OA07179A - Nouveaux dérivés de la pyridazine actifs sur le système nerveux central. - Google Patents

Nouveaux dérivés de la pyridazine actifs sur le système nerveux central.

Info

Publication number
OA07179A
OA07179A OA57771A OA57771A OA07179A OA 07179 A OA07179 A OA 07179A OA 57771 A OA57771 A OA 57771A OA 57771 A OA57771 A OA 57771A OA 07179 A OA07179 A OA 07179A
Authority
OA
OAPI
Prior art keywords
nervous system
central nervous
pyridazine derivatives
derivatives active
new pyridazine
Prior art date
Application number
OA57771A
Other languages
English (en)
French (fr)
Inventor
Camille Wermuth
Jean-Pierre Chambon
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of OA07179A publication Critical patent/OA07179A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
OA57771A 1981-08-11 1982-08-10 Nouveaux dérivés de la pyridazine actifs sur le système nerveux central. OA07179A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8115546A FR2511366A1 (fr) 1981-08-11 1981-08-11 Nouveaux derives de la pyridazine, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent

Publications (1)

Publication Number Publication Date
OA07179A true OA07179A (fr) 1984-04-30

Family

ID=9261385

Family Applications (1)

Application Number Title Priority Date Filing Date
OA57771A OA07179A (fr) 1981-08-11 1982-08-10 Nouveaux dérivés de la pyridazine actifs sur le système nerveux central.

Country Status (30)

Country Link
US (1) US4710499A (da)
EP (1) EP0073161B1 (da)
JP (1) JPS5838263A (da)
KR (1) KR880002711B1 (da)
AR (1) AR231537A1 (da)
AT (1) ATE23042T1 (da)
AU (1) AU579570B2 (da)
CA (1) CA1179347A (da)
CS (1) CS239929B2 (da)
DD (1) DD202550A5 (da)
DE (1) DE3273893D1 (da)
DK (1) DK148596C (da)
EG (1) EG15749A (da)
ES (1) ES514887A0 (da)
FI (1) FI72970C (da)
FR (1) FR2511366A1 (da)
GR (1) GR76236B (da)
HU (1) HU189608B (da)
IE (1) IE53493B1 (da)
IL (1) IL66424A (da)
MA (1) MA19559A1 (da)
NO (1) NO158871C (da)
NZ (1) NZ201553A (da)
OA (1) OA07179A (da)
PH (1) PH18921A (da)
PL (1) PL137200B1 (da)
PT (1) PT75372B (da)
SU (1) SU1356960A3 (da)
YU (1) YU171682A (da)
ZA (1) ZA825515B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2539741A1 (fr) * 1983-01-21 1984-07-27 Sanofi Sa Composes a noyau heterocyclique diazote, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
JPS60218377A (ja) * 1984-04-16 1985-11-01 Mitsubishi Yuka Yakuhin Kk ４−フエニルフタラジン誘導体及びそれを有効成分とする循環改善剤
DE3664772D1 (en) * 1985-01-14 1989-09-07 Boehringer Ingelheim Kg 12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use
US5106973A (en) * 1987-11-23 1992-04-21 Janssen Pharmaceutica N.V. Pyridzainamine derivatives
DE69408598T2 (de) 1993-06-08 1998-09-17 Vertex Pharmaceuticals Inc Cam Pyridazine als Interleukin-1-beta Verwandlungsenzym Inhibitoren
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
GB9707693D0 (en) * 1997-04-16 1997-06-04 Smithkline Beecham Plc Novel method of treatment
US20030176437A1 (en) * 2001-08-31 2003-09-18 D.M. Watterson Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
WO2006050389A2 (en) 2004-11-02 2006-05-11 Northwestern University Pyridazine compounds, compositions and methods
CA2589102C (en) * 2004-11-02 2013-08-13 Northwestern University Pyridazine compounds and methods for using the compounds to treat inflammatory diseases
CA2650704A1 (en) * 2006-04-28 2007-11-08 Northwestern University Salts of pyridazine compounds
EP2063894B1 (en) * 2006-04-28 2019-08-28 Northwestern University Formulations containing pyridazine compounds for treating neuroinflammatory diseases
CA2650711A1 (en) * 2006-04-28 2007-11-08 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
EP2131839A2 (en) * 2007-03-02 2009-12-16 Northwestern University Compositions comprising derivatives of 3-phenylpyridazine for treating seizure-related disorders
WO2024148148A1 (en) * 2023-01-04 2024-07-11 The Trustees Of Columbia University In The City Of New York Pyridazine based small molecule inhibitor of cognitive impairment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives
FR2473522A1 (fr) * 1980-01-16 1981-07-17 Synthelabo Nouveaux derives substitues de dihydro-2,3 imidazo(1,2-b)pyridazines et les medicaments, utiles notamment comme antidepresseurs, qui en contiennent

