ZA791616B - Process for making histamine antagonists - Google Patents

Process for making histamine antagonists

Info

Publication number
ZA791616B
ZA791616B ZA791616A ZA791616A ZA791616B ZA 791616 B ZA791616 B ZA 791616B ZA 791616 A ZA791616 A ZA 791616A ZA 791616 A ZA791616 A ZA 791616A ZA 791616 B ZA791616 B ZA 791616B
Authority
ZA
South Africa
Prior art keywords
making
histamine antagonists
histamine
antagonists
making histamine
Prior art date
Application number
ZA791616A
Other languages
English (en)
Inventor
T Brown
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of ZA791616B publication Critical patent/ZA791616B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
ZA791616A 1978-04-11 1979-04-05 Process for making histamine antagonists ZA791616B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1404978 1978-04-11

Publications (1)

Publication Number Publication Date
ZA791616B true ZA791616B (en) 1980-04-30

Family

ID=10034068

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA791616A ZA791616B (en) 1978-04-11 1979-04-05 Process for making histamine antagonists

Country Status (31)

Country Link
US (1) US4523015A (ru)
EP (1) EP0004793B1 (ru)
JP (1) JPS54138580A (ru)
KR (1) KR820002136B1 (ru)
AT (1) AT372956B (ru)
AU (1) AU527202B2 (ru)
CA (1) CA1138453A (ru)
CS (1) CS210684B2 (ru)
CY (1) CY1194A (ru)
DD (1) DD142878A5 (ru)
DE (1) DE2961652D1 (ru)
DK (1) DK147379A (ru)
ES (1) ES479469A1 (ru)
FI (1) FI791143A (ru)
GR (1) GR66986B (ru)
HU (1) HU180081B (ru)
IE (1) IE48080B1 (ru)
IL (1) IL57005A (ru)
IT (1) IT1118476B (ru)
KE (1) KE3284A (ru)
MX (1) MX5898E (ru)
MY (1) MY8500703A (ru)
NO (1) NO791225L (ru)
NZ (1) NZ190122A (ru)
PH (2) PH16240A (ru)
PL (2) PL117998B1 (ru)
PT (1) PT69464A (ru)
RO (1) RO76810A (ru)
SU (2) SU944504A3 (ru)
YU (1) YU84179A (ru)
ZA (1) ZA791616B (ru)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN151188B (ru) * 1978-02-13 1983-03-05 Smith Kline French Lab
CA1140129A (en) * 1979-08-21 1983-01-25 Ronald J. King 4-pyrimidone derivatives
CA1155842A (en) * 1980-03-29 1983-10-25 Thomas H. Brown Compounds
US4352933A (en) * 1981-02-06 1982-10-05 Smithkline Beckman Corporation Chemical methods and intermediates for preparing substituted pyrimidinones
ZA823149B (en) * 1981-05-27 1983-03-30 Smithkline Beckman Corp Chemical process
PT74865B (en) * 1981-05-27 1983-12-07 Smithkline Beckman Corp Process of preparing a 2-(pyridylbutylamino)-pyrimidone and of its pharmaceutically acceptable salts
DK230482A (da) * 1981-05-30 1982-12-01 Smith Kline French Lab Pyrimidonsalt og fremstilling heraf
US4772704A (en) * 1983-09-21 1988-09-20 Bristol-Myers Company 2,5-disubstituted-4(3H)-pyrimidones having histamine H2 -receptor antagonist activity
IL75400A (en) * 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
GB8421427D0 (en) * 1984-08-23 1984-09-26 Smith Kline French Lab Chemical compounds
DE3532880A1 (de) * 1985-09-14 1987-03-26 Basf Ag 1,4-disubstituierte pyrazolderivate
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
CN107698501A (zh) * 2017-10-25 2018-02-16 遵义医学院 5,6‑二甲基‑2‑羟基烟酸的制备工艺
WO2022034121A1 (en) 2020-08-11 2022-02-17 Université De Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE787372A (fr) * 1971-08-09 1973-02-09 Ici Ltd 2-nitroamino-6-hydroxy-4-methylpyrimidines substituees en position 5
GB1383676A (en) * 1972-07-14 1974-02-12 Ici Ltd Process for making diethylamino pyrimidine derivatives
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
US4145546A (en) * 1975-10-02 1979-03-20 Smith Kline & French Laboratories Limited 4-Pyrimidone compounds
IN146736B (ru) * 1975-10-02 1979-08-25 Smith Kline French Lab
US4216318A (en) * 1975-12-29 1980-08-05 Smith Kline & French Laboratories Limited Heterocyclic alkyl 4-pyrimidones
US4154834A (en) * 1975-12-29 1979-05-15 Smith Kline & French Laboratories Limited Substituted isocytosines having histamine H2 -antagonist activity
MW5076A1 (en) * 1975-12-29 1978-02-08 Smith Kline French Lab Pharmacologicalle active compounds
US4227000A (en) * 1978-04-11 1980-10-07 Smith Kline & French Laboratories Limited Intermediates in the process for making histamine antagonists
ZA793392B (en) * 1978-07-15 1980-08-27 Smith Kline French Lab Isoureas and isothioureas

Also Published As

Publication number Publication date
IE790364L (en) 1979-10-11
PH16841A (en) 1984-03-15
ES479469A1 (es) 1979-07-16
DK147379A (da) 1979-10-12
ATA267079A (de) 1983-04-15
IT7967751A0 (it) 1979-04-09
NZ190122A (en) 1982-03-09
AU527202B2 (en) 1983-02-24
PL214792A1 (ru) 1980-03-24
CS210684B2 (en) 1982-01-29
PL118404B1 (en) 1981-10-31
PL117998B1 (en) 1981-09-30
RO76810A (ro) 1981-05-30
DD142878A5 (de) 1980-07-16
US4523015A (en) 1985-06-11
EP0004793A2 (en) 1979-10-17
CY1194A (en) 1983-12-31
NO791225L (no) 1979-10-12
YU84179A (en) 1983-04-30
IL57005A (en) 1983-11-30
GR66986B (ru) 1981-05-15
FI791143A (fi) 1979-10-12
CA1138453A (en) 1982-12-28
EP0004793A3 (en) 1979-11-28
SU944504A3 (ru) 1982-07-15
MY8500703A (en) 1985-12-31
HU180081B (en) 1983-01-28
JPS54138580A (en) 1979-10-27
DE2961652D1 (en) 1982-02-18
AT372956B (de) 1983-12-12
MX5898E (es) 1984-08-22
IE48080B1 (en) 1984-09-19
KR820002136B1 (ko) 1982-11-15
IT1118476B (it) 1986-03-03
SU906376A3 (ru) 1982-02-15
PT69464A (en) 1979-05-01
PH16240A (en) 1983-08-11
AU4571479A (en) 1979-10-18
KE3284A (en) 1983-05-13
EP0004793B1 (en) 1981-12-30

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