ZA732791B - Benzoxazole derivatives - Google Patents
Benzoxazole derivativesInfo
- Publication number
- ZA732791B ZA732791B ZA732791A ZA732791A ZA732791B ZA 732791 B ZA732791 B ZA 732791B ZA 732791 A ZA732791 A ZA 732791A ZA 732791 A ZA732791 A ZA 732791A ZA 732791 B ZA732791 B ZA 732791B
- Authority
- ZA
- South Africa
- Prior art keywords
- benzoxazole derivatives
- benzoxazole
- derivatives
- Prior art date
Links
- BCMCBBGGLRIHSE-UHFFFAOYSA-N 1,3-benzoxazole Chemical class C1=CC=C2OC=NC2=C1 BCMCBBGGLRIHSE-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D263/57—Aryl or substituted aryl radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2340972A GB1435721A (en) | 1972-05-18 | 1972-05-18 | Benzoxazole derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA732791B true ZA732791B (en) | 1974-12-24 |
Family
ID=10195157
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA732791A ZA732791B (en) | 1972-05-18 | 1973-04-25 | Benzoxazole derivatives |
Country Status (31)
Country | Link |
---|---|
US (1) | US3912748A (fr) |
JP (6) | JPS5912672B2 (fr) |
KR (1) | KR780000234B1 (fr) |
AR (4) | AR230991A1 (fr) |
AT (1) | AT333752B (fr) |
BE (1) | BE799790A (fr) |
BG (1) | BG21408A3 (fr) |
CA (1) | CA1029019A (fr) |
CH (5) | CH595361A5 (fr) |
CS (1) | CS200455B2 (fr) |
CY (1) | CY1016A (fr) |
DD (1) | DD105229A5 (fr) |
DE (1) | DE2324443A1 (fr) |
DK (1) | DK140340B (fr) |
ES (1) | ES414863A1 (fr) |
FR (2) | FR2184966B1 (fr) |
GB (1) | GB1435721A (fr) |
HK (1) | HK72579A (fr) |
HU (1) | HU167933B (fr) |
IE (2) | IE37564B1 (fr) |
IL (2) | IL42102A (fr) |
KE (1) | KE2975A (fr) |
MY (1) | MY8000063A (fr) |
NL (1) | NL170145C (fr) |
PH (3) | PH9685A (fr) |
PL (3) | PL89247B1 (fr) |
RO (2) | RO66278A (fr) |
SE (3) | SE386174B (fr) |
SU (3) | SU574157A3 (fr) |
YU (3) | YU130473A (fr) |
ZA (1) | ZA732791B (fr) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3888864A (en) | 1973-06-29 | 1975-06-10 | Hoffmann La Roche | Amino lower alkyl ether derivatives of opium alkaloids |
GB1495488A (en) * | 1976-06-23 | 1977-12-21 | Ippco Int Pharma Patents Co Es | Optically active 2-(2-phenyl-5-benzoxazolyl)propionic acids |
US4087437A (en) * | 1976-09-07 | 1978-05-02 | Eli Lilly And Company | 2-Phenyl-5-benzoxazolylalkanoic acid purification process |
GB1590587A (en) * | 1977-06-28 | 1981-06-03 | Lilly Industries Ltd | Benoxaprofen |
IT1099589B (it) * | 1978-08-04 | 1985-09-18 | Ravizza Spa | Processo per la preparazione di derivati dell'acido benzoxazolil propionico |
CA1125768A (fr) * | 1978-10-31 | 1982-06-15 | Hoffmann-La Roche Limited | Derives de benzoxazole |
GB2058381B (en) | 1979-07-18 | 1983-01-19 | Fuji Photo Film Co Ltd | Colour photographic light-sensitive material containing dye-releasing redox compound |
GR75153B (fr) * | 1981-03-27 | 1984-07-13 | Lilly Co Eli | |
IT1157295B (it) * | 1982-07-19 | 1987-02-11 | Ravizza Spa | Processo perfezionato per la preparazione di derivati dell'acido benzoxazolil propionico |
DE3413875A1 (de) * | 1984-04-12 | 1985-10-17 | Ludwig Heumann & Co GmbH, 8500 Nürnberg | Benzothiazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltendes arzneimittel |
IT1177017B (it) * | 1984-10-22 | 1987-08-26 | Ravizza Spa | Processo per la preparazione dell'acido 2(4-flurofenil)alfa-metil-5-benzox azoloacetico |
US4873259A (en) * | 1987-06-10 | 1989-10-10 | Abbott Laboratories | Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds |
US4822809A (en) * | 1987-11-13 | 1989-04-18 | Abbott Laboratories | Benzazole lipoxygenase inhibiting compounds |