Also Published As

Publication number Publication date
FR2511366B1 (da) 1984-12-14
DD202550A5 (de) 1983-09-21
ES8305736A1 (es) 1983-04-16
DK358782A (da) 1983-02-12
US4710499A (en) 1987-12-01
ZA825515B (en) 1983-06-29
AU8702982A (en) 1983-05-12
NO822717L (no) 1983-02-14
KR840001147A (ko) 1984-03-28
HU189608B (en) 1986-07-28
FI822768L (fi) 1983-02-11
PT75372A (en) 1982-09-01
FI822768A0 (fi) 1982-08-09
ATE23042T1 (de) 1986-11-15
AR231537A1 (es) 1984-12-28
PH18921A (en) 1985-11-11
DK148596C (da) 1986-01-13
FR2511366A1 (fr) 1983-02-18
EP0073161B1 (fr) 1986-10-22
IE821822L (en) 1983-02-11
EG15749A (en) 1986-09-30
YU171682A (en) 1985-03-20
PT75372B (en) 1984-12-10
NZ201553A (en) 1985-08-16
IE53493B1 (en) 1988-11-23
MA19559A1 (fr) 1983-04-01
IL66424A (en) 1985-10-31
NO158871B (no) 1988-08-01
CS239929B2 (en) 1986-01-16
EP0073161A1 (fr) 1983-03-02
FI72970C (fi) 1987-08-10
SU1356960A3 (ru) 1987-11-30
PL237836A1 (en) 1983-02-28
IL66424A0 (en) 1982-11-30
FI72970B (fi) 1987-04-30
DK148596B (da) 1985-08-12
GR76236B (da) 1984-08-04
NO158871C (no) 1988-11-09
JPS5838263A (ja) 1983-03-05
PL137200B1 (en) 1986-05-31
CA1179347A (en) 1984-12-11
JPH0456032B2 (da) 1992-09-07
DE3273893D1 (en) 1986-11-27
KR880002711B1 (ko) 1988-12-26
AU579570B2 (en) 1988-12-01
ES514887A0 (es) 1983-04-16

Similar Documents

Publication Publication Date Title
OA07175A (fr) Nouveaux dérivés de la pyridazine actifs sur le système nerveux central.
IT7921537A0 (it) Sedile per bambini, su veicoli.
FI861210A (fi) N,n'-dialkylguanidinodipeptider.
DE3762082D1 (de) Funktions-sitzmoebel.
DE3682695D1 (de) Fahrzeugsitz.
OA07179A (fr) Nouveaux dérivés de la pyridazine actifs sur le système nerveux central.
ES514598A0 (es) Sistema de administracion parenteral.
DE3767772D1 (de) Gefahrenmeldeanlage.
ES262048Y (es) Hebilla perfeccionada .
DE3780931D1 (de) Selbsttaetiges gelenktes fahrzeugsystem.
DE3888530D1 (de) 3'-Azido-2',3'-dideoxynucleosid-5'-phosphonate.
ES517281A0 (es) Procedimiento para la obtencion de 4,4'-diisocianatodifenilmetano.
NO851292L (no) Stablesystem.
FI860561A0 (fi) Foerfarande foer framstaellning av 2 (4,5-1h-imidazol-2-yl)-2,3-dihydro-indolderivat.
DE3670844D1 (de) 2,4-dioxopyrrolo(2,3-c)pyrrole.
ES511914A0 (es) Derivados de isoquinolina 1,5-sustituidos.
ATE74912T1 (de) 2,2'-bi-1h-imidazole.
FI863139A (fi) 5-klor-s-triazolo(4,3-a)-pyridin-7- carboxylsyror.
DE3687800D1 (de) Netzwerksystem.
OA08208A (fr) Ethylphosphonoditioate de s,s-ditertiobutyle.
ES512695A0 (es) "procedimiento de obtencion de derivados metilquinoxalin-1,4-dioxido".
KR870000795U (ko) 상.하.좌,우 조정 파이프
ES261724Y (es) Caja-estuche, perfeccionada.
ES262135Y (es) "asiento de campana".
IT8421990V0 (it) Impianto tipografico perfezionato.