ZA863399B - Method of preparing an extemporaneous homogenous microcapsule suspension - Google Patents

Method of preparing an extemporaneous homogenous microcapsule suspension

Info

Publication number
ZA863399B
ZA863399B ZA863399A ZA863399A ZA863399B ZA 863399 B ZA863399 B ZA 863399B ZA 863399 A ZA863399 A ZA 863399A ZA 863399 A ZA863399 A ZA 863399A ZA 863399 B ZA863399 B ZA 863399B
Authority
ZA
South Africa
Prior art keywords
extemporaneous
homogenous
preparing
microcapsule suspension
prepare
Prior art date
Application number
ZA863399A
Other languages
English (en)
Inventor
Massimo Calanchi
Leonardo Gentilini
Marco Marconi
Original Assignee
Eurand Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand Spa filed Critical Eurand Spa
Publication of ZA863399B publication Critical patent/ZA863399B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA863399A 1985-05-08 1986-05-07 Method of preparing an extemporaneous homogenous microcapsule suspension ZA863399B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20617/85A IT1183574B (it) 1985-05-08 1985-05-08 Metodo per ottenere una sospensione estemporanea omogenea di microcapsule

Publications (1)

Publication Number Publication Date
ZA863399B true ZA863399B (en) 1987-01-28

Family

ID=11169617

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA863399A ZA863399B (en) 1985-05-08 1986-05-07 Method of preparing an extemporaneous homogenous microcapsule suspension

Country Status (19)