IT1233836B (it) * | 1988-01-13 | 1992-04-21 | Euroresearch Srl | Sali idrosolubili dell'acido (+)2-(4 fluorofenil)-alfa-metil-5 benzoxazolo acetato. |
UA83620C2 (ru) * | 2001-12-05 | 2008-08-11 | Уайт | Замещенные бензоксазолы и их аналоги как эстрогенные агенты |
WO2004046122A2 (fr) * | 2002-11-16 | 2004-06-03 | Oxford Glycosciences (Uk) Ltd | Derives d'acides de benzoxazole, de benzothiazole, et de benzimidazole pharmaceutiquement actifs |
JP4790594B2 (ja) * | 2003-02-25 | 2011-10-12 | トポターゲット ユーケー リミテッド | Hdacインヒビターとしての、二環式ヘテロアリール基を含むヒドロキサム酸化合物 |
CA2589495C (fr) * | 2004-12-15 | 2013-10-01 | Dompe Pha.R.Ma. S.P.A. | Derives de l'acide 2-arylpropionique et compositions pharmaceutiques contenant ceux-ci |
EP1888548B1 (fr) | 2005-05-26 | 2012-08-22 | Neuron Systems, Inc | Dérivé de quinoline pour le traitement de maladies rétiniennes |
JP5369854B2 (ja) | 2008-04-21 | 2013-12-18 | 住友化学株式会社 | 有害節足動物防除組成物および縮合複素環化合物 |
US9687481B2 (en) | 2013-01-23 | 2017-06-27 | Aldeyra Therapeutics, Inc. | Toxic aldehyde related diseases and treatment |
AU2014209585A1 (en) | 2013-01-25 | 2015-07-23 | Aldeyra Therapeutics, Inc. | Novel traps in the treatment of macular degeneration |
US20170298081A1 (en) * | 2014-08-08 | 2017-10-19 | Kasuma Partners Inc. | Condensed heterocyclic compound |
AU2016311158A1 (en) | 2015-08-21 | 2018-04-05 | Aldeyra Therapeutics, Inc. | Deuterated compounds and uses thereof |
MX2018013472A (es) | 2016-05-09 | 2019-02-28 | Aldeyra Therapeutics Inc | Tratamiento de combinacion de trastornos y enfermedades inflamatorios oculares. |
EP3596040B1 (fr) | 2017-03-16 | 2023-10-11 | Aldeyra Therapeutics, Inc. | Composés polymorphes de sels de 6-chloro-3-amino-2(2-hydroxypropyl)quinoline et leurs utilisations |
AU2018348174A1 (en) | 2017-10-10 | 2020-04-23 | Aldeyra Therapeutics, Inc. | Treatment of inflammatory disorders |
CN112714762A (zh) | 2018-08-06 | 2021-04-27 | 奥尔德拉医疗公司 | 多晶型化合物及其用途 |
WO2020068986A1 (fr) | 2018-09-25 | 2020-04-02 | Aldeyra Therapeutics, Inc. | Formulations pour le traitement de la maladie de l'œil sec |
JP2022526917A (ja) | 2019-03-26 | 2022-05-27 | アルデイラ セラピューティクス, インコーポレイテッド | 眼科用製剤およびその使用 |
EP3962894A4 (fr) | 2019-05-02 | 2023-01-11 | Aldeyra Therapeutics, Inc. | Composés polymorphes et leurs utilisations |
WO2021231792A1 (fr) | 2020-05-13 | 2021-11-18 | Aldeyra Therapeutics, Inc. | Formulations pharmaceutiques et leurs utilisations |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD70860A (fr) * | ||||
NL285932A (fr) * | 1961-11-27 | |||
CH516339A (de) * | 1969-03-03 | 1971-12-15 | Ciba Geigy Ag | Verwendung von Azolverbindungen als Antioxydantien |
DE2118315C3 (de) * | 1970-04-20 | 1975-04-03 | Sumitomo Chemical Co., Ltd., Osaka (Japan) | 2-(1H)-Chinazolinonderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
IL37633A (en) * | 1970-09-10 | 1975-08-31 | Merck & Co Inc | 2-(4-(2-benzoxazolyl)phenyl)alkanoic acid derivatives |
DE2115926C3 (de) * | 1971-04-01 | 1978-05-03 | C.H. Boehringer Sohn, 6507 Ingelheim | 1 -(4-Hydroxy-3-dimethylaminosuIfamidophenyI)-2-aminoäthanderivate, Verfahren zu ihrer Herstellung und diese enthaltende Mittel |
GB1491863A (en) * | 1973-10-23 | 1977-11-16 | Lilly Industries Ltd | 2,5-or 2,6-disubstituted benzoxazoles |
GB1590587A (en) * | 1977-06-28 | 1981-06-03 | Lilly Industries Ltd | Benoxaprofen |
-
1972
- 1972-05-18 GB GB2340972A patent/GB1435721A/en not_active Expired
-
1973
- 1973-04-25 ZA ZA732791A patent/ZA732791B/xx unknown
- 1973-04-25 IE IE1898/76A patent/IE37564B1/xx unknown
