES
Spain
Prior art keywords
group
carbon atoms
alkyl group
hydrogen
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES521080A
Other languages
English (en)
Other versions
ES521080A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra Lakemedel AB
Original Assignee
Astra Lakemedel AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Lakemedel AB filed Critical Astra Lakemedel AB
Publication of ES8405372A1 publication Critical patent/ES8405372A1/es
Publication of ES521080A0 publication Critical patent/ES521080A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN ENANTIOMERO PURO DE UN FENILAZACICLOALCANO SUSTITUIDO.CONSISTE EN ESCINDIR UN ENANTIOMERO PURO DE UN ETER O ESTER DE FORMULA (II) PARA FORMAR EL COMPUESTO DE FORMULA GENERAL (I), DONDE Y ES -OH, RCOO, R R NCOO- O RO; R ES UN RESTO DE HIDROCARBURO ALIFATICO CON C 1 A 17, UN GRUPO FENILO Y OTROS; R ES HIDROGENO, GRUPO ALCOHILO CON C 1 A 5, GRUPO FENETILO, BENCILO O FENILO MONO- O DISUSTITUIDO POR GRUPOS METILO, METOXI, HIDROXI, NITRO O CIANO; R ES H, ALCOHILO CON C 1 A 5, FENILO Y OTROS; Y R ES UN GRUPO ALILO O BENCILO. POSTERIORMENTELA BASE OBTENIDA SE CONVIERTE EN UNA SAL DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLE.TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD TERAPEUTICA EN EL SISTEMA NERVIOSO CENTRAL.
ES521080A 1982-03-30 1983-03-29 Un procedimiento para preparar un enantiomero puro de un fenilazacicloalcano sustituido. Granted ES521080A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8202023A SE446335B (sv) 1982-03-30 1982-03-30 Ren enantiomer av en metasubstituerad 3-fenyl-1-propylpiperidin

Publications (2)

Publication Number Publication Date
ES8405372A1 true ES8405372A1 (es) 1984-06-01
ES521080A0 ES521080A0 (es) 1984-06-01

Family

ID=20346417

Family Applications (3)

Application Number Title Priority Date Filing Date
ES521080A Granted ES521080A0 (es) 1982-03-30 1983-03-29 Un procedimiento para preparar un enantiomero puro de un fenilazacicloalcano sustituido.
ES530186A Expired ES8602655A1 (es) 1982-03-30 1984-03-01 Un procedimiento para preparar un enantiomero puro de un fenilazacicloalcano sustituido
ES539031A Granted ES539031A0 (es) 1982-03-30 1984-12-24 Un procedimiento para preparar un enantiomero puro de un fenilazacicloalcano sustituido

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES530186A Expired ES8602655A1 (es) 1982-03-30 1984-03-01 Un procedimiento para preparar un enantiomero puro de un fenilazacicloalcano sustituido
ES539031A Granted ES539031A0 (es) 1982-03-30 1984-12-24 Un procedimiento para preparar un enantiomero puro de un fenilazacicloalcano sustituido

Country Status (17)

Country Link
EP (1) EP0097628B1 (es)
JP (1) JPS58177971A (es)
AT (1) ATE56705T1 (es)
AU (1) AU564287B2 (es)
CA (1) CA1202307A (es)
DD (1) DD209621A5 (es)
DE (1) DE3381885D1 (es)
DK (1) DK162214C (es)
ES (3) ES521080A0 (es)
FI (1) FI81088C (es)
GB (1) GB2117771B (es)
GR (1) GR79244B (es)
HU (1) HU191290B (es)
IE (1) IE55261B1 (es)
NO (1) NO164024C (es)
PT (1) PT76481B (es)
SE (1) SE446335B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8305362D0 (sv) * 1983-09-30 1983-09-30 Astra Laekemedel Ab Novel substituted phenylazacycloalkanes, processes for preparation and pharmaceutical preparations for such compounds
SE9904724D0 (sv) * 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission I
JP2011057619A (ja) * 2009-09-10 2011-03-24 Tokai Univ 光学活性アミン化合物の製造方法、並びに、ジアステレオマー塩及びその製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3070247D1 (en) * 1979-12-05 1985-04-04 Astra Laekemedel Ab New phenyl-azacycloalkanes, processes for preparation and pharmaceutical preparations for such compounds

Also Published As

Publication number Publication date
FI81088B (fi) 1990-05-31
ATE56705T1 (de) 1990-10-15
DK162214B (da) 1991-09-30
GR79244B (es) 1984-10-22
SE446335B (sv) 1986-09-01
ES8601889A1 (es) 1985-11-16
NO164024C (no) 1990-08-22
ES539031A0 (es) 1985-11-16
NO164024B (no) 1990-05-14
IE830685L (en) 1983-09-30
HU191290B (en) 1987-02-27
GB8308657D0 (en) 1983-05-05
GB2117771B (en) 1985-12-04
AU564287B2 (en) 1987-08-06
EP0097628A3 (en) 1984-07-18
GB2117771A (en) 1983-10-19
DK143483A (da) 1983-10-01
DK162214C (da) 1992-03-16
EP0097628B1 (en) 1990-09-19
PT76481A (en) 1983-04-01
PT76481B (en) 1986-02-27
ES530186A0 (es) 1985-12-01
IE55261B1 (en) 1990-07-18
AU1284583A (en) 1983-10-06
FI831068L (fi) 1983-10-01
DE3381885D1 (de) 1990-10-25
JPS6155906B2 (es) 1986-11-29
EP0097628A2 (en) 1984-01-04
CA1202307A (en) 1986-03-25
FI81088C (fi) 1990-09-10
ES521080A0 (es) 1984-06-01
FI831068A0 (fi) 1983-03-29
DD209621A5 (de) 1984-05-16
DK143483D0 (da) 1983-03-29
ES8602655A1 (es) 1985-12-01
JPS58177971A (ja) 1983-10-18
SE8202023L (sv) 1983-10-01
NO831040L (no) 1983-10-03

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20041102