ZA825515B - New derivatives of pyridazine active on the central nervous system - Google Patents
New derivatives of pyridazine active on the central nervous systemInfo
- Publication number
- ZA825515B ZA825515B ZA825515A ZA825515A ZA825515B ZA 825515 B ZA825515 B ZA 825515B ZA 825515 A ZA825515 A ZA 825515A ZA 825515 A ZA825515 A ZA 825515A ZA 825515 B ZA825515 B ZA 825515B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyridazine
- active
- nervous system
- central nervous
- new derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8115546A FR2511366A1 (fr) | 1981-08-11 | 1981-08-11 | Nouveaux derives de la pyridazine, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA825515B true ZA825515B (en) | 1983-06-29 |
Family
ID=9261385
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA825515A ZA825515B (en) | 1981-08-11 | 1982-07-30 | New derivatives of pyridazine active on the central nervous system |
Country Status (30)
Country | Link |
---|---|
US (1) | US4710499A (da) |
EP (1) | EP0073161B1 (da) |
JP (1) | JPS5838263A (da) |
KR (1) | KR880002711B1 (da) |
AR (1) | AR231537A1 (da) |
AT (1) | ATE23042T1 (da) |
AU (1) | AU579570B2 (da) |
CA (1) | CA1179347A (da) |
CS (1) | CS239929B2 (da) |
DD (1) | DD202550A5 (da) |
DE (1) | DE3273893D1 (da) |
DK (1) | DK148596C (da) |
EG (1) | EG15749A (da) |
ES (1) | ES8305736A1 (da) |
FI (1) | FI72970C (da) |
FR (1) | FR2511366A1 (da) |
GR (1) | GR76236B (da) |
HU (1) | HU189608B (da) |
IE (1) | IE53493B1 (da) |
IL (1) | IL66424A (da) |
MA (1) | MA19559A1 (da) |
NO (1) | NO158871C (da) |
NZ (1) | NZ201553A (da) |
OA (1) | OA07179A (da) |
PH (1) | PH18921A (da) |
PL (1) | PL137200B1 (da) |
PT (1) | PT75372B (da) |
SU (1) | SU1356960A3 (da) |
YU (1) | YU171682A (da) |
ZA (1) | ZA825515B (da) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2539741A1 (fr) * | 1983-01-21 | 1984-07-27 | Sanofi Sa | Composes a noyau heterocyclique diazote, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent |
US5001125A (en) * | 1984-03-26 | 1991-03-19 | Janssen Pharmaceutica N.V. | Anti-virally active pyridazinamines |
JPS60218377A (ja) * | 1984-04-16 | 1985-11-01 | Mitsubishi Yuka Yakuhin Kk | 4−フエニルフタラジン誘導体及びそれを有効成分とする循環改善剤 |
DE3664772D1 (en) * | 1985-01-14 | 1989-09-07 | Boehringer Ingelheim Kg | 12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use |
US5106973A (en) * | 1987-11-23 | 1992-04-21 | Janssen Pharmaceutica N.V. | Pyridzainamine derivatives |
DE69408598T2 (de) | 1993-06-08 | 1998-09-17 | Vertex Pharmaceuticals Inc Cam | Pyridazine als Interleukin-1-beta Verwandlungsenzym Inhibitoren |
US20100210590A1 (en) * | 1995-09-27 | 2010-08-19 | Northwestern University | Compositions and treatments for seizure-related disorders |
GB9707693D0 (en) * | 1997-04-16 | 1997-06-04 | Smithkline Beecham Plc | Novel method of treatment |
WO2003018563A1 (en) * | 2001-08-31 | 2003-03-06 | Northwestern University | Anti-inflammatory and protein kinase inhibitor composition and method of use |
JP2008518955A (ja) * | 2004-11-02 | 2008-06-05 | ノースウェスタン ユニバーシティ | ピリダジン化合物および方法 |
CN101087766B (zh) | 2004-11-02 | 2011-09-07 | 西北大学 | 哒嗪化合物、组合物和方法 |
CA2650711A1 (en) * | 2006-04-28 | 2007-11-08 | Northwestern University | Compositions and treatments using pyridazine compounds and cholinesterase inhibitors |
CA2650704A1 (en) * | 2006-04-28 | 2007-11-08 | Northwestern University | Salts of pyridazine compounds |
BRPI0710938A2 (pt) * | 2006-04-28 | 2012-06-26 | Univ Northwestern | formulações contendo compostos de piridazina para o tratamento de doenças neuroinflamatórias |
JP2010520223A (ja) * | 2007-03-02 | 2010-06-10 | ノースウェスタン ユニバーシティ | 発作関連障害のための組成物および方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1345880A (en) * | 1971-06-18 | 1974-02-06 | Cepbepe | Pyridazine derivatives |
FR2473522A1 (fr) * | 1980-01-16 | 1981-07-17 | Synthelabo | Nouveaux derives substitues de dihydro-2,3 imidazo(1,2-b)pyridazines et les medicaments, utiles notamment comme antidepresseurs, qui en contiennent |
-
1981
- 1981-08-11 FR FR8115546A patent/FR2511366A1/fr active Granted
-
1982
- 1982-07-26 GR GR68872A patent/GR76236B/el unknown
- 1982-07-28 IE IE1822/82A patent/IE53493B1/en not_active IP Right Cessation
- 1982-07-29 IL IL66424A patent/IL66424A/xx unknown
- 1982-07-30 DE DE8282401426T patent/DE3273893D1/de not_active Expired
- 1982-07-30 EP EP82401426A patent/EP0073161B1/fr not_active Expired
- 1982-07-30 ZA ZA825515A patent/ZA825515B/xx unknown
- 1982-07-30 AT AT82401426T patent/ATE23042T1/de not_active IP Right Cessation
- 1982-08-02 MA MA19770A patent/MA19559A1/fr unknown
- 1982-08-03 PT PT75372A patent/PT75372B/pt not_active IP Right Cessation
- 1982-08-06 YU YU01716/82A patent/YU171682A/xx unknown
- 1982-08-06 HU HU822546A patent/HU189608B/hu not_active IP Right Cessation
- 1982-08-07 EG EG478/82A patent/EG15749A/xx active
- 1982-08-09 CS CS825913A patent/CS239929B2/cs unknown
- 1982-08-09 PL PL1982237836A patent/PL137200B1/pl unknown
- 1982-08-09 FI FI822768A patent/FI72970C/fi not_active IP Right Cessation
- 1982-08-10 OA OA57771A patent/OA07179A/xx unknown
- 1982-08-10 NZ NZ201553A patent/NZ201553A/en unknown
- 1982-08-10 ES ES514887A patent/ES8305736A1/es not_active Expired
- 1982-08-10 AU AU87029/82A patent/AU579570B2/en not_active Ceased
- 1982-08-10 PH PH27701A patent/PH18921A/en unknown
- 1982-08-10 SU SU823475703A patent/SU1356960A3/ru active
- 1982-08-10 NO NO822717A patent/NO158871C/no unknown
- 1982-08-10 DK DK358782A patent/DK148596C/da not_active IP Right Cessation
- 1982-08-10 AR AR290279A patent/AR231537A1/es active
- 1982-08-10 CA CA000409143A patent/CA1179347A/en not_active Expired
- 1982-08-11 DD DD82242426A patent/DD202550A5/de unknown
- 1982-08-11 JP JP57138671A patent/JPS5838263A/ja active Granted
- 1982-08-11 KR KR8203609A patent/KR880002711B1/ko active
-
1984
- 1984-08-07 US US06/638,363 patent/US4710499A/en not_active Expired - Fee Related
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