ZA783084B - Benzodiazepine compounds processes for their preparation,and pharmaceutical compositions thereof - Google Patents

Benzodiazepine compounds processes for their preparation,and pharmaceutical compositions thereof

Info

Publication number
ZA783084B
ZA783084B ZA783084A ZA783084A ZA783084B ZA 783084 B ZA783084 B ZA 783084B ZA 783084 A ZA783084 A ZA 783084A ZA 783084 A ZA783084 A ZA 783084A ZA 783084 B ZA783084 B ZA 783084B
Authority
ZA
South Africa
Prior art keywords
preparation
pharmaceutical compositions
benzodiazepine compounds
compounds processes
processes
Prior art date
Application number
ZA783084A
Other languages
English (en)
Inventor
M Leitold
G Schmidt
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA783084B publication Critical patent/ZA783084B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA783084A 1977-05-31 1978-05-30 Benzodiazepine compounds processes for their preparation,and pharmaceutical compositions thereof ZA783084B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772724434 DE2724434A1 (de) 1977-05-31 1977-05-31 Neue, in 11-stellung substituierte 5,11-dihydro-6h-pyrido eckige klammer auf 2,3-b eckige klammer zu eckige klammer auf 1,4 eckige klammer zu benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ZA783084B true ZA783084B (en) 1980-02-27

Family

ID=6010263

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA783084A ZA783084B (en) 1977-05-31 1978-05-30 Benzodiazepine compounds processes for their preparation,and pharmaceutical compositions thereof

Country Status (31)

Country Link
US (1) US4213984A (no)
JP (1) JPS543096A (no)
AT (1) AT361491B (no)
AU (1) AU516893B2 (no)
BE (1) BE867638A (no)
BG (2) BG26949A4 (no)
CA (1) CA1109064A (no)
CH (1) CH637652A5 (no)
CS (1) CS207617B2 (no)
DD (1) DD137106A5 (no)
DE (1) DE2724434A1 (no)
DK (1) DK239578A (no)
ES (2) ES470270A1 (no)
FI (1) FI63232C (no)
FR (1) FR2392993A1 (no)
GB (1) GB1571781A (no)
GR (1) GR66164B (no)
HK (1) HK11182A (no)
HU (1) HU180999B (no)
IE (1) IE46907B1 (no)
IL (1) IL54813A (no)
MY (1) MY8200242A (no)
NL (1) NL7805847A (no)
NO (1) NO149313C (no)
NZ (1) NZ187426A (no)
PH (1) PH14609A (no)
PL (2) PL112911B1 (no)
PT (1) PT68112A (no)
SE (1) SE7806288L (no)
SU (1) SU772484A3 (no)
ZA (1) ZA783084B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2053187A (en) * 1979-07-09 1981-02-04 Grissmann Chem Ltd Process for preparing pyrenzepine
IT1130973B (it) * 1980-03-17 1986-06-18 Microsules Argentina Sa De S C Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti
DE3204403A1 (de) * 1982-02-09 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach Neue pyridobenzodiazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3204401A1 (de) * 1982-02-09 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach Pyridobenzodiazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
IT1212742B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Derivati dibenzo [1,4]diazepinonici pirido [1,4] benzodiazepinonici,pirido [1,5] benzodiazepinonici e loro attivita' farmacologica
DE3726908A1 (de) * 1987-08-13 1989-02-23 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820345A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5298508A (en) * 1988-07-19 1994-03-29 The United States Of America As Represented By The Department Of Health And Human Services Irreversible inhibitors of adenosine receptors
US5324832A (en) * 1991-07-03 1994-06-28 The United States Of America As Represented By The Department Of Health And Human Services Muscarinic antagonists
WO1997037667A1 (en) 1996-04-10 1997-10-16 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Use of an a1 adenosine receptor agonist to treat cerebral ischaemia
AU2005263578B2 (en) 2004-07-16 2010-09-02 Proteosys Ag Muscarinic antagonists with PARP and SIR modulating activity as agents for inflammatory diseases
WO2010081823A1 (en) 2009-01-13 2010-07-22 Proteosys Ag Pirenzepine as otoprotective agent
CN103242246A (zh) * 2013-05-21 2013-08-14 苏州科捷生物医药有限公司 3-位取代的n-甲基哌嗪的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel

Also Published As

Publication number Publication date
BG28711A3 (en) 1980-06-16
PH14609A (en) 1981-10-02
HU180999B (en) 1983-05-30
PL207191A1 (pl) 1979-07-16
CA1109064A (en) 1981-09-15
MY8200242A (en) 1982-12-31
PL214169A1 (no) 1979-11-05
DD137106A5 (de) 1979-08-15
NO149313B (no) 1983-12-19
IE46907B1 (en) 1983-11-02
DK239578A (da) 1978-12-01
FI63232B (fi) 1983-01-31
NL7805847A (nl) 1978-12-04
IE781071L (en) 1978-11-30
AU3662278A (en) 1979-12-06
PT68112A (de) 1978-06-01
HK11182A (en) 1982-03-19
ES473441A1 (es) 1979-05-01
CH637652A5 (de) 1983-08-15
AU516893B2 (en) 1981-06-25
ES470270A1 (es) 1979-01-01
IL54813A0 (en) 1978-07-31
FR2392993B1 (no) 1981-06-26
BG26949A4 (bg) 1979-07-12
FR2392993A1 (fr) 1978-12-29
BE867638A (fr) 1978-11-30
GB1571781A (en) 1980-07-16
AT361491B (de) 1981-03-10
PL113628B1 (en) 1980-12-31
GR66164B (no) 1981-01-20
NO149313C (no) 1984-03-28
JPS543096A (en) 1979-01-11
US4213984A (en) 1980-07-22
SU772484A3 (ru) 1980-10-15
IL54813A (en) 1982-02-28
NO781878L (no) 1978-12-01
FI781474A (fi) 1978-12-01
FI63232C (fi) 1983-05-10
CS207617B2 (en) 1981-08-31
SE7806288L (sv) 1978-12-01
ATA367878A (de) 1980-08-15
NZ187426A (en) 1981-10-19
PL112911B1 (en) 1980-11-29
DE2724434A1 (de) 1979-02-22

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