CH594643A5 - - Google Patents

Info

Publication number
CH594643A5
CH594643A5 CH1298676A CH1298676A CH594643A5 CH 594643 A5 CH594643 A5 CH 594643A5 CH 1298676 A CH1298676 A CH 1298676A CH 1298676 A CH1298676 A CH 1298676A CH 594643 A5 CH594643 A5 CH 594643A5
Authority
CH
Switzerland
Application number
CH1298676A
Inventor
Delme Evans
David William Dunwell
Terence Alan Hicks
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of CH594643A5 publication Critical patent/CH594643A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D263/57—Aryl or substituted aryl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
CH1298676A 1972-05-18 1973-05-17 CH594643A5 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2340972A GB1435721A (en) 1972-05-18 1972-05-18 Benzoxazole derivatives

Publications (1)

Publication Number Publication Date
CH594643A5 true CH594643A5 (xx) 1978-01-13

Family

ID=10195157

Family Applications (5)

Application Number Title Priority Date Filing Date
CH1621275A CH595361A5 (xx) 1972-05-18 1973-05-17
CH1621375A CH587834A5 (xx) 1972-05-18 1973-05-17
CH1298676A CH594643A5 (xx) 1972-05-18 1973-05-17
CH1298576A CH595362A5 (xx) 1972-05-18 1973-05-17
CH703673A CH592071A5 (xx) 1972-05-18 1973-05-17

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CH1621275A CH595361A5 (xx) 1972-05-18 1973-05-17
CH1621375A CH587834A5 (xx) 1972-05-18 1973-05-17

Family Applications After (2)

Application Number Title Priority Date Filing Date
CH1298576A CH595362A5 (xx) 1972-05-18 1973-05-17
CH703673A CH592071A5 (xx) 1972-05-18 1973-05-17

Country Status (31)

