HUT44168A - Process for production of composition assuring eventual homogene suspension of particles containing active substance - Google Patents

Process for production of composition assuring eventual homogene suspension of particles containing active substance

Info

Publication number
HUT44168A
HUT44168A HU863345A HU334586A HUT44168A HU T44168 A HUT44168 A HU T44168A HU 863345 A HU863345 A HU 863345A HU 334586 A HU334586 A HU 334586A HU T44168 A HUT44168 A HU T44168A
Authority
HU
Hungary
Prior art keywords
eventual
production
active substance
particles containing
containing active
Prior art date
Application number
HU863345A
Other languages
English (en)
Inventor
Massimo Calanchi
Leonardo Gentili
Marco Marconi
Original Assignee
Eurand Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand Spa filed Critical Eurand Spa
Publication of HUT44168A publication Critical patent/HUT44168A/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HU863345A 1985-05-08 1986-05-02 Process for production of composition assuring eventual homogene suspension of particles containing active substance HUT44168A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT20617/85A IT1183574B (it) 1985-05-08 1985-05-08 Metodo per ottenere una sospensione estemporanea omogenea di microcapsule
PCT/EP1986/000280 WO1986006626A1 (en) 1985-05-08 1986-05-02 Method of preparing an extemporaneous homogeneous microcapsule suspension

Publications (1)

Publication Number Publication Date
HUT44168A true HUT44168A (en) 1988-02-29

Family

ID=11169617

Family Applications (1)

Application Number Title Priority Date Filing Date
HU863345A HUT44168A (en) 1985-05-08 1986-05-02 Process for production of composition assuring eventual homogene suspension of particles containing active substance

Country Status (19)

Country Link
US (1) US5008117A (hu)
EP (1) EP0222856B1 (hu)
JP (1) JP2609597B2 (hu)
KR (1) KR900000212B1 (hu)
AT (1) ATE59287T1 (hu)
AU (1) AU589644B2 (hu)
CA (1) CA1274144A (hu)
DE (1) DE3676642D1 (hu)
DK (1) DK157730C (hu)
ES (1) ES8707103A1 (hu)
FI (1) FI86596C (hu)
HU (1) HUT44168A (hu)
IT (1) IT1183574B (hu)
NO (1) NO171949C (hu)
NZ (1) NZ216062A (hu)
PT (1) PT82541B (hu)
RU (1) RU2059409C1 (hu)
WO (1) WO1986006626A1 (hu)
ZA (1) ZA863399B (hu)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
GB8702411D0 (en) * 1987-02-03 1987-03-11 Zyma Sa Swellable pellets
US5064650A (en) * 1988-04-19 1991-11-12 Southwest Research Institute Controlled-release salt sensitive capsule for oral use and adhesive system
JPH03504968A (ja) * 1988-04-19 1991-10-31 サウスウェスト・リサーチ・インスティチュート 塩感受性シェル物質を有するカプセルからの活性成分の制御放出
FR2634376B1 (fr) * 1988-07-21 1992-04-17 Farmalyoc Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation
NZ234143A (en) * 1989-06-28 1991-10-25 Mcneil Ppc Inc Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents
US5112604A (en) * 1989-09-01 1992-05-12 Riker Laboratories, Inc. Oral suspension formulation
IT1246350B (it) * 1990-07-11 1994-11-17 Eurand Int Metodo per ottenere una rapida sospensione in acqua di farmaci insolubili
US5300302A (en) * 1990-10-04 1994-04-05 Nestec S.A. Pharmaceutical composition in gel form in a dispensing package
US5252337A (en) * 1991-06-25 1993-10-12 Eurand America, Inc. Controlled release calcium channel blocker microcapsules
US5599556A (en) * 1991-12-31 1997-02-04 Abbott Laboratories Prolamine coatings for taste masking
US5272137A (en) * 1992-02-14 1993-12-21 Mcneil-Pfc, Inc. Aqueous pharmaceutical suspension for pharmaceutical actives
US5540912A (en) * 1992-03-30 1996-07-30 Alza Corporation Viscous suspensions of controlled-release drug particles
ZA932273B (en) * 1992-03-30 1993-11-26 Alza Corp Additives for bioerodible polymers to regulate degradation
CZ283428B6 (cs) * 1992-04-30 1998-04-15 Schering Corporation Stabilní hydratovaný suchý práškový cefalosporin vhodný pro orální aplikaci ve formě suspenze
US5422122A (en) * 1992-08-04 1995-06-06 Eurand America, Incorporated Controlled release potassium chloride tablet
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
CA2121435C (en) * 1993-04-16 2002-01-22 Sheila M. Ratnaraj Aqueous pharmaceutical suspension and process for preparation thereof
GB2318511A (en) * 1996-10-23 1998-04-29 Eurand Int Process for the preparation of a pharmaceutical composition for rapid suspension in water
UA65607C2 (uk) 1998-03-04 2004-04-15 Орто-Макнейл Фармацевтикал, Інк. Фармацевтична композиція (варіанти) та спосіб її приготування
GB9822170D0 (en) * 1998-10-13 1998-12-02 Danbioyst Uk Ltd Novel formulations of fexofenadine
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6159491A (en) * 1999-02-12 2000-12-12 Biovector Technologies, Inc. Prolonged release bioadhesive vaginal gel dosage form
US6500462B1 (en) 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
US6932861B2 (en) * 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
WO2002043694A2 (en) 2000-11-28 2002-06-06 Fmc Corporation Edible pga(propylene glycol alginate) coating composition
WO2002048141A1 (en) * 2000-12-11 2002-06-20 Takeda Chemical Industries, Ltd. Medicinal compositions improved in solublity in water
JP2004168703A (ja) * 2002-11-20 2004-06-17 Shin Etsu Chem Co Ltd マイクロカプセル及びその製造方法
US20040170686A1 (en) * 2003-01-31 2004-09-02 Fredrickson Jennifer K. Suspension vehicle for coated drug particles
US20040191326A1 (en) * 2003-03-31 2004-09-30 Reo Joseph P. Taste-masking vehicle for coated oxazolidinone particles
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
US20050118194A1 (en) * 2003-12-01 2005-06-02 Sin Yoke M. Oral vaccine, method for its preparation and use thereof
US20060134210A1 (en) * 2004-12-22 2006-06-22 Astrazeneca Ab Solid dosage form comprising proton pump inhibitor and suspension made thereof
WO2018130876A1 (en) * 2017-01-10 2018-07-19 Dukebox Sp. Z O. O. A method of manufacturing a suspension of nanoparticles of potassium salt or magnesium salt
CN113453662A (zh) 2019-02-22 2021-09-28 康特伦英国斯温顿捷迪斯有限公司 储存期间药物颗粒包衣材料的团聚最小化以稳定化药物产品的崩解时间
GB2597577B (en) 2019-02-22 2023-09-20 Catalent Uk Swindon Zydis Ltd Minimizing agglomeration, aeration, and preserving the coating of pharmaceutical compositions comprising ibuprofen
EP3927322B1 (en) * 2019-02-22 2023-08-16 Catalent U.K. Swindon Zydis Limited Minimizing aeration of suspensions during in-line mixing
RU2731599C1 (ru) * 2019-07-17 2020-09-04 Общество с ограниченной ответственностью "РУСИНТЕХ" Способ получения микрокапсулированного термоактивируемого огнегасящего агента

