PH18921A - New derivatives of pyridazine acitve on the central nervous system - Google Patents
New derivatives of pyridazine acitve on the central nervous systemInfo
- Publication number
- PH18921A PH18921A PH27701A PH27701A PH18921A PH 18921 A PH18921 A PH 18921A PH 27701 A PH27701 A PH 27701A PH 27701 A PH27701 A PH 27701A PH 18921 A PH18921 A PH 18921A
- Authority
- PH
- Philippines
- Prior art keywords
- acitve
- pyridazine
- nervous system
- central nervous
- new derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8115546A FR2511366A1 (fr) | 1981-08-11 | 1981-08-11 | Nouveaux derives de la pyridazine, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH18921A true PH18921A (en) | 1985-11-11 |
Family
ID=9261385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH27701A PH18921A (en) | 1981-08-11 | 1982-08-10 | New derivatives of pyridazine acitve on the central nervous system |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US4710499A (da) |
| EP (1) | EP0073161B1 (da) |
| JP (1) | JPS5838263A (da) |
| KR (1) | KR880002711B1 (da) |
| AR (1) | AR231537A1 (da) |
| AT (1) | ATE23042T1 (da) |
| AU (1) | AU579570B2 (da) |
| CA (1) | CA1179347A (da) |
| CS (1) | CS239929B2 (da) |
| DD (1) | DD202550A5 (da) |
| DE (1) | DE3273893D1 (da) |
| DK (1) | DK148596C (da) |
| EG (1) | EG15749A (da) |
| ES (1) | ES514887A0 (da) |
| FI (1) | FI72970C (da) |
| FR (1) | FR2511366A1 (da) |
| GR (1) | GR76236B (da) |
| HU (1) | HU189608B (da) |
| IE (1) | IE53493B1 (da) |
| IL (1) | IL66424A (da) |
| MA (1) | MA19559A1 (da) |
| NO (1) | NO158871C (da) |
| NZ (1) | NZ201553A (da) |
| OA (1) | OA07179A (da) |
| PH (1) | PH18921A (da) |
| PL (1) | PL137200B1 (da) |
| PT (1) | PT75372B (da) |
| SU (1) | SU1356960A3 (da) |
| YU (1) | YU171682A (da) |
| ZA (1) | ZA825515B (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2539741A1 (fr) * | 1983-01-21 | 1984-07-27 | Sanofi Sa | Composes a noyau heterocyclique diazote, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent |
| US5001125A (en) * | 1984-03-26 | 1991-03-19 | Janssen Pharmaceutica N.V. | Anti-virally active pyridazinamines |
| JPS60218377A (ja) * | 1984-04-16 | 1985-11-01 | Mitsubishi Yuka Yakuhin Kk | ４−フエニルフタラジン誘導体及びそれを有効成分とする循環改善剤 |
| DE3664772D1 (en) * | 1985-01-14 | 1989-09-07 | Boehringer Ingelheim Kg | 12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use |
| US5106973A (en) * | 1987-11-23 | 1992-04-21 | Janssen Pharmaceutica N.V. | Pyridzainamine derivatives |
| DE69408598T2 (de) | 1993-06-08 | 1998-09-17 | Vertex Pharmaceuticals Inc Cam | Pyridazine als Interleukin-1-beta Verwandlungsenzym Inhibitoren |
| US20100210590A1 (en) * | 1995-09-27 | 2010-08-19 | Northwestern University | Compositions and treatments for seizure-related disorders |
| GB9707693D0 (en) * | 1997-04-16 | 1997-06-04 | Smithkline Beecham Plc | Novel method of treatment |
| US20030176437A1 (en) * | 2001-08-31 | 2003-09-18 | D.M. Watterson | Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death |
| WO2006050389A2 (en) | 2004-11-02 | 2006-05-11 | Northwestern University | Pyridazine compounds, compositions and methods |