Country Link
US (1) US3912748A (xx)
JP (6) JPS5912672B2 (xx)
KR (1) KR780000234B1 (xx)
AR (4) AR230991A1 (xx)
AT (1) AT333752B (xx)
BE (1) BE799790A (xx)
BG (1) BG21408A3 (xx)
CA (1) CA1029019A (xx)
CH (5) CH595361A5 (xx)
CS (1) CS200455B2 (xx)
CY (1) CY1016A (xx)
DD (1) DD105229A5 (xx)
DE (1) DE2324443A1 (xx)
DK (1) DK140340B (xx)
ES (1) ES414863A1 (xx)
FR (2) FR2184966B1 (xx)
GB (1) GB1435721A (xx)
HK (1) HK72579A (xx)
HU (1) HU167933B (xx)
IE (2) IE37564B1 (xx)
IL (2) IL42102A (xx)
KE (1) KE2975A (xx)
MY (1) MY8000063A (xx)
NL (1) NL170145C (xx)
PH (3) PH9685A (xx)
PL (3) PL92565B1 (xx)
RO (2) RO66800A (xx)
SE (3) SE386174B (xx)
SU (3) SU574157A3 (xx)
YU (3) YU130473A (xx)
ZA (1) ZA732791B (xx)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888864A (en) 1973-06-29 1975-06-10 Hoffmann La Roche Amino lower alkyl ether derivatives of opium alkaloids
GB1495488A (en) * 1976-06-23 1977-12-21 Ippco Int Pharma Patents Co Es Optically active 2-(2-phenyl-5-benzoxazolyl)propionic acids
US4087437A (en) * 1976-09-07 1978-05-02 Eli Lilly And Company 2-Phenyl-5-benzoxazolylalkanoic acid purification process
GB1590587A (en) * 1977-06-28 1981-06-03 Lilly Industries Ltd Benoxaprofen
IT1099589B (it) * 1978-08-04 1985-09-18 Ravizza Spa Processo per la preparazione di derivati dell'acido benzoxazolil propionico
CA1125768A (en) * 1978-10-31 1982-06-15 Hoffmann-La Roche Limited Benzoxazole derivatives
GB2058381B (en) 1979-07-18 1983-01-19 Fuji Photo Film Co Ltd Colour photographic light-sensitive material containing dye-releasing redox compound
GR75153B (xx) * 1981-03-27 1984-07-13 Lilly Co Eli
IT1157295B (it) * 1982-07-19 1987-02-11 Ravizza Spa Processo perfezionato per la preparazione di derivati dell'acido benzoxazolil propionico
DE3413875A1 (de) * 1984-04-12 1985-10-17 Ludwig Heumann & Co GmbH, 8500 Nürnberg Benzothiazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltendes arzneimittel
IT1177017B (it) * 1984-10-22 1987-08-26 Ravizza Spa Processo per la preparazione dell'acido 2(4-flurofenil)alfa-metil-5-benzox azoloacetico
US4873259A (en) * 1987-06-10 1989-10-10 Abbott Laboratories Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds
US4822809A (en) * 1987-11-13 1989-04-18 Abbott Laboratories Benzazole lipoxygenase inhibiting compounds
IT1233836B (it) * 1988-01-13 1992-04-21 Euroresearch Srl Sali idrosolubili dell'acido (+)2-(4 fluorofenil)-alfa-metil-5 benzoxazolo acetato.
UA83620C2 (ru) * 2001-12-05 2008-08-11 Уайт Замещенные бензоксазолы и их аналоги как эстрогенные агенты
WO2004046122A2 (en) * 2002-11-16 2004-06-03 Oxford Glycosciences (Uk) Ltd Benzoxazole, benzthiazole and benzimidazole acid derivatives and their use as heparanase inhibitors
JP4790594B2 (ja) * 2003-02-25 2011-10-12 トポターゲット ユーケー リミテッド Ｈｄａｃインヒビターとしての、二環式ヘテロアリール基を含むヒドロキサム酸化合物
ATE423760T1 (de) * 2004-12-15 2009-03-15 Dompe Pha R Ma Spa Res & Mfg 2-arylpropionsäurederivate und pharmazeutische zusammensetzungen, die diese enthalten
US8940764B2 (en) 2005-05-26 2015-01-27 Aldexa Therapeutics, Inc. Compositions and methods of treating retinal disease
JP5369854B2 (ja) * 2008-04-21 2013-12-18 住友化学株式会社 有害節足動物防除組成物および縮合複素環化合物
CN111135171B (zh) 2013-01-23 2023-09-08 奥尔德拉医疗公司 与毒性醛相关的疾病和治疗
AU2014209585A1 (en) 2013-01-25 2015-07-23 Aldeyra Therapeutics, Inc. Novel traps in the treatment of macular degeneration
EP3178810A4 (en) * 2014-08-08 2018-07-04 Kasuma Partners Inc. Condensed heterocyclic compound
WO2017035077A1 (en) 2015-08-21 2017-03-02 Aldeyra Therapeutics, Inc. Deuterated compounds and uses thereof
CA3022665A1 (en) 2016-05-09 2017-11-16 Aldeyra Therapeutics, Inc. Combination treatment of ocular inflammatory disorders and diseases
CA3054811A1 (en) 2017-03-16 2018-09-20 Aldeyra Therapeutics, Inc. Polymorphic compounds and uses thereof
CN111356451A (zh) 2017-10-10 2020-06-30 奥尔德拉医疗公司 炎性病症的治疗
CN112714762A (zh) 2018-08-06 2021-04-27 奥尔德拉医疗公司 多晶型化合物及其用途
US11197821B2 (en) 2018-09-25 2021-12-14 Aldeyra Therapeutics, Inc. Formulations for treatment of dry eye disease
US11786518B2 (en) 2019-03-26 2023-10-17 Aldeyra Therapeutics, Inc. Ophthalmic formulations and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD70860A (xx) *
NL285932A (xx) * 1961-11-27
CH516339A (de) * 1969-03-03 1971-12-15 Ciba Geigy Ag Verwendung von Azolverbindungen als Antioxydantien
DE2118315C3 (de) * 1970-04-20 1975-04-03 Sumitomo Chemical Co., Ltd., Osaka (Japan) 2-(1H)-Chinazolinonderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
IL37633A (en) * 1970-09-10 1975-08-31 Merck & Co Inc 2-(4-(2-benzoxazolyl)phenyl)alkanoic acid derivatives
DE2115926C3 (de) * 1971-04-01 1978-05-03 C.H. Boehringer Sohn, 6507 Ingelheim 1 -(4-Hydroxy-3-dimethylaminosuIfamidophenyI)-2-aminoäthanderivate, Verfahren zu ihrer Herstellung und diese enthaltende Mittel
GB1491863A (en) * 1973-10-23 1977-11-16 Lilly Industries Ltd 2,5-or 2,6-disubstituted benzoxazoles
GB1590587A (en) * 1977-06-28 1981-06-03 Lilly Industries Ltd Benoxaprofen