Country Link
US (1) US5008117A (xx)
EP (1) EP0222856B1 (xx)
JP (1) JP2609597B2 (xx)
KR (1) KR900000212B1 (xx)
AT (1) ATE59287T1 (xx)
AU (1) AU589644B2 (xx)
CA (1) CA1274144A (xx)
DE (1) DE3676642D1 (xx)
DK (1) DK157730C (xx)
ES (1) ES8707103A1 (xx)
FI (1) FI86596C (xx)
HU (1) HUT44168A (xx)
IT (1) IT1183574B (xx)
NO (1) NO171949C (xx)
NZ (1) NZ216062A (xx)
PT (1) PT82541B (xx)
RU (1) RU2059409C1 (xx)
WO (1) WO1986006626A1 (xx)
ZA (1) ZA863399B (xx)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
GB8702411D0 (en) * 1987-02-03 1987-03-11 Zyma Sa Swellable pellets
AU618096B2 (en) * 1988-04-19 1991-12-12 Southwest Research Institute Controlled release of active ingredients from capsules having a salt sensitive shell material
US5064650A (en) * 1988-04-19 1991-11-12 Southwest Research Institute Controlled-release salt sensitive capsule for oral use and adhesive system
FR2634376B1 (fr) * 1988-07-21 1992-04-17 Farmalyoc Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation
NZ234143A (en) * 1989-06-28 1991-10-25 Mcneil Ppc Inc Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents
US5112604A (en) * 1989-09-01 1992-05-12 Riker Laboratories, Inc. Oral suspension formulation
IT1246350B (it) * 1990-07-11 1994-11-17 Eurand Int Metodo per ottenere una rapida sospensione in acqua di farmaci insolubili
US5300302A (en) * 1990-10-04 1994-04-05 Nestec S.A. Pharmaceutical composition in gel form in a dispensing package
US5252337A (en) * 1991-06-25 1993-10-12 Eurand America, Inc. Controlled release calcium channel blocker microcapsules
US5599556A (en) * 1991-12-31 1997-02-04 Abbott Laboratories Prolamine coatings for taste masking
US5272137A (en) * 1992-02-14 1993-12-21 Mcneil-Pfc, Inc. Aqueous pharmaceutical suspension for pharmaceutical actives
ZA932273B (en) * 1992-03-30 1993-11-26 Alza Corp Additives for bioerodible polymers to regulate degradation
US5540912A (en) * 1992-03-30 1996-07-30 Alza Corporation Viscous suspensions of controlled-release drug particles
HU215958B (hu) * 1992-04-30 1999-03-29 Schering Corp. Eljárás stabil, hidratált, száraz ceftibuten porkészítmény előállítására perorális szuszpenziókhoz
US5422122A (en) * 1992-08-04 1995-06-06 Eurand America, Incorporated Controlled release potassium chloride tablet
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
EP0620001A1 (en) * 1993-04-16 1994-10-19 McNEIL-PPC, INC. Aqueous pharmaceutical suspension and process for preparation thereof
GB2318511A (en) * 1996-10-23 1998-04-29 Eurand Int Process for the preparation of a pharmaceutical composition for rapid suspension in water
UA65607C2 (uk) 1998-03-04 2004-04-15 Орто-Макнейл Фармацевтикал, Інк. Фармацевтична композиція (варіанти) та спосіб її приготування
GB9822170D0 (en) * 1998-10-13 1998-12-02 Danbioyst Uk Ltd Novel formulations of fexofenadine
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6159491A (en) * 1999-02-12 2000-12-12 Biovector Technologies, Inc. Prolonged release bioadhesive vaginal gel dosage form
US6500462B1 (en) * 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
US6932861B2 (en) 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
AU2002225763A1 (en) 2000-11-28 2002-06-11 Fmc Corporation Edible pga(propylene glycol alginate) coating composition
KR20040025880A (ko) * 2000-12-11 2004-03-26 다케다 야쿠힌 고교 가부시키가이샤 수용해성이 개선된 의약 조성물
JP2004168703A (ja) * 2002-11-20 2004-06-17 Shin Etsu Chem Co Ltd マイクロカプセル及びその製造方法
US20040170686A1 (en) * 2003-01-31 2004-09-02 Fredrickson Jennifer K. Suspension vehicle for coated drug particles
US20040191326A1 (en) * 2003-03-31 2004-09-30 Reo Joseph P. Taste-masking vehicle for coated oxazolidinone particles
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
US20050118194A1 (en) * 2003-12-01 2005-06-02 Sin Yoke M. Oral vaccine, method for its preparation and use thereof
US20060134210A1 (en) * 2004-12-22 2006-06-22 Astrazeneca Ab Solid dosage form comprising proton pump inhibitor and suspension made thereof
WO2018130876A1 (en) * 2017-01-10 2018-07-19 Dukebox Sp. Z O. O. A method of manufacturing a suspension of nanoparticles of potassium salt or magnesium salt
CN113490486A (zh) 2019-02-22 2021-10-08 康特伦英国斯温顿捷迪斯有限公司 最小化团聚、曝气和保持包含布洛芬的药物组合物的包衣
BR112021016408A2 (pt) * 2019-02-22 2021-10-13 Catalent U.K. Swindon Zydis Limited Minimização de aeração de suspensões durante mistura em linha
MX2021009845A (es) 2019-02-22 2021-09-10 Catalent Uk Swindon Zydis Ltd Minimizacion de la aglomeracion de material de revestimiento de particula de medicamento durante el almacenaje para estabilizar los tiempos de desintegracion de productos farmaceuticos.
RU2731599C1 (ru) * 2019-07-17 2020-09-04 Общество с ограниченной ответственностью "РУСИНТЕХ" Способ получения микрокапсулированного термоактивируемого огнегасящего агента

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB844772A (en) * 1956-04-19 1960-08-17 Pfizer & Co C Granular pharmaceutical compositions and process for preparing same
FR2077696B1 (xx) * 1970-02-06 1973-03-16 Synthelabo
DE2211019C3 (de) * 1972-03-08 1980-08-28 Bayer Ag, 5090 Leverkusen Geschmacksverbessernde Formulierungen oraler Penicilline
US4155741A (en) * 1974-05-01 1979-05-22 Stauffer Chemical Company Stable suspension system for microencapsulated flowable formulations, and method of preparing stable suspension of microcapsules
US4126672A (en) * 1976-02-04 1978-11-21 Hoffmann-La Roche Inc. Sustained release pharmaceutical capsules
US4189499A (en) * 1977-03-16 1980-02-19 Biochefarm S.A. Lysine 4-allyloxy-3-chlorophenylacetate and method of its preparation
IT1148784B (it) * 1980-04-09 1986-12-03 Eurand Spa Procedimento per la preparazione di microcapsule in un veicolo liquido
IT1209276B (it) * 1980-11-05 1989-07-16 Magis Farmaceutici Composizione farmaceutica per la somministrazione orale del metilestere dell'acido 13a-etil-2,3,5,6,12,13,13a,13b-ottaidro-12-idrossi1h-indolo-[3,2,1-de] pirido [3,2,1-ij] [1,5] naftiridina -12-carbossilico

Also Published As

Publication number Publication date
AU589644B2 (en) 1989-10-19
KR900000212B1 (ko) 1990-01-23
ATE59287T1 (de) 1991-01-15
FI86596C (fi) 1992-09-25
EP0222856A1 (en) 1987-05-27
FI86596B (fi) 1992-06-15
RU2059409C1 (ru) 1996-05-10
US5008117A (en) 1991-04-16
NO865162L (no) 1986-12-18
EP0222856B1 (en) 1990-12-27
AU5903186A (en) 1986-12-04
DK7487A (da) 1987-01-07
FI865336A (fi) 1986-12-30
IT1183574B (it) 1987-10-22
HUT44168A (en) 1988-02-29
FI865336A0 (fi) 1986-12-30
WO1986006626A1 (en) 1986-11-20
IT8520617A0 (it) 1985-05-08
NZ216062A (en) 1989-07-27
NO171949C (no) 1993-05-26
ES554777A0 (es) 1987-07-16
PT82541A (en) 1986-06-01
PT82541B (pt) 1988-03-03
DK7487D0 (da) 1987-01-07
KR870700209A (ko) 1987-05-30
JP2609597B2 (ja) 1997-05-14
JPS62502859A (ja) 1987-11-12
NO171949B (no) 1993-02-15
ES8707103A1 (es) 1987-07-16
DK157730C (da) 1990-07-16
DK157730B (da) 1990-02-12
DE3676642D1 (de) 1991-02-07
CA1274144A (en) 1990-09-18

Similar Documents

Publication Publication Date Title
ZA863399B (en) Method of preparing an extemporaneous homogenous microcapsule suspension
DK158718C (da) Fremgangsmaade til flokkulation af suspenderede faste stoffer i en vandig suspension
FR2621592B1 (fr) Procede de preparation d'une dispersion aqueuse contenant des particules de polymere
IL82642A0 (en) Aqueous suspension concentrate composition of pendimethalin
NO881625D0 (no) Fremgangsmaate for fremstilling av stabile sucralfatsuspensjoner.
ES2054052T3 (es) Procedimiento de preparacion de sistemas coloidales dispersables de una proteina en forma de nanoparticulas.
FR2632524B1 (fr) Procede de preparation d'une fraction concentree en facteur viia et son application a titre de medicament
ATE64924T1 (de) Verfahren zur herstellung von 3-methyl-1-vinylimidazoliumchloriden und ihre verwendung zur herstellung von polymerisaten.
DE3373492D1 (en) Stable concentrated aqueous dispersions of water-insoluble cationic compounds and preparation thereof
FI864439A (fi) Karboksyyliryhmiä sisältävät polyamidit, menetelmä niiden valmistamiseksi ja niiden käyttö vesipitoisten pronssidispersioiden valmistamiseksi
JPS57207589A (en) Flocculating method for protein existing in solution or suspension state
DK0957065T3 (da) Aluminiumsilicat-suspension
TR23766A (tr) Bir hetero polisakkaritin sulu coezeltisini hazir- lamak icin yoentem
FR2657010B1 (fr) Composition pharmaceutique sous forme de suspension aqueuse stable a base de sucrafalte et d'une substance anti-acide ainsi que son procede de preparation.
SU1658587A1 (ru) Способ приготовления огнеупорного раствора
EG18376A (en) Aqueous suspension concentrate of pendimethalin
KR840002018A (ko) 입자상 고체물질의 수성현탁액 제조방법
BR8706237A (pt) Sistema de encaixe empregado na formacao de valores e suas diversificacoes construtivas
TH6788EX (th) แชมพูชนิดพีเอชต่ำที่มีคลิมบาโซลอยู่ด้วย
RU92016552A (ru) Очистка водной жидкости