PT75372B - Process for the preparation of pyridazine derivatives - Google Patents

Process for the preparation of pyridazine derivatives

Info

Publication number
PT75372B
PT75372B PT75372A PT7537282A PT75372B PT 75372 B PT75372 B PT 75372B PT 75372 A PT75372 A PT 75372A PT 7537282 A PT7537282 A PT 7537282A PT 75372 B PT75372 B PT 75372B
Authority
PT
Portugal
Prior art keywords
preparation
pyridazine derivatives
pyridazine
derivatives
Prior art date
Application number
PT75372A
Other languages
English (en)
Other versions
PT75372A (en
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of PT75372A publication Critical patent/PT75372A/pt
Publication of PT75372B publication Critical patent/PT75372B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/34—Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT75372A 1981-08-11 1982-08-03 Process for the preparation of pyridazine derivatives PT75372B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8115546A FR2511366A1 (fr) 1981-08-11 1981-08-11 Nouveaux derives de la pyridazine, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent

Publications (2)

Publication Number Publication Date
PT75372A PT75372A (en) 1982-09-01
PT75372B true PT75372B (en) 1984-12-10

Family

ID=9261385

Family Applications (1)

Application Number Title Priority Date Filing Date
PT75372A PT75372B (en) 1981-08-11 1982-08-03 Process for the preparation of pyridazine derivatives

Country Status (30)

Country Link
US (1) US4710499A (pt)
EP (1) EP0073161B1 (pt)
JP (1) JPS5838263A (pt)
KR (1) KR880002711B1 (pt)
AR (1) AR231537A1 (pt)
AT (1) ATE23042T1 (pt)
AU (1) AU579570B2 (pt)
CA (1) CA1179347A (pt)
CS (1) CS239929B2 (pt)
DD (1) DD202550A5 (pt)
DE (1) DE3273893D1 (pt)
DK (1) DK148596C (pt)
EG (1) EG15749A (pt)
ES (1) ES8305736A1 (pt)
FI (1) FI72970C (pt)
FR (1) FR2511366A1 (pt)
GR (1) GR76236B (pt)
HU (1) HU189608B (pt)
IE (1) IE53493B1 (pt)
IL (1) IL66424A (pt)
MA (1) MA19559A1 (pt)
NO (1) NO158871C (pt)
NZ (1) NZ201553A (pt)
OA (1) OA07179A (pt)
PH (1) PH18921A (pt)
PL (1) PL137200B1 (pt)
PT (1) PT75372B (pt)
SU (1) SU1356960A3 (pt)
YU (1) YU171682A (pt)
ZA (1) ZA825515B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2539741A1 (fr) * 1983-01-21 1984-07-27 Sanofi Sa Composes a noyau heterocyclique diazote, leur procede de preparation et les medicaments, actifs sur le systeme nerveux central, qui en contiennent
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
JPS60218377A (ja) * 1984-04-16 1985-11-01 Mitsubishi Yuka Yakuhin Kk ４−フエニルフタラジン誘導体及びそれを有効成分とする循環改善剤
DE3664772D1 (en) * 1985-01-14 1989-09-07 Boehringer Ingelheim Kg 12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use
US5106973A (en) * 1987-11-23 1992-04-21 Janssen Pharmaceutica N.V. Pyridzainamine derivatives
ES2114654T3 (es) * 1993-06-08 1998-06-01 Vertex Pharma Piridazinas como inhibidores de la enzima de conversion de la interleuquina-1beta.
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
GB9707693D0 (en) * 1997-04-16 1997-06-04 Smithkline Beecham Plc Novel method of treatment
EP1430033A4 (en) * 2001-08-31 2004-12-15 Univ Northwestern PROTEIN KINASE ANTI-INFLAMMATORY AND INHIBITOR COMPOSITION AND METHOD OF USE
ES2543813T3 (es) 2004-11-02 2015-08-24 Northwestern University Compuestos de piridazina para el tratamiento de enfermedades inflamatorias
WO2006050359A2 (en) * 2004-11-02 2006-05-11 Northwestern University Pyridazine compounds and methods
WO2007127474A2 (en) * 2006-04-28 2007-11-08 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
WO2007127375A2 (en) 2006-04-28 2007-11-08 Northwestern University Formulations containing pyridazine compounds for treating neuroinflammatory diseases
US20100168120A1 (en) * 2006-04-28 2010-07-01 Neuromedix Inc. Salts of pyridazine compounds
EP2131839A2 (en) * 2007-03-02 2009-12-16 Northwestern University Compositions comprising derivatives of 3-phenylpyridazine for treating seizure-related disorders
WO2024148148A1 (en) * 2023-01-04 2024-07-11 The Trustees Of Columbia University In The City Of New York Pyridazine based small molecule inhibitor of cognitive impairment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives
FR2473522A1 (fr) * 1980-01-16 1981-07-17 Synthelabo Nouveaux derives substitues de dihydro-2,3 imidazo(1,2-b)pyridazines et les medicaments, utiles notamment comme antidepresseurs, qui en contiennent

Also Published As

Publication number Publication date
FR2511366B1 (pt) 1984-12-14
KR880002711B1 (ko) 1988-12-26
NZ201553A (en) 1985-08-16
IL66424A (en) 1985-10-31
NO158871B (no) 1988-08-01
JPS5838263A (ja) 1983-03-05
ZA825515B (en) 1983-06-29
AU579570B2 (en) 1988-12-01
DK148596B (da) 1985-08-12
GR76236B (pt) 1984-08-04
PL137200B1 (en) 1986-05-31
PT75372A (en) 1982-09-01
FR2511366A1 (fr) 1983-02-18
IL66424A0 (en) 1982-11-30
DK148596C (da) 1986-01-13
CS239929B2 (en) 1986-01-16
ES514887A0 (es) 1983-04-16
YU171682A (en) 1985-03-20
MA19559A1 (fr) 1983-04-01
PH18921A (en) 1985-11-11
SU1356960A3 (ru) 1987-11-30
KR840001147A (ko) 1984-03-28
NO822717L (no) 1983-02-14
HU189608B (en) 1986-07-28
US4710499A (en) 1987-12-01
CA1179347A (en) 1984-12-11
IE821822L (en) 1983-02-11
EP0073161B1 (fr) 1986-10-22
EP0073161A1 (fr) 1983-03-02
EG15749A (en) 1986-09-30
NO158871C (no) 1988-11-09
FI822768L (fi) 1983-02-11
IE53493B1 (en) 1988-11-23
AR231537A1 (es) 1984-12-28
JPH0456032B2 (pt) 1992-09-07
FI72970C (fi) 1987-08-10
ES8305736A1 (es) 1983-04-16
DD202550A5 (de) 1983-09-21
FI822768A0 (fi) 1982-08-09
PL237836A1 (en) 1983-02-28
OA07179A (fr) 1984-04-30
DE3273893D1 (en) 1986-11-27
AU8702982A (en) 1983-05-12
ATE23042T1 (de) 1986-11-15
DK358782A (da) 1983-02-12
FI72970B (fi) 1987-04-30

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Legal Events

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MM3A Annulment or lapse

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Effective date: 19940611