Also Published As

Publication number Publication date
AU5590773A (en) 1974-11-21
CH595361A5 (xx) 1978-02-15
CS200455B2 (en) 1980-09-15
IL48711A0 (en) 1976-02-29
RO66800A (ro) 1982-03-24
JPS6021976B2 (ja) 1985-05-30
SU580837A3 (ru) 1977-11-15
JPS4954363A (xx) 1974-05-27
NL170145B (nl) 1982-05-03
JPS56167645A (en) 1981-12-23
JPS59161346A (ja) 1984-09-12
HK72579A (en) 1979-10-19
PH11718A (en) 1978-05-30
AR205021A1 (es) 1976-03-31
MY8000063A (en) 1980-12-31
SE435838B (sv) 1984-10-22
CH587834A5 (xx) 1977-05-13
FR2184966A1 (xx) 1973-12-28
PL89247B1 (xx) 1976-11-30
JPS5912672B2 (ja) 1984-03-24
KR780000234B1 (en) 1978-07-01
JPS56167673A (en) 1981-12-23
DK140340C (xx) 1979-12-31
FR2284592A1 (fr) 1976-04-09
ATA432573A (de) 1976-04-15
SE386174B (sv) 1976-08-02
SE7509387L (sv) 1975-08-22
SE434399B (sv) 1984-07-23
SU574157A3 (ru) 1977-09-25
BE799790A (fr) 1973-11-19
JPS5929185B2 (ja) 1984-07-18
NL170145C (nl) 1982-10-01
SU582762A3 (ru) 1977-11-30
US3912748A (en) 1975-10-14
CY1016A (en) 1979-11-23
JPS56167674A (en) 1981-12-23
ES414863A1 (es) 1976-02-01
AR230991A1 (es) 1984-08-31
PH9685A (en) 1976-02-10
ZA732791B (en) 1974-12-24
CA1029019A (en) 1978-04-04
CH592071A5 (xx) 1977-10-14
IE37563B1 (en) 1977-08-17
IL42102A (en) 1977-07-31
FR2184966B1 (xx) 1979-01-12
YU117179A (en) 1981-08-31
BG21408A3 (xx) 1976-05-20
YU36298B (en) 1982-06-18
PH10704A (en) 1977-08-24
DE2324443A1 (de) 1973-11-29
JPS56167675A (en) 1981-12-23
RO66278A (ro) 1981-06-26
IE37564B1 (en) 1977-08-17
NL7307018A (xx) 1973-11-20
AR207857A1 (es) 1976-11-08
KE2975A (en) 1979-07-20
FR2284592B1 (xx) 1979-01-05
PL94208B1 (xx) 1977-07-30
YU130473A (en) 1981-08-31
DD105229A5 (xx) 1974-04-12
IE37563L (en) 1973-11-18
SE7710602L (sv) 1977-09-21
GB1435721A (en) 1976-05-12
YU117079A (en) 1981-08-31
IL42102A0 (en) 1973-06-29
IE37564L (en) 1973-11-18
HU167933B (xx) 1976-01-28
PL92565B1 (xx) 1977-04-30
DK140340B (da) 1979-08-06
AR212010A1 (es) 1978-04-28
CH595362A5 (xx) 1978-02-15
AT333752B (de) 1976-12-10

Similar Documents

Publication Publication Date Title
DK140340C (xx)
JPS5247808Y2 (xx)
JPS5246651B2 (xx)
JPS4927491A (xx)
JPS514923Y2 (xx)
JPS5145125Y2 (xx)
FR2169536A5 (xx)
CS155484B1 (xx)
JPS4970190U (xx)
JPS48102075A (xx)
CS157361B1 (xx)
CS156936B1 (xx)
CS157338B1 (xx)
CS157401B1 (xx)
CH599089A5 (xx)
CH571393A5 (xx)
BG18019A1 (xx)
DD96799A1 (xx)
BG18026A1 (xx)
CH607041A5 (xx)
CH606461A5 (xx)
CH602533A5 (xx)
CH601306A5 (xx)
CH599098A5 (xx)
CH573188A5 (xx)

Legal Events

Date Code Title Description
PL Patent ceased