- 1973-04-25 IL IL42102A patent/IL42102A/en unknown
- 1973-04-28 IE IE648/73A patent/IE37563B1/xx unknown
- 1973-05-01 US US356251A patent/US3912748A/en not_active Expired - Lifetime
- 1973-05-01 CA CA170,186A patent/CA1029019A/fr not_active Expired
- 1973-05-07 PH PH14592*UA patent/PH9685A/en unknown
- 1973-05-11 AR AR247979A patent/AR230991A1/es active
- 1973-05-15 DE DE2324443A patent/DE2324443A1/de not_active Ceased
- 1973-05-15 CY CY1016A patent/CY1016A/xx unknown
- 1973-05-16 HU HULI244A patent/HU167933B/hu not_active IP Right Cessation
- 1973-05-16 KR KR7300790A patent/KR780000234B1/ko active
- 1973-05-16 CS CS733508A patent/CS200455B2/cs unknown
- 1973-05-16 DD DD170872A patent/DD105229A5/xx unknown
- 1973-05-17 CH CH1621275A patent/CH595361A5/xx not_active IP Right Cessation
- 1973-05-17 CH CH1298676A patent/CH594643A5/xx not_active IP Right Cessation
- 1973-05-17 CH CH1298576A patent/CH595362A5/xx not_active IP Right Cessation
- 1973-05-17 AT AT432573A patent/AT333752B/de not_active IP Right Cessation
- 1973-05-17 ES ES414863A patent/ES414863A1/es not_active Expired
- 1973-05-17 CH CH703673A patent/CH592071A5/xx not_active IP Right Cessation
- 1973-05-17 JP JP48055110A patent/JPS5912672B2/ja not_active Expired
- 1973-05-17 SE SE7307005A patent/SE386174B/xx unknown
- 1973-05-17 YU YU01304/73A patent/YU130473A/xx unknown
- 1973-05-17 CH CH1621375A patent/CH587834A5/xx not_active IP Right Cessation
- 1973-05-17 DK DK274673AA patent/DK140340B/da not_active IP Right Cessation
- 1973-05-17 FR FR7317894A patent/FR2184966B1/fr not_active Expired
- 1973-05-17 SU SU7301916802A patent/SU574157A3/ru active
- 1973-05-18 PL PL1973162653A patent/PL89247B1/pl unknown
- 1973-05-18 RO RO7374829A patent/RO66278A/fr unknown
- 1973-05-18 BG BG023657A patent/BG21408A3/xx unknown
- 1973-05-18 NL NLAANVRAGE7307018,A patent/NL170145C/xx not_active IP Right Cessation
- 1973-05-18 PL PL1973183011A patent/PL94208B1/pl unknown
- 1973-05-18 BE BE6044169A patent/BE799790A/fr not_active IP Right Cessation
- 1973-05-18 PL PL1973182614A patent/PL92565B1/pl unknown
- 1973-05-18 RO RO7384621A patent/RO66800A/fr unknown
-
1974
- 1974-11-21 PH PH16542A patent/PH10704A/en unknown
- 1974-11-21 PH PH16541A patent/PH11718A/en unknown
- 1974-11-29 SU SU7402079273A patent/SU582762A3/ru active
- 1974-11-29 SU SU7402079274A patent/SU580837A3/ru active
-
1975
- 1975-01-01 AR AR257863A patent/AR205021A1/es active
- 1975-01-01 AR AR257862A patent/AR207857A1/es active
- 1975-06-12 FR FR7518361A patent/FR2284592A1/fr active Granted
- 1975-08-22 SE SE7509387A patent/SE434399B/xx not_active IP Right Cessation
- 1975-12-23 IL IL48711A patent/IL48711A0/xx unknown
-
1976
- 1976-03-06 AR AR257861A patent/AR212010A1/es active
-
1977
- 1977-09-21 SE SE7710602A patent/SE435838B/xx not_active IP Right Cessation
-
1979
- 1979-05-17 YU YU1171/79A patent/YU36298B/xx unknown
- 1979-05-17 YU YU01170/79A patent/YU117079A/xx unknown
- 1979-07-03 KE KE2975A patent/KE2975A/xx unknown
- 1979-10-11 HK HK725/79A patent/HK72579A/xx unknown
-
1980
- 1980-12-31 MY MY198063A patent/MY8000063A/xx unknown
-
1981
- 1981-05-13 JP JP7212281A patent/JPS56167674A/ja active Pending
- 1981-05-13 JP JP56072123A patent/JPS5929185B2/ja not_active Expired
- 1981-05-13 JP JP7212481A patent/JPS56167675A/ja active Pending
- 1981-05-13 JP JP7212181A patent/JPS56167673A/ja active Pending
-
1984
- 1984-02-02 JP JP59017637A patent/JPS6021976B2/ja not_active Expired
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