| CA2589102C (en) * | 2004-11-02 | 2013-08-13 | Northwestern University | Pyridazine compounds and methods for using the compounds to treat inflammatory diseases |
| CA2650704A1 (en) * | 2006-04-28 | 2007-11-08 | Northwestern University | Salts of pyridazine compounds |
| EP2063894B1 (en) * | 2006-04-28 | 2019-08-28 | Northwestern University | Formulations containing pyridazine compounds for treating neuroinflammatory diseases |
| CA2650711A1 (en) * | 2006-04-28 | 2007-11-08 | Northwestern University | Compositions and treatments using pyridazine compounds and cholinesterase inhibitors |
| EP2131839A2 (en) * | 2007-03-02 | 2009-12-16 | Northwestern University | Compositions comprising derivatives of 3-phenylpyridazine for treating seizure-related disorders |
| WO2024148148A1 (en) * | 2023-01-04 | 2024-07-11 | The Trustees Of Columbia University In The City Of New York | Pyridazine based small molecule inhibitor of cognitive impairment |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1345880A (en) * | 1971-06-18 | 1974-02-06 | Cepbepe | Pyridazine derivatives |
| FR2473522A1 (fr) * | 1980-01-16 | 1981-07-17 | Synthelabo | Nouveaux derives substitues de dihydro-2,3 imidazo(1,2-b)pyridazines et les medicaments, utiles notamment comme antidepresseurs, qui en contiennent |
-
1981
- 1981-08-11 FR FR8115546A patent/FR2511366A1/fr active Granted
-
1982
- 1982-07-26 GR GR68872A patent/GR76236B/el unknown
- 1982-07-28 IE IE1822/82A patent/IE53493B1/en not_active IP Right Cessation
- 1982-07-29 IL IL66424A patent/IL66424A/xx unknown
- 1982-07-30 DE DE8282401426T patent/DE3273893D1/de not_active Expired
- 1982-07-30 AT AT82401426T patent/ATE23042T1/de not_active IP Right Cessation
- 1982-07-30 EP EP82401426A patent/EP0073161B1/fr not_active Expired
- 1982-07-30 ZA ZA825515A patent/ZA825515B/xx unknown
- 1982-08-02 MA MA19770A patent/MA19559A1/fr unknown
- 1982-08-03 PT PT75372A patent/PT75372B/pt not_active IP Right Cessation
- 1982-08-06 HU HU822546A patent/HU189608B/hu not_active IP Right Cessation
- 1982-08-06 YU YU01716/82A patent/YU171682A/xx unknown
- 1982-08-07 EG EG478/82A patent/EG15749A/xx active
- 1982-08-09 CS CS825913A patent/CS239929B2/cs unknown
- 1982-08-09 PL PL1982237836A patent/PL137200B1/pl unknown
- 1982-08-09 FI FI822768A patent/FI72970C/fi not_active IP Right Cessation
- 1982-08-10 SU SU823475703A patent/SU1356960A3/ru active
- 1982-08-10 PH PH27701A patent/PH18921A/en unknown
- 1982-08-10 CA CA000409143A patent/CA1179347A/en not_active Expired
- 1982-08-10 AR AR290279A patent/AR231537A1/es active
- 1982-08-10 NO NO822717A patent/NO158871C/no unknown
- 1982-08-10 AU AU87029/82A patent/AU579570B2/en not_active Ceased
- 1982-08-10 NZ NZ201553A patent/NZ201553A/en unknown
- 1982-08-10 ES ES514887A patent/ES514887A0/es active Granted
- 1982-08-10 OA OA57771A patent/OA07179A/xx unknown
- 1982-08-10 DK DK358782A patent/DK148596C/da not_active IP Right Cessation
- 1982-08-11 KR KR8203609A patent/KR880002711B1/ko active
- 1982-08-11 JP JP57138671A patent/JPS5838263A/ja active Granted
- 1982-08-11 DD DD82242426A patent/DD202550A5/de unknown
-
1984
- 1984-08-07 US US06/638,363 patent/US4710499A/en not_active Expired - Fee Related
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