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB844772A (en) * 1956-04-19 1960-08-17 Pfizer & Co C Granular pharmaceutical compositions and process for preparing same
FR2077696B1 (hu) * 1970-02-06 1973-03-16 Synthelabo
DE2211019C3 (de) * 1972-03-08 1980-08-28 Bayer Ag, 5090 Leverkusen Geschmacksverbessernde Formulierungen oraler Penicilline
US4155741A (en) * 1974-05-01 1979-05-22 Stauffer Chemical Company Stable suspension system for microencapsulated flowable formulations, and method of preparing stable suspension of microcapsules
US4126672A (en) * 1976-02-04 1978-11-21 Hoffmann-La Roche Inc. Sustained release pharmaceutical capsules
US4189499A (en) * 1977-03-16 1980-02-19 Biochefarm S.A. Lysine 4-allyloxy-3-chlorophenylacetate and method of its preparation
IT1148784B (it) * 1980-04-09 1986-12-03 Eurand Spa Procedimento per la preparazione di microcapsule in un veicolo liquido
IT1209276B (it) * 1980-11-05 1989-07-16 Magis Farmaceutici Composizione farmaceutica per la somministrazione orale del metilestere dell'acido 13a-etil-2,3,5,6,12,13,13a,13b-ottaidro-12-idrossi1h-indolo-[3,2,1-de] pirido [3,2,1-ij] [1,5] naftiridina -12-carbossilico

Also Published As

Publication number Publication date
DK7487D0 (da) 1987-01-07
DE3676642D1 (de) 1991-02-07
KR870700209A (ko) 1987-05-30
EP0222856B1 (en) 1990-12-27
FI865336A0 (fi) 1986-12-30
FI86596B (fi) 1992-06-15
EP0222856A1 (en) 1987-05-27
JPS62502859A (ja) 1987-11-12
AU5903186A (en) 1986-12-04
CA1274144A (en) 1990-09-18
PT82541B (pt) 1988-03-03
US5008117A (en) 1991-04-16
WO1986006626A1 (en) 1986-11-20
KR900000212B1 (ko) 1990-01-23
NO865162L (no) 1986-12-18
PT82541A (en) 1986-06-01
ES554777A0 (es) 1987-07-16
DK157730B (da) 1990-02-12
FI865336A (fi) 1986-12-30
DK7487A (da) 1987-01-07
ES8707103A1 (es) 1987-07-16
NZ216062A (en) 1989-07-27
FI86596C (fi) 1992-09-25
IT8520617A0 (it) 1985-05-08
NO171949C (no) 1993-05-26
IT1183574B (it) 1987-10-22
AU589644B2 (en) 1989-10-19
JP2609597B2 (ja) 1997-05-14
ATE59287T1 (de) 1991-01-15
DK157730C (da) 1990-07-16
ZA863399B (en) 1987-01-28
RU2059409C1 (ru) 1996-05-10
NO171949B (no) 1993-02